B. O'Brien

发表

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice

I. Alexander, N. Nassif, A. Simpson, 2020, Cells.

Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?

M. Labbate, Michael S. Johnson, B. Saunders, 2017, Parasites & Vectors.

Insulin Trafficking in a Glucose Responsive Engineered Human Liver Cell Line is Regulated by the Interaction of ATP-Sensitive Potassium Channels and Voltage-Gated Calcium Channels

Donald K. Martin, G. J. Liu, M. Lutherborrow, 2013 .

Long‐term reversal of diabetes in non‐obese diabetic mice by liver‐directed gene therapy

M. Wei, N. Nassif, A. Simpson, 2013, The journal of gene medicine.

Long-term correction of diabetes in rats after lentiviral hepatic insulin gene therapy

M. Wei, N. Nassif, A. Simpson, 2007, Diabetologia.

A helminth cathelicidin‐like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase

J. Dalton, C. Whitchurch, L. Turnbull, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A parasitic helminth-derived peptide that targets the macrophage lysosome is a novel therapeutic option for autoimmune disease.

J. Dalton, B. O'Brien, S. Donnelly, 2015, Immunobiology.

Pancreatic Transdifferentiation Using β-Cell Transcription Factors for Type 1 Diabetes Treatment

N. Nassif, A. Simpson, B. O'Brien, 2022, Cells.

Fasciola hepatica: the therapeutic potential of a worm secretome.

J. Dalton, B. O'Brien, M. Robinson, 2013, International journal for parasitology.

Secreted Proteins from the Helminth Fasciola hepatica Inhibit the Initiation of Autoreactive T Cell Responses and Prevent Diabetes in the NOD Mouse

J. Dalton, A. Simpson, B. O'Brien, 2014, PloS one.

Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line

N. Nassif, A. Simpson, Nichole Joachim, 2016, International journal of molecular sciences.

The immune modulatory peptide FhHDM‐1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

J. Dalton, A. Mansell, B. O'Brien, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Growth-promoting effect of Rh(D) antibody on human pancreatic islet cells.

A. Simpson, W. Hawthorne, P. O’Connell, 2008, The Journal of clinical endocrinology and metabolism.

Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells

N. Nassif, A. Simpson, B. Ren, 2019, Stem cells international.

Ex vivo expansion of murine MSC impairs transcription factor induced differentiation into 1 pancreatic β-cells 2

A. Simpson, B. Ren, B. O'Brien, 2018 .

Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells

N. Nassif, A. Simpson, F. Torpy, 2015, Molecular therapy. Methods & clinical development.

Pancreatic transdifferentiation in porcine liver following lentiviral delivery of human furin-cleavable insulin.

I. Alexander, N. Nassif, A. Simpson, 2013, Transplantation proceedings.

Discrimination of microsatellite repeat polymorphisms of the SLC11A1 promoter by melting curve analysis using the Eppendorf® Mastercycler ep realplex

N. Nassif, N. Archer, B. O'Brien, 2010 .

Neonatal Rats Exhibit a Predominantly Anti-Inflammatory Response following Spinal Cord Injury

B. O'Brien, C. Gorrie, Alison Ricafrente, 2021, Developmental Neuroscience.

The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus.

B. O'Brien, J. To, S. Donnelly, 2016, Journal of immunological methods.

A parasite-derived 68-mer peptide ameliorates autoimmune disease in murine models of Type 1 diabetes and multiple sclerosis

J. Dalton, A. Simpson, B. O'Brien, 2016, Scientific Reports.

Partial pancreatic transdifferentiation of primary human hepatocytes in the livers of a humanised mouse model

I. Alexander, N. Nassif, A. Simpson, 2018, The journal of gene medicine.

The helminth derived peptide FhHDM-1 redirects macrophage metabolism towards glutaminolysis to regulate the pro-inflammatory response

N. Snyder, B. O'Brien, S. Donnelly, 2023, Frontiers in Immunology.

Genetic variants of SLC 11 A 1 are associated with both autoimmune and infectious 1 diseases : systematic review and meta-analysis

N. Nassif, N. Archer, B. O'Brien, 2015 .

Association of SLC11A1 promoter polymorphisms with the incidence of autoimmune and inflammatory diseases: a meta-analysis.

N. Nassif, A. Simpson, N. Archer, 2008, Journal of autoimmunity.

Selection of reliable reference genes for the normalisation of gene expression levels following time course LPS stimulation of murine bone marrow derived macrophages

B. O'Brien, J. To, S. Donnelly, 2017, BMC Immunology.

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: An emerging therapeutic strategy for type 1 diabetes

B. O'Brien, S. Donnelly, Inah Camaya, 2022, Journal of diabetes.

The use of β-cell transcription factors in engineering artificial β cells from non-pancreatic tissue

A. Simpson, B. O'Brien, R. Martiniello-Wilks, 2014, Gene Therapy.

Genetic variants of SLC11A1 are associated with both autoimmune and infectious diseases: systematic review and meta-analysis

N. Nassif, N. Archer, B. O'Brien, 2015, Genes and Immunity.

How do parasitic worms prevent diabetes? An exploration of their influence on macrophage and β-cell crosstalk

B. O'Brien, S. Donnelly, Inah Camaya, 2023, Frontiers in endocrinology.

Targeting the master regulator mTOR: a new approach to prevent the neurological of consequences of parasitic infections?

M. Labbate, Michael S. Johnson, B. Saunders, 2017, Parasites & Vectors.

Exploring the role of macrophages in determining the pathogenesis of liver fluke infection

B. O'Brien, S. Donnelly, Susel Loli Quinteros, 2022, Parasitology.

Secreted Proteins from the Helminth Fasciola hepatica Inhibit the Initiation of Autoreactive T Cell Responses and Prevent Diabetes in the NOD Mouse

J. Dalton, A. Simpson, B. O'Brien, 2014, PloS one.