I. Alvarez-Twose

发表

Evaluation of the WHO criteria for the classification of patients with mastocytosis

C. E. Pedreira, A. Órfão, C. Teodosio, 2011, Modern Pathology.

Impact of somatic and germline mutations on the outcome of systemic mastocytosis.

K. Roskin, J. Merker, Yan-li Hou, 2018, Blood advances.

mesenchymal stem cells in human bone marrow

A. Órfão, C. Teodosio, A. Amaral, 2015 .

Venom immunotherapy in patients with mastocytosis and hymenoptera venom anaphylaxis.

A. Órfão, I. Alvarez-Twose, D. González-de-Olano, 2011, Immunotherapy.

CD30 expression by bone marrow mast cells from different diagnostic variants of systemic mastocytosis

A. Órfão, C. Teodosio, T. George, 2013, Histopathology.

Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap

I. Alvarez-Twose, M. Piris-Villaespesa, 2020, Frontiers in Pharmacology.

Imatinib in systemic mastocytosis: a phase IV clinical trial in patients lacking exon 17 KIT mutations and review of the literature

A. Órfão, C. Teodosio, C. Caldas, 2016, Oncotarget.

Serum Tryptase Monitoring in Indolent Systemic Mastocytosis: Association with Disease Features and Patient Outcome

C. E. Pedreira, A. Órfão, C. Teodosio, 2013, PloS one.

Prognosis in adult indolent systemic mastocytosis: a long-term study of the Spanish Network on Mastocytosis in a series of 145 patients.

A. Órfão, C. Teodosio, J. Almeida, 2009, The Journal of allergy and clinical immunology.

Diagnosis of Adult Mastocytosis: Role for Bone Marrow Analysis

A. Órfão, C. Teodosio, J. Almeida, 2012 .

Current state of biology and diagnosis of clonal mast cell diseases in adults

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2012, International journal of laboratory hematology.

Comprehensive Analysis of Acquired Genetic Variants and Their Prognostic Impact in Systemic Mastocytosis

A. Órfão, I. Alvarez-Twose, A. García-Montero, 2022, Cancers.

Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect-induced anaphylaxis shows unique features versus other indolent SM.

A. Órfão, C. Teodosio, P. Bonadonna, 2014, The Journal of allergy and clinical immunology.

Immunophenotyping in systemic mastocytosis diagnosis: ‘CD25 positive’ alone is more informative than the ‘CD25 and/or CD2’ WHO criterion

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2012, Modern Pathology.

Evaluation of basophil activation in mastocytosis with Hymenoptera venom anaphylaxis

A. Órfão, B. D. L. H. Caballer, L. Sánchez-Muñoz, 2011, Cytometry. Part B, Clinical cytometry.

Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with Hymenoptera venom anaphylaxis.

M. Fernández-Rivas, A. Órfão, B. de la Hoz, 2008, The Journal of allergy and clinical immunology.

Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes.

A. Órfão, C. Teodosio, L. Schwartz, 2010, The Journal of allergy and clinical immunology.

Mast Cells as Key Players in Allergy and Inflammation.

I. Alvarez-Twose, D. González-de-Olano, 2018, Journal of investigational allergology & clinical immunology.

Adherence to immunotherapy in times of financial crisis.

I. Alvarez-Twose, D. González-de-Olano, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Selecting the Right Criteria and Proper Classification to Diagnose Mast Cell Activation Syndromes: A Critical Review.

G. Nilsson, M. Triggiani, A. Órfão, 2021, The journal of allergy and clinical immunology. In practice.

Anaphylaxis as a Clinical Manifestation of Clonal Mast Cell Disorders

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2014, Current Allergy and Asthma Reports.

Systemic mastocytosis as a risk factor for severe Hymenoptera sting-induced anaphylaxis.

A. Órfão, P. Bonadonna, L. Sánchez-Muñoz, 2013, The Journal of allergy and clinical immunology.

Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study.

E. Colado, A. Órfão, A. Reiter, 2021, The Lancet. Haematology.

MARS: Mutation-Adjusted Risk Score for Advanced Systemic Mastocytosis

T. Haferlach, A. Órfão, W. Hofmann, 2019, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology.

Massimo Triggiani, Olivier Hermine, Gunnar Nilsson, 2016, The Journal of allergy and clinical immunology.

Pediatric Mastocytosis

I. Alvarez-Twose, M. Carter, 2019, Mastocytosis.

Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome.

M. Triggiani, A. Órfão, H. Kluin-Nelemans, 2019, The journal of allergy and clinical immunology. In practice.

Cutaneous Mastocytosis With Predominant Infiltration of Promastocytes.

I. Alvarez-Twose, A. Matito, A. Torrelo, 2019, The American Journal of dermatopathology.

Characterization of CD34+ hematopoietic cells in systemic mastocytosis: Potential role in disease dissemination

A. Órfão, C. Teodosio, C. Caldas, 2018, Allergy.

Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors.

I. Alvarez-Twose, A. Matito, A. Torrelo, 2018, Immunology and allergy clinics of North America.

Patterns of Expression of CD25 and CD30 on Skin Mast Cells in Pediatric Mastocytosis

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2014 .

Childhood mastocytosis

I. Alvarez-Twose, L. Escribano, A. Torrelo, 2012, Current opinion in pediatrics.

Mast cell activation disorders presenting with cerebral vasospasm-related symptoms: a "Kounis-like" syndrome?

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2011, International journal of cardiology.

Short-term omalizumab treatment in an adolescent with cutaneous mastocytosis.

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Anemia, leukocytosis, abdominal pain, flushing, and bone and skin lesions

L. Sánchez-Muñoz, I. Alvarez-Twose, L. Escribano, 2012, Cleveland Clinic Journal of Medicine.

Proposed International Prognostic Scoring System for Mastocytosis (IPSM)

Akif, Perkins, M. Triggiani, 2019 .

Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis

M. Triggiani, A. Órfão, H. Kluin-Nelemans, 2014, Allergy.

An immature immunophenotype of bone marrow mast cells predicts for multilineage D816V KIT mutation in systemic mastocytosis

A. Órfão, C. Teodosio, J. Almeida, 2012, Leukemia.

Efficacy of avapritinib versus best available therapy in the treatment of advanced systemic mastocytosis

S. Dimitrijević, D. DeAngelo, I. Galinsky, 2022, Leukemia.

Efficacy and safety of avapritinib in advanced systemic mastocytosis: interim analysis of the phase 2 PATHFINDER trial

J. Panse, I. Dybedal, M. Deininger, 2021, Nature Medicine.

International prognostic scoring system for mastocytosis (IPSM): a retrospective cohort study.

M. Triggiani, A. Órfão, J. Panse, 2019, The Lancet. Haematology.

Flow cytometry in mastocytosis: utility as a diagnostic and prognostic tool.

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2014, Immunology and allergy clinics of North America.

Bone Marrow Expression of Mast Cell Disorders.

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2018, Immunology and allergy clinics of North America.

Systemic mastocytosis presenting as IgE-mediated food-induced anaphylaxis: A report of two cases.

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2015, The journal of allergy and clinical immunology. In practice.

Validation of the REMA Score for Predicting Mast Cell Clonality and Systemic Mastocytosis in Patients with Systemic Mast Cell Activation Symptoms

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2011, International Archives of Allergy and Immunology.

Response to celecoxib in a patient with indolent systemic mastocytosis presenting with intractable diarrhea.

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2015, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Clinical Impact of Pregnancy in Mastocytosis: A Study of the Spanish Network on Mastocytosis (REMA) in 45 Cases

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2011, International Archives of Allergy and Immunology.

Mastocytosis presenting as insect anaphylaxis: gender differences and natural history.

I. Alvarez-Twose, A. Matito, 2019, Current opinion in allergy and clinical immunology.

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2012, International journal of cardiology.

Altered innate immune profile in blood of systemic mastocytosis patients

C. E. Pedreira, A. Órfão, I. Criado, 2022, Clinical and translational allergy.

An Increase in Tryptase on the First Day of Hymenoptera Venom Immunotherapy Might Be a Predictor of Future Systemic Reactions During Treatment.

I. Alvarez-Twose, C. Blanco, J. M. Beitia, 2018, Journal of investigational allergology & clinical immunology.

Diagnosis and classification of mastocytosis in non‐specialized versus reference centres: a Spanish Network on Mastocytosis (REMA) study on 122 patients

A. Órfão, C. Teodosio, C. Caldas, 2016, British journal of haematology.

Extensive blistering is a predictor for severe complications in children with mastocytosis

J. Ring, A. Órfão, K. Brockow, 2012, Allergy.

Contribution of highly sensitive diagnostic methods to the diagnosis of systemic mastocytosis in the absence of skin lesions

A. Órfão, P. Kluin, A. Mulder, 2012, Allergy.

Venom immunotherapy in patients with clonal mast cell disorders: efficacy, safety, and practical considerations.

G. Passalacqua, A. Riccio, P. Bonadonna, 2013, The journal of allergy and clinical immunology. In practice.

Venom Immunotherapy in Patients with Clonal Mast CELL Disorders: Efficacy, Safety and Practical Considerations

G. Passalacqua, A. Riccio, P. Bonadonna, 2013 .

Venom immunotherapy in patients with mastocytosis

I. Alvarez-Twose, D. González-de-Olano, A. Vega-Castro, 2020, Allergo Journal.

Venom immunotherapy in patients with mastocytosis

I. Alvarez-Twose, D. González-de-Olano, A. Vega-Castro, 2020, Allergo Journal International.

Increased IL6 plasma levels in indolent systemic mastocytosis patients are associated with high risk of disease progression

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2016, Leukemia.

Indolent systemic mastocytosis without skin involvement vs. isolated bone marrow mastocytosis

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2011, Haematologica.

IgE‐mediated anaphylaxis to Hippobosca equina in a patient with systemic mastocytosis

I. Alvarez-Twose, A. Matito, L. Escribano, 2009, Allergy.

Flow cytometry criteria for systemic mastocytosis: bone marrow mast cell counts do not always count.

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2013, American journal of clinical pathology.

Clinical, Biological And Molecular Characteristics Of Mast Cell Activation Disorders: A Prospective Study In 62 Patients By The Spanish Network On Mastocytosis (REMA).

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2009 .

Mast Cell Activation Syndromes and Anaphylaxis: Multiple Diseases Part of the Same Spectrum.

I. Alvarez-Twose, A. Matito, D. González-de-Olano, 2019, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

COVID-19 infection in patients with mast cell disorders including mastocytosis does not impact mast cell activation symptoms

A. Órfão, C. Teodosio, P. Valent, 2021, The Journal of Allergy and Clinical Immunology: In Practice.

Dermoscopic features of skin lesions in patients with mastocytosis.

M. Plana, A. Órfão, P. Jaen, 2011, Archives of dermatology.

Spanish Society of Hematology and Hemotherapy expert consensus opinion for SARS-CoV-2 vaccination in onco-hematological patients

F. Bosch, P. Abrisqueta, J. Sancho, 2021, Leukemia & lymphoma.

Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis.

Toshiko Tanaka, S. Bandinelli, C. Gieger, 2021, American journal of human genetics.

Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas

A. Órfão, I. Alvarez-Twose, A. García-Montero, 2021, Frontiers in Oncology.

Amoxicillin-clavulanic acid-induced type II Kounis syndrome during general anaesthesia complicated with hypoxic-ischaemic encephalopathy.

I. Alvarez-Twose, N. Kounis, M. S. Sánchez Casado, 2020, Revista espanola de anestesiologia y reanimacion.

Amoxicillin-clavulanic acid-induced type II Kounis syndrome during general anaesthesia complicated with hypoxic-ischaemic encephalopathy.

I. Alvarez-Twose, N. Kounis, M. S. Sánchez Casado, 2019, Revista espanola de anestesiologia y reanimacion.

Management of Anesthesia in Adult and Pediatric Mastocytosis: A Study of the Spanish Network on Mastocytosis (REMA) Based on 726 Anesthetic Procedures

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2015, International Archives of Allergy and Immunology.

STAT3 and STAT5B Mutations in T/NK-Cell Chronic Lymphoproliferative Disorders of Large Granular Lymphocytes (LGL): Association with Disease Features

N. Villamor, Marcos González, A. Órfão, 2020, Cancers.

Anaphylactic Reactions with Three Non-Related Drugs (Gadoteridol, Paclitaxel, Bevacizumab) In a Patient with Severe Comorbidities.

I. Alvarez-Twose, M. A. Tejedor Alonso, M. D. Alonso-Diaz-de-Durana, 2021, Journal of investigational allergology & clinical immunology.

Clinical, biological, and molecular characteristics of clonal mast cell disorders presenting with systemic mast cell activation symptoms.

A. Órfão, C. Teodosio, B. de la Hoz, 2010, The Journal of allergy and clinical immunology.

KIT D816V-mutated bone marrow mesenchymal stem cells in indolent systemic mastocytosis are associated with disease progression.

A. Órfão, C. Teodosio, C. Caldas, 2015, Blood.

Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal

G. Nilsson, M. Triggiani, A. Órfão, 2021, HemaSphere.

Frequency and prognostic impact of KIT and other genetic variants in indolent systemic mastocytosis.

A. Órfão, C. Caldas, L. Sánchez-Muñoz, 2019, Blood.

Clinical impact of oncogenetic profiles in Systemic mastocytosis with an associated hematological non-mast cell disease. RUNNING TITLE: KIT mutation and AHNMD-associated genetic alterations in SM-AHNMD patients AUTHORS:

J. Esteve, E. Colado, A. Órfão, 2017 .

Management of adult mastocytosis

L. Sánchez-Muñoz, I. Alvarez-Twose, A. Matito, 2014 .

Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia

J. Merker, A. Órfão, J. Gotlib, 2016, Leukemia.

Bone Marrow Mast Cell Antibody-Targetable Cell Surface Protein Expression Profiles in Systemic Mastocytosis

A. Órfão, C. Teodosio, C. Caldas, 2019, International journal of molecular sciences.

Molecular Background, Clinical Features and Management of Pediatric Mastocytosis: Status 2021

P. Valent, K. Brockow, N. Irga-Jaworska, 2021, International journal of molecular sciences.

Fulminant necrotizing fasciitis caused by Serratia marcescens in an immunosuppressed host

P. Jaen, I. Alvarez-Twose, S. Vañó-Galván, 2014, International journal of dermatology.

Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children with mastocytosis

A. Órfão, P. Jaen, L. Schwartz, 2012, Allergy.

Complete response after imatinib mesylate therapy in a patient with well-differentiated systemic mastocytosis.

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2012, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Gene expression profile of highly purified bone marrow mast cells in systemic mastocytosis.

C. E. Pedreira, A. Órfão, C. Teodosio, 2013, The Journal of allergy and clinical immunology.

Clinical, immunophenotypic, and molecular characteristics of well-differentiated systemic mastocytosis.

A. Órfão, C. Teodosio, C. Caldas, 2016, The Journal of allergy and clinical immunology.

COVID-19 Vaccination in Mastocytosis: Recommendations of the European Competence Network on Mastocytosis (ECNM) and American Initiative in Mast Cell Diseases (AIM)

M. Triggiani, C. Bindslev‐Jensen, A. Órfão, 2021, The Journal of Allergy and Clinical Immunology: In Practice.

Risk and management of patients with mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) pandemic: Expert opinions

M. Triggiani, A. Órfão, H. Kluin-Nelemans, 2020, Journal of Allergy and Clinical Immunology.

Insights in Anaphylaxis and Clonal Mast Cell Disorders

I. Alvarez-Twose, D. González-de-Olano, 2017, Front. Immunol..

Detection of the KIT D816V mutation in peripheral blood of systemic mastocytosis: diagnostic implications

A. Órfão, C. Teodosio, C. Caldas, 2015, Modern Pathology.

Mastocytosis presenting with mast cell‐mediator release‐associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features

A. Órfão, L. Sánchez-Muñoz, I. Alvarez-Twose, 2022, Clinical and translational allergy.

Frequency of clonal mast cell diseases among patients presenting with anaphylaxis: A prospective study in 178 patients from 5 tertiary centers in Spain.

A. Órfão, A. Fiandor, I. Alvarez-Twose, 2019, The journal of allergy and clinical immunology. In practice.

Delving Into COVID-19 Vaccination-Induced Anaphylaxis: Are mRNA Vaccines Safe in Mast Cell Disorders?

I. Alvarez-Twose, T. Azenha Rama, Azenha Rama, 2021, Journal of investigational allergology & clinical immunology.

Efficacy of avapritinib versus best available therapy in the treatment of advanced systemic mastocytosis

S. Dimitrijević, D. DeAngelo, I. Galinsky, 2022, Leukemia.

Proposed ECNM-AIM Response Criteria in Advanced Systemic Mastocytosis.

M. Triggiani, A. Órfão, J. Lyons, 2022, The journal of allergy and clinical immunology. In practice.

Efficacy and safety of avapritinib in previously treated patients with advanced systemic mastocytosis

J. Panse, I. Dybedal, M. Deininger, 2022, Blood advances.

Ex vivo identification and characterization of a population of CD13high CD105+ CD45− mesenchymal stem cells in human bone marrow

A. Órfão, C. Teodosio, A. Amaral, 2015, Stem Cell Research & Therapy.

Interobserver variability in the classification of childhood maculopapular cutaneous mastocytosis

S. Greenberger, I. García-Doval, I. Alvarez-Twose, 2021, Journal of the European Academy of Dermatology and Venereology : JEADV.

Global Classification of Mast Cell Activation Disorders An ICD-10-CM-Adjusted Proposal of the ECNM-AIM Consortium.

M. Triggiani, A. Órfão, H. Kluin-Nelemans, 2022, The journal of allergy and clinical immunology. In practice.

KITD816V mutation in blood for the diagnostic screening of systemic mastocytosis and mast cell activation syndromes

A. Órfão, C. Caldas, L. Sánchez-Muñoz, 2022, Allergy.

Perioperative anaphylaxis in a patient with a solitary mastocytoma

I. Alvarez-Twose, A. Matito, A. Torrelo, 2019, Pediatric dermatology.

Flow cytometry in mastocytosis: utility as a diagnostic and prognostic tool.

A. Órfão, C. Teodosio, L. Sánchez-Muñoz, 2014, Immunology and allergy clinics of North America.

G. Nilsson, M. Triggiani, A. Órfão, 2016, The Journal of allergy and clinical immunology.

Mast Cell Diseases in Practice and Research: Issues and Perspectives Raised by Patients and Their Recommendations to the Scientific Community and Beyond.

M. Martín-Martínez, M. Triggiani, A. Órfão, 2022, The journal of allergy and clinical immunology. In practice.

Personalized Management Strategies in Mast Cell Disorders: ECNM-AIM User´s Guide for Daily Clinical Practice.

M. Triggiani, A. Órfão, T. George, 2022, The journal of allergy and clinical immunology. In practice.

Refined Treatment Response Criteria for Indolent Systemic Mastocytosis proposed by the ECNM-AIM Consortium.

M. Triggiani, A. Órfão, J. Lyons, 2022, The journal of allergy and clinical immunology. In practice.

Diagnosis and classification of mastocytosis in non‐specialized versus reference centres: a Spanish Network on Mastocytosis (REMA) study on 122 patients

A. Órfão, C. Caldas, L. Sánchez-Muñoz, 2016, British journal of haematology.

Nonaggressive systemic mastocytosis (SM) without skin lesions associated with insect-induced anaphylaxis shows unique features versus other indolent SM.

A. Órfão, P. Bonadonna, A. Zamó, 2014, The Journal of allergy and clinical immunology.