M. Bridgland-Taylor

发表

An introduction to QT interval prolongation and non‐clinical approaches to assessing and reducing risk

J. Valentin, A. Easter, C. Pollard, 2010, British journal of pharmacology.

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm

T. Colatsky, B. Fermini, G. Gintant, 2016, Journal of biomolecular screening.

A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.

Matthew H Bridgland-Taylor, Alison J Foster, Alison J. Foster, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

Optimisation and validation of a medium-throughput electrophysiology-based hERG assay using IonWorks HT.

B. Small, E. Sullivan, J. Valentin, 2006, Journal of pharmacological and toxicological methods.

Validation of a voltage-sensitive dye (di-4-ANEPPS)-based method for assessing drug-induced delayed repolarisation in beagle dog left ventricular midmyocardial myocytes.

B. Small, J. Valentin, C. Pollard, 2009, Journal of pharmacological and toxicological methods.

Evaluation of drug-induced QT interval prolongation in animal and human studies: a literature review of concordance

Sherri Matis-Mitchell, S. Pettit, M. Skinner, 2015, British journal of pharmacology.

Prediction and Modeling of Effects on the QTc Interval for Clinical Safety Margin Assessment, Based on Single-Ascending-Dose Study Data with AZD3839

Michael D B Swedberg, C. Pollard, M. Bridgland-Taylor, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Pharmacological and electrophysiological characterisation of hERG activator AZSMO-23 1 Running title : Characterisation of hERG activator AZSMO-23

N. Abi-Gerges, M. Bridgland-Taylor, S. Swallow, 2015 .

A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm

James Kramer, David G Strauss, Liudmila Polonchuk, 2020, Toxicology and applied pharmacology.

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

Gary R. Mirams, David J. Gavaghan, Najah Abi-Gerges, 2014, Journal of pharmacological and toxicological methods.

Mutations of the nACh Receptor M4 Helix Reveal Different Phenotypes in Different Expression Systems: Could Lipids be Responsible?

S. Lummis, M. Bridgland-Taylor, Susanne M. Mesoy, 2022, Frontiers in Physiology.

Pharmacological and electrophysiological characterization of AZSMO‐23, an activator of the hERG K+ channel

N. Abi-Gerges, M. Bridgland-Taylor, S. Swallow, 2015, British journal of pharmacology.