Suman Nag

发表

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human β-cardiac myosin motor function

L. Leinwand, J. Spudich, S. Sutton, 2013, Proceedings of the National Academy of Sciences.

Improved Inhibitory and Absorption, Distribution, Metabolism, Excretion, and Toxicology (ADMET) Properties of Blebbistatin Derivatives Indicate That Blebbistatin Scaffold Is Ideal for drug Development Targeting Myosin-2

Z. Borhegyi, Anna Á. Rauscher, A. Málnási-Csizmadia, 2021, The Journal of Pharmacology and Experimental Therapeutics.

tropomyosinsand nemaline myopathy mutant Divergent abnormal muscle relaxation by hypertrophic

J. Spudich, R. Vandenboom, R. Sowdhamini, 2015 .

The Myosin Family of Mechanoenzymes: From Mechanisms to Therapeutic Approaches.

J. Spudich, Darshan V Trivedi, K. Ruppel, 2020, Annual review of biochemistry.

A folding transition underlies the emergence of membrane affinity in amyloid-β.

E. Haas, E. Lerner, D. Bhowmik, 2013, Physical chemistry chemical physics : PCCP.

A small-molecule myosin inhibitor as a targeted multi-stage antimalarial

Paul V. Ruijgrok, E. Winzeler, J. Spudich, 2022, bioRxiv.

Mechanistic Heterogeneity in Contractile Properties of α-Tropomyosin (TPM1) Mutants Associated with Inherited Cardiomyopathies*

K. Thangaraj, J. Spudich, R. Sowdhamini, 2014, The Journal of Biological Chemistry.

Effects of Troponin T Cardiomyopathy Mutations on the Calcium Sensitivity of the Regulated Thin Filament and the Actomyosin Cross-Bridge Kinetics of Human β-Cardiac Myosin

J. Spudich, Susan M. Miller, S. Sutton, 2013, PloS one.

Single Molecule In Vivo Analysis of Toll-Like Receptor 9 and CpG DNA Interaction

J. Irudayaraj, Pierre-Alexandre Vidi, Suman Nag, 2011, PloS one.

Improved inhibitory and ADMET properties of blebbistatin derivatives indicate that blebbistatin scaffold is ideal for drug development targeting myosin-2

Z. Borhegyi, Anna Á. Rauscher, A. Málnási-Csizmadia, 2020 .

Harmonic force spectroscopy measures load-dependent kinetics of individual human β-cardiac myosin molecules

Christian L. Vestergaard, H. Flyvbjerg, J. Spudich, 2015, Nature Communications.

Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

M. Kombrabail, V. Sreenivasan, S. Maiti, 2011, The Journal of Biological Chemistry.

Intermolecular association provides specific optical and NMR signatures for serotonin at intravesicular concentrations.

S. Maiti, Suman Nag, P. Madhu, 2008, Biophysical journal.

Mechanisms of apoptosis in Crustacea: what conditions induce versus suppress cell death?

S. Hand, M. Menze, Suman Nag, 2010, Apoptosis.

Synthetic thick filaments: A new avenue for better understanding the myosin super-relaxed state in healthy, diseased, and mavacamten-treated cardiac systems

Sampath K Gollapudi, Suman Nag, Ming Yu, 2020, The Journal of biological chemistry.

CONSERVED INTERACTIONS IN CARDIAC SYNTHETIC THICK FILAMENTS DIFFERENTLY AFFECT MYOSIN SUPER-RELAXED STATE IN HEALTHY, DISEASE AND MAVACAMTEN-TREATED MODELS

Sampath K Gollapudi, Suman Nag, 2020, bioRxiv.

Label-free dopamine imaging in live rat brain slices.

S. Maiti, Arkarup Banerjee, Umakanta Tripathy, 2014, ACS chemical neuroscience.

Contractility parameters of human b-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function

L. Leinwand, J. Spudich, S. Langer, 2015 .

Beyond the myosin mesa: a potential unifying hypothesis on the underlying molecular basis of hyper-contractility caused by a majority of hypertrophic cardiomyopathy mutations

J. Spudich, S. Sutton, K. Ruppel, 2016, bioRxiv.

To lie or not to lie: Super-relaxing with myosins

Suman Nag, Darshan V. Trivedi, 2021, eLife.

A high-resolution large area serotonin map of a live rat brain section

S. Maiti, Suman Nag, S. Kaushalya, 2008, Neuroreport.

Cardiac myosin filaments are directly regulated by calcium

T. Irving, Suman Nag, Weikang Ma, 2022, bioRxiv.

Measurement of the attachment and assembly of small amyloid-β oligomers on live cell membranes at physiological concentrations using single-molecule tools.

J. Irudayaraj, S. Maiti, Suman Nag, 2010, Biophysical journal.

The basic structural motif and major biophysical properties of Amyloid-β are encoded in the fragment 18–35

Neelanjana Sengupta, D. Bhowmik, S. Maiti, 2013 .

Ultracompact alignment-free single molecule fluorescence device with a foldable light path.

Sudipta Maiti, Jenu V Chacko, Varun K A Sreenivasan, 2011, Journal of biomedical optics.

Effects of hypertrophic and dilated cardiomyopathy mutations on power output by human β-cardiac myosin

J. Spudich, A. Adhikari, S. Bartholomew, 2016, Journal of Experimental Biology.

On the stability of the soluble amyloid aggregates.

S. Maiti, P. Sengupta, Suman Nag, 2009, Biophysical journal.

Establishing disease causality for a novel gene variant in familial dilated cardiomyopathy using a functional in-vitro assay of regulated thin filaments and human cardiac myosin

E. Ashley, J. Spudich, Susan M. Miller, 2015, BMC Medical Genetics.

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

J. Spudich, A. Adhikari, S. Sutton, 2017, Nature Structural &Molecular Biology.

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors

S. Mijailovich, T. Irving, C. D. del Rio, 2023, bioRxiv : the preprint server for biology.

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors

S. Mijailovich, T. Irving, Sampath K Gollapudi, 2023, bioRxiv.

TWO CLASSES OF MYOSIN INHIBITORS, BLEBBISTATIN AND MAVACAMTEN, STABILIZE β-CARDIAC MYOSIN IN DIFFERENT STRUCTURAL AND FUNCTIONAL STATES

T. Irving, S. Chakravarthy, S. Langer, 2020, bioRxiv.

Nag 1..16

L. Leinwand, J. Spudich, S. Langer, 2015 .

Spontaneous formation of a protein corona prevents the loss of quantum dot fluorescence in physiological buffers

S. Maiti, Suman Nag, B. Sahoo, 2007 .

Serotonin: multiphoton imaging and relevant spectral data

Sudipta Maiti, Sanjeev Kumar Kaushalya, Suman Nag, 2008, SPIE BiOS.

Protein aggregation probed by two-photon fluorescence correlation spectroscopy of native tryptophan.

S. Maiti, Suman Nag, J. Balaji, 2008, The Journal of chemical physics.

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors

S. Mijailovich, T. Irving, C. D. del Rio, 2023, bioRxiv.

Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients.

J. Spudich, C. D. del Rio, Sampath K Gollapudi, 2023, Science advances.

Contractility parameters of human b-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function

L. Leinwand, J. Spudich, S. Langer, 2015 .

Nature of the Amyloid-β Monomer and the Monomer-Oligomer Equilibrium

M. Kombrabail, V. Sreenivasan, S. Maiti, 2011, The Journal of Biological Chemistry.

Link to record in KAR

L. Leinwand, J. Spudich, S. Langer, 2022 .

Mechanistic Heterogeneity in Contractile Properties of (cid:2) -Tropomyosin ( TPM1 ) Mutants Associated with Inherited Cardiomyopathies *

S. Mukherjee, R. Sommese, Suman Nag, 2015 .