Guoning Zhang

发表

Synthesis and antiviral activity of a series of novel quinoline derivatives as anti-RSV or anti-IAV agents.

S. Cen, Minghua Wang, Yuan-hui Fu, 2021, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Substituted Indole and Its Analogs as Influenza A Virus Inhibitors

S. Cen, Guoning Zhang, Yujia Wang, 2018, Chemistry & biodiversity.

Design and evaluation of novel piperidine HIV-1 protease inhibitors with potency against DRV-resistant variants.

Jinming Zhou, S. Cen, Minghua Wang, 2021, European journal of medicinal chemistry.

Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants.

Jinming Zhou, C. Liang, S. Cen, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists.

Shuainan Liu, Z. Shen, Na Wang, 2017, European journal of medicinal chemistry.

Design, Synthesis, and Cytotoxic Activity of 3‐Aryl‐N‐hydroxy‐2‐(sulfonamido)propanamides in HepG2, HT‐1080, KB, and MCF‐7 Cells

Guoning Zhang, Juxian Wang, Mei Zhu, 2019, Chemistry & biodiversity.

Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

Guobin Zhang, Lin-Feng Chen, Guoning Zhang, 2017, Scientific Reports.

Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A.

S. Cen, Qiang Li, Yuan-hui Fu, 2019, European journal of medicinal chemistry.

Design, synthesis, and bioevaluation of a novel class of (E)-4-oxo-crotonamide derivatives as potent antituberculosis agents.

Xuefu You, Liyan Yu, Guoning Zhang, 2019, Bioorganic & medicinal chemistry letters.

A near-infrared fluorescent probe based on SNAr reaction for H2S/GSH detection in living cells and zebrafish

Guoning Zhang, Hong Zhao, Xiang Xia, 2019, Dyes and Pigments.

Novel Rhodamine-Derivated Dual-Responsive Colorimetric Fluorescent Chemoprobe for the Hypersensitive Detection of Ga3+ and Hg2+ and Biological Imaging

Zhifei Wang, Guoning Zhang, Mei Zhu, 2019, Industrial & Engineering Chemistry Research.

A FRET-based colorimetric and ratiometric fluorescent probe for the detection of Cu2+ with a new trimethylindolin fluorophore

Guoning Zhang, Mei Zhu, Yucheng Wang, 2019, New Journal of Chemistry.

Rational Design and Systemic Appraisal of an EGFR-Targeting Antibody-Drug Conjugate LR-DM1 for Pancreatic Cancer.

Minghua Wang, Guoning Zhang, Juxian Wang, 2022, Journal of medicinal chemistry.

Design, synthesis and metabolic regulation effect of farnesoid X receptor (FXR) antagonistic benzoxepin-5-ones

Z. Shen, Yi Huan, Su-juan Sun, 2017 .

The mechanism and pharmacodynamics of 2-((1H-indol-3-yl)thio/sulfinyl)-N-pheny acetamide derivative as a novel inhibitor against human respiratory syncytial virus

S. Cen, Yuan-hui Fu, Xiang-Lei Peng, 2022, Journal of enzyme inhibition and medicinal chemistry.

Discovery of 1,8-naphthalidine derivatives as potent anti-hepatic fibrosis agents via repressing PI3K/AKT/Smad and JAK2/STAT3 pathways.

Zhen Lu, Guoning Zhang, Juxian Wang, 2021, Bioorganic & medicinal chemistry.

Structural Elucidation and Supercapacitive Performance in a 1D Cadmium(II) Polymer Based on Pyrazole Carboxylic Acid

Guoning Zhang, C. Feng, Chang‐Peng Lv, 2019, Journal of Inorganic and Organometallic Polymers and Materials.

Synthesis and biological evaluation of novel N, N'-diarylurea derivatives as potent antibacterial agents against MRSA.

Xuefu You, Minghua Wang, Guoning Zhang, 2022, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological activity evaluation of a series of pleuromutilin derivatives with novel C14 side chains.

Guoning Zhang, Mei Zhu, Ju-xian Wang, 2020, Bioorganic & medicinal chemistry letters.

Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands.

Guoning Zhang, Juxian Wang, Mei Zhu, 2019, Bioorganic & medicinal chemistry letters.

Discovery and optimization of 2-((1H-indol-3-yl)thio)-N-benzyl-acetamides as novel SARS-CoV-2 RdRp inhibitors

S. Cen, Minghua Wang, Guoning Zhang, 2021, European Journal of Medicinal Chemistry.

SAR studies on 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles as inhibitors of Mtb shikimate dehydrogenase for the development of novel antitubercular agents

Guoning Zhang, Juxian Wang, Yucheng Wang, 2015 .

One-Pot Synthesis of 3-Functionalized 4-Hydroxycoumarin under Catalyst-Free Conditions

Yang Gao, Guoning Zhang, Juxian Wang, 2018, Molecules.

An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction

Guoning Zhang, Juxian Wang, Mei Zhu, 2018, Molecules.

Preliminary SAR and biological evaluation of antitubercular triazolothiadiazine derivatives against drug-susceptible and drug-resistant Mtb strains.

Guoning Zhang, Juxian Wang, Yucheng Wang, 2017, Bioorganic & medicinal chemistry.

Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study

Jinming Zhou, S. Cen, Guoning Zhang, 2020, PloS one.

Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1' ligand to enhance binding with S1' subsite.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, Bioorganic & medicinal chemistry.

Synthesis and evaluation of potent human immunodeficiency virus 1 protease inhibitors with epimeric isopropanol as novel P1' ligands.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, Future medicinal chemistry.

Rational design and Structure-Activity relationship of coumarin derivatives effective on HIV-1 protease and partially on HIV-1 reverse transcriptase.

Jinming Zhou, C. Liang, S. Cen, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of new HIV-1 protease inhibitors with purine bases as P2-ligands.

S. Cen, Guoning Zhang, Juxian Wang, 2019, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation.

Zhiheng Yang, Guoning Zhang, Juxian Wang, 2017, European journal of medicinal chemistry.

Simple and efficient rhodamine-derived VO2+ and Cu2+-responsive colorimetric and reversible fluorescent chemosensors toward the design of multifunctional materials

Zhifei Wang, Guoning Zhang, Yucheng Wang, 2019, Journal of Materials Chemistry C.

Ultrafast response fluorescent probe with red-emission for monitoring hydrogen sulfide in vivo and in vitro

Guoning Zhang, Mei Zhu, Hong Zhao, 2019, Journal of Photochemistry and Photobiology A: Chemistry.

A Three-Dimensional Cd(II)-Coordination Polymer: Crystal Structure, Electrochemiluminescent Property and Novel Topology

K. Zou, Guoning Zhang, Hong Zhao, 2021, Journal of Inorganic and Organometallic Polymers and Materials.

Design and biological evaluation of cinnamic and phenylpropionic amide derivatives as novel dual inhibitors of HIV-1 protease and reverse transcriptase.

Jinming Zhou, S. Cen, Minghua Wang, 2021, European journal of medicinal chemistry.

Antibacterial Activity and Structure−Activity Relationship of a Series of Newly Synthesized Pleuromutilin Derivatives

Guoning Zhang, Mei Zhu, Ju-xian Wang, 2019, Chemistry & biodiversity.

Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives.

S. Cen, Minghua Wang, Guoning Zhang, 2020, Bioorganic & medicinal chemistry letters.

Novel HIV-1 Protease Inhibitors with Morpholine as the P2 Ligand to Enhance Activity against DRV-Resistant Variants.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, ACS medicinal chemistry letters.

An Ultra‐Sensitive Naphthalimide‐Derived Fluorescent Probe for the Detection of Cu2+in Water Samples and Living Cells

Guoning Zhang, Mei Zhu, Hong Zhao, 2019, ChemistrySelect.

Design, synthesis and in vitro anti-influenza A virus evaluation of novel quinazoline derivatives containing S-acetamide and NH-acetamide moieties at C-4.

S. Cen, Minghua Wang, Guoning Zhang, 2020, European journal of medicinal chemistry.

Electrochemiluminescence properties and luminescence sensing of four novel polymers derived from 3-(pyrazin-2-yl)-1H-pyrazole-5-carboxylic acid

Guoning Zhang, Hong Zhao, Yu-cheng Wang, 2021, CrystEngComm.

Small molecule T63 suppresses osteoporosis by modulating osteoblast differentiation via BMP and WNT signaling pathways

Lin-Feng Chen, Guoning Zhang, Yu-cheng Wang, 2017, Scientific Reports.

Design, synthesis and biological evaluation of HIV-1 protease inhibitors with morpholine derivatives as P2 ligands in combination with cyclopropyl as P1' ligand.

Guoning Zhang, Juxian Wang, Mei Zhu, 2020, Bioorganic & Medicinal Chemistry Letters.

Design, synthesis, and anti-influenza A virus activity evaluation of novel indole containing derivatives of triazole.

S. Cen, Guoning Zhang, Jian-yuan Zhao, 2022, Bioorganic & medicinal chemistry letters.

2-((1H-indol-3-yl)thio)-N-phenyl-acetamides: SARS-CoV-2 RNA-dependent RNA polymerase inhibitors

Zhenlong Liu, Fei Guo, S. Cen, 2021, Antiviral Research.

Structure Modification of FXR Antagonistic Chalcones and Their Inhibitory Effects on NSCLC Cell Proliferation and Metastasis

Guoning Zhang, Jinsong Liu, Guangyao Lv, 2022, ChemMedChem.