Yao Dai

发表

Structure-based Design Targeted at LOX-1, a Receptor for Oxidized Low-Density Lipoprotein

J. Mehta, S. Thakkar, M. Khaidakov, 2015, Scientific Reports.

LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis.

Yubo Fan, J. Mehta, Xiaoyan Deng, 2014, Cardiovascular research.

High Fat Diet Causes Renal Fibrosis in LDLr-null Mice Through MAPK-NF-&kgr;B Pathway Mediated by Ox-LDL

J. Mehta, Xianwei Wang, P. Palade, 2014, Journal of cardiovascular pharmacology.

Natural IAP inhibitor Embelin enhances therapeutic efficacy of ionizing radiation in prostate cancer.

T. Lawrence, Liang Xu, Yao Dai, 2011, American journal of cancer research.

Development of optimized AAV3 serotype vectors: Mechanism of high-efficiency transduction of human liver cancer cells

Morag Park, P. Stacpoole, A. Srivastava, 2011, Gene Therapy.

MicroRNA-29, a mysterious regulator in myocardial fibrosis and circulating miR-29a as a biomarker.

J. Mehta, Yao Dai, Dongsheng Dai, 2014, Journal of the American College of Cardiology.

Celastrol potentiates radiotherapy by impairment of DNA damage processing in human prostate cancer.

T. Lawrence, M. Ljungman, Liang Xu, 2009, International journal of radiation oncology, biology, physics.

Molecularly Targeted Radiosensitization of Human Prostate Cancer by Modulating Inhibitor of Apoptosis

K. Pienta, T. Lawrence, Mary A Davis, 2008, Clinical Cancer Research.

Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa

K. Pienta, T. Lawrence, Meilan Liu, 2008, Molecular Cancer Therapeutics.

Celastrol potentiates radiation therapy via impairment of DNA damage processing in human prostate cancer

T. Lawrence, M. Ljungman, Yao Dai, 2009 .

c-Src is required for hypoxia-induced metastasis-associated functions in prostate cancer cells

Yao Dai, D. Siemann, 2019, OncoTargets and therapy.

Regulation of autophagy and apoptosis in response to angiotensin II in HL-1 cardiomyocytes.

J. Mehta, M. Khaidakov, Xianwei Wang, 2013, Biochemical and biophysical research communications.

LOX-1, oxidant stress, mtDNA damage, autophagy, and immune response in atherosclerosis.

J. Mehta, F. Romeo, M. Khaidakov, 2014, Canadian journal of physiology and pharmacology.

Cross-Talk Between PCSK9 and Damaged mtDNA in Vascular Smooth Muscle Cells: Role in Apoptosis.

J. Mehta, Xiaoyan Deng, Xianwei Wang, 2016, Antioxidants & redox signaling.

Unbiased RNA-Seq-driven identification and validation of reference genes for quantitative RT-PCR analyses of pooled cancer exosomes

J. Köhler, Aiping Lu, Haiyun Wang, 2020, BMC genomics.

LOX-1, a bridge between GLP-1R and mitochondrial ROS generation in human vascular smooth muscle cells.

J. Mehta, Xianwei Wang, Yao Dai, 2013, Biochemical and biophysical research communications.

Novel Functions of Endothelial Scavenger Receptor Class B Type I

C. Mineo, Yao Dai, Liming Yu, 2021, Current Atherosclerosis Reports.

Modulation of myocardial injury and collagen deposition following ischaemia-reperfusion by linagliptin and liraglutide, and both together.

J. Mehta, Xianwei Wang, Sharda P. Singh, 2016, Clinical science.

Glucagon-like Peptide-1 Receptor Agonist Liraglutide Inhibits Endothelin-1 in Endothelial Cell by Repressing Nuclear Factor-Kappa B Activation

J. Mehta, Mingwei Chen, Yao Dai, 2013, Cardiovascular Drugs and Therapy.

Prevention of export of anoxia/reoxygenation injury from ischemic to nonischemic cardiomyocytes via inhibition of endocytosis.

J. Mehta, T. Sawamura, F. Romeo, 2014, American journal of physiology. Heart and circulatory physiology.

Regulation of MSR-1 and CD36 in macrophages by LOX-1 mediated through PPAR-γ.

J. Mehta, Xianwei Wang, Mingwei Chen, 2013, Biochemical and biophysical research communications.

Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis

J. Mehta, M. Khaidakov, Xianwei Wang, 2013, Scientific Reports.

DPP-4 Inhibitors Repress NLRP3 Inflammasome and Interleukin-1beta via GLP-1 Receptor in Macrophages Through Protein Kinase C Pathway

J. Mehta, Xianwei Wang, Yao Dai, 2014, Cardiovascular Drugs and Therapy.

GLP-1 Agonists Inhibit ox-LDL Uptake in Macrophages by Activating Protein Kinase A

J. Mehta, Xianwei Wang, Yao Dai, 2014, Journal of cardiovascular pharmacology.

E-cadherin plasticity in prostate cancer stem cell invasion.

J. Vieweg, Yao Dai, D. Siemann, 2011, American journal of cancer research.

DPP-4 inhibitors repress foam cell formation by inhibiting scavenger receptors through protein kinase C pathway

J. Mehta, Xianwei Wang, Yao Dai, 2013, Acta Diabetologica.

Can autologous bone marrow transplantation improve systolic function in patients with multiple myeloma related cardiac amyloidosis?

B. Barlogie, J. Mehta, S. Vallurupalli, 2014, International journal of cardiology.

Unbiased RNA-Seq-driven identification and validation of reference 1 genes for quantitative RT-PCR analyses of cancer exosomes 2

J. Köhler, Yao Dai, Wang, 2020 .

Degradation of heparan sulfate proteoglycans enhances oxidized-LDL-mediated autophagy and apoptosis in human endothelial cells.

J. Mehta, M. Khaidakov, Xianwei Wang, 2012, Biochemical and biophysical research communications.

MicroRNA-98 regulates foam cell formation and lipid accumulation through repression of LOX-1

J. Mehta, Jun Li, Xiao-qin Wu, 2018, Redox biology.

ischemic cardiomyocytes via inhibition of endocytosis

J. Mehta, T. Sawamura, F. Romeo, 2014 .

Targeting mTOR Complex 2 in Castration-Resistant Prostate Cancer with Acquired Docetaxel Resistance

Meijia Wu, Dongsheng Hong, Qingwei Zhao, 2022, Drug design, development and therapy.

Targeting mTOR Complex 2 in Castration-Resistant Prostate Cancer with Acquired Docetaxel Resistance

Meijia Wu, Dongsheng Hong, Qingwei Zhao, 2022 .

Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB

Liang Xu, Yang Meng, T. Lawrence, 2010, PloS one.

Impact of hypoxia on the metastatic potential of human prostate cancer cells.

Yao Dai, D. Siemann, K. Bae, 2011, International journal of radiation oncology, biology, physics.

Lectin-like Oxidized Low-density Lipoprotein Receptor-1 (LOX-1) and Cardiac Fibroblast Growth

J. Mehta, M. Khaidakov, Sona Mitra, 2012, Hypertension.

Hypoxia regulates SOX2 expression to promote prostate cancer cell invasion and sphere formation.

J. Vieweg, Yao Dai, D. Siemann, 2016, American journal of cancer research.

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes

Ruth Nussinov, Feixiong Cheng, Junfei Zhao, 2020, PLoS Comput. Biol..

c‐Fos separation from Lamin A/C by GDF15 promotes colon cancer invasion and metastasis in inflammatory microenvironment

Zhou Zhou, Li Zhao, Yao Dai, 2020, Journal of cellular physiology.

An integrative pharmacogenomics analysis identifies therapeutic targets in KRAS-mutant lung cancer

P. Jänne, J. Köhler, Haiyun Wang, 2019, EBioMedicine.

Emerging role of microRNAs in regulating macrophage activation and polarization in immune response and inflammation

Cheng Huang, Xiao-ming Meng, Jun Li, 2016, Immunology.

Review Article Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor- kappa B

T. Lawrence, Liang Xu, Yao Dai, 2009 .

Overcoming cancer therapy resistance by targeting inhibitors of apoptosis proteins and nuclear factor-kappa B.

T. Lawrence, Liang Xu, Yao Dai, 2009, American journal of translational research.

Impact of Tumor Hypoxia, Src, and Met Signaling in the Dissemination of Tumor Cells

W. Shi, Yao Dai, D. Siemann, 2011 .

Hypoxia, Metastasis, and Antiangiogenic Therapies

M. Horsman, Yao Dai, D. Siemann, 2014 .

Role of exosomal small RNA in prostate cancer metastasis

Xiaoyi Huang, Liang Wang, Yanqiao Zhang, 2018, Cancer management and research.

BMS-777607, a Small-Molecule Met Kinase Inhibitor, Suppresses Hepatocyte Growth Factor–Stimulated Prostate Cancer Metastatic Phenotype In vitro

Yao Dai, D. Siemann, 2010, Molecular Cancer Therapeutics.

A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB

T. Lawrence, Meilan Liu, Liang Xu, 2009, BMC Cancer.

Establishment and characterization of a docetaxel-resistant human prostate cancer cell line

Qingwei Zhao, Jian Liu, Lihua Wu, 2020, Oncology letters.

Therapeutic Response-Based Reclassification of Multiple Tumor Subtypes Reveals Intrinsic Molecular Concordance of Therapy Across Histologically Disparate Cancers

J. Köhler, Haiyun Wang, Fan Zhang, 2021, Frontiers in Cell and Developmental Biology.

Drug-driven reclassification of multiple tumour subtypes reveals intrinsic molecular concordance of therapy across histologically disparate cancers

J. Köhler, Haiyun Wang, Fan Zhang, 2021, bioRxiv.

Impact of Hepatitis C Seropositivity on the Risk of Coronary Heart Disease Events

J. Mehta, C. Hagedorn, R. Delongchamp, 2014, The American journal of cardiology.

Eptifibatide-Induced Thrombocytopenia--When Inhibitor Turns Killer.

Yao Dai, A. Deshmukh, Zufeng Ding, 2016, American journal of therapeutics.

Regulation of autophagy and apoptosis in response to ox-LDL in vascular smooth muscle cells, and the modulatory effects of the microRNA hsa-let-7 g.

J. Mehta, M. Khaidakov, Xianwei Wang, 2013, International journal of cardiology.

Abstract B59: Dual mTOR kinase inhibitor reverses rapamycin resistance in prostate cancer cells

Li Zhao, Yao Dai, D. Siemann, 2015 .

Xanthine Oxidase Induces Foam Cell Formation through LOX-1 and NLRP3 Activation

J. Mehta, S. Vallurupalli, Yao Dai, 2017, Cardiovascular Drugs and Therapy.

Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607

Yao Dai, D. Siemann, 2012, BMC Cancer.

Scavenger receptors and non-coding RNAs: relevance in atherogenesis.

J. Mehta, G. Condorelli, Yao Dai, 2016, Cardiovascular research.

Constitutively active c-Met kinase in PC-3 cells is autocrine-independent and can be blocked by the Met kinase inhibitor BMS-777607

Yao Dai, D. Siemann, 2012, BMC Cancer.

Impact of the small molecule Met inhibitor BMS-777607 on the metastatic process in a rodent tumor model with constitutive c-Met activation

Yao Dai, D. Siemann, K. Bae, 2012, Clinical & Experimental Metastasis.

Enhancing Cancer Driver Gene Prediction by Protein-Protein Interaction Network

K. Yu, Zi-Ke Zhang, Chuang Liu, 2021, IEEE/ACM Transactions on Computational Biology and Bioinformatics.

Impact of the small molecule Met inhibitor BMS-777607 on the metastatic process in a rodent tumor model with constitutive c-Met activation

Yao Dai, D. Siemann, K. Bae, 2012, Clinical & Experimental Metastasis.

MicroRNAs Involved in the Regulation of Postischemic Cardiac Fibrosis

J. Mehta, M. Khaidakov, Xianwei Wang, 2013, Hypertension.

LOX-1 in the maintenance of cytoskeleton and proliferation in senescent cardiac fibroblasts.

J. Mehta, M. Khaidakov, Xianwei Wang, 2013, Journal of molecular and cellular cardiology.

Fcirc: A comprehensive pipeline for the exploration of fusion linear and circular RNAs

Jie Zheng, Yao Dai, Haiyun Wang, 2020, GigaScience.

MiR-590-5p Inhibits Oxidized- LDL Induced Angiogenesis by Targeting LOX-1

J. Mehta, Jun Li, Yao Dai, 2016, Scientific Reports.

Lectin-Like ox-LDL Receptor-1 (LOX-1)–Toll-Like Receptor 4 (TLR4) Interaction and Autophagy in CATH.a Differentiated Cells Exposed to Angiotensin II

J. Mehta, M. Khaidakov, Xianwei Wang, 2015, Molecular Neurobiology.

Molecularly Targeted Radiosensitization of Human Prostate Cancer by Modulating Inhibitor of Apoptosis

K. Pienta, T. Lawrence, Mary A Davis, 2008, Clinical Cancer Research.

Inflammasomes and Atherosclerosis

J. Mehta, S. Vallurupalli, Yao Dai, 2016 .

Another road leads to HIF-1 activation: implications for prostate cancer progression.

Yao Dai, D. Siemann, K. Bae, 2012, Asian journal of andrology.