P. Guengerich

发表

P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.

R. Kim, F. Guengerich, C. Wandel, 1999, Cancer research.

Interaction of sulfaphenazole derivatives with human liver cytochromes P450 2C: molecular origin of the specific inhibitory effects of sulfaphenazole on CYP 2C9 and consequences for the substrate binding site topology of CYP 2C9.

D. Mansuy, F. Guengerich, P. Guengerich, 1996, Biochemistry.

Impact of Chemical Adducts on Translesion Synthesis in Replicative and Bypass DNA Polymerases: From Structure to Function

M. Egli, P. Guengerich, R. Eoff, 2010 .

Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O-Benzylguanine by Sulfolobus solfataricus DNA Polymerase Dpo4 STEADY-STATE AND PRE-STEADY-STATE KINETICS AND X-RAY CRYSTALLOGRAPHY OF CORRECT AND INCORRECT PAIRING*□

M. Egli, P. Guengerich, R. Eoff, 2007 .

Mechanism-Based Inactivation of Human Liver Microsomal Cytochrome P-450 I I IA 4 by Gestodene

P. Guengerich, 2022 .

Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process

P. Guengerich, Kevin D. McCarty, Jesse G. Chapman, 2020, The Journal of biological chemistry.

Characterization of Orphan Human Cytochromes P450

F. Guengerich, P. Guengerich, K. Stark, 2007, Drug metabolism reviews.

“Phase I and Phase II” Drug Metabolism: Terminology that we Should Phase Out?

J. Miners, P. Guengerich, P. David Josephy, 2005, Drug metabolism reviews.

Unusual Cytochrome P450 Enzymes and Reactions*

F. Guengerich, A. Munro, P. Guengerich, 2013, The Journal of Biological Chemistry.

Recombinant Enzymes Overexpressed in Bacteria Show Broad Catalytic Specificity of Human Cytochrome P450 2W1 and Limited Activity of Human Cytochrome P450 2S1

T. Shimada, F. Guengerich, Z. Wu, 2006, Molecular Pharmacology.

Analysis of Coumarin 7-Hydroxylation Activity of Cytochrome P450 2A6 using Random Mutagenesis*

F. Guengerich, Z. Wu, P. Guengerich, 2005, Journal of Biological Chemistry.

Kinetic Analysis of Correct Nucleotide Insertion by a Y-family DNA Polymerase Reveals Conformational Changes Both Prior to and following Phosphodiester Bond Formation as Detected by Tryptophan Fluorescence*

F. Guengerich, P. Guengerich, Qixin Wang, 2008, Journal of Biological Chemistry.

Kinetic Analysis of Translesion Synthesis Opposite Bulky N2- and O6-Alkylguanine DNA Adducts by Human DNA Polymerase REV1*

P. Guengerich, Jeong-Yun Choi, 2008, Journal of Biological Chemistry.

Human cytochrome P450 enzymes bind drugs and other substrates mainly through conformational-selection modes

F. Guengerich, P. Guengerich, Thanh T. N. Phan, 2019, The Journal of Biological Chemistry.

7,8-benzoflavone binding to human cytochrome P450 3A4 reveals complex fluorescence quenching, suggesting binding at multiple protein sites

P. Guengerich, G. Marsch, B. Carlson, 2018, Journal of biomolecular structure & dynamics.

Cooperativity in Oxidation Reactions Catalyzed by Cytochrome P450 1A2

F. Guengerich, D. Stec, P. Guengerich, 2008, Journal of Biological Chemistry.

Multiple Sequential Steps Involved in the Binding of Inhibitors to Cytochrome P450 3A4*

F Peter Guengerich, F. Guengerich, P. Guengerich, 2007, Journal of Biological Chemistry.

Kinetics and Thermodynamics of Ligand Binding by Cytochrome P450 3A4*

F Peter Guengerich, F. Guengerich, P. Guengerich, 2006, Journal of Biological Chemistry.

Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems*

J. Morrow, DelindaA . Johnson, Jeffrey A. Johnson, 2008, Journal of Biological Chemistry.

In Vivo Oxidative Damage in Rats Is Associated with Barbiturate Response but Not Other Cytochrome P450 Inducers

J. Morrow, F. Guengerich, G. Milne, 2007, Molecular Pharmacology.

Evidence for a 1-Electron Oxidation Mechanism in N-Dealkylation of N,N-Dialkylanilines by Cytochrome P450 2B1

F. Guengerich, T. Macdonald, P. Guengerich, 1996, The Journal of Biological Chemistry.

Rate-Limiting Steps in Cytochrome P450 Catalysis

F. Guengerich, P. Guengerich, 2002, Biological chemistry.

Unusual Cytochrome P450 Enzymes and Reactions*

A. Munro, P. Guengerich, 2013, The Journal of Biological Chemistry.

Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis

F. P. Guengerich, P. Guengerich, Kevin D. McCarty, 2021, The Journal of biological chemistry.

Conformational selection dominates binding of steroids to human cytochrome P450 17A1

Michael J Reddish, F. Guengerich, P. Guengerich, 2019, The Journal of Biological Chemistry.

Expansion of Substrate Specificity of Cytochrome P450 2A6 by Random and Site-directed Mutagenesis*

F. Guengerich, Z. Wu, P. Guengerich, 2005, Journal of Biological Chemistry.

Comparison of the inhibitory effects of azole antifungals on cytochrome P450 3A4 genetic variants.

Koujirou Yamamoto, F. Guengerich, Takeshi Akiyoshi, 2021, Drug metabolism and pharmacokinetics.