G. Logan

发表

Adeno-associated virus vector gene delivery elevates Factor I levels and down-regulates the complement alternative pathway in vivo.

P. Lachmann, I. Alexander, T. Malik, 2021, Human gene therapy.

Restoring the natural tropism of AAV2 vectors for human liver

Claus V. Hallwirth, I. Alexander, M. Agbandje-McKenna, 2020, Science Translational Medicine.

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice

I. Alexander, N. Nassif, A. Simpson, 2020, Cells.

Gene delivery to the juvenile mouse liver using AAV2/8 vectors.

I. Alexander, G. Logan, S. Cunningham, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Human induced pluripotent stem cells derived under feeder-free conditions display unique cell cycle and DNA replication gene profiles.

Perminder S Sachdev, P. Sachdev, I. Alexander, 2012, Stem cells and development.

Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.

I. Alexander, S. Alexander, T. Sparwasser, 2018, JCI insight.

CD4 expression on EL4 cells as an epiphenomenon of retroviral transduction and selection

I. Alexander, S. Alexander, G. Logan, 2004, Immunology and cell biology.

Adeno-associated virus-mediated rescue of neonatal lethality in argininosuccinate synthetase-deficient mice.

P. Kuchel, I. Alexander, K. Carpenter, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Gene therapy in transplantation.

I. Alexander, G. Bishop, A. Sharland, 2009, Transplantation reviews.

Antigen fusion with C3d3 augments or inhibits humoral immunity to AAV genetic vaccines in a transgene‐dependent manner

R. Coppel, I. Alexander, G. Logan, 2010, Immunology and cell biology.

Identification of a dynamic intracellular reservoir of CD86 protein in peripheral blood monocytes that is not associated with the Golgi complex.

I. Alexander, C. Smyth, G. Logan, 1998, Journal of immunology.

ComplexMonocytes That Is Not Associated with the Golgi Reservoir of CD86 Protein in Peripheral Blood Identification of a Dynamic Intracellular

I. Alexander, C. Smyth, G. Logan, 1998 .

Human fibroblasts transduced with CD80 or CD86 efficiently trans-costimulate CD4+ and CD8+ T lymphocytes in HLA-restricted reactions: implications for immune augmentation cancer therapy and autoimmunity.

I. Alexander, J. Lees, G. Logan, 1999, Journal of immunology.

Immune Augmentation Cancer Therapy and HLA-Restricted Reactions : Implications for T Lymphocytes in + and CD 8 +-Costimulate CD 4 trans or CD 86 Efficiently Human Fibroblasts Transduced with CD 80

I. Alexander, J. Lees, G. Logan, 1999 .

Performance of Cardiotropic rAAV Vectors Is Dependent on Production Method

E. Kizana, I. Alexander, James J. H. Chong, 2022, Viruses.

Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus

I. Alexander, C. Kok, G. Logan, 2015, Gene Therapy.

Antigen-specific humoral tolerance or immune augmentation induced by intramuscular delivery of adeno-associated viruses encoding CTLA4-Ig-antigen fusion molecules

R. Coppel, I. Alexander, G. Logan, 2009, Gene Therapy.

( IL )-7 and IL-15 receptors c expression differentially affects signaling via the interleukin γ Limiting

I. Alexander, C. Deakin, C. Smyth, 2007 .

Robust anti-tumor immunity and memory in Rag-1-deficient mice following adoptive transfer of cytokine-primed splenocytes and tumor CD80 expression

I. Alexander, S. Alexander, G. Zhang, 2007, Cancer Immunology, Immunotherapy.

Conversion of the liver into a biofactory for DNaseI using adeno-associated virus vector gene transfer reduces neutrophil extracellular traps in a model of Systemic Lupus Erythematosus.

P. Lachmann, I. Alexander, S. Holdsworth, 2022, Human gene therapy.

Differential subcellular localization of CD86 in human PBMC-derived macrophages and DCs, and ultrastructural characterization by immuno-electron microscopy.

I. Alexander, R. Boadle, C. Smyth, 2004, International immunology.

HeLa cells cocultured with peripheral blood lymphocytes acquire an immuno‐inhibitory phenotype through up‐regulation of indoleamine 2,3‐dioxygenase activity

I. Alexander, C. Smyth, G. Logan, 2002, Immunology.

Exploiting the unique regenerative capacity of the liver to underpin cell and gene therapy strategies for genetic and acquired liver disease.

I. Alexander, G. Yeoh, G. Logan, 2014, The international journal of biochemistry & cell biology.

The transcriptional and functional properties of mouse epiblast stem cells resemble the anterior primitive streak.

Erdahl T. Teber, Oliver H. Tam, H. Pickett, 2014, Cell stem cell.

Identification of liver-specific enhancer–promoter activity in the 3′ untranslated region of the wild-type AAV2 genome

Claus V. Hallwirth, D. Russell, P. Tam, 2017, Nature Genetics.

Gain-of-function factor H–related 5 protein impairs glomerular complement regulation resulting in kidney damage

A. Bradley, I. Alexander, T. Malik, 2021, Proceedings of the National Academy of Sciences.

Limiting {gamma}c expression differentially affects signaling via the interleukin (IL)-7 and IL-15 receptors.

I. Alexander, C. Deakin, C. Smyth, 2007, Blood.

Potential of AAV vectors in the treatment of metabolic disease

J. Christodoulou, I. Alexander, G. Logan, 2008, Gene Therapy.

A novel intronic splice site deletion of the IL‐2 receptor common gamma chain results in expression of a dysfunctional protein and T‐cell‐positive X‐linked Severe combined immunodeficiency

J. Ziegler, T. Roscioli, I. Alexander, 2015, International journal of immunogenetics.

Adeno-associated virus vectors: immunobiology and potential use for immune modulation.

I. Alexander, G. Logan, 2012, Current gene therapy.

Efficient in vivo editing of OTC-deficient patient-derived primary human hepatocytes

Claus V. Hallwirth, H. Pickett, Michael Lee, 2019, JHEP reports.

AAV vectors encoding malarial antigens stimulate antigen-specific immunity but do not protect from parasite infection.

R. Coppel, I. Alexander, G. Logan, 2007, Vaccine.

A User's Guide to the Inverted Terminal Repeats (ITR) of Adeno-Associated Virus.

I. Alexander, L. Lisowski, G. Logan, 2019, Human gene therapy methods.

AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization

Zheng He, B. Bui, I. Alexander, 2018, Angiogenesis.

Liver-directed gene expression using recombinant AAV 2/8 vectors--a tolerogenic strategy for gene delivery?

I. Alexander, G. Logan, A. Bishop, 2010, Discovery medicine.

Altered Hippocampal and Striatal Expression of Endothelial Markers and VIP/PACAP Neuropeptides in a Mouse Model of Systemic Lupus Erythematosus

G. Musumeci, M. Mandwie, G. Logan, 2023, International journal of molecular sciences.

Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.

I. Alexander, S. Alexander, T. Sparwasser, 2018, JCI insight.

Structural and functional characterization of capsid binding by anti-AAV9 monoclonal antibodies from infants after SMA gene therapy.

I. Alexander, R. McKenna, J. Reed, 2023, Molecular Therapy.

Gene therapy in transplantation.

I. Alexander, G. Bishop, G. McCaughan, 2009, Transplantation reviews.

Recognition of Intact Donor Class I by Recipient CD8+ T Cells is Required for Tolerance Induction Following Liver-Directed Transgene Expression

I. Alexander, S. Alexander, T. Sparwasser, 2017 .