N. Seki

发表

Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation

M. Kubo, A. Yoshimura, T. Naka, 2002, Proceedings of the National Academy of Sciences of the United States of America.

The IL-4 production capability of different strains of naive CD4(+) T cells controls the direction of the T(h) cell response.

M. Kubo, Ryoji Yagi, N. Seki, 2002, International immunology.

Milk fat globule epidermal growth factor 8 (MFG-E8) on monocytes is a novel biomarker of disease activity in systemic lupus erythematosus

T. Takeuchi, J. Kikuchi, Katsuya Suzuki, 2020, Lupus.

Significant association between clinical characteristics and changes in peripheral immuno-phenotype in large vessel vasculitis

T. Takeuchi, Katsuya Suzuki, N. Seki, 2019, Arthritis Research & Therapy.

The Runx1 Transcription Factor Inhibits the Differentiation of Naive CD4+ T Cells into the Th2 Lineage by Repressing GATA3 Expression

M. Kubo, K. Hozumi, S. Habu, 2003, The Journal of experimental medicine.

Lymphadenopathy in IgG4-related disease: a phenotype of severe activity and poor prognosis, with eotaxin-3 as a new biomarker.

T. Takeuchi, J. Kikuchi, M. Akiyama, 2020, Rheumatology.

Distinct features between HLA-DR+ and HLA-DR- PD-1hi CXCR5- T peripheral helper cells in seropositive rheumatoid arthritis.

T. Takeuchi, Katsuya Suzuki, N. Seki, 2020, Rheumatology.

Proton-Pump Inhibitor and Tacrolimus use is Associated with Hypomagnesemia in Connective Tissue Disease: A Potential Pathogenic Link with Renal Deterioration and Recurrent Infections

T. Takeuchi, J. Kikuchi, N. Seki, 2020 .

The Runx 1 Transcription Factor Inhibits the Differentiation of Naive CD 4 T Cells into the Th 2 Lineage by Repressing GATA 3 Expression

M. Kubo, K. Hozumi, S. Habu, 2003 .

Role of sphingosine 1-phosphate (S1P) and effects of fingolimod, an S1P receptor 1 functional antagonist in lymphocyte circulation and autoimmune diseases

N. Seki, K. Sugahara, H. Kataoka, 2014 .

Sphingosine 1-phosphate receptor modulator, fingolimod (FTY720), provides a new therapeutic approach for autoimmune diseases

N. Seki, K. Sugahara, H. Kataoka, 2010 .

Fingolimod (FTY720), the Sphingosine 1-Phosphate Receptor Modulator, as a New Therapeutic Drug in Multiple Sclerosis

N. Seki, K. Sugahara, H. Kataoka, 2011 .

Fingolimod (FTY720) ameliorates experimental autoimmune encephalomyelitis (EAE): I. Oral administration of FTY720 effectively inhibits re- lapse of EAE

M. Koyama, N. Seki, K. Sugahara, 2010 .

Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow.

N. Seki, K. Sugahara, Y. Maeda, 2010, International immunology.

Role of Sphingosine 1-Phosphate (S1P) Receptor 1 in Experimental Autoimmune Encephalomyelitis —I

N. Seki, K. Sugahara, H. Kataoka, 2013 .

FTY720 induces the sequestration of circulating lymphocytes into the bone marrow in alymphoplasia mice

M. Koyama, N. Seki, K. Sugahara, 2010 .

Carbachol-induced secretion and homologous desensitization in rat basophilic leukemia (RBL-2H3) cells transfected with human m2 muscarinic acetylcholine receptors.

M. Uchida, N. Seki, K. Oishi, 2004, Journal of pharmacological sciences.

A New Phenylpyrazoleanilide, Y-320, Inhibits Interleukin 17 Production and Ameliorates Collagen-Induced Arthritis in Mice and Cynomolgus Monkeys

K. Adachi, N. Seki, K. Sugahara, 2013, Pharmaceuticals.

Role of Sphingosine 1-Phosphate ( S 1 P ) Receptor 1 in Experimental Autoimmune Encephalomyelitis — I . S 1 PS 1 P 1 Axis Induces Migration of Th 1 and Th 17 Cells

N. Seki, K. Sugahara, H. Kataoka, 2013 .

Cell Differentiation Time-Restricted Instruction Switch for Th2 IL-4-Induced GATA-3 Expression Is a

Frank Brombacher, Kenji Izuhara, Masato Kubo, 2013 .

IL-4-Induced GATA-3 Expression Is a Time-Restricted Instruction Switch for Th2 Cell Differentiation1

M. Kubo, K. Izuhara, F. Brombacher, 2004, The Journal of Immunology.

Role of interferons (IFNs) in the differentiation of T peripheral helper (Tph) cells 2. IFN-α and IFN-λ1 cooperatively contribute to the expansion of Tph cells in systemic lupus erythematosus.

T. Takeuchi, J. Kikuchi, Katsuya Suzuki, 2022, International immunology.

Longitudinal immune cell monitoring identified CD14++ CD16+ intermediate monocyte as a marker of relapse in patients with ANCA-associated vasculitis

T. Takeuchi, Katsuya Suzuki, N. Seki, 2020, Arthritis Research & Therapy.

Significant association between clinical characteristics and immuno-phenotypes in patients with ANCA-associated vasculitis.

T. Takeuchi, Katsuya Suzuki, N. Seki, 2019, Rheumatology.

Fingolimod (FTY720), sphingosine 1-phosphate receptor modulator, shows superior efficacy as compared with interferon-β in mouse experimental autoimmune encephalomyelitis.

M. Koyama, N. Seki, K. Sugahara, 2011, International immunopharmacology.

Therapeutic Effects of the Sphingosine 1-Phosphate Receptor Modulator, Fingolimod (FTY720), on Experimental Autoimmune Encephalomyelitis

N. Seki, K. Sugahara, H. Kataoka, 2012 .

Proton Pump Inhibitor and Tacrolimus Uses are Associated With Hypomagnesemia in Connective Tissue Disease: a Potential Link With Renal Dysfunction and Recurrent Infection

T. Takeuchi, J. Kikuchi, N. Seki, 2021, Frontiers in Pharmacology.

IL-17–Producing Vγ4+ γδ T Cells Require Sphingosine 1-Phosphate Receptor 1 for Their Egress from the Lymph Nodes under Homeostatic and Inflammatory Conditions

N. Seki, K. Sugahara, A. Fukunari, 2015, The Journal of Immunology.

A MOLECULAR NETWORK FOR FATIGUE IN PRIMARY SJÖGREN’S SYNDROME

T. Takeuchi, J. Kikuchi, K. Yamaoka, 2022 .

Fingolimod (FTY720) ameliorates experimental autoimmune encephalomyelitis (EAE)

M. Koyama, N. Seki, K. Sugahara, 2010 .

Carbachol-induced membrane ruffling and its desensitization in rat basophilic leukemia (RBL-2H3) cells transfected with m3 muscarinic acetylcholine receptors.

M. Uchida, N. Seki, K. Oishi, 2004, Biological and Pharmaceutical Bulletin.

Fingolimod (FTY720) ameliorates experimental autoimmune encephalomyelitis (EAE) : II. FTY720 decreases infiltration of Th17 and Th1 cells into the central nervous system in EAE

N. Seki, K. Sugahara, H. Kataoka, 2010 .

Th17/IL-17A axis is critical for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc): SSc patients with high levels of serum IL-17A exhibit reduced lung functions and increased prevalence of PAH.

M. Akiyama, N. Seki, K. Sugahara, 2024, Cytokine.

Cytotoxic Tph subset with low B-cell helper functions and its involvement in systemic lupus erythematosus

M. Akiyama, N. Seki, K. Sugahara, 2024, Communications biology.