Juxian Wang

发表

Synthesis and antiviral activity of a series of novel quinoline derivatives as anti-RSV or anti-IAV agents.

S. Cen, Minghua Wang, Yuan-hui Fu, 2021, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Substituted Indole and Its Analogs as Influenza A Virus Inhibitors

S. Cen, Guoning Zhang, Yujia Wang, 2018, Chemistry & biodiversity.

Alcohol Participates in the Synthesis of Functionalized Coumarin-Fused Pyrazolo[3,4-b]Pyridine from a One-Pot Three-Component Reaction

Juxian Wang, Wei Lin, Cangwei Zhuang, 2019, Molecules.

Asymmetric combinational "metal-biocatalytic system": One approach to chiral 2-subsituted-tetrahydroquinoline-4-ols towards two-step one-pot processes in aqueous media

Ke Li, Juxian Wang, W. Yuan, 2017 .

Design and evaluation of novel piperidine HIV-1 protease inhibitors with potency against DRV-resistant variants.

Jinming Zhou, S. Cen, Minghua Wang, 2021, European journal of medicinal chemistry.

Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants.

Jinming Zhou, C. Liang, S. Cen, 2019, European journal of medicinal chemistry.

Design, Synthesis, and Cytotoxic Activity of 3‐Aryl‐N‐hydroxy‐2‐(sulfonamido)propanamides in HepG2, HT‐1080, KB, and MCF‐7 Cells

Guoning Zhang, Juxian Wang, Mei Zhu, 2019, Chemistry & biodiversity.

Design and synthesis of 2-((1H-indol-3-yl)thio)-N-phenyl-acetamides as novel dual inhibitors of respiratory syncytial virus and influenza virus A.

S. Cen, Qiang Li, Yuan-hui Fu, 2019, European journal of medicinal chemistry.

Design, synthesis, and bioevaluation of a novel class of (E)-4-oxo-crotonamide derivatives as potent antituberculosis agents.

Xuefu You, Liyan Yu, Guoning Zhang, 2019, Bioorganic & medicinal chemistry letters.

An efficient three‐component synthesis of hexahydroquinoline derivatives in ionic liquid

D. Shi, Juxian Wang, G. Shen, 2011 .

Rational Design and Systemic Appraisal of an EGFR-Targeting Antibody-Drug Conjugate LR-DM1 for Pancreatic Cancer.

Minghua Wang, Guoning Zhang, Juxian Wang, 2022, Journal of medicinal chemistry.

Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.

D. Jain, J. Boyer, X. Ouyang, 2017, JCI insight.

Discovery of 1,8-naphthalidine derivatives as potent anti-hepatic fibrosis agents via repressing PI3K/AKT/Smad and JAK2/STAT3 pathways.

Zhen Lu, Guoning Zhang, Juxian Wang, 2021, Bioorganic & medicinal chemistry.

Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands.

Guoning Zhang, Juxian Wang, Mei Zhu, 2019, Bioorganic & medicinal chemistry letters.

Substituted 4-oxo-crotonic acid derivatives as a new class of protein kinase B (PknB) inhibitors: synthesis and SAR study

Juxian Wang, Yucheng Wang, Li-Yan Yu, 2017 .

Ultrasound-Promoted One-Pot, Four-Component Synthesis of Pyridin-2(1H)-One Derivatives

D. Shi, Juxian Wang, Yucheng Wang, 2013, Molecules.

Ultrasound-Promoted One-Pot, Three-Component Synthesis of Spiro[indoline-3,1'-pyrazolo[1,2-b]phthalazine] Derivatives

Yi Zou, D. Shi, Juxian Wang, 2012, Molecules.

Microwave-Assisted Improved Synthesis of Pyrrolo[2,3,4-kl]acridine and Dihydropyrrolo[2,3,4-kl]acridine Derivatives Catalyzed by Silica Sulfuric Acid

D. Shi, Juxian Wang, Yucheng Wang, 2013, Molecules.

Enantioselective synthesis of 1,2,3,4-tetrahydroquinoline-4-ols and 2,3-dihydroquinolin-4(1H)-ones via a sequential asymmetric hydroxylation/diastereoselective oxidation process using Rhodococcus equi ZMU-LK19.

D. Zheng, Juxian Wang, Nanwei Wan, 2017, Organic & biomolecular chemistry.

A novel reductive cyclization of o-nitrobenzamides and ketones promoted by low-valent titanium reagent

D. Shi, Juxian Wang, Qiya Zhuang, 2010 .

Facile Synthesis of Substituted Quinazolin‐4‐(3H)‐ones Using Low‐Valence Titanium Reagent

D. Shi, Juxian Wang, Xiang-Shan Wang, 2004 .

Synthesis of quinazolin-4(3H)-ones and 1,2-dihydroquinazolin-4(3H)-ones with the aid of a low-valent titanium reagent

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

An efficient synthesis of quinazoline derivatives with the aid of low‐valent titanium reagent

D. Shi, Juxian Wang, Xiang-Shan Wang, 2005 .

Synthesis of Quinazolin-4(3H)-ones and 1,2-Dihydroquinazolin-4(3H)-ones with the Aid of a Low-Valent Titanium Reagent.

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

An Efficient Synthesis of Novel Dispirooxindole Derivatives via One-Pot Three-Component 1,3-Dipolar Cycloaddition Reactions

Qian Zhao, D. Shi, Juxian Wang, 2012, Molecules.

Discovery and optimization of 2-((1H-indol-3-yl)thio)-N-benzyl-acetamides as novel SARS-CoV-2 RdRp inhibitors

S. Cen, Minghua Wang, Guoning Zhang, 2021, European Journal of Medicinal Chemistry.

SAR studies on 1,2,4-triazolo[3,4-b][1,3,4]thiadiazoles as inhibitors of Mtb shikimate dehydrogenase for the development of novel antitubercular agents

Guoning Zhang, Juxian Wang, Yucheng Wang, 2015 .

Regioselective synthesis and in vitro anticancer activity of 4-aza-podophyllotoxin derivatives catalyzed by L-proline.

D. Shi, Juxian Wang, Hui Chen, 2010, Journal of combinatorial chemistry.

One-Pot Synthesis of 3-Functionalized 4-Hydroxycoumarin under Catalyst-Free Conditions

Yang Gao, Guoning Zhang, Juxian Wang, 2018, Molecules.

A Facile Synthesis of 1,2-Dihydroquinazolin-4(3H)-Ones with the Aid of a Low-Valent Titanium Reagent †

D. Shi, Juxian Wang, Qiya Zhuang, 2003 .

An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction

Guoning Zhang, Juxian Wang, Mei Zhu, 2018, Molecules.

Preliminary SAR and biological evaluation of antitubercular triazolothiadiazine derivatives against drug-susceptible and drug-resistant Mtb strains.

Guoning Zhang, Juxian Wang, Yucheng Wang, 2017, Bioorganic & medicinal chemistry.

Facile Synthesis of Substituted Quinazolin-4-(3H)-ones Using Low-Valence Titanium Reagent.

D. Shi, Juxian Wang, Xiang-Shan Wang, 2004 .

A Novel Reductive Cross-coupling Reaction of 2-nitrobenzoic Hydrazides and Aldehydes or Ketones Promoted by the Low-valence Titanium Reagent: An Access to 2,3,4,5-tetrahydro-1H-1,3,4-benzotriazepine-5-one Derivatives

D. Shi, Juxian Wang, Qiya Zhuang, 2005 .

5,5‐Dimethyl‐2,3‐diphenyl‐5,6‐dihydroimidazo[1,2‐c]quinazoline

D. Shi, Juxian Wang, Xiang-Shan Wang, 2004 .

2-Chloro-6-methyl-8,9-diphenylimidazo[1,2-c]quinazoline

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

5,5-Dimethyl-8,9-methylenedioxy-2,3-diphenyl-5,6-dihydroimidazo[1,2-c]quinazoline

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

9-Chloro-5,5-dimethyl-2,3-diphenyl-2,3-dihydroimidazo[1,2-c]quinazoline

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

3-Amino-1-(4-fluorophenyl)-3a,3b,6,7-tetrahydrobenz[4,5]indene-2-carbonitrile

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

A Novel Reductive Cross-Coupling Reaction of N-Aryl-2-Nitrobenzamide and Triethyl Orthoformate Promoted by the TiCl4/Sm System: An Access to 3-Arylquinazolin-4 (3H)-Ones

D. Shi, Juxian Wang, Qiya Zhuang, 2003 .

An Efficient Synthesis of Quinazoline Derivatives with the Aid of Low‐Valent Titanium Reagent.

D. Shi, Juxian Wang, Xiang-Shan Wang, 2005 .

A Novel Reductive Cyclisation of o-Nitrochalcones Promoted by Low-Valent Titanium: An Access to 2-Arylquinolines and 5,6-Dihydrobenz[c]Acridines †

D. Shi, Juxian Wang, Xiang-Shan Wang, 2003 .

Piperidine scaffold as the novel P2-ligands in cyclopropyl-containing HIV-1 protease inhibitors: Structure-based design, synthesis, biological evaluation and docking study

Jinming Zhou, S. Cen, Guoning Zhang, 2020, PloS one.

Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1' ligand to enhance binding with S1' subsite.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, Bioorganic & medicinal chemistry.

Synthesis and evaluation of potent human immunodeficiency virus 1 protease inhibitors with epimeric isopropanol as novel P1' ligands.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, Future medicinal chemistry.

Rational design and Structure-Activity relationship of coumarin derivatives effective on HIV-1 protease and partially on HIV-1 reverse transcriptase.

Jinming Zhou, C. Liang, S. Cen, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of new HIV-1 protease inhibitors with purine bases as P2-ligands.

S. Cen, Guoning Zhang, Juxian Wang, 2019, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent HIV-1 protease inhibitors with (S)-tetrahydrofuran-tertiary amine-acetamide as P2-ligand: Structure-activity studies and biological evaluation.

Zhiheng Yang, Guoning Zhang, Juxian Wang, 2017, European journal of medicinal chemistry.

Design and biological evaluation of cinnamic and phenylpropionic amide derivatives as novel dual inhibitors of HIV-1 protease and reverse transcriptase.

Jinming Zhou, S. Cen, Minghua Wang, 2021, European journal of medicinal chemistry.

Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives.

S. Cen, Minghua Wang, Guoning Zhang, 2020, Bioorganic & medicinal chemistry letters.

Structure based design and evaluation of benzoheterocycle derivatives as potential dual HIV-1 protease and reverse transcriptase inhibitors.

Jinming Zhou, S. Cen, Minghua Wang, 2023, European journal of medicinal chemistry.

A kind of HIV-1 protease inhibitors containing phenols with antiviral activity against DRV-resistant variants.

Jinming Zhou, S. Cen, Minghua Wang, 2022, Bioorganic & medicinal chemistry.

Novel HIV-1 Protease Inhibitors with Morpholine as the P2 Ligand to Enhance Activity against DRV-Resistant Variants.

Jinming Zhou, S. Cen, Guoning Zhang, 2020, ACS medicinal chemistry letters.

Design, synthesis and in vitro anti-influenza A virus evaluation of novel quinazoline derivatives containing S-acetamide and NH-acetamide moieties at C-4.

S. Cen, Minghua Wang, Guoning Zhang, 2020, European journal of medicinal chemistry.

A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides

Juxian Wang, Yue Zhao, Jinfeng Ren, 2016, Acta pharmaceutica Sinica. B.

Discovery and development of benzene sulfonamide derivatives as anti-hepatic fibrosis agents.

Yiming Li, Minghua Wang, Juxian Wang, 2023, Bioorganic & medicinal chemistry letters.

Synthesis and antitumor activity of ATB-429 derivatives containing a nitric oxide-releasing moiety.

Guimin Xia, Juxian Wang, Mingliang Liu, 2016, Bioorganic & medicinal chemistry letters.

Design and Evaluation of Novel HIV-1 Protease Inhibitors Containing Phenols or Polyphenols as P2 Ligands with High Activity against DRV-Resistant HIV-1 Variants

Jinming Zhou, S. Cen, Juxian Wang, 2022, International journal of molecular sciences.

Design, synthesis and biological evaluation of protease inhibitors containing morpholine cores with remarkable potency against both HIV-1 subtypes B and C.

Jinming Zhou, S. Cen, Minghua Wang, 2022, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of HIV-1 protease inhibitors with morpholine derivatives as P2 ligands in combination with cyclopropyl as P1' ligand.

Guoning Zhang, Juxian Wang, Mei Zhu, 2020, Bioorganic & Medicinal Chemistry Letters.

tert-Butyl 4-carbamoyl-3-methoxyimino-4-methylpiperidine-1-carboxylate

Juxian Wang, Yucheng Wang, Mingliang Liu, 2008, Acta Crystallographica Section E.

Verbalide A~F: new phthalide derivatives from the endophytic fungus Preussia sp. CPCC 400972.

Liyan Yu, S. Cen, Jian-yuan Zhao, 2023, The Journal of antibiotics.

Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.

D. Jain, J. Boyer, X. Ouyang, 2017, JCI insight.

Design, synthesis, and biological evaluation of novel HIV-1 protease inhibitors containing pyrrolidine-derived P2 ligands to combat drug-resistant variant.

S. Cen, Minghua Wang, Juxian Wang, 2023, European journal of medicinal chemistry.