Adrian Westhaus

发表

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2

Claus V. Hallwirth, I. Alexander, M. Agbandje-McKenna, 2020, Molecular therapy. Methods & clinical development.

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8

Laurence O. W. Wilson, I. Alexander, A. Thrasher, 2021, Molecular therapy. Methods & clinical development.

Restoring the natural tropism of AAV2 vectors for human liver

Claus V. Hallwirth, I. Alexander, M. Agbandje-McKenna, 2020, Science Translational Medicine.

High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction

I. Alexander, A. Gonzalez-Cordero, A. Thrasher, 2020, Human gene therapy.

AAV-p40 Bioengineering Platform for Variant Selection Based on Transgene Expression

I. Alexander, A. Gonzalez-Cordero, A. Thrasher, 2022, Human gene therapy.

Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors

Laurence O. W. Wilson, I. Alexander, G. González-Aseguinolaza, 2022, bioRxiv.

Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality

Claus V. Hallwirth, I. Alexander, H. Nakai, 2018, Molecular therapy. Methods & clinical development.

The Antidiabetic Drug Metformin Stimulates Glycolytic Lactate Production in Cultured Primary Rat Astrocytes

R. Dringen, Adrian Westhaus, Eva-Maria Blumrich, 2015, Neurochemical Research.

Pre-arrayed Pan-AAV Peptide Display Libraries for Rapid Single-Round Screening.

H. Erfle, D. Grimm, Nina Beil, 2020, Molecular therapy : the journal of the American Society of Gene Therapy.

In Search of Adeno-Associated Virus Vectors With Enhanced Cardiac Tropism for Gene Therapy.

E. Kizana, I. Alexander, Adrian Westhaus, 2023, Heart, lung & circulation.

Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation

I. Alexander, G. González-Aseguinolaza, Erhua Zhu, 2023, bioRxiv.

AAV capsid bioengineering in primary human retina models

Grace E. Lidgerwood, A. Gonzalez-Cordero, A. Thrasher, 2023, Scientific reports.

Assessment of Pre-Clinical Liver Models Based on Their Ability to Predict the Liver-Tropism of Adeno-Associated Virus Vectors

M. Liebert, A. Thrasher, Erhua Zhu, 2022 .

ADEVO: Proof-of-concept of Adenovirus Directed EVOlution by random peptide display on the fiber knob

Wenli Zhang, A. Ehrhardt, Marti Cabanes-Creus, 2023, bioRxiv.

Identifying adeno-associated virus (AAV) vectors that efficiently target high grade glioma cells, for in vitro monitoring of temporal cell responses.

Adrian Westhaus, L. Lisowski, F. A. Sarker, 2024, FEBS open bio.