E. Kilgour

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Growth Hormone-dependent Differentiation of 3T3-F442A Preadipocytes Requires Janus Kinase/Signal Transducer and Activator of Transcription but Not Mitogen-activated Protein Kinase or p70 S6 Kinase Signaling*

M. Houslay, G. J. Sale, N. Anderson, 1999, The Journal of Biological Chemistry.

Activation of mitogen-activated protein kinase in BC3H1 myocytes by fluoroaluminate.

T. Sturgill, N. Anderson, E. Kilgour, 1991, The Journal of biological chemistry.

Requirement for phosphoinositide 3-OH kinase in growth hormone signalling to the mitogen-activated protein kinase and p70s6k pathways.

I. Gout, N. Anderson, E. Kilgour, 1996, The Biochemical journal.

Growth hormone decreases the response to anti-lipolytic agonists and decreases the levels of Gi2 in rat adipocytes.

M. Houslay, E. Kilgour, R. Vernon, 1994, The Biochemical journal.

Cyclic AMP potentiates growth hormone-dependent differentiation of 3T3-F442A preadipocytes: Possible involvement of the transcription factor CREB

N. Anderson, S. Yarwood, E. Kilgour, 1998, Molecular and Cellular Endocrinology.

Changes in the expression of guanine nucleotide‐binding proteins during differentiation of 3T3‐F442A cells in a hormonally defined medium

N. Anderson, E. Kilgour, 1993, FEBS letters.

Regulation of the GTP-binding protein-based antilipolytic system of sheep adipocytes by growth hormone.

M. Houslay, E. Kilgour, R. Vernon, 1998, The Journal of endocrinology.

AZD7545, a novel inhibitor of pyruvate dehydrogenase kinase 2 (PDHK2), activates pyruvate dehydrogenase in vivo and improves blood glucose control in obese (fa/fa) Zucker rats.

D. Martin, E. Kilgour, J. Orme, 2003, Biochemical Society transactions.

Chronic effects of somatotropin treatment on response of subcutaneous adipose tissue lipolysis to acutely acting factors in vivo and in vitro.

M. Houslay, E. Finley, E. Kilgour, 1996, Journal of animal science.

Subcellular localization and hormone sensitivity of adipocyte cyclic AMP phosphodiesterase.

M. Houslay, N. Anderson, E. Kilgour, 1989, The Biochemical journal.

Activation and phosphorylation of the 'dense-vesicle' high-affinity cyclic AMP phosphodiesterase by cyclic AMP-dependent protein kinase.

M. Houslay, N. Anderson, E. Kilgour, 1989, The Biochemical journal.

AZD7545 is a selective inhibitor of pyruvate dehydrogenase kinase 2.

T. Roche, E. Kilgour, J. Orme, 2003, Biochemical Society transactions.

Glucagon activates two distinct signal transduction systems in hepatocytes, which leads to the desensitization of G-protein-regulated adenylate cyclase, the phosphorylation and inactivation of Gi-2 and the phosphorylation and stimulation of a specific cyclic AMP phosphodiesterase

M. Houslay, N. Pyne, E. Kilgour, 1990 .

Identification and optimisation of 3,3-dimethyl-azetidin-2-ones as potent and selective inhibitors of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1)

S. Steinbacher, M. Augustin, D. Ogg, 2014 .

A role for inositol-glycan mediators and G-proteins in insulin action.

E. Kilgour, 1993, Cellular signalling.

The generation of inositolglycan mediators from rat liver plasma membranes: the role of guanine nucleotide binding proteins.

E. Kilgour, G. Romero, J. Larner,, 1992, Biochemical and biophysical research communications.

A pertussis toxin-sensitive G-protein mediates some aspects of insulin action in BC3H-1 murine myocytes.

L. Luttrell, E. Kilgour, G. Romero, 1990, The Journal of biological chemistry.

Duality in the mechanism of action of insulin.

E. Kilgour, D. B. Houston, L. Huang, 1990, Advances in second messenger and phosphoprotein research.

Targeting Non-Small Cell Lung Cancer Cells by Dual Inhibition of the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor

E. E. Vincent, J. Tavaré, I. Hers, 2013, PloS one.

Protein kinase C isoforms play differential roles in the regulation of adipocyte differentiation.

M. Houslay, N. Anderson, S. Mackenzie, 1998, The Biochemical journal.

Novel acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329).

Martin J Packer, Nidhal Selmi, Andrew Stocker, 2012, Journal of medicinal chemistry.

Growth hormone induces the tyrosine phosphorylation and nuclear accumulation of components of the ISGF3 transcription factor complex

N. Anderson, E. Kilgour, 1994, FEBS letters.

PDH kinase inhibitors: a novel therapy for Type II diabetes?

E. Kilgour, B. Leighton, B Leighton, 2005, Biochemical Society transactions.

Cyclic AMP stimulates the phosphorylation and activation of p42 and p44 mitogen-activated protein kinases in 3T3-F442A preadipocytes.

N. Anderson, S. Yarwood, E. Kilgour, 1996, Biochemical and biophysical research communications.

The effect of noradrenaline on pyruvate dehydrogenase activity of rat white adipose tissue in vivo

E. Kilgour, R. Vernon, 1986 .

Growth hormone and phorbol esters require specific protein kinase C isoforms to activate mitogen-activated protein kinases in 3T3-F442A cells.

M. Houslay, N. Anderson, S. Mackenzie, 1997, The Biochemical journal.

Tissue-specific changes in the ability of insulin and noradrenaline to activate pyruvate dehydrogenase in vivo during lactation in the rat.

E. Kilgour, R. Vernon, 1987, The Biochemical journal.

Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017).

Martin J Packer, Nidhal Selmi, David Hargreaves, 2012, Journal of medicinal chemistry.

Reduction of acyl glucuronidation in a series of acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors: the discovery of AZD6925

James S. Scott, N. Selmi, M. Packer, 2012 .

Catecholamine activation of pyruvate dehydrogenase in white adipose tissue of the rat in vivo.

E. Kilgour, R. Vernon, 1987, The Biochemical journal.

D. Hargreaves, D. Ogg, James S. Scott, 2012, Journal of medicinal chemistry.

Effects of lactation on the signal transduction systems regulating lipolysis in sheep subcutaneous and omental adipose tissue.

M. Houslay, E. Finley, E. Kilgour, 1995, The Biochemical journal.

Effect of lactation on insulin signal transduction in sheep adipose tissue and skeletal muscle.

E. Finley, P. Buttery, E. Kilgour, 1996, The Journal of endocrinology.