C. Garbay

发表

Role of water molecules for binding inhibitors in the SH2 domain of Grb2: A molecular dynamics study

B. Maigret, N. Gresh, V. Leroux, 2007 .

Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening.

Sylvain Rault, Maria A Miteva, Bruno O Villoutreix, 2011, Chemistry & biology.

Identification of Aurora Kinases as RasGAP Src Homology 3 Domain-binding Proteins*

J. Camonis, C. Garbay, S. L'hoste, 2002, The Journal of Biological Chemistry.

Synthesis of aryl phosphates based on pyrimidine and triazine scaffolds.

N. Gresh, J. Florent, C. Lenoir, 2010, European journal of medicinal chemistry.

Design, Synthesis, and Biological Evaluation of the First Podophyllotoxin Analogues as Potential Vascular‐Disrupting Agents

M. Vidal, C. Lenoir, C. Garbay, 2010, ChemMedChem.

Insights into the interaction of high potency inhibitor IRC‐083864 with phosphatase CDC25

M. Sari, M. Miteva, G. Bertho, 2017, Proteins.

Design and synthesis of novel bis-thiazolone derivatives as micromolar CDC25 phosphatase inhibitors: effect of dimerisation on phosphatase inhibition.

B. Villoutreix, M. Miteva, C. Garbay, 2012, Bioorganic & medicinal chemistry letters.

Preparation and evaluation of a set of bis(methoxycarbonylmethylthio) heteroquinones as CDC25B phosphatase inhibitors

T. Besset, C. Garbay, C. Morin, 2011 .

Development of Novel Thiazolopyrimidines as CDC25B Phosphatase Inhibitors

B. Villoutreix, B. Ducommun, O. Mondésert, 2009, ChemMedChem.

Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.

B. Roques, M. Vidal, I. Broutin, 2002, Journal of molecular biology.

Depletion of the novel protein PHACTR-1 from human endothelial cells abolishes tube formation and induces cell death receptor apoptosis.

J. Larghero, C. Garbay, Y. Lepelletier, 2011, Biochimie.

Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis development.

O. Hermine, Wang-Qing Liu, C. Garbay, 2015, Biochimie.

Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain.

B. Roques, N. Gresh, M. Vidal, 1999, Journal of medicinal chemistry.

Inhibitors of Ras signal transduction as antitumor agents.

B. Roques, M. Vidal, C. Garbay, 2000, Biochemical pharmacology.

Development of a chemiluminescent screening assay for detection of vascular endothelial growth factor receptor 1 ligands.

M. Vidal, C. Garbay, V. Goncalves, 2007, Analytical biochemistry.

Structure‐based design of a bicyclic peptide antagonist of the vascular endothelial growth factor receptors

M. Vidal, C. Garbay, V. Goncalves, 2008, Journal of peptide science : an official publication of the European Peptide Society.

Biochemical and structural analysis of the binding determinants of a vascular endothelial growth factor receptor peptidic antagonist.

M. Vidal, C. Lenoir, R. Fattorusso, 2010, Journal of medicinal chemistry.

Total chemical synthesis of the D2 domain of human VEGF receptor 1

M. Vidal, C. Garbay, V. Goncalves, 2009, Journal of peptide science : an official publication of the European Peptide Society.

RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance.

J. Herbeuval, C. Garbay, Y. Lepelletier, 2010, Cellular signalling.

New Peptides Structurally Related to VEGF-A165 Exon-7 and -8 Encoded Domains Antagonize Its Binding to NRP-1 and VEGF-R1

O. Hermine, Wang-Qing Liu, C. Garbay, 2015, International Journal of Peptide Research and Therapeutics.

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model.

M. Montès, J. Boucher, O. Hermine, 2014, Cancer letters.

Structure-activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs.

M. Vidal, C. Lenoir, Wang-Qing Liu, 2004, Journal of medicinal chemistry.

On-resin cyclization of peptide ligands of the Vascular Endothelial Growth Factor Receptor 1 by copper(I)-catalyzed 1,3-dipolar azide-alkyne cycloaddition.

P. Coric, M. Vidal, S. Bouaziz, 2007, Bioorganic & medicinal chemistry letters.

Design, Synthesis, and Biological Evaluation of Covalent Inhibitors of Focal Adhesion Kinase (FAK) against Human Malignant Glioblastoma.

X. Coumoul, D. Lietha, Yongliang Li, 2020, Journal of medicinal chemistry.

Geometry of the antitumor drug ditercalinium bisintercalated into d(CpGpCpG)2 by 1H NMR.

M. Delepierre, B. Roques, J. Le Pecq, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Theoretical design, chemical synthesis and footprinting analysis of a novel peptide derivative of the intercalator 7-H pyridocarbazole targeted towards the major groove of DNA.

B. Roques, N. Gresh, C. Garbay, 1994, Journal of biomolecular structure & dynamics.

Grb2 promotes reinitiation of meiosis in Xenopus oocytes.

K. Cailliau, A. Ducruix, E. Browaeys-Poly, 2001, Cellular signalling.

Development of Binding Assays for the SH2 Domain of Grb7 and Grb2 Using Fluorescence Polarization

B. Gril, M. Vidal, A. Burnol, 2008, Journal of biomolecular screening.

Novel CCK-B receptor agonists: diketopiperazine analogues derived from CCK4 bioactive conformation

B. Roques, A. Bado, C. Garbay, 1996, Regulatory Peptides.

STAT3-Stathmin Interactions Control Microtubule Dynamics

N. Verma, Y. Volkov, A. Davies, 2009 .

The cytotoxicity of a Grb2-SH3 inhibitor in Bcr-Abl positive K562 cells.

Qiang Chen, M. Vidal, Wang-Qing Liu, 2008, Biochemical pharmacology.

Affinity chromatography for purification of the modular protein growth factor receptor-bound protein 2 and development of a screening test for growth factor receptor-bound protein 2 Src homology 3 domain inhibitor using peroxidase-linked ligand.

B. Gril, M. Vidal, C. Lenoir, 2006, Analytical biochemistry.

Low concentrations of acridine dimers inhibit micrococcus AP endonuclease through interaction with apurinic sites in DNA.

B. Roques, J. Markovits, C. Malvy, 1990, Chemico-biological interactions.

Inhibition of the ras-dependent mitogenic pathway by phosphopeptide prodrugs with antiproliferative properties.

M. Vidal, C. Garbay, C. Périgaud, 2000, Bioorganic & medicinal chemistry letters.

Solution structure of the N-terminal SH3 domain of Grb2 by 1H NMR and identification of its ligand binding region

B. Roques, B. Tocqué, C. Garbay, 1995 .

Inhibitors of tyrosine kinase proteins induced Ras signaling pathway as potential anti-tumor agents

B. Gril, M. Vidal, C. Lenoir, 2005 .

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

N. Gresh, M. Vidal, C. Lenoir, 2004, Biochemistry.

Implication of protein S thrombin-sensitive region with membrane binding via conformational changes in the gamma-carboxyglutamic acid-rich domain.

M. Aiach, P. Gaussem, C. Garbay, 2001, The Biochemical journal.

Efficient synthesis of N-benzyl-3-aminopyrrolidine-2,5-dione and N-benzyl-3-aminopyrrolidin-2-one

H. Galons, C. Garbay, M. Vidal, 2004 .

Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells.

B. Roques, B. Ducos, H. Meudal, 1997, Journal of medicinal chemistry.

Microwave-assisted synthesis of 2,5-disubstituted pyrimidine derivatives via Buchwald-Hartwig amination

C. Garbay, M. Ethève-Quelquejeu, Huixiong Chen, 2020 .

A very short route to enantiomerically pure coumarin-bearing fluorescent amino acids.

C. Garbay, L. Bischoff, Marie-Priscille Brun, 2004, Angewandte Chemie.

Rational design, structure, and biological evaluation of cyclic peptides mimicking the vascular endothelial growth factor.

Michel Vidal, Christiane Garbay, P. Coric, 2007, Journal of medicinal chemistry.

An Efficient and Enantioselective Synthesis of Suitably Protected β‐[1‐(4‐Malonyl)naphthyl]‐L‐alanine and β‐[1‐(4‐Malonylmethyl)naphthyl]‐L‐alanine: Novel Fluorescent and Non‐Hydrolysable Phosphotyrosine Mimetics

N. Gresh, C. Garbay, Huixiong Chen, 2006 .

Terminal alkyne-functionalized triazine by Sonogashira coupling: synthesis of a potential cell signalling inhibitor via click chemistry

N. Gresh, J. Florent, C. Garbay, 2008 .

Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties.

N. Gresh, B. Ducommun, O. Mondésert, 2008, Bioorganic & medicinal chemistry.

High yielding microwave-assisted synthesis of tri-substituted 1,3,5-triazines using Pd-catalyzed aryl and heteroarylamination

C. Garbay, P. Dao, Huixiong Chen, 2012 .

Novel 1,4-benzodiazepine derivatives with antiproliferative properties on tumor cell lines.

N. Gresh, Wang-Qing Liu, C. Garbay, 2007, Bioorganic & medicinal chemistry letters.

Synthetic route to dinuclear platinum(II) complexes [{trans-PtCl(NH3)2}2(mu-L)]2+ (L = aliphatic or heterocyclic diamine) as potential antitumor agents, exploiting the mutual activation of hydroxido ligands and ammonium groups.

S. Rizzato, C. Lenoir, A. Albinati, 2008, Inorganic chemistry.

The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix

J. Sussman, I. Silman, M. Harel, 2013 .

New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitors.

Wang-Qing Liu, C. Garbay, B. Valentin, 2007, Bioorganic & medicinal chemistry letters.

Rapid discovery of triazolobenzylidene-thiazolopyrimidines (TBTP) as CDC25 phosphatase inhibitors by parallel click chemistry and in situ screening.

C. Garbay, Emmanuelle Braud, S. Kolb, 2009, Journal of combinatorial chemistry.

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity.

M. Montès, N. Gresh, M. Miteva, 2005, Bioorganic & medicinal chemistry.

Development of new potent agonists able to interact with two postulated subsites of the cholecystokinin CCK-B receptor

B. Roques, F. Noble, C. Garbay, 1997, Letters in Peptide Science.

New CCK2 agonists confirming the heterogeneity of CCK2 receptors: characterisation of BBL454

A. Bado, F. Beslot, C. Garbay, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Synthesis and biological characterisation of [3H]BBL454, a new CCK2 selective radiolabelled agonist displaying original pharmacological properties.

C. Garbay, R. Genet, B. Bellier, 2004, Bioorganic & medicinal chemistry letters.

How a single inversion of configuration leads to a reversal of the binding mode: proposal of a novel arrangement of CCK2 ligands in their receptor, and contribution to the development of peptidomimetic or non-peptide CCK2 ligands.

C. Garbay, B. Bellier, 2003, European journal of medicinal chemistry.

Computer modelling of new pseudopeptide CCK2 agonists

B. Maigret, A. Cartier, C. Garbay, 2002 .

Replacement of glycine with dicarbonyl and related moieties in analogues of the C-terminal pentapeptide of cholecystokinin: CCK(2) agonists displaying a novel binding mode.

B. Maigret, H. Meudal, C. Garbay, 2000, Journal of medicinal chemistry.

Involvement of D2 dopamine receptors in the opposing effects of two CCK-B agonists in a spatial recognition memory task: role of the anterior nucleus accumbens

C. Garbay, H. Dhôtel, I. Léna, 2000, Psychopharmacology.

The CholecystokininB Receptor Is Coupled to Two Effector Pathways Through Pertussis Toxin‐Sensitive and ‐Insensitive G Proteins

F Noble, B. Roques, F. Noble, 1999, Journal of neurochemistry.

Opposite effects of CCKB agonists in grooming behaviour in rats: further evidence for two CCKB subsites

B. Roques, C. Garbay, N. Ladurelle, 1998 .

Role of N- and C-terminal substituents on the CCK-B agonist-antagonist pharmacological profile of Boc-Trp-Phg-Asp-Nal-NH2 derivatives.

B. Roques, A. Bado, B. Ducos, 1996, Bioorganic & medicinal chemistry.

RATIONAL DRUG DESIGN BASED ON TARGET STRUCTURE ANALOGIES AND MOLECULAR BIOLOGY STUDIES

B. Roques, H. Rocquigny, C. Garbay, 1995, European Journal of Medicinal Chemistry.

Regioselective synthesis of imidazo[1,2-a][1,3,5]triazines and 3,4-dihydroimidazo[1,2-a][1,3,5]triazines from [1,3,5]triazin-2,4-diamines

C. Garbay, P. Dao, Huixiong Chen, 2013 .

SH2 and SH3 domains as targets for anti-proliferative agents.

M. Vidal, C. Garbay, V. Gigoux, 2001, Critical reviews in oncology/hematology.

Synthesis and Biological Characterization of [3H]BBL454, a New CCK2 Selective Radiolabeled Agonist Displaying Original Pharmacological Properties.

C. Garbay, R. Genet, B. Bellier, 2004 .

Structure-based design of new constrained cyclic agonists of the cholecystokinin CCK-B receptor.

B. Roques, A. Bado, B. Ducos, 1997, Journal of medicinal chemistry.

Heterogeneity of Cholecystokinin Receptors: A New Interest Towards the Development of CCK2 Agonists

C. Garbay, B. Bellier, V. Gigoux, 2001 .

Opposite effects of CCK(B) agonists in grooming behaviour in rats: further evidence for two CCK(B) subsites.

B. Roques, C. Garbay, N. Ladurelle, 1998, British journal of pharmacology.

Solution structure of GAP SH3 domain by 1H NMR and spatial arrangement of essential Ras signaling‐involved sequence.

N. Jullian, B. Roques, B. Tocqué, 1994, The EMBO journal.

NMR structure of the N-terminal SH3 domain of GRB2 and its complex with a proline-rich peptide from Sos

B. Roques, B. Tocqué, C. Garbay, 1994, Nature Structural Biology.

Lupane triterpenes from the leaves of the tropical rain forest tree Hopea odorata Roxb. and their cytotoxic activities

X. Cachet, C. Garbay, Françoise Raynaud, 2012 .

N-Carbamoylputrescine, a citrulline-derived polyamine, is not a significant citrulline metabolite in rats.

C. Garbay, L. Cynober, H. Chen, 2012, Analytical biochemistry.

Novel constrained CCK-B dipeptoid antagonists derived from pipecolic acid.

B. Roques, H. Meudal, C. Garbay, 1998, Bioorganic & medicinal chemistry letters.

GRB2 Links Signaling to Actin Assembly by Enhancing Interaction of Neural Wiskott-Aldrich Syndrome Protein (N-WASp) with Actin-related Protein (ARP2/3) Complex*

P. Sansonetti, A. Ducruix, M. Carlier, 2000, The Journal of Biological Chemistry.

5-Substituted [1]pyrindine derivatives with antiproliferative activity.

B. Ducommun, O. Mondésert, C. Garbay, 2010, European journal of medicinal chemistry.

Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities.

J. Herbeuval, D. Lietha, C. Garbay, 2014, Cancer letters.

STAT3-Stathmin Interactions Control Microtubule Dynamics in Migrating T-cells*

N. Verma, Y. Volkov, A. Davies, 2009, Journal of Biological Chemistry.

p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling.

Christiane Garbay, Perayot Pamonsinlapatham, C. Garbay, 2009, Biochimie.

Short interfering RNA (siRNA), a novel therapeutic tool acting on angiogenesis.

Christiane Garbay, C. Garbay, Yves Lepelletier, 2007, Biochimie.

A RasGAP SH3 Peptide Aptamer Inhibits RasGAP-Aurora Interaction and Induces Caspase-Independent Tumor Cell Death

M. Bickle, M. Schapira, N. Hugo, 2008, PloS one.

Grb2‐SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel

M. Poupon, B. Gril, M. Vidal, 2007, International journal of cancer.

M-CSF stimulated differentiation requires persistent MEK activity and MAPK phosphorylation independent of Grb2-Sos association and phosphatidylinositol 3-kinase activity.

Wang-Qing Liu, C. Garbay, G. Mouchiroud, 2005, Cellular signalling.

Design, synthesis, and evaluation of novel imidazo[1,2-a][1,3,5]triazines and their derivatives as focal adhesion kinase inhibitors with antitumor activity.

X. Coumoul, J. Herbeuval, D. Lietha, 2015, Journal of medicinal chemistry.

Restoration of TRAIL-induced apoptosis in resistant human pancreatic cancer cells by a novel FAK inhibitor, PH11.

D. Scott‐Algara, J. Herbeuval, C. Garbay, 2015, Cancer letters.

A Sos‐derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity

D. Cussac, B. Roques, M. Vidal, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Receptor-Based Virtual Ligand Screening for the Identification of Novel CDC25 Phosphatase Inhibitors

Bruno O. Villoutreix, Maria A. Miteva, Matthieu Montes, 2008, J. Chem. Inf. Model..

Structure-Based Design, Synthesis, and Characterization of the First Irreversible Inhibitor of Focal Adhesion Kinase.

John C. Dawson, X. Coumoul, M. Frame, 2018, ACS chemical biology.

Synthesis of novel 1,2,4-triazine scaffold as FAK inhibitors with antitumor activity.

D. Lietha, C. Garbay, M. Ethève-Quelquejeu, 2017, Bioorganic & medicinal chemistry letters.

Interleukin-2 Stimulation Induces Tyrosine Phosphorylation of p120-Cbl and CrkL and Formation of Multimolecular Signaling Complexes in T Lymphocytes and Natural Killer Cells*

J. Bertoglio, F. Gesbert, C. Garbay, 1998, The Journal of Biological Chemistry.

Synthesis, 3D-structure and stability analyses of NRPa-308, a new promising anti-cancer agent.

G. Pagès, R. Benhida, O. Hermine, 2019, Bioorganic & medicinal chemistry letters.

Protein kinases in the locus coeruleus and periaqueductal gray matter are involved in the expression of opiate withdrawal

B. Roques, O. Valverde, R. Maldonado, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

Synthesis of L-2,3,5,6-tetrafluoro-4-(phosphonomethyl) phenylalanine, a novel non-hydrolyzable phosphotyrosine mimetic and L-4-(phosphonodifluoromethyl)phenylalanine

Wang-Qing Liu, C. Garbay, B. Roques, 1997 .

High yielding microwave-assisted synthesis of 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines

C. Garbay, P. Dao, Huixiong Chen, 2010 .

Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity.

D. Lietha, C. Garbay, Y. Lepelletier, 2013, Bioorganic & medicinal chemistry letters.

High-Yielding Microwave-Assisted Synthesis of 2-(Arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines.

C. Garbay, P. Dao, Huixiong Chen, 2010 .

Polarizable water molecules in ligand-macromolecule recognition. Impact on the relative affinities of competing pyrrolopyrimidine inhibitors for FAK kinase.

Nohad Gresh, Jean-Philip Piquemal, Christiane Garbay, 2010, Journal of the American Chemical Society.

Differential effect of the inhibition of Grb2-SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement.

Abdelhafid Saci, Wang-Qing Liu, Michel Vidal, 2002, The Biochemical journal.

An alternative route to the proline derivative (2S,5R)-5-ethoxycarbonylmethyl-pyrrolidine-2-carboxylic acid from protected glutamic acid

C. Garbay, L. Bischoff, Marie-Priscille Brun, 2003 .

Inhibition of the EGF-stimulated cellular proliferation of ER 22 cells by hydroxybiphenyl derivatives.

B. Roques, B. Tocqué, C. Garbay, 1995, Journal of medicinal chemistry.

Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.

D. Cussac, M. Vidal, C. Garbay, 1999, Journal of molecular biology.

Differential Interactions of the Growth Factor Receptor-bound Protein 2 N-SH3 Domain with Son of Sevenless and Dynamin

D. Cussac, B. Roques, B. Tocqué, 1998, The Journal of Biological Chemistry.

NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model.

M. Montès, G. Pagès, R. Benhida, 2018, Cancer letters.

Cyclic peptides as VEGF receptor antagonist.

M. Vidal, C. Garbay, V. Goncalves, 2009, Advances in Experimental Medicine and Biology.

Does the ornithine–α-ketoglutarate ratio influence ornithine α-ketoglutarate metabolism in healthy rats?

C. Moinard, C. Garbay, L. Cynober, 2007 .

A novel non-phosphorylated potential antitumoral peptide inhibits STAT3 biological activity.

Wang-Qing Liu, C. Garbay, F. Cruzalegui, 2009, Biochimie.

Conformational analysis of a polyconjugated protein-binding ligand by joint quantum chemistry and polarizable molecular mechanics. Addressing the issues of anisotropy, conjugation, polarization, and multipole transferability

N. Gresh, J. Piquemal, C. Garbay, 2014, Journal of Molecular Modeling.

Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma

M. Montès, G. Pagès, Nathalie Lagarde, 2020, Journal of experimental & clinical cancer research : CR.

Capns1, a new binding partner of RasGAP-SH3 domain in K-Ras(V12) oncogenic cells: modulation of cell survival and migration.

Michel Vidal, Christiane Garbay, Perayot Pamonsinlapatham, 2008, Cellular signalling.

Assembly of Acetylcholinesterase Tetramers by Peptidic Motifs from the Proline-rich Membrane Anchor, PRiMA

J. Massoulie, S. Bon, Wang-Qing Liu, 2006, Journal of Biological Chemistry.

New Peptides Structurally Related to VEGF-A165 Exon-7 and -8 Encoded Domains Antagonize Its Binding to NRP-1 and VEGF-R1

O. Hermine, Wang-Qing Liu, C. Garbay, 2015, International Journal of Peptide Research and Therapeutics.

Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells.

J. Larghero, Wang-Qing Liu, C. Garbay, 2012, Cellular signalling.

Synthesis and structure-activity relationship of non-peptidic antagonists of neuropilin-1 receptor.

M. Montès, N. Gresh, J. Piquemal, 2014, Bioorganic & medicinal chemistry letters.

Structure-activity relationships in a series of 5-[(2,5-dihydroxybenzyl)amino]salicylate inhibitors of EGF-receptor-associated tyrosine kinase: importance of additional hydrophobic aromatic interactions.

B. Roques, B. Tocqué, J. Le Pecq, 1994, Journal of medicinal chemistry.

Is N-Carbamoyl Putrescine, the Decarboxylation Derivative of Citrulline, a Regulator of Muscle Protein Metabolism in Rats?

C. Garbay, L. Cynober, N. Neveux, 2019, Nutrients.

Synthesis and biological evaluation of a series of hydroxybenzylphenylamine derivatives as inhibitors of EGF receptor-associated tyrosine kinase activity.

B. Roques, B. Tocqué, C. Garbay, 1996, Anti-Cancer Drug Design.

Circular dichroic investigation of the native and non-native conformational states of the growth factor receptor-binding protein 2 N-terminal src homology domain 3: effect of binding to a proline-rich peptide from guanine nucleotide exchange factor.

B. Roques, Y. Mély, C. Garbay, 2000, Biochemistry.

Synthesis of Multifunctionalized 2-Iminothiazolidin-4-ones and Their 2-Arylimino Derivatives

L. Le Corre, C. Garbay, C. Gravier-Pelletier, 2016, Synthesis.

Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation

K. Cailliau, T. Issad, A. Burnol, 2010, FEBS letters.

The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix

J. Sussman, I. Silman, M. Harel, 2004 .

Synthesis and biological properties of new constrained CCK-B antagonists: discrimination of two affinity states of the CCK-B receptor on transfected CHO cells.

B. Roques, B. Ducos, H. Meudal, 1997, Journal of medicinal chemistry.

The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix

J. Sussman, I. Silman, M. Harel, 2004, The EMBO journal.

Synthesis of novel 1,2,4-triazine scaffold as FAK inhibitors with antitumor activity.

D. Lietha, C. Garbay, M. Ethève-Quelquejeu, 2017, Bioorganic & medicinal chemistry letters.