P. Erskine

发表

Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium.

J. Cooper, Jingxu Guo, A. Coker, 2017, Acta crystallographica. Section F, Structural biology communications.

X-ray, neutron and NMR studies of the catalytic mechanism of aspartic proteinases

Leighton Coates, Steve P. Wood, Peter T. Erskine, 2006, European Biophysics Journal.

The catalytic mechanism of an aspartic proteinase explored with neutron and X-ray diffraction.

Jon Cooper, Leighton Coates, Andrey Kovalevsky, 2008, Journal of the American Chemical Society.

A neutron Laue diffraction study of endothiapepsin: implications for the aspartic proteinase mechanism.

J. Cooper, S. Wood, L. Coates, 2001, Biochemistry.

Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Arabidopsis thaliana.

J. Cooper, S. Wood, R. Gill, 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization of 5‐aminolaevulinic acid dehydratase from Escherichia coli and Saccharomyces cerevisiae and preliminary X‐ray characterization of the crystals

J. Cooper, S. Wood, P. Thomas, 1997, Protein science : a publication of the Protein Society.

Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.

Jonathan D. Wilden, S. Wells, J. Cooper, 2018, Acta crystallographica. Section D, Structural biology.

X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure–function studies of a neuronal calcium-signalling protein

S. Wells, J. Cooper, B. Wallace, 2015 .

X-ray structure of a putative reaction intermediate of 5-aminolaevulinic acid dehydratase.

J. Cooper, S. Wood, L. Coates, 2003, The Biochemical journal.

Structure of Chlorobium vibrioforme 5-aminolaevulinic acid dehydratase complexed with a diacid inhibitor.

J. Cooper, S. Wood, L. Coates, 2005, Acta crystallographica. Section D, Biological crystallography.

MAD analyses of yeast 5-aminolaevulinate dehydratase: their use in structure determination and in defining the metal-binding sites.

J. Cooper, I. Tickle, M. Warren, 2000, Acta crystallographica. Section D, Biological crystallography.

5-Aminolaevulinic acid dehydratase

J. Cooper, P. Erskine, 2002 .

The X‐ray structure of yeast 5‐aminolaevulinic acid dehydratase complexed with two diacid inhibitors

J. Cooper, S. Wood, L. Coates, 2001, FEBS letters.

The schiff base complex of yeast 5‐aminolaevulinic acid dehydratase with laevulinic acid

J. Cooper, A. Coker, S. Wood, 2000, Protein science : a publication of the Protein Society.

X-ray structure of 5-aminolevulinic acid dehydratase from Escherichia coli complexed with the inhibitor levulinic acid at 2.0 A resolution.

J. Cooper, A. Coker, S. Wood, 1999, Biochemistry.

Crystallization and preliminary X-ray diffraction analysis of calexcitin from Loligo pealei: a neuronal protein implicated in learning and memory.

J. Cooper, S. Wood, K. Giese, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Five atomic resolution structures of endothiapepsin inhibitor complexes: implications for the aspartic proteinase mechanism.

J. Cooper, S. Wood, L. Coates, 2002, Journal of molecular biology.

Biological Crystallography High-resolution Structure of Myo-inositol Monophosphatase, the Putative Target of Lithium Therapy

Leighton Coates, Michael Gore, Darren Thompson, 2022 .

Crystallization and preliminary X-ray diffraction analysis of L-threonine dehydrogenase (TDH) from the hyperthermophilic archaeon Thermococcus kodakaraensis.

J. Cooper, Q. Bashir, A. Coker, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of the 2,4′-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP

J. Cooper, S. Wood, R. Keegan, 2014, Acta crystallographica. Section D, Biological crystallography.

Structure of a Kunitz-type potato cathepsin D inhibitor.

J. Cooper, Jingxu Guo, A. Coker, 2015, Journal of structural biology.

The 1.6A X-ray structure of the unusual c-type cytochrome, cytochrome cL, from the methylotrophic bacterium Methylobacterium extorquens.

J. Cooper, C. Anthony, D. Bourgeois, 2006, Journal of molecular biology.

5-Aminolaevulinic Acid Dehydratase, Porphobilinogen Deaminase and Uroporphyrinogen III Synthase

J. Cooper, H. Schubert, P. Erskine, 2009 .

The atomic resolution structure of methanol dehydrogenase from Methylobacterium extorquens.

J. Cooper, C. Anthony, A. Coker, 2004, Acta crystallographica. Section D, Biological crystallography.

Crystallization and preliminary X-ray characterization of the tetrapyrrole-biosynthetic enzyme porphobilinogen deaminase from Bacillus megaterium

J. Cooper, S. Wood, M. Akhtar, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structure of yeast 5-aminolaevulinic acid dehydratase complexed with the inhibitor 5-hydroxylaevulinic acid.

J. Cooper, A. Coker, S. Wood, 2005, Acta crystallographica. Section D, Biological crystallography.

Binding of Gd(3+) to the neuronal signalling protein calexcitin identifies an exchangeable Ca(2+)-binding site.

J. Cooper, Jingxu Guo, A. Coker, 2016, Acta crystallographica. Section F, Structural biology communications.

Atomic resolution analysis of the catalytic site of an aspartic proteinase and an unexpected mode of binding by short peptides

J. Cooper, S. Wood, L. Coates, 2003, Protein science : a publication of the Protein Society.

The x-ray structure of yeast 5-aminolaevulinic acid dehydratase complexed with substrate and three inhibitors.

J. Cooper, S. Wood, M. Warren, 2001, Journal of molecular biology.

Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans, Escherichia coli and the hyperthermophile Pyrobaculum calidifontis.

J. Cooper, Jingxu Guo, A. Coker, 2017, Acta crystallographica. Section D, Structural biology.

X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolase

J. Cooper, S. Wood, P. Thomas, 1997, Nature Structural Biology.

The 1.1 Å resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.

Leighton Coates, Ronan Keegan, David G Waterman, 2016, Acta crystallographica. Section D, Structural biology.

Structure of the neuronal protein calexcitin suggests a mode of interaction in signalling pathways of learning and memory.

J. Cooper, S. Wood, K. Giese, 2006, Journal of molecular biology.

Exploring the Mechanism of β-Lactam Ring Protonation in the Class A β-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography.

J. Cooper, K. Weiss, L. Coates, 2016, Journal of medicinal chemistry.

A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor†

J. Cooper, E. Mitchell, S. Coker, 2010, Biochemistry.

X‐ray structure analysis of an engineered Fe‐superoxide dismutase Gly‐Ala mutant with significantly reduced stability to denaturant

J. Cooper, S. Wood, D. Young, 1996, FEBS letters.

Crystallization and preliminary X-ray diffraction analysis of the protease from Southampton norovirus complexed with a Michael acceptor inhibitor.

J. Cooper, S. Coker, S. Wood, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

High resolution structure of BipD: an invasion protein associated with the type III secretion system of Burkholderia pseudomallei.

J. Cooper, S. Wood, G. Fox, 2006, Journal of molecular biology.

Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution

J. Cooper, A. Coker, S. Wood, 2014, Acta crystallographica. Section D, Biological crystallography.

Insights into the mechanism of pyrrole polymerization catalysed by porphobilinogen deaminase: high-resolution X-ray studies of the Arabidopsis thaliana enzyme.

J. Cooper, S. Wood, R. Gill, 2013, Acta crystallographica. Section D, Biological crystallography.

The X-ray structure of the plant like 5-aminolaevulinic acid dehydratase from Chlorobium vibrioforme complexed with the inhibitor laevulinic acid at 2.6 A resolution.

J. Cooper, S. Wood, L. Coates, 2004, Journal of molecular biology.

An analysis of subdomain orientation, conformational change and disorder in relation to crystal packing of aspartic proteinases.

J. Cooper, E. Carpenter, T. Blundell, 2012, Acta crystallographica. Section D, Biological crystallography.

Preliminary neutron and ultrahigh-resolution X-ray diffraction studies of the aspartic proteinase endothiapepsin cocrystallized with a gem-diol inhibitor.

J. Cooper, P. Langan, Han-Fang Tuan, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

The structure of endothiapepsin complexed with the gem-diol inhibitor PD-135,040 at 1.37 A.

J. Cooper, S. Wood, L. Coates, 2003, Acta crystallographica. Section D, Biological crystallography.

Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei.

J. Cooper, S. Wood, R. Gill, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization and preliminary X-ray diffraction analysis of BipD, a virulence factor from Burkholderia pseudomallei

J. Cooper, S. Wood, R. Gill, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

The catalytic mechanism of an aspartic proteinase explored with neutron and X-ray diffraction.

J. Cooper, M. Mustyakimov, Han-Fang Tuan, 2008, Journal of the American Chemical Society.

X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein.

Alexander S. Fokas, R. Hagan, H. Rehman, 2015, Acta crystallographica. Section D, Biological crystallography.

A. Coker, P. Erskine, E. Deery, 2014, Acta crystallographica. Section D, Biological crystallography.

A Structural Study of Norovirus 3C Protease Specificity: Binding of a Designed Active Site-Directed Peptide Inhibitor

J. Cooper, E. Mitchell, S. Coker, 2010, Biochemistry.