A. Wood

发表

P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies.

R. Kim, F. Guengerich, C. Wandel, 1999, Cancer research.

Simultaneous determination of codeine and its seven metabolites in plasma and urine by high-performance liquid chromatography with ultraviolet and electrochemical detection.

A. Wood, H. He, S. Shay, 1998, Journal of chromatography. B, Biomedical sciences and applications.

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.

D. Roden, R. Kim, M. Fromm, 1998, The Journal of clinical investigation.

Effects of age and cigarette smoking on propranolol disposition

R. Branch, R. Vestal, G. Wilkinson, 1979, Clinical pharmacology and therapeutics.

A mechanism of D-(+)-sotalol effects on heart rate not related to beta-adrenoceptor antagonism.

D. Roden, C. Funck-Brentano, R. Woosley, 1990, British journal of clinical pharmacology.

Low sodium intake corrects abnormality in β‐receptor–mediated arterial vasodilation in patients with hypertension: Correlation with β‐receptor function in vitro

W. J. Merrell, A. Wood, T. Naslund, 1990 .

Stereoselective disposition and pharmacologic activity of propafenone enantiomers.

D. Roden, M. Eichelbaum, H. Kroemer, 1989, Circulation.

Use of N-ethylmaleimide to directly determine the proportion of beta-adrenergic receptors exhibiting high affinity for agonists on human mononuclear leukocyte membranes.

A. Wood, J. Rigby, A. J. Wood, 1989, Biochemical pharmacology.

Altered β-Adrenoceptor Internalization Does Not Explain Reduced β-Adrenergic Responsiveness in the Elderly

A. Wood, T. Naslund, D. Silberstein, 1989 .

Catecholamine pathway gene variation is associated with norepinephrine and epinephrine concentrations at rest and after exercise

L. Ghimire, C. Stein, A. Wood, 2012, Pharmacogenetics and genomics.

Effect of aging and cigarette smoking on antipyrine and indocyanine green elimination

R. Branch, R. Vestal, G. Wilkinson, 1979, Clinical pharmacology and therapeutics.

Impaired drug metabolism in experimental cirrhosis in the rat.

R. Branch, J. Villeneuve, A. Wood, 1978, Biochemical pharmacology.

Biological determinants of propranolol disposition in man

R. Branch, R. Vestal, G. Wilkinson, 1978, Clinical pharmacology and therapeutics.

A clinical study of sensitivity to sodium nitroprusside during controlled hypotensive anesthesia in young and elderly patients.

S. Hyman, A. Wood, M. Wood, 1986, Anesthesia and analgesia.

Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A

R. Kim, J. Groopman, M. Kinirons, 1999, Clinical pharmacology and therapeutics.

Cyclosporine pharmacokinetics and pharmacodynamics in African American and white subjects

R. Kim, J. Murray, C. Stein, 2001, Clinical pharmacology and therapeutics.

Regulation of human leukocyte beta receptors by endogenous catecholamines: relationship of leukocyte beta receptor density to the cardiac sensitivity to isoproterenol.

D. Robertson, A. Wood, J. Nadeau, 1981, The Journal of clinical investigation.

Alterations in leukocyte beta-receptor affinity with aging. A potential explanation for altered beta-adrenergic sensitivity in the elderly.

R. Feldman, D. Robertson, L. Limbird, 1984, The New England journal of medicine.

Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans.

R. Kim, A. Rettie, C. Stein, 2001, Molecular pharmacology.

Sildenafil does not improve nitric oxide-mediated endothelium-dependent vascular responses in smokers.

Holly L. Bonar, C. Stein, P. Harris, 2003, British journal of clinical pharmacology.

The effect of sildenafil on nitric oxide–mediated vasodilation in healthy men

C. Stein, P. Harris, C. Stein, 2001, Clinical pharmacology and therapeutics.

In-vivo effects of Glu298Asp endothelial nitric oxide synthase polymorphism.

J. Morrow, R. Kim, C. Stein, 2001, Pharmacogenetics.

Decreased intestinal CYP3A in celiac disease: Reversal after successful gluten‐free diet: A potential source of interindividual variability in first‐pass drug metabolism

C. Lang, F. Guengerich, C. Lang, 1996, Clinical pharmacology and therapeutics.

The erythromycin breath test reflects P‐glycoprotein function independently of cytochrome P450 3A activity

G. Wilkinson, A. Wood, D. Kurnik, 2006, Clinical pharmacology and therapeutics.

Identification and Functional Characterization of a New CYP 2 C 9 Variant ( CYP 2 C 9 * 51 ) Expressed among African Americans

R. Kim, A. Rettie, C. Stein, 2001 .

Reduced β‐adrenoceptor sensitivity in the elderly

R. Vestal, A. Wood, D. Shand, 1979 .

Angiotensin converting enzyme inhibition and sympathetic activity in healthy subjects

C. Lang, C. Stein, A. Wood, 1996, Clinical pharmacology and therapeutics.

Effect of thyrotoxicosis on liver blood flow and propranolol disposition after long‐term dosing

P. G. Wells, G. Wilkinson, A. Wood, 1983, Clinical pharmacology and therapeutics.

CYP3A activity in African American and European American men: Population differences and functional effect of the CYP3A4*1B 5′‐promoter region polymorphism

J. Witte, C. Stein, C. Wandel, 2000, Clinical pharmacology and therapeutics.

Effect of sympathoinhibition on exercise performance in patients with heart failure.

C. Lang, J. Wilson, A. Wood, 1997, Circulation.

The Effect of Advancing Age on the Sympathetic Response to Laryngoscopy and Tracheal Intubation

A. Wood, M. Wood, J. Rigby, 1989, Anesthesia and analgesia.

Determinants of anticoagulant control in patients receiving warfarin.

J. Crooks, A. Wood, I. Stevenson, 1977, British journal of clinical pharmacology.

Interaction of Morphine, Fentanyl, Sufentanil, Alfentanil, and Loperamide with the Efflux Drug Transporter P-glycoprotein

R. Kim, C. Wandel, A. Wood, 2002, Anesthesiology.

beta2-Adrenergic receptor genotype and preterm delivery.

Hong-Guang Xie, C. Stein, R. Landau, 2002, American journal of obstetrics and gynecology.

β2-Adrenergic receptor genotype and preterm delivery ☆ ☆☆

Jason H. Moore, Hong-Guang Xie, C. Stein, 2002 .

Increased toxicity and reduced clearance of lidocaine by cimetidine.

G. Wilkinson, A. Wood, J. Feely, 1982, Annals of internal medicine.

Attenuation of isoproterenol-mediated vasodilatation in blacks.

C. Lang, C. Stein, A. Wood, 1995, The New England journal of medicine.

Blunted blood pressure response to central sympathoinhibition in normotensive blacks: increased importance of nonsympathetic factors in blood pressure maintenance in blacks.

C. Lang, I. Blair, C. Stein, 1997, Hypertension.

GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.

C. Stein, A. Wood, M. Muszkat, 2009, Pharmacogenomics.

Disposition kinetics of encainide and metabolites.

D. Roden, R. Woosley, G. Wilkinson, 1986, The American journal of cardiology.

Ethnic differences in drug disposition and response.

A. Wood, A. J. J. Wood, 1998, Therapeutic drug monitoring.

Variation in the &agr;2A adrenoceptor gene and the effect of dexmedetomidine on plasma insulin and glucose

M. Scheinin, L. Ghimire, C. Stein, 2013, Pharmacogenetics and genomics.

Dietary sodium intake modulates systemic but not forearm norepinephrine release

C. Stein, A. Wood, H. He, 1995, Clinical pharmacology and therapeutics.

Suppression of ventricular arrhythmias in man by d-propranolol independent of beta-adrenergic receptor blockade.

K. Murray, D. Roden, C. Reilly, 1990, The Journal of clinical investigation.

Ultra‐short‐acting beta‐blockade: A comparison with conventional beta‐blockade

C. Reilly, A. Wood, M. Wood, 1985, Clinical pharmacology and therapeutics.

Coadministration of glyburide and minoxidil, drugs with opposing effects on potassium channels

N. Brown, C. Stein, C. Stein, 1997, Clinical pharmacology and therapeutics.

Exacerbation of Vasotonic Angina Pectoris by Propranolol

W. Vaughn, D. Robertson, R. Robertson, 1982, Circulation.

Leukocyte :-Receptor Alterations in Hypertensive Subjects

R. Feldman, L. Limbird, A. Wood, 2013 .

Alpha- and beta-adrenergic agonists and antagonists

J. Oates, D. Robertson, R. Woosley, 1983 .

Elevated Plasma Free Drug Concentrations of Propranolol and Diazepam During Cardiac Catheterization

D. Robertson, R. Robertson, G. Wilkinson, 1980, Circulation.

Sympathoinhibitory response to clonidine is blunted in patients with heart failure.

C. Lang, I. Blair, C. Stein, 1997, Hypertension.

Vasodilation in black Americans: Attenuated nitric oxide‐mediated responses

C. Lang, C. Stein, A. Wood, 1997, Clinical pharmacology and therapeutics.

EFFECT OF N-ACETYLCYSTEINE ON HEPATIC COVALENT BINDING OF PARACETAMOL (ACETAMINOPHEN)

J. Villeneuve, R. Harbison, J. Gerber, 1977, The Lancet.

Alterations in leukocyte β-receptor affinity with aging: a potential explanation for altered β-adrenergic sensitivity in the elderly

R. Feldman, D. Robertson, L. Limbird, 1984 .

The sympathetic response to profound hypothermia and circulatory arrest in infants

A. Wood, M. Wood, D. Shand, 1980, Canadian Anaesthetists' Society journal.

Biotransformation of tritiated fentanyl in human liver microsomes. Monitoring metabolism using phenylacetic acid and 2-phenylethanol.

F. Guengerich, A. Wood, M. Wood, 1995, Biochemical pharmacology.

Halothane‐induced Hepatic Necrosis in Triiodothyronine‐pretreated Rats

R. Harbison, A. Wood, M. Wood, 1980, Anesthesiology.

The Effect of Cimetidine on Anesthetic Metabolism and Toxicity

J. Uetrecht, A. Wood, S. Shay, 1986, Anesthesia and analgesia.

Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo.

R. Kim, Hong-Guang Xie, C. Stein, 2004 .

Beta-adrenergic receptor properties of a pulmonary alveolar type II cell preparation from the adult rat

L. G. Jones, A. Wood, M. Gray, 2007, Lung.

Phenytoin metabolic ratio: a putative marker of CYP2C9 activity in vivo.

A. Wood, Y. Caraco, M. Muszkat, 2001, Pharmacogenetics.

after cessation of prostacyclin infusion in sheep Angiotensin II mediates systemic rebound hypertension

C. Stein, B. Christman, A. Wood, 2015 .

Angiotensin II mediates systemic rebound hypertension after cessation of prostacyclin infusion in sheep.

C. Stein, B. Christman, A. Wood, 1998, Journal of applied physiology.

Reduced beta-adrenoceptor sensitivity in the elderly.

R. Vestal, A. Wood, D. Shand, 1979, Clinical pharmacology and therapeutics.

Frequency of functionally important beta-2 adrenoceptor polymorphisms varies markedly among African-American, Caucasian and Chinese individuals.

J. Haines, R. Kim, Hong-hao Zhou, 1999, Pharmacogenetics.

Genetic variants in the &agr;2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses

W. Dupont, Hong-Guang Xie, A. Wood, 2008, Pharmacogenetics and genomics.

Cyclosporine impairs vasodilation without increased sympathetic activity in humans.

T. Pincus, C. Stein, A. Wood, 1995, Hypertension.

Interaction of topical and oral timolol in glaucoma.

A. Wood, D. Shand, D. O'day, 1979, Ophthalmology.

Mibefradil is a potent inhibitor of both CYP3A and P‐glycoprotein (P‐GP)

R. Kim, F. Guengerich, C. Wandel, 1999 .

Altered drug binding due to the use of indwelling heparinized cannulas (heparin lock) for sampling

A. Wood, M. Wood, D. Shand, 1979, Clinical pharmacology and therapeutics.

Effect of acute transdermal estrogen administration on basal, mental stress and cold pressor-induced sympathetic responses in postmenopausal women

C. Stein, A. Wood, G. Sofowora, 2005, Clinical autonomic research : official journal of the Clinical Autonomic Research Society.

Management of hypertension in the elderly.

A. Wood, J. Feely, 1981, Southern medical journal.

Beta2 adrenoceptor THR164ILE polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo

R. Kim, C. Stein, D. Byrne, 2003, Pharmacogenetics.

Effect of i.v. anaesthesia with propofol on drug distribution and metabolism in the dog.

A. Wood, S. Shay, M. Wood, 1991, British Journal of Anaesthesia.

Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol.

K. Badr, C. Stein, T. Inagami, 1995, Hypertension.

Physiological regulation of beta-receptors in man.

R. Feldman, A. Wood, J. Nadeau, 1982, Clinical and experimental hypertension. Part A, Theory and practice.

Metabolism of cytochrome P4503A substrates in vivo administered by the same route: Lack of correlation between alfentanil clearance and erythromycin breath test

M. Kinirons, A. Wood, M. Wood, 1994, Clinical pharmacology and therapeutics.

Editorial: Propranolol Withdrawal Syndrome Why?

A. Wood, D. Shand, 1978, Circulation.

Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension.

C. Stein, A. Wood, H. He, 1995, The Journal of clinical investigation.

Leukocyte beta-receptor alterations in hypertensive subjects.

R. Feldman, D. Robertson, L. Limbird, 1984, The Journal of clinical investigation.

β-Blocker Withdrawal

A. Wood, 1983, Drugs.

Racial Differences in Drug Response

T. Ishizaki, H. Echizen, D. Diven, 1989 .

Changes in Responses to Drugs Acting on Beta Receptors in Aging

A. Wood, A. Wood, 1987 .

Beta receptor sensitivity testing in humans.

A. Wood, 1987, Journal of receptor research.

Pharmacokinetics and Pharmacodynamics of Beta-Blockers

A. Wood, 1982 .

Assessment of β-Adrenoceptor down Regulation in Man

A. Wood, 1980 .

Direct measurement of propranolol bioavailability during accumulation to steady-state.

R. Vestal, G. Wilkinson, A. Wood, 1978, British journal of clinical pharmacology.

Dietary sodium intake modulates vasodilation mediated by nitroprusside but not by methacholine in the human forearm.

C. Stein, A. Wood, M. Wood, 1995, Hypertension.

α2B Adrenergic receptor 301-303 deletion polymorphism and vascular α2 adrenergic receptor response

Hong-Guang Xie, C. Stein, A. Wood, 2005 .

Nitric oxide production decreases after salt loading but is not related to blood pressure changes or nitric oxide-mediated vascular responses

Hong-Guang Xie, C. Stein, A. Wood, 2003, Journal of hypertension.

Variability in beta-adrenergic receptor response in the vasculature: Role of receptor polymorphism.

A. Wood, 2002, The Journal of allergy and clinical immunology.

Regulation of local tissue-type plasminogen activator release by endothelium-dependent and endothelium-independent agonists in human vasculature.

C. Lang, D. Vaughan, N. Brown, 1998, Journal of the American College of Cardiology.

β‐Adrenergic receptor—mediated release of norepinephrine in the human forearm

A. Wood, R. Deegan, Huaibing He, 1993, Clinical pharmacology and therapeutics.

Reduction of liver blood flow and propranolol metabolism by cimetidine.

G. Wilkinson, A. Wood, J. Feely, 1981, The New England journal of medicine.

Norepinephrine release in the human forearm: effects of epinephrine.

C. Stein, A. Wood, H. He, 1997, Hypertension.

Attenuation of Isoproterenol-Mediated Vasodilatation in Blacks: response from authors.

C. Lang, C. Stein, A. Wood, 1995 .

THE EFFECT OF HALOTHANE ON DRUG DISPOSITION: CONTRIBUTIONS OF HEPATIC METABOLISM AND BLOOD FLOW

C. Reilly, A. Wood, M. Wood, 1984 .

Quinidine reduces clearance of (+)‐propranolol more than (−)‐propranolol through marked reduction in 4‐hydroxylation

D. Roden, A. Wood, Hong‐Hao Zhou, 1990, Clinical pharmacology and therapeutics.

Multiple pathways of propranolol's metabolism are inhibited by debrisoquin

A. Wood, L. Anthony, R. Koshakji, 1989, Clinical pharmacology and therapeutics.

Effect of cirrhosis and debrisoquin phenotype on the disposition and effects of pinacidil

A. Wood, M. Hamilton, G. R. Avant, 1986, Clinical pharmacology and therapeutics.

Polymorphic ability to metabolize propranolol alters 4‐hydroxypropranolol levels but not beta blockade

G. Wilkinson, A. Wood, R. Koshakji, 1984, Clinical pharmacology and therapeutics.

Influence of genetic polymorphism on the metabolism and disposition of encainide in man.

D. Roden, T. Wang, R. Woosley, 1984, The Journal of pharmacology and experimental therapeutics.

No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia.

Hong-Guang Xie, C. Stein, R. Landau, 2004, American journal of hypertension.

TIMOLOL MALEATE—A PROMISING NEW BETA ADRENERGIC BLOCKER FOR GLAUCOMA

A. Wood, D. Shand, D. O'day, 1979 .

A common beta1-adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to beta-blockade.

R. Kim, U. B. Nair, C. Stein, 2003, Clinical pharmacology and therapeutics.

Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat.

R. Branch, J. Villeneuve, A. Wood, 1979, Gastroenterology.

α1A‐adrenergic Receptor Polymorphism and Vascular Response

R. Kim, Hong-Guang Xie, C. Stein, 2004 .

Perioperative beta blockade with propranolol: reduction in myocardial oxygen demands and incidence of atrial and ventricular arrhythmias.

J. Hammon, H. Bender, A. Wood, 1984, The Annals of thoracic surgery.

Nitroglycerin Use During Placebo and Propranolol Trial Placebo Low High Placebo

W. Vaughn, D. Robertson, R. Robertson, 2022 .

Basal and stimulated sympathetic responses after epinephrine: no evidence of augmented responses.

C. Stein, A. Wood, H. He, 1998, Hypertension.

Alpha2-Adrenergic Receptor–Induced Vascular Constriction in Blacks and Whites

C. Stein, A. Wood, M. Muszkat, 2004, HYPERTENSION.

Alpha 2-Adrenergic Receptor – Induced Vascular Constriction in Blacks and Whites

C. Stein, A. Wood, M. Muszkat, 2003 .

Calcium Antagonists: Pharmacologic Differences and Similarities

A. Wood, 1989, Circulation.

Low sodium intake corrects abnormality in beta-receptor-mediated arterial vasodilation in patients with hypertension: correlation with beta-receptor function in vitro.

W. J. Merrell, A. Wood, T. Naslund, 1990, Clinical pharmacology and therapeutics.

Changes in plasma drug binding and α1‐acid glycoprotein in mother and newborn infant

A. Wood, M. Wood, 1981 .

Effects of variation in the human α2A‐ and α2C‐adrenoceptor genes on cognitive tasks and pain perception

W. Dupont, M. Scheinin, C. Stein, 2010, European journal of pain.

The α2C-adrenoceptor deletion322–325 variant and cold-induced vasoconstriction

C. Stein, P. Harris, A. Wood, 2009, Clinical Autonomic Research.

Drug Interactions in Hypertension

A. Wood, A. J. Wood, 1988, Hypertension.

Intact hepatocyte theory of impaired drug metabolism in experimental cirrhosis in the rat.

R. Branch, J. Villeneuve, A. Wood, 1979, Gastroenterology.

Influence of Age and Smoking on Drug Kinetics in Man Studies Using Model Compounds

R. Vestal, A. Wood, 1980, Clinical pharmacokinetics.

Effects of cimetidine on the elimination and actions of ethanol.

A. Wood, J. Feely, 1982, JAMA.

Exacerbation ofVasotonic Angina Pectoris byPropranolol

A. Wood, B. Ch, 1982 .

Implementation of multiple outpatient formularies: Undesirable effects

T. Pincus, C. Stein, A. Wood, 1997, Clinical pharmacology and therapeutics.

α‐Adrenergic blockade makes minimal contribution to ketanserin's hypotensive effect

W. J. Merrell, A. Wood, T. Naslund, 1988, Clinical pharmacology and therapeutics.

Alpha1A-adrenergic receptor polymorphism: association with ethnicity but not essential hypertension.

R. Kim, N. Brown, C. Stein, 1999, Pharmacogenetics.

Influence of debrisoquin phenotype on the inducibility of propranolol metabolism

J. Biollaz, G. Wilkinson, A. Wood, 1989, Clinical pharmacology and therapeutics.

Improved high-performance liquid chromatographic method for the simultaneous determination of propranolol and 4-hydroxypropranolol in plasma with fluorescence detection.

A. Wood, R. Koshakji, 1987, Journal of chromatography.

effects bi: pinacidil disposition and

A. Wood, M. Hamilton, G. R. Avant, 1986 .

The Influence of Cirrhosis on Steady-State Blood Concentrations of Unbound Propranolol after Oral Administration

R. Branch, G. Wilkinson, A. Wood, 1978, Clinical pharmacokinetics.

Simultaneous determination of propranolol enantiomers in plasma by high-performance liquid chromatography with fluorescence detection.

C. Prakash, I. Blair, A. Wood, 1989, Journal of pharmaceutical sciences.

Propranolol Binding in Plasma during Cardiopulmonary Bypass

A. Wood, M. Wood, D. Shand, 1979, Anesthesiology.

Effect on apparent liver blood flow of histamine‐receptor blockers and inhibition of prostaglandin synthesis

A. Wood, J. Feely, 1983, Clinical pharmacology and therapeutics.

Pharmacokinetic Drug Interactions with Propranolol

A. Wood, J. Feely, 1983, Clinical Pharmacokinetics.

Propranolol disposition in renal failure.

R. Vestal, G. Wilkinson, A. Wood, 1980, British journal of clinical pharmacology.

Effect of heparin administration on plasma binding of benzodiazepines.

S. Schenker, P. Desmond, G. Wilkinson, 1980, British journal of clinical pharmacology.

Contrasting Effects on Halothane Hepatotoxicity in the Phenobarbital-Hypoxia and Triiodothyronine Model: Mechanistic Implications

J. Uetrecht, A. Wood, M. Wood, 1983, Anesthesiology.

Molecular basis of ethnic differences in drug disposition and response.

R. Kim, C. Stein, C. Stein, 2001, Annual review of pharmacology and toxicology.

Alfentanil Disposition In Vivo Is Mediated By Cyp3a4 In Humans

M. Kinirons, A. Wood, M. Wood, 1994 .

Genetic Variations in the &agr;2A-Adrenoreceptor Are Associated With Blood Pressure Response to the Agonist Dexmedetomidine

M. Scheinin, C. Stein, A. Wood, 2011, Circulation. Cardiovascular genetics.

Desensitization of vascular response in vivo: contribution of genetic variation in the α2B-adrenergic receptor subtype

Scott M. Williams, C. Stein, P. Harris, 2010, Journal of hypertension.

Variations in the α2A‐adrenergic receptor gene and their functional effects

Hong-Guang Xie, Lan Jiang, P. Harris, 2006 .

Variation in the &agr;2B-adrenergic receptor gene (ADRA2B) and its relationship to vascular response in vivo

Scott M. Williams, Hong-Guang Xie, Lan Jiang, 2005, Pharmacogenetics and genomics.

CYP2A6 genetic variation and dexmedetomidine disposition

R. Tyndale, M. Scheinin, P. Pandharipande, 2012, European Journal of Clinical Pharmacology.

Pharmacologic differences between beta blockers.

A. Wood, 1984, American heart journal.

Enprostil, in contrast to cimetidine, does not inhibit propranolol metabolism

J. Biollaz, C. Reilly, A. Wood, 1986, Clinical pharmacology and therapeutics.

Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes.

G R Wilkinson, R. Kim, C. Wandel, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Routine Therapeutic Monitoring of Lamotrigine in Epileptic Patients Using a Simple and Rapid High Performance Liquid Chromatographic Technique

R. Braithwaite, A. Wood, S. George, 1995, Annals of clinical biochemistry.

The tryptophan hydroxylase inhibitor LX1031 shows clinical benefit in patients with nonconstipating irritable bowel syndrome.

D. Drossman, G. Cline, A. Sands, 2011, Gastroenterology.

Inhibition of stimulated interleukin-2 production in whole blood: a practical measure of cyclosporine effect.

J. Murray, C. Stein, C. Stein, 1999, Clinical chemistry.

Lack of correlation between arterial and venous beta-adrenergic receptor sensitivity.

C. Stein, A. Wood, R. Deegan, 1997, Hypertension.

Differential in Vivo Sensitivity to Inhibition of P-glycoprotein Located in Lymphocytes, Testes, and the Blood-Brain Barrier

R. Kim, H. Glaeser, E. Choo, 2006, Journal of Pharmacology and Experimental Therapeutics.

Interrelationship Between Substrates and Inhibitors of Human CYP3A and P-Glycoprotein

Mark M. Roden, D. Roden, M. Fromm, 1999, Pharmaceutical Research.

Genetic variability in CYP3A5 and its possible consequences.

R. Kim, Hong-Guang Xie, C. Stein, 2004, Pharmacogenomics.

Optimization of high-performance liquid chromatographic assay for catecholamines. Determination of optimal mobile phase composition and elimination of species-dependent differences in extraction recovery of 3,4-dihydroxybenzylamine.

A. Wood, H. He, M. Wood, 1992, Journal of chromatography.

Ethnic and Genetic Determinants of Cardiovascular Response to the Selective &agr;2-Adrenoceptor Agonist Dexmedetomidine

W. Dupont, M. Scheinin, C. Stein, 2008, Hypertension.

Effect of the α2C-adrenoreceptor deletion322–325 variant on sympathetic activity and cardiovascular measures in healthy subjects

Hong-Guang Xie, A. Diedrich, Leena Choi, 2007, Journal of hypertension.

Increased Vascular Adrenergic Vasoconstriction and Decreased Vasodilation in Blacks: Additive Mechanisms Leading to Enhanced Vascular Reactivity

C. Lang, C. Stein, A. Wood, 2000, Hypertension.

Plasma Binding of Pancuronium: Effects of Age, Sex, and Disease

A. Wood, M. Wood, W. Stone, 1983, Anesthesia and analgesia.

Drugs and Anesthesia: Pharmacology for Anesthesiologists

A. Wood, M. Wood, 1989 .

The Effect of Halothane on Drug Disposition: Contribution of Changes in Intrinsic Drug Metabolizing Capacity and Hepatic Blood Flow

C. Reilly, A. Wood, M. Wood, 1985, Anesthesiology.

Differences in stereoselective disposition of propranolol do not explain sensitivity differences between white and Chinese subjects: Correlation between the clearance of (−)‐ and (+)‐propranolol

A. Wood, Hong-hao Zhou, 1990, Clinical pharmacology and therapeutics.

Racial differences in drug response. Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites.

G R Wilkinson, H. Zhou, G. Wilkinson, 1989, The New England journal of medicine.

Plasma Binding of Pancuronium: Effects of Age, Sex, and Disease

A. Wood, M. Wood, W. Stone, 1980, Anesthesia and analgesia.

A new method for constant plasma drug concentrations: application to lidocaine.

D. Roden, G. Wilkinson, A. Wood, 1984, Annals of internal medicine.

Effects of anesthesia on norepinephrine kinetics. Comparison of propofol and halothane anesthesia in dogs.

A. Wood, H. He, M. Wood, 1991, Anesthesiology.

β‐Receptor antagonism does not fully explain esmolol‐induced hypotension

A. Wood, R. Deegan, 1994, Clinical pharmacology and therapeutics.

COMPARATIVE POTENCIES OF ESMOLOL, A SHORT-ACTING BETA-BLOCKER, AND PROPRANOLOL IN MAN

C. Reilly, A. Wood, M. Wood, 1984 .

Impact of ethnic origin and quinidine coadministration on codeine's disposition and pharmacodynamic effects.

J. Sheller, A. Wood, Y. Caraco, 1999, The Journal of pharmacology and experimental therapeutics.

Pharmacogenetic determination of the effects of codeine and prediction of drug interactions.

J. Sheller, A. Wood, Y. Caraco, 1996, The Journal of pharmacology and experimental therapeutics.

Stereoselective disposition of carvedilol is determined by CYP2D6

A. Wood, Hong-hao Zhou, 1995, Clinical pharmacology and therapeutics.

Lack of effect of ageing on the stereochemical disposition of propranolol.

H. Zhou, A. Wood, E. Whelan, 1992, British journal of clinical pharmacology.

Racial differences in drug response.

G. Wilkinson, A. Wood, Honghao Zhou, 1989, The New England journal of medicine.

ACUTE EFFECT OF HALOTHANE (H) ON DRUG DISTRIBUTION

A. Wood, S. Shay, M. Wood, 1989 .

Determination of catecholamines in sheep plasma by high-performance liquid chromatography with electrochemical detection: comparison of deoxyepinephrine and 3,4-dihydroxybenzylamine as internal standard.

Cynthia M. Stein, C. Stein, B. Christman, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Changes in plasma drug binding and alpha 1-acid glycoprotein in mother and newborn infant.

A. Wood, M. Wood, 1981, Clinical pharmacology and therapeutics.

CIMETIDINE PROTECTS AGAINST HALOTHANE-INDUCED HEPATOTOXICITY

A. Wood, M. Wood, J. Phythyon, 1982 .

Comparison of the effects of isoflurane or fentanyl-nitrous oxide anaesthesia on propranolol disposition in dogs.

C. Reilly, A. Wood, M. Wood, 1988, British journal of anaesthesia.

The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization.

R. Kim, C. Stein, D. Byrne, 2001, The New England journal of medicine.

THE EFFECT OF FENTANYL-ANESTHESIA ON DRUG DISPOSITION

C. Reilly, A. Wood, M. Wood, 1985 .

Ethnic differences in response to morphine.

J. Sheller, H. Zhou, A. Wood, 1995, Clinical pharmacology and therapeutics.

A Multi-Investigator/Institutional DNA Bank for AIDS-Related Human Genetic Studies: AACTG Protocol A5128

David W. Haas, Douglas D. Richman, Margaret A. Matula, 2003, HIV clinical trials.

Increased drug delivery to the brain by P‐glycoprotein inhibition

C. Wandel, A. Wood, H. He, 2000, Clinical pharmacology and therapeutics.

Genetic polymorphism of (S)-mephenytoin 4'-hydroxylation in populations of African descent.

R. Kim, C. Stein, G. Wilkinson, 1999, British journal of clinical pharmacology.

The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone.

D. Roden, H. Kroemer, C. Funck-Brentano, 1990, The New England journal of medicine.

Colchicine biotransformation by human liver microsomes. Identification of CYP3A4 as the major isoform responsible for colchicine demethylation.

P. Souček, F. Guengerich, A. Wood, 1997, Biochemical pharmacology.

Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein

U. B. Nair, G. Wilkinson, A. Wood, 2008, Anesthesiology.

Levodopa and positive direct antiglobulin tests.

A. Wood, J. Davidson, D. Moir, 1975, British journal of clinical pharmacology.

Pharmacogenetic determinants of codeine induction by rifampin: the impact on codeine's respiratory, psychomotor and miotic effects.

J. Sheller, A. Wood, Y. Caraco, 1997, The Journal of pharmacology and experimental therapeutics.

Induction of propranolol metabolism by rifampicin.

G. Wilkinson, A. Wood, R. Herman, 1983, British journal of clinical pharmacology.

Allelic, genotypic and phenotypic distributions of S-mephenytoin 4'-hydroxylase (CYP2C19) in healthy Caucasian populations of European descent throughout the world.

R. Kim, D. Flockhart, C. Stein, 1999, Pharmacogenetics.

Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine

T. Pincus, C. Stein, M. Kinirons, 1996, Clinical pharmacology and therapeutics.

Ethnic and genetic determinants of omeprazole disposition and effect

A. Wood, Y. Caraco, P. Lagerstrom, 1996, Clinical pharmacology and therapeutics.

Triazolam pharmacokinetics and pharmacodynamics in Caucasians and Southern Asians: ethnicity and CYP3A activity.

D. W. Robin, C. Lang, M. Kinirons, 1996, British journal of clinical pharmacology.

The effect of halothane on morphine disposition: relative contributions of the liver and kidney to morphine glucuronidation in the dog.

W. J. Merrell, E. Jackson, A. Wood, 1990, Anesthesiology.

A common β1‐adrenergic receptor polymorphism (Arg389Gly) affects blood pressure response to β‐blockade

U. B. Nair, P. Harris, C. Stein, 2003 .

Arg389Gly beta 1-adrenoceptor polymorphism varies in frequency among different ethnic groups but does not alter response in vivo.

R. Kim, C. Stein, P. Harris, 2001, Pharmacogenetics.

Dynamic regulation of leukocyte beta adrenergic receptor-agonist interactions by physiological changes in circulating catecholamines.

R. Feldman, D. Robertson, L. Limbird, 1983, The Journal of clinical investigation.

Pharmacokinetic and Pharmacological Aspects of Polymorphic Drug Oxidation in Man

D. Roden, R. Branch, R. Woosley, 1984 .

Pharmacogenetic explanation for excessive beta-blockade following timolol eye drops. Potential for oral-ophthalmic drug interaction.

T. Edeki, A. Wood, H. He, 1995, JAMA.

Contribution of differences in plasma binding of propranolol to ethnic differences in sensitivity. Comparison between Chinese and Caucasians.

H. Zhou, A. Wood, S. Shay, 1993, Chinese medical journal.

Increased suppression of exercise‐induced increase in renin by propranolol in Chinese subjects

A. Wood, Hong-hao Zhou, 1991, Clinical pharmacology and therapeutics.

Beta-1-adrenoceptor genetic variants and ethnicity independently affect response to beta-blockade

Scott M. Williams, Hong-Guang Xie, U. B. Nair, 2008, Pharmacogenetics and genomics.

Interethnic difference in omeprazole's inhibition of diazepam metabolism

A. Wood, Y. Caraco, T. Tateishi, 1995, Clinical pharmacology and therapeutics.

Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin.

H. Zhou, G. Wilkinson, A. Wood, 1990, British journal of clinical pharmacology.

R. Shiavi, S. Hasan, D. W. Robin, 1991, Clinical pharmacology and therapeutics.

Human β2‐adrenergic receptor polymorphisms: No association with essential hypertension in black or white Americans

J. Haines, N. Brown, C. Stein, 2000, Clinical pharmacology and therapeutics.

Drug interaction studies and encainide use in renal and hepatic impairment.

A. Wood, B. Quart, D. Gallo, 1986, The American journal of cardiology.

G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy.

R. Kim, Hong-Guang Xie, C. Stein, 2003, Pharmacogenetics.

Hypertension in black people: study of specific genotypes and phenotypes will provide a greater understanding of interindividual and interethnic variability in blood pressure regulation than studies based on race.

C. Lang, C. Stein, C. Lang, 2001, Pharmacogenetics.

Encainide disposition in patients with renal failure

D. Roden, R. Bergstrand, R. Woosley, 1986, Clinical pharmacology and therapeutics.

Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro.

R. Kim, F. Guengerich, C. Wandel, 2000, Drug metabolism and disposition: the biological fate of chemicals.

A POTENT INHIBITOR OF BOTH P-GLYCOPROTEIN AND CYP 3 A IN VITRO

R. Kim, F. Guengerich, C. Wandel, 2000 .

Evidence of increased CPY3A4 activity in African Americans

M. Kinirons, A. Wood, C. C. Lang, 1996 .

Drug interactions with Ethmozine (moricizine HCl).

H. Kennedy, A. Wood, R. Macfarland, 1987, The American journal of cardiology.

Elimination kinetics of labetalol in severe renal failure.

D. Ferry, A. Wood, R. Bailey, 1982, British journal of clinical pharmacology.

Disproportionate Decrease in &agr;- Compared With &bgr;-Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation

C. Stein, R. Landau, R. Smiley, 2002, Circulation.

Disproportionate Decrease in-Compared With -Adrenergic Sensitivity in the Dorsal Hand Vein in Pregnancy Favors Vasodilation

C. Stein, R. Landau, R. Smiley, 2002 .

Medicines Evaluation and Monitoring Group: Central Nervous System Effects of Pentazocine

A. Wood, E. Henney, J. Davidson, 1974, British medical journal.

The Effects of Tadalafil on Cold‐induced Vasoconstriction in Patients with Raynaud's Phenomenon

C. Stein, P. Harris, C. Stein, 2007, Clinical pharmacology and therapeutics.

Biological determinants of propranolol disposition in normal subjects and patients with cirrhosis [proceedings].

R. Branch, G. Wilkinson, A. Wood, 1977, British journal of clinical pharmacology.

Cimetidine alters plasma catecholamine levels and cortisol and aldosterone excretion.

A. Wood, J. Feely, D. Island, 1982, New England Journal of Medicine.

Electrophysiologic actions of high plasma concentrations of propranolol in human subjects.

A. K. Dawson, D. Roden, J. Oates, 1983, Journal of the American College of Cardiology.

Independent regulation of α1 and α2 adrenergic receptor-mediated vasoconstriction in vivo

C. Stein, A. Wood, M. Muszkat, 2011, Journal of hypertension.

Variability of fentanyl pharmacokinetics in man. Computer predicted plasma concentrations for three intravenous dosage regimens.

C. Reilly, A. Wood, M. Wood, 1985, Anaesthesia.

Erythromycin breath test (multiple letters)

P. Watkins, R. Kim, M. Kinirons, 2000 .

Microsomal codeine N-demethylation: cosegregation with cytochrome P4503A4 activity.

F. Guengerich, A. Wood, Y. Caraco, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Effect of inhibitors of prostaglandin synthesis on hepatic drug clearance.

A. Wood, J. Feely, 1983, British journal of clinical pharmacology.

Determination of low plasma timolol concentrations following topical application of timolol eye drops in humans by high-performance liquid chromatography with electrochemical detection.

T. Edeki, A. Wood, H. He, 1994, Journal of chromatography. B, Biomedical applications.

Long‐term exposure to β2‐receptor agonist specifically desensitizes β‐receptor—mediated venodilation

A. Wood, R. Deegan, M. Stein, 1993 .

Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response.

C. Stein, A. Wood, M. Muszkat, 2005, Pharmacogenetics and genomics.

Effects of ketoconazole on the erythromycin breath test and the dapsone recovery ratio.

M. Kinirons, G. Wilkinson, A. Wood, 1999, British journal of clinical pharmacology.

Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men

J. Groopman, M. Kinirons, G. Wilkinson, 1993, Clinical pharmacology and therapeutics.

Sensitive assay for triazolam in plasma following low oral doses.

D. W. Robin, C. Prakash, I. Blair, 1992, Journal of chromatography.

A modified, sensitive liquid chromatographic method for measurement of propranolol with fluorescence detection.

A. Wood, R. Koshakji, 1986, Journal of pharmaceutical sciences.

Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test.

A. Wood, A J Wood, T Tateishi, 1995, British journal of clinical pharmacology.

Sympathetic activation in the elderly: is it due to impaired alpha adrenergic feedback sympathoinhibition?

C. Lang, I. Blair, C. Stein, 1997 .

Alpha 1A-adrenergic receptor polymorphism and vascular response.

R. Kim, Hong-Guang Xie, C. Stein, 2004, Clinical pharmacology and therapeutics.

Abnormalities of the QT interval in primary disorders of autonomic failure.

D. Roden, C. Lang, A. Choy, 1998, American heart journal.

Identification of the pharmacogenetic determinants of alfentanil metabolism: cytochrome P-450 3A4. An explanation of the variable elimination clearance.

F. Guengerich, A. Wood, M. Wood, 1992, Anesthesiology.

Effects of feeding on the systemic clearance of indocyanine green and propranolol blood concentrations and plasma binding.

A. Wood, J. Feely, J. Nadeau, 1983, British journal of clinical pharmacology.

Triazolam in cirrhosis: Pharmacokinetics and pharmacodynamics

S. Hasan, D. W. Robin, A. Wood, 1993, Clinical pharmacology and therapeutics.

Electrophysiological effects of high-dose propranolol in dogs: evidence in vivo for effects not mediated by the beta adrenoceptor.

A. K. Dawson, H. Duff, R. Woosley, 1984, The Journal of pharmacology and experimental therapeutics.

EFFECTS OF PROPOFOL ON DRUG DISPOSITION: MARKED EFFECTS ON DRUG DISTRIBUTION, LESS EFFECT ON DRUG METABOLISM

A. Wood, S. Shay, M. Wood, 1988 .

Acute Effects of Halothane Anesthesia on Arterial and Venous Concentrations of Propranolol in the Dog

G. Wilkinson, A. Wood, M. Wood, 1987, Anesthesiology.

Quantitation of loperamide and N-demethyl-loperamide in human plasma using electrospray ionization with selected reaction ion monitoring liquid chromatography-mass spectrometry.

D. Hachey, A. Wood, H. He, 2000, Journal of chromatography. B, Biomedical sciences and applications.

CYP2A6 genetic variation and dexmedetomidine disposition

R. Tyndale, M. Scheinin, P. Pandharipande, 2012, European Journal of Clinical Pharmacology.

Ethnic and genetic determinants of omeprazole disposition and effect

A. Wood, Y. Caraco, P. Lagerstrom, 1996 .

Cerebrospinal fluid concentration of metoprolol in a hypertensive patient.

A. Wood, 1977, British journal of clinical pharmacology.

Pharmacokinetic Drug Interactions with Propranolol

A. Wood, J. Feely, 1983, Clinical pharmacokinetics.

Reduction of liver blood flow and propranolol metabolism by cimetidine.

G. Wilkinson, A. Wood, J. Feely, 1981, The New England journal of medicine.

Halothane inhibition of propranolol metabolism is stereoselective.

A. Wood, S. Shay, M. Wood, 1989, Anesthesiology.

Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein

U. B. Nair, G. Wilkinson, A. Wood, 2008, Anesthesiology.