D. Freedberg

发表

Flap opening and dimer-interface flexibility in the free and inhibitor-bound HIV protease, and their implications for function.

J. Louis, D. Torchia, R. Ishima, 1999, Structure.

Data processing in NMR relaxometry using the matrix pencil.

J. Seymour, D. Freedberg, S.N. Fricke, 2020, Journal of magnetic resonance.

Solution NMR evidence that the HIV-1 protease catalytic aspartyl groups have different ionization states in the complex formed with the asymmetric drug KNI-272.

T. Yamazaki, D. Torchia, P. Wingfield, 1996, Biochemistry.

Glycosylation States on Intact Proteins Determined by NMR Spectroscopy

Lai-Xi Wang, D. Freedberg, J. Orwenyo, 2021, Molecules.

A combined NMR, MD and DFT conformational analysis of 9-O-acetyl sialic acid-containing GM3 ganglioside glycan and its 9-N-acetyl mimic.

Lee‐Ping Wang, Hai Yu, D. Freedberg, 2020, Glycobiology.

Probing the interior of fullerenes by 3He NMR spectroscopy of endohedral 3He@C60 and 3He@C70

M. Saunders, H. Jiménez-Vázquez, F. Anet, 1994, Nature.

Effects of codon optimization on coagulation factor IX translation and structure: Implications for protein and gene therapies

Michael DiCuccio, A. Komar, N. Janjić, 2019, Scientific Reports.

Single synonymous mutation in factor IX alters protein properties and underlies haemophilia B

A. Komar, C. Kimchi-Sarfaty, Z. Sauna, 2016, Journal of Medical Genetics.

Synthesis and X-ray structure of a Diels-Alder adduct of C60

Y. Rubin, C. Yeretzian, D. Freedberg, 1993 .

Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics

Ryan M. Evans, Anthony J. Kearsley, Robert G. Brinson, 2018, mAbs.

Sensitivity enhancement of homonuclear multidimensional NMR correlations for labile sites in proteins, polysaccharides, and nucleic acids

H. Schwalbe, E. Kupče, L. Frydman, 2020, Nature Communications.

Size-Controlled Chemoenzymatic Synthesis of Homogeneous Oligosaccharides of Neisseria meningitidis W Capsular Polysaccharide.

Hai Yu, D. Freedberg, Xi Chen, 2020, ACS catalysis.

Biological activities of melanotropic peptide fatty acid conjugates.

V. Hruby, D. Freedberg, M. Hadley, 1991, Pigment cell research.

Structural, functional, and immunogenicity implications of F9 gene recoding

A. Komar, C. Kimchi-Sarfaty, Z. Sauna, 2022, Blood advances.

Conjugates of Group A and W135 Capsular Polysaccharides of Neisseria meningitidis Bound to Recombinant Staphylococcus aureus Enterotoxin C1: Preparation, Physicochemical Characterization, and Immunological Properties in Mice

J. Shiloach, B. Coxon, R. Schneerson, 2005, Infection and Immunity.

3HE NMR : A POWERFUL NEW TOOL FOR FOLLOWING FULLERENE CHEMISTRY

M. Saunders, H. Jiménez-Vázquez, F. Anet, 1994 .

Chemical structure and genetic organization of the E. coli O6:K15 capsular polysaccharide

H. Azurmendi, D. Freedberg, W. Vann, 2020, Scientific Reports.

Uncovering Nonconventional and Conventional Hydrogen Bonds in Oligosaccharides through NMR Experiments and Molecular Modeling: Application to Sialyl Lewis-X.

H. Azurmendi, M. Frank, D. Freedberg, 2015, Journal of the American Chemical Society.

Hadamard magnetization transfers achieve dramatic sensitivity enhancements in homonuclear multidimensional NMR correlations of labile sites in proteins, polysaccharides and nucleic acids

Maryland., Research, J. W. Goethe-University, 2020, 2004.13063.

Evidence for helical structure in a tetramer of α2-8 sialic acid: unveiling a structural antigen.

J. Shiloach, D. Freedberg, M. Battistel, 2012, Journal of the American Chemical Society.

Synthesis and Physicochemical Characterization of D-Tagatose-1-Phosphate: The Substrate of the Tagatose-1-Phosphate Kinase in the Phosphotransferase System-Mediated D-Tagatose Catabolic Pathway of Bacillus licheniformis

B. Joris, M. Galleni, M. Delmarcelle, 2015, Journal of Molecular Microbiology and Biotechnology.

Flexibility and Function in HIV Protease: Dynamics of the HIV-1 Protease Bound to the Asymmetric Inhibitor Kynostatin 272 (KNI-272)

Yun-Xing Wang, D. Torchia, P. Wingfield, 1998 .

Lyophilization induces physicochemical alterations in cryptococcal exopolysaccharide

A. Casadevall, R. Stark, D. Freedberg, 2022, Carbohydrate polymers.

Lyophilization induces alterations in cryptococcal exopolysaccharide resulting in reduced antibody binding

A. Casadevall, R. Stark, D. Freedberg, 2022, bioRxiv.

On the Potential Energy Surface for Ring Inversion in Cyclohexene and Related Molecules

K. Houk, F. Anet, D. Freedberg, 1992 .

Carbohydrate structure from NMR residual dipolar couplings : Is there a correlation between lactose's anomeric configuration and its three-dimensional structure?

R. Venable, D. Freedberg, Scott E Norris, 2006 .

NMR of glycans: shedding new light on old problems.

H. Azurmendi, D. Freedberg, M. Battistel, 2014, Progress in nuclear magnetic resonance spectroscopy.

Stereochemistry of the Thermal Isomerization of Vinylcyclopropane to Cyclopentene

F. Anet, D. Freedberg, J. Baldwin, 1994 .

Accurate determinations of one-bond 13C-13C couplings in 13C-labeled carbohydrates.

H. Azurmendi, D. Freedberg, 2013, Journal of magnetic resonance.

The utility of residual dipolar couplings in detecting motion in carbohydrates: application to sucrose.

F. Delaglio, R. Venable, D. Freedberg, 2005, Carbohydrate research.

Glycan OH Exchange Rate Determination in Aqueous Solution: Seeking Evidence for Transient Hydrogen Bonds.

H. Azurmendi, D. Freedberg, M. Battistel, 2017, The journal of physical chemistry. B.

Extracellular structure of polysialic acid explored by on cell solution NMR

J. Shiloach, H. Azurmendi, J. Vionnet, 2007, Proceedings of the National Academy of Sciences.

Escherichia coli K1 polysialic acid O-acetyltransferase gene, neuO, and the mechanism of capsule form variation involving a mobile contingency locus.

E. Vimr, D. Freedberg, Eric L. Deszo, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Utility of coupled-HSQC experiments in the intact structural elucidation of three complex saponins from Blighia sapida.

B. Coxon, E. Kennelly, D. Freedberg, 2011, Carbohydrate research.

More accurate 1J(CH) coupling measurement in the presence of 3J(HH) strong coupling in natural abundance.

C. Rademacher, H. van Ingen, D. Freedberg, 2012, Journal of magnetic resonance.

Phospho-beta-glucosidase from Fusobacterium mortiferum: purification, cloning, and inactivation by 6-phosphoglucono-delta-lactone

J. Thompson, D. Freedberg, C. Bouma, 1997, Journal of bacteriology.

Direct evidence for hydrogen bonding in glycans: a combined NMR and molecular dynamics study.

G. Widmalm, R. Pendrill, D. Freedberg, 2013, The journal of physical chemistry. B.

Live cell NMR.

D. Freedberg, Philipp Selenko, 2014, Annual review of biophysics.

NMR profiling of biomolecules at natural abundance using 2D 1H-15N and 1H-13C multiplicity-separated (MS) HSQC spectra.

Kang Chen, D. Keire, D. Freedberg, 2015, Journal of magnetic resonance.

Release of DNA Oligonucleotides and Their Conjugates from Controlled‐Pore Glass Under Thermolytic Conditions

Jon S. Kauffman, S. Beaucage, R. Duff, 2008, Current protocols in nucleic acid chemistry.

Thermolytic release of covalently linked DNA oligonucleotides and their conjugates from controlled-pore glass at near neutral pH.

Jon S. Kauffman, S. Beaucage, R. Duff, 2008, Bioconjugate chemistry.

In vitro sulfotransferase activity of NodH, a nodulation protein of Rhizobium meliloti required for host-specific nodulation

D. Sutherlin, D. Ehrhardt, K. Faull, 1995, Journal of bacteriology.

Structural and functional characterization of glutaraldehyde-polymerized bovine hemoglobin and its isolated fractions.

P. Buehler, A. Alayash, D. Freedberg, 2005, Analytical chemistry.

Glycosylhydrolases Assignment to the Unusual Family 4 of ofEscherichia coli: Characterization and Cellobiose-6-Phosphate Hydrolase (CelF)

B. Hall, S. Ruvinov, D. Freedberg, 2013 .

Cellobiose-6-Phosphate Hydrolase (CelF) ofEscherichia coli: Characterization and Assignment to the Unusual Family 4 of Glycosylhydrolases

B. Hall, S. Ruvinov, D. Freedberg, 1999, Journal of bacteriology.

NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B

Yawen Bai, L. Kay, Carl Wu, 2008, Nature Structural &Molecular Biology.

Rapid structural fluctuations of the free HIV protease flaps in solution: Relationship to crystal structures and comparison with predictions of dynamics calculations

Rieko Ishima, J. Louis, Yun-Xing Wang, 2002, Protein science : a publication of the Protein Society.

Dispersing the crowd: Adopting 13C direct detection for glycans.

D. Freedberg, M. Battistel, 2020, Journal of magnetic resonance.

NMR detection and characterization of sialylated glycoproteins and cell surface polysaccharides

J. Prestegard, A. Barb, D. Freedberg, 2011, Journal of biomolecular NMR.

Application of 2D‐NMR with room temperature NMR probes for the assessment of the higher order structure of filgrastim

Kristie M. Adams, Robert G. Brinson, Kang Chen, 2017, Journal of pharmaceutical and biomedical analysis.

Deuterium conformational equilibrium isotope effects in 1,3,5-cycloheptatriene-7-d

F. Anet, D. Freedberg, M. Kopelevich, 2001 .

Sialo-CEST: chemical exchange saturation transfer NMR of oligo- and poly-sialic acids and the assignment of their hydroxyl groups using selective- and HSQC-TOCSY.

G. Navon, D. Freedberg, M. Battistel, 2014, Carbohydrate research.

Reversible O-Acetyl Migration within the Sialic Acid Side Chain and Its Influence on Protein Recognition.

A. Varki, Lee‐Ping Wang, C. Parrish, 2021, ACS chemical biology.

Glycan Stability and Flexibility: Thermodynamic and Kinetic Characterization of Nonconventional Hydrogen Bonding in Lewis Antigens

H. Azurmendi, D. Freedberg, M. Battistel, 2023, Journal of the American Chemical Society.

The Incorporation of Labile Protons into Multidimensional NMR Analyses: Glycan Structures Revisited

L. Frydman, H. Azurmendi, D. Freedberg, 2021, Journal of the American Chemical Society.

Solution NMR Structural Studies of Glycans

D. Freedberg, Jeahoo Kwon, 2019, Israel Journal of Chemistry.

One- and Two-Dimensional NMR Techniques for Biopharmaceuticals

Yves Aubin, Daron I. Freedberg, David A. Keire, 2015 .

Iron and Zinc Regulate Expression of a Putative ABC Metal Transporter in Corynebacterium diphtheriae

M. Schmitt, D. Freedberg, M. Battistel, 2018, Journal of bacteriology.

Bound Water Molecules at the Interface between the HIV-1 Protease and a Potent Inhibitor, KNI-272, Determined by NMR

T. Bhat, Yun-Xing Wang, D. Torchia, 1996 .

Letter to the Editor: Sequential resonance assignments of the extracellular ligand binding domain of the human TGF-β type II receptor

A. Hinck, S. Deep, C. Hinck, 2000 .

Constant time INEPT CT-HSQC (CTi-CT-HSQC) - A new NMR method to measure accurate one-bond J and RDCs with strong 1H-1H couplings in natural abundance.

D. Freedberg, Bingwu Yu, Hugo van Ingen, 2013, Journal of magnetic resonance.

Thermolytic release of covalently linked DNA oligonucleotides and their conjugates from controlled-pore glass at near neutral pH.

Jon S. Kauffman, S. Beaucage, R. Duff, 2008, Bioconjugate chemistry.