P. Harris

发表

Synthesis of endolides A and B: naturally occurring N-methylated cyclic tetrapeptides.

Emma K Davison, M. Brimble, A. Cameron, 2019, MedChemComm.

A Concise Synthetic Strategy Towards the Novel Calcium-dependent Lipopeptide Antibiotic, Malacidin A and Analogues

M. Brimble, G. Cook, A. Cameron, 2021, Frontiers in Chemistry.

Synthesis and activity of a diselenide bond mimetic of the antimicrobial protein caenopore-5

M. Brimble, G. Cook, Kiel Hards, 2015, Chemical science.

Synthesis of isotopically labelled αCGRP8-37 and its lipidated analogue.

M. Brimble, D. Hay, P. Harris, 2020, Journal of labelled compounds & radiopharmaceuticals.

Synthesis of fluorescein-labelled O-mannosylated peptides as components for synthetic vaccines: comparison of two synthetic strategies.

M. Brimble, P. Dunbar, P. Harris, 2008, Organic & biomolecular chemistry.

Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.

E. Baker, S. Panjikar, M. Brimble, 2016, Angewandte Chemie.

Total chemical synthesis of an Orf virus protein, ORFV002, an inhibitor of the master gene regulator NF‐κB

E. Baker, S. Kent, M. Brimble, 2014, Biopolymers.

Enhancing the Oral Bioavailability of Peptide Drugs by using ChemicalModification and Other Approaches

M. Brimble, Jingyuan Wen, P. Harris, 2014 .

Synthesis and biological evaluation of S-lipidated lipopeptides of a connexin 43 channel inhibitory peptide.

Sung‐Hyun Yang, M. Brimble, S. O'Carroll, 2020, RSC medicinal chemistry.

Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

J. Elmquist, C. Buchanan, M. Brimble, 2017, Molecular metabolism.

Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

M. Brimble, P. Harris, 2006, Organic & biomolecular chemistry.

Pharmacological characterization and investigation of N-terminal loop amino acids of adrenomedullin 2 that are important for receptor activation.

M. Brimble, D. Hay, P. Harris, 2019, Biochemistry.

Structure–activity relationships of the N-terminus of calcitonin gene-related peptide: key roles of alanine-5 and threonine-6 in receptor activation

M. Brimble, D. Hay, D. Poyner, 2013, British journal of pharmacology.

Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate.

M. Brimble, P. Harris, Kuo-yuan Hung, 2010, The Journal of organic chemistry.

Preparation of truncated orf virus entry fusion complex proteins by chemical synthesis

E. Baker, M. Brimble, P. Harris, 2014, Journal of peptide science : an official publication of the European Peptide Society.

Synthetic peptides designed to modulate adiponectin assembly improve obesity‐related metabolic disorders

A. Mitra, M. Radjainia, P. Harris, 2017, British journal of pharmacology.

A highly conserved tryptophan in the N‐terminal variable domain regulates disulfide bond formation and oligomeric assembly of adiponectin

A. Mitra, M. Schmitz, M. Radjainia, 2012, The FEBS journal.

An Efficient Chemical Synthesis of Lassomycin Enabled by an On-Resin Lactamisation–Off-Resin Methanolysis Strategy and Preparation of Chemical Variants

M. Brimble, G. Cook, P. Harris, 2017 .

The role for IGF-1-derived small neuropeptides as a therapeutic target for neurological disorders

A. Gunn, M. Brimble, P. Harris, 2015, Expert opinion on therapeutic targets.

Neuroprotection with Glycine-2-Methylproline-Glutamate (G-2MePE) after hypoxic-ischemic brain injury in adult rats

A. Gunn, M. Brimble, P. Harris, 2014 .

NNZ-2566: A Gly–Pro–Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke

P. Gluckman, M. Brimble, E. Sirimanne, 2009, Journal of the Neurological Sciences.

Using Chemical Synthesis to Probe Structure-Activity Relationships of the Glycoactive Bacteriocin Glycocin F.

Sung‐Hyun Yang, M. Brimble, G. Norris, 2018, ACS chemical biology.

Total chemical synthesis of glycocin F and analogues: S-glycosylation confers improved antimicrobial activity† †Electronic supplementary information (ESI) available: Experimental details for the synthesis of all peptides, analytical LC and HR-MS, and circular dichroism data. See DOI: 10.1039/c7sc043

Sung‐Hyun Yang, M. Brimble, G. Norris, 2018, Chemical science.

Synthesis of the antimicrobial S-linked glycopeptide, glycocin F.

Sung‐Hyun Yang, M. Brimble, G. Norris, 2015, Chemistry.

Incorporation of 'click' chemistry glycomimetics dramatically alters triple-helix stability in an adiponectin model peptide.

G. Cooper, Sung‐Hyun Yang, M. Brimble, 2017, Organic & biomolecular chemistry.

A potent fluorescent calcitonin gene‐related peptide analogue enables visualization of receptor internalization

M. Brimble, D. Hay, D. Poyner, 2019, Peptide Science.

Regulation and Quality Control of Adiponectin Assembly by Endoplasmic Reticulum Chaperone ERp44*

A. Mitra, M. Radjainia, M. Brimble, 2015, The Journal of Biological Chemistry.

A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography

Dong Jun Lee, M. Brimble, P. Harris, 2012, Journal of peptide science : an official publication of the European Peptide Society.

Supplementation of Blackcurrant Anthocyanins Increased Cyclic Glycine-Proline in the Cerebrospinal Fluid of Parkinson Patients: Potential Treatment to Improve Insulin-Like Growth Factor-1 Function

T. Anderson, M. MacAskill, J. Dalrymple-Alford, 2018, Nutrients.

Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

M. Brimble, F. Sieg, P. Harris, 2005, Bioorganic & medicinal chemistry.

Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).

M. Brimble, F. Sieg, P. Harris, 2005, Bioorganic & medicinal chemistry.

Synthesis of proline-modified analogues of the neuroprotective agent glycyl-l-prolyl-glutamic acid (GPE)

M. Brimble, P. Harris, V. Muir, 2005 .

Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis.

J. Cornish, K. Callon, M. Watson, 2012, Bioorganic & medicinal chemistry.

Synthesis and Systematic Study on the Effect of Different PEG Units on Stability of PEGylated, Integrin-αvβ6-Specific A20FMDV2 Analogues in Rat Serum and Human Plasma

M. Brimble, A. Desai, P. Harris, 2022, Molecules.

An investigation of the role of the adiponectin variable domain on the stability of the collagen‐like domain

A. Mitra, M. Radjainia, M. Brimble, 2014, Biopolymers.

Synthesis of MUC1 Neoglycopeptides using efficient microwave-enhanced chaotrope-assisted click chemistry.

Dong Jun Lee, M. Brimble, P. Harris, 2011, Organic & biomolecular chemistry.

Lipidation of Cysteine or Cysteine-Containing Peptides Using the Thiol-Ene Reaction (CLipPA)

Sung‐Hyun Yang, M. Brimble, P. Harris, 2016 .

N-Vinyl Acrylamides: Versatile Heterobifunctional Electrophiles for Thiol-Thiol Bioconjugations.

M. Brimble, P. Harris, P. Hume, 2022, Journal of the American Chemical Society.

Structure-activity relationship study of the tumour-targeting peptide A20FMDV2 via modification of Lys16, Leu13, and N- and/or C-terminal functionality.

M. Brimble, J. Marshall, A. Desai, 2017, European journal of medicinal chemistry.

A Single Pseudoproline and Microwave Solid Phase Peptide Synthesis Facilitates an Efficient Synthesis of Human Amylin 1–37

M. Brimble, D. Hay, P. Harris, 2012, International Journal of Peptide Research and Therapeutics.

Ruthenium-catalysed ortho vinylation of aromatic ketones with alkynes; unexpected cyclopentaannulation

P. Harris, C. Rickard, P. D. Woodgate, 1999 .

A synthetic approach to ‘click’ neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc03409e

M. Brimble, A. Cameron, P. Harris, 2018, Chemical science.

The Total Chemical Synthesis and Biological Evaluation of the Cationic Antimicrobial Peptides, Laterocidine and Brevicidine.

M. Brimble, A. Cameron, P. Harris, 2021, Journal of natural products.

Aminovinyl Cysteine Containing Peptides: A Unique Motif That Imparts Key Biological Activity

M. Brimble, P. Harris, Elyse T. Williams, 2021, JACS Au.

Synthesis and biological evaluation of novel teixobactin analogues.

M. Brimble, G. Cook, P. Harris, 2017, Organic & biomolecular chemistry.

Antibody responses to Collagen Peptides and Streptococcal Collagen-like 1 Proteins in Acute Rheumatic Fever Patients.

M. Baker, R. Dobson, M. Brimble, 2021, Pathogens and disease.

Regulation and quality control of adiponectin assembly by ERp44*

A. Mitra, M. Radjainia, M. Brimble, 2015 .

Peptide Lipidation – A Synthetic Strategy to Afford Peptide Based Therapeutics

Sung‐Hyun Yang, M. Brimble, P. Harris, 2017, Advances in experimental medicine and biology.

Synthesis and assignment of stereochemistry of the antibacterial cyclic peptide xenematide.

M. Brimble, P. Harris, Amanda M. Heapy, 2011, Organic & biomolecular chemistry.

Synthesis of the peptaibol framework of the anticancer agent culicinin D: stereochemical assignment of the AHMOD moiety.

M. Brimble, P. Harris, Kuo-yuan Hung, 2012, Organic letters.

Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation

E. Baker, M. Brimble, T. Proft, 2014, PloS one.

On resin synthesis and cross-linking of collagen peptides containing the advanced glycation end-product pyrraline via Maillard condensation.

M. Brimble, P. Harris, James M. Wood, 2015, Chemical communications.

Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D

J. Smaill, Sung‐Hyun Yang, M. Brimble, 2015 .

Total Synthesis and Stereochemical Revision of the Anti-Tuberculosis Peptaibol Trichoderin A.

M. Brimble, G. Cook, P. Harris, 2016, Organic letters.

Cyclic glycine-proline normalizes systolic blood pressure in high-fat diet-induced obese male rats.

M. Vickers, C. Reynolds, C. Gray, 2019, Nutrition, metabolism, and cardiovascular diseases : NMCD.

Synthesis of Antimicrobial Lipopeptides Using the "CLipPA" Thiol-Ene Reaction.

M. Brimble, A. Cameron, P. Harris, 2020, Methods in molecular biology.

Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex.

C. Reynolds, T. Sakmar, M. Brimble, 2018, Biochemistry.

Photoa ffi nity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor / Receptor Activity-Modifying Protein 1 ( CLR / RAMP 1 ) Complex

C. Reynolds, T. Sakmar, M. Brimble, 2018 .

Maternally Administered Cyclic Glycine-Proline Increases Insulin-Like Growth Factor-1 Bioavailability and Novelty Recognition in Developing Offspring.

C. Mcmahon, M. Brimble, Kuljeet Singh, 2016, Endocrinology.

Synthesis and Biological Evaluation of Termini-Modified and Cyclic Variants of the Connexin43 Inhibitor Peptide5

M. Brimble, S. O'Carroll, P. Harris, 2022, Frontiers in Chemistry.

Total synthesis of the cyclic depsipeptide YM-280193, a platelet aggregation inhibitor.

P. Little, M. Brimble, P. Harris, 2015, Organic letters.

Thiol-ene enabled preparation of S-lipidated anti-HBV peptides.

M. Brimble, A. Cameron, P. Harris, 2020, Organic & biomolecular chemistry.

Synthesis of cyclic proline-containing peptides via ring-closing metathesis.

P. Gluckman, M. Brimble, P. Harris, 2003, Organic letters.

Synthesis and antiproliferative activity of C- and N-terminal analogues of culicinin D.

J. Smaill, M. Brimble, P. Harris, 2020, Bioorganic & medicinal chemistry letters.

Anticholinesterase Inhibition, Drug-Likeness Assessment, and Molecular Docking Evaluation of Milk Protein-Derived Opioid Peptides for the Control of Alzheimer’s Disease

M. Brimble, D. Agyei, Junyi Dai, 2022, Dairy.

Recent Progress in the Synthesis of Homogeneous Erythropoietin (EPO) Glycoforms

Sung‐Hyun Yang, M. Brimble, P. Harris, 2020, Chembiochem : a European journal of chemical biology.

The Chemical Synthesis of the Collagenous Domain of the Hormone Adiponectin

M. Brimble, P. Harris, 2012, International Journal of Peptide Research and Therapeutics.

Distinct Patterns of Internalization of Different Calcitonin Gene-Related Peptide Receptors.

M. Brimble, D. Hay, P. Harris, 2020, ACS pharmacology & translational science.

Use of (S)‐5‐(2‐Methylpyrrolidin‐2‐yl)‐1H‐tetrazole as a Novel and Enantioselective Organocatalyst for the Aldol Reaction

M. Brimble, P. Harris, D. Barker, 2008 .

Identification of Key Functional Motifs of Native Amelogenin Protein for Dental Enamel Remineralisation

M. Brimble, P. Harris, K. C. Li, 2020, Molecules.

Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R.

B. Forbes, M. Brimble, A. Abell, 2016, Organic & biomolecular chemistry.

Functionalisation of tetraalkylsilanes derived from CH activation; towards annulations of diterpenoids

P. Harris, C. Rickard, P. D. Woodgate, 2000 .

An important side reaction using the thiol, 3,6‐dioxa‐1,8‐octanedithiol (DODT), in 9‐fluorenylmethoxycarbonyl‐based solid phase peptide synthesis

Sung‐Hyun Yang, M. Brimble, P. Harris, 2014, Journal of Peptide Science.

Functionalisation of Alkylalkoxysilanes. Studies Towards Annulations of Diterpenoids

P. Harris, P. D. Woodgate, 2000 .

Synthesis and SAR analysis of lipovelutibols B and D and their lipid analogues.

M. Brimble, P. Dunbar, A. Cameron, 2019, The Journal of organic chemistry.

Ruthenium-catalysed ortho alkylation of hydroxyacetophenones; the functionalisation of ring C aromatic diterpenoids

P. Harris, P. D. Woodgate, 1996 .

Total synthesis of the proposed structure of talarolide A.

M. Brimble, P. Harris, I. Leung, 2018, Organic & biomolecular chemistry.

Total Synthesis and Conformational Study of Callyaerin A: Anti-Tubercular Cyclic Peptide Bearing a Rare Rigidifying (Z)-2,3- Diaminoacrylamide Moiety.

M. Brimble, G. Cook, P. Harris, 2018, Angewandte Chemie.

Synthesis of Enediamino Amino Acid Analogues and Peptides

M. Brimble, P. Harris, Shengping Zhang, 2017 .

Solid‐Phase Synthesis of the Peptaibol Alamethicin U‐22324 by Using a Double‐Linker Strategy

M. Brimble, P. Harris, Kuo-yuan Hung, 2017 .

Photo-induced radical thiol-ene chemistry: a versatile toolbox for peptide-based drug design.

M. Brimble, P. Harris, Marzieh Ahangarpour, 2021, Chemical Society reviews.

Synthesis and neuroprotective activity of analogues of glycyl-L-prolyl-L-glutamic acid (GPE) modified at the alpha-carboxylic acid.

M. Brimble, F. Sieg, P. Harris, 2005, Bioorganic & medicinal chemistry.

Three Decades of Amyloid Beta Synthesis: Challenges and Advances

Margaret A. Brimble, M. Brimble, P. Harris, 2019, Front. Chem..

Direct synthesis of cyclic lipopeptides using intramolecular native chemical ligation and thiol-ene CLipPA chemistry.

M. Brimble, A. Cameron, P. Harris, 2020, Organic & biomolecular chemistry.

Chemical synthesis of γ‐secretase activating protein using pseudoglutamines as ligation sites

M. Brimble, P. Young, P. Harris, 2015, Biopolymers.

An improved procedure for the preparation of aminomethyl polystyrene resin and its use in solid phase (peptide) synthesis

Sung‐Hyun Yang, M. Brimble, P. Harris, 2011 .

The Synthesis of Phosphopeptides Using Microwave-assisted Solid Phase Peptide Synthesis

M. Brimble, P. Harris, Geoffrey M. Williams, 2008, International Journal of Peptide Research and Therapeutics.

Engineering a stable complex of ERp44 with a designed peptide ligand for analyzing the mode of interaction of ERp44 with its clients

A. Mitra, M. Radjainia, M. Brimble, 2021, Peptide Science.

Functionalization of Alkylalkoxysilanes. Studies Towards Annulations of Diterpenoids.

P. Harris, P. D. Woodgate, 2000 .

A comparison of Boc and Fmoc SPPS strategies for the preparation of C-terminal peptide α-thiolesters: NY-ESO-1 ³⁹Cys-⁶⁸Ala-COSR.

M. Brimble, P. Harris, 2013, Biopolymers.

Toward the total chemical synthesis of the cancer protein NY-ESO-1.

M. Brimble, P. Harris, 2010, Biopolymers.

Synthesis of an Arginine Tagged [Cys155-Arg180] Fragment of NY-ESO-1: Elimination of an Undesired By-product Using ‘In House’ Resins

M. Brimble, P. Harris, 2009 .

A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry.

S. Kent, Dong Jun Lee, M. Brimble, 2009, Organic letters.

Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs

M. Brimble, A. Cameron, P. Harris, 2020, Frontiers in Chemistry.

Total Synthesis of Novel Antimicrobial β-Hairpin Capitellacin Via Rapid Flow-Based SPPS Assembly and Regioselective On-Resin Disulfide Cyclisation

M. Brimble, A. Cameron, P. Harris, 2021, International Journal of Peptide Research and Therapeutics.

Synthesis of paenipeptin C' analogues employing solution-phase CLipPA chemistry.

M. Brimble, G. Cook, P. Harris, 2020, Organic & biomolecular chemistry.

Synthesis of Lipopeptides by CLipPA Chemistry.

M. Brimble, P. Harris, Yann O Hermant, 2021, Methods in molecular biology.

Replacement of the Acrid tert -Butylthiol and an Improved Isolation Protocol for Cysteine Lipidation on a Peptide or Amino Acid (CLipPA)

Sung‐Hyun Yang, M. Brimble, P. Harris, 2020 .

Direct peptide lipidation through thiol-ene coupling enables rapid synthesis and evaluation of self-adjuvanting vaccine candidates.

M. Brimble, P. Dunbar, P. Harris, 2013, Angewandte Chemie.

Investigations of the key macrolactamisation step in the synthesis of cyclic tetrapeptide pseudoxylallemycin A.

M. Brimble, A. Cameron, P. Harris, 2019, Organic & biomolecular chemistry.

A versatile Boc solid phase synthesis of daptomycin and analogues using site specific, on-resin ozonolysis to install the kynurenine residue.

Sung‐Hyun Yang, M. Brimble, P. Harris, 2019, Chemistry.

Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin.

D. Raleigh, C. Reynolds, A. Pioszak, 2018, ACS pharmacology & translational science.

Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY‐ESO‐1 enabled by kinetically controlled ligation and pseudoprolines

M. Brimble, P. Harris, 2015, Biopolymers.

An Insight into FDA Approved Antibody-Drug Conjugates for Cancer Therapy

M. Brimble, P. Harris, I. Kavianinia, 2021, Molecules.

Plasma cyclic glycine proline/IGF‐1 ratio predicts clinical outcome and recovery in stroke patients

R. Krishnamurthi, P. Barber, P. Harris, 2019, Annals of clinical and translational neurology.

Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor

A. Pioszak, M. Brimble, R. Bill, 2015, Molecular cell.

Alanine scan-guided synthesis and biological evaluation of analogues of culicinin D, a potent anticancer peptaibol.

J. Smaill, M. Brimble, P. Harris, 2020, Bioorganic & medicinal chemistry letters.

Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides.

G. Cooper, M. Brimble, P. Harris, 2012, Organic letters.

Receptor Activity Modifying Proteins Have Limited Effects on the Class B G Protein-Coupled Receptor Calcitonin Receptor-Like Receptor Stalk.

Sung‐Hyun Yang, M. Brimble, D. Hay, 2018, Biochemistry.

Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization

E. Baker, M. Brimble, P. Young, 2016, IUCrJ.

Receptor Activity-modifying Proteins 2 and 3 Generate Adrenomedullin Receptor Subtypes with Distinct Molecular Properties

Christopher A. Reynolds, Margaret A. Brimble, Alex C. Conner, 2016, The Journal of Biological Chemistry.

Efficient synthesis and characterisation of the amyloid beta peptide, Aβ1-42, using a double linker system.

M. Brimble, P. Harris, Johanes K. Kasim, 2018, Organic & biomolecular chemistry.

On-resin Preparation of Allenamidyl Peptides: a Versatile Chemoselective Conjugation and Intramolecular Cyclisation Tool.

M. Brimble, A. Cameron, P. Harris, 2020, Angewandte Chemie.

Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors.

P. Sexton, Sung‐Hyun Yang, M. Brimble, 2020, ACS pharmacology & translational science.

Total Synthesis of Allene-Containing Cyclic Tetrapeptide Pseudoxylallemycin C

M. Brimble, A. Cameron, P. Harris, 2020, Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry.

Chemical synthesis of a masked analogue of the fish antifreeze potentiating protein (AFPP).

Sung‐Hyun Yang, M. Brimble, A. Devries, 2013, Organic & biomolecular chemistry.

Plant antimicrobial peptides snakin-1 and snakin-2: chemical synthesis and insights into the disulfide connectivity.

Sung‐Hyun Yang, M. Brimble, P. Harris, 2014, Chemistry.

Characterizing the mode of action of extracellular Connexin43 channel blocking mimetic peptides in an in vitro ischemia injury model.

C. Green, M. Brimble, S. O'Carroll, 2017, Biochimica et biophysica acta. General subjects.

Chemical Synthesis of A Pore‐Forming Antimicrobial Protein, Caenopore‐5, by Using Native Chemical Ligation at a Glu‐Cys Site

M. Brimble, G. Cook, Kiel Hards, 2015, Chembiochem : a European journal of chemical biology.

The Chemical Synthesis of the Collagenous Domain of the Hormone Adiponectin

M. Brimble, P. Harris, 2012, International Journal of Peptide Research and Therapeutics.

Synthesis of a C-Terminal Thioester Derivative of the Lipopeptide Pam2CSKKKKG Using Fmoc SPPS

S. Kent, M. Brimble, R. Dunbar, 2007 .

Variable-length Ester-based Staples for α-Helical Peptides Using A Double Thiol-ene Reaction.

M. Brimble, J. Flanagan, P. Harris, 2020, Chemistry.

Synthesis and incorporation of an advanced lipid peroxidation end-product building block into collagen mimetic peptides.

R. Dobson, Sung‐Hyun Yang, M. Brimble, 2017, Chemical communications.

Cyclic glycine-proline administration normalizes high-fat diet-induced synaptophysin expression in obese rats

M. Vickers, P. Harris, J. Guan, 2019, Neuropeptides.

Physicochemical studies on the copper(II) binding by glycated collagen telopeptides.

G. Cooper, M. Brimble, G. Miskelly, 2015, Organic & biomolecular chemistry.

Synthesis and Self-Assembly of a Peptide)Amphiphile as a Drug Delivery Vehicle

Oliver E. Hutt, Sung‐Hyun Yang, M. Brimble, 2013 .

The role for cyclic Glycine-Proline, a biological regulator of insulin-like growth factor-1 in pregnancy-related obesity and weight changes.

E. Mitchell, M. Brimble, P. Shorten, 2018, Journal of Biological Regulators and Homeostatic Agents.

Flow-Based Fmoc-SPPS Preparation and SAR Study of Cathelicidin-PY Reveals Selective Antimicrobial Activity

Sung‐Hyun Yang, M. Brimble, A. Cameron, 2023, Molecules.

A review of the molecular conformations of melatonin ligands at the melatonin receptor

P. Harris, H. Hügel, Paul W.R. Harris, 2002 .

Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts.

G. Cooper, M. Brimble, P. Harris, 2014, Chemical Communications.

Fourth-Generation Analogues of the Anticancer Peptaibol Culicinin D: Probing the Effects of Hydrophobicity and Halogenation on Cytotoxicity

J. Smaill, M. Brimble, P. Harris, 2021, Synthesis.

G. Cooper, M. Brimble, D. Hay, 2015, Physiological reports.

1 Desacetyl-α-melanocyte stimulating hormone and α-melanocyte 1 stimulating hormone are required to regulate energy balance 2 3

J. Elmquist, C. Buchanan, A. Coll, 2017 .

A novel tyrosine hyperoxidation enables selective peptide cleavage

M. Brimble, P. Harris, Ivanhoe K. H. Leung, 2022, Chemical Science.

On-Resin Conjugation of the Ruthenium Anticancer Agent Plecstatin-1 to Peptide Vectors.

M. Brimble, S. Jamieson, P. Harris, 2023, Inorganic chemistry.

Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02170h

E. J. Aitken, Robert A Keyzers, M. Brimble, 2018, Chemical science.

Site-specific cross-linking of collagen peptides by lysyl advanced glycation endproducts.

M. Brimble, P. Harris, Meder Kamalov, 2014, Chemical communications.

An investigation of the role of the adiponectin variable domain on the stability of the collagen‐like domain

A. Mitra, M. Radjainia, M. Brimble, 2014, Biopolymers.

A Single Pseudoproline and Microwave Solid Phase Peptide Synthesis Facilitates an Efficient Synthesis of Human Amylin 1–37

M. Brimble, D. Hay, P. Harris, 2013, International Journal of Peptide Research and Therapeutics.

Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia–ischemia in adult rats

P. Gluckman, M. Brimble, Jingyuan Wen, 2007, Neuropharmacology.

The Antimicrobial Peptide Capitellacin: Chemical Synthesis of Analogues to Probe the Role of Disulphide Bridges and Their Replacement with Vinyl Sulphides

M. Brimble, A. Cameron, P. Harris, 2024, Antibiotics.

Total synthesis of the proposed structure of talarolide A.

M. Brimble, P. Harris, Ivanhoe K. H. Leung, 2018, Organic & biomolecular chemistry.

“CLipP”ing on lipids to generate antibacterial lipopeptides

Jane R. Allison, M. Brimble, S. Swift, 2020, Chemical science.

A. Mitra, M. Radjainia, P. Harris, 2017 .

A synthetic approach to ‘click’ neoglycoprotein analogues of EPO employing one-pot native chemical ligation and CuAAC chemistry

M. Brimble, A. Cameron, P. Harris, 2018, Chemical science.