A. Horova

发表

Progress in Antidotes (Acetylcholinesterase Reactivators) Against Organophosphorus Pesticides

K. Kuča, D. Jun, K. Musílek, 2011 .

Preparation of 7-Methoxy Tacrine Dimer Analogs and Their In vitro/In silico Evaluation as Potential Cholinesterase Inhibitors

Dae Won Cho, K. Kuča, D. Jun, 2015 .

Preparation, in vitro evaluation and molecular modelling of pyridinium-quinolinium/isoquinolinium non-symmetrical bisquaternary cholinesterase inhibitors.

K. Kuča, D. Jun, K. Musílek, 2013, Bioorganic & medicinal chemistry letters.

Myasthenia Gravis – Current Treatment Standards and Emerging Drugs

K. Kuča, K. Musílek, O. Holas, 2012 .

Development of small bisquaternary cholinesterase inhibitors as drugs for pre-treatment of nerve agent poisonings

M. Valis, K. Kuča, E. Novotná, 2018, Drug design, development and therapy.

Tacrine-Trolox Hybrids: A Novel Class of Centrally Active, Nonhepatotoxic Multi-Target-Directed Ligands Exerting Anticholinesterase and Antioxidant Activities with Low In Vivo Toxicity.

K. Kuča, D. Jun, D. Maliňák, 2015, Journal of medicinal chemistry.

7-Methoxytacrine-Adamantylamine Heterodimers as Cholinesterase Inhibitors in Alzheimer’s Disease Treatment — Synthesis, Biological Evaluation and Molecular Modeling Studies

K. Kuča, K. Musílek, O. Soukup, 2013, Molecules.

Preparation, in vitro screening and molecular modelling of symmetrical bis-quinolinium cholinesterase inhibitors--implications for early myasthenia gravis treatment.

Kamil Kuca, Frank Gunn-Moore, Vlastimil Dohnal, 2011, Bioorganic & medicinal chemistry letters.

A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K305, K307) with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

K. Musílek, J. Kassa, A. Horova, 2017 .

Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.

V. Dohnal, K. Kuča, F. Gunn-Moore, 2011, Bioorganic & medicinal chemistry.

Design, synthesis and in vitro testing of 7-methoxytacrine-amantadine analogues: a novel cholinesterase inhibitors for the treatment of Alzheimer’s disease

K. Kuča, D. Jun, K. Musílek, 2015, Medicinal Chemistry Research.

7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer’s Disease Treatment

K. Kuča, D. Jun, D. Maliňák, 2015, Molecules.

7-MEOTA-donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies.

K. Kuča, D. Řípová, E. Hrubá, 2014, European journal of medicinal chemistry.

A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K920, K923) with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

K. Musílek, J. Kassa, A. Horova, 2015 .

A Comparison of the Reactivating and Therapeutic Efficacy of Two Newly Developed Oximes (K727 and K733) with Oxime K203 and Trimedoxime in Tabun‐Poisoned Rats and Mice

K. Musílek, J. Kassa, A. Horova, 2015, Basic & clinical pharmacology & toxicology.

A comparison of the reactivating and therapeutic efficacy of two novel bispyridinium oximes (K727, K733) with the oxime HI-6 and obidoxime in sarin-poisoned rats and mice

K. Musílek, J. Kassa, A. Horova, 2015, Toxicology mechanisms and methods.

The evaluation of the reactivating and therapeutic efficacy of two novel oximes (K361 and K378) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

K. Musílek, J. Kassa, A. Horova, 2014, Toxicology mechanisms and methods.

The evaluation of the reactivating and therapeutic efficacy of three novel bispyridinium oximes (K454, K456, K458) in comparison with the oxime K203 and trimedoxime in tabun-poisoned rats and mice

K. Musílek, J. Kassa, A. Horova, 2013, Toxicology mechanisms and methods.

Synthesis and in vitro evaluation of 7-methoxy-N-(pent-4-enyl)-1,2,3,4-tetrahydroacridin-9-amine-new tacrine derivate with cholinergic properties.

K. Kuča, K. Musílek, Z. Fišar, 2011, Bioorganic & medicinal chemistry letters.

Preparation, in vitro screening and molecular modelling of monoquaternary compounds related to the selective acetylcholinesterase inhibitor BW284c51.

V. Dohnal, K. Kuča, K. Musílek, 2014, Medicinal chemistry (Shariqah (United Arab Emirates)).