K. Chaudhary

发表

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm

T. Colatsky, B. Fermini, G. Gintant, 2016, Journal of biomolecular screening.

Human Stem Cell‐Derived Cardiomyocyte In Vitro Models for Cardiotoxicity Screening

K. Chaudhary, Tracy M Walker, K. Harris, 2016 .

Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

Time for a Fully Integrated Nonclinical–Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective

G. Gintant, A. Pointon, A. Bahinski, 2020, Clinical pharmacology and therapeutics.

Evaluation of the rubidium efflux assay for preclinical identification of HERG blockade.

Robert H Gallavan, B. Fermini, A. Bahinski, 2006, Assay and drug development technologies.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

G. Gintant, Jennifer B Pierson, B. Berridge, 2019, Front. Pharmacol..

Novel KV7 ion channel openers for the treatment of epilepsy and implications for detrusor tissue contraction.

Dwight M. Morrow, G. Higgins, Y. Matsuoka, 2018, Bioorganic & medicinal chemistry letters.

Embryonic stem cells in predictive cardiotoxicity: laser capture microscopy enables assay development.

J. Mcneish, A. Milici, A. Bahinski, 2006, Toxicological sciences : an official journal of the Society of Toxicology.

Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug Discovery

Danielle R. Bogdanowicz, R. Willette, M. Graziano, 2019, Toxicological sciences : an official journal of the Society of Toxicology.

Applying the CiPA approach to evaluate cardiac proarrhythmia risk of some antimalarials used off‐label in the first wave of COVID‐19

Matthew M. Abernathy, Warren D. Anderson, Eric I. Rossman, 2021, Clinical and translational science.

Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.

J. Bertin, M. Convery, D. Lipshutz, 2018, ACS medicinal chemistry letters.

Cardiotoxicity screening with simultaneous optogenetic pacing, voltage imaging and calcium imaging.

Cuong Nguyen, Adam E Cohen, Graham T Dempsey, 2016, Journal of pharmacological and toxicological methods.

Altered myocardial Ca2+ cycling after left ventricular assist device support in the failing human heart.

Eric I. Rossman, S. Houser, J. Gaughan, 2004, Journal of the American College of Cardiology.

Impaired contractile reserve in severe mitral valve regurgitation with a preserved ejection fraction

Eric I. Rossman, S. Houser, J. Gaughan, 2007, European journal of heart failure.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms

Tanja Zabka, John Koerner, Gary Gintant, 2019, Front. Pharmacol..

Utility of Normalized TdP Score System in Drug Proarrhythmic Potential Assessment: A Blinded in vitro Study of CiPA Drugs

Jiang Liu, G. Yan, Tengxian Liu, 2020, Clinical pharmacology and therapeutics.

Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells

B. Fermini, G. Gintant, Jennifer B Pierson, 2020, Scientific Reports.

Cardiac sodium channel inhibition by lamotrigine: In vitro characterization and clinical implications

J. A. Cooper, O. Della Pasqua, A. Bahinski, 2022, Clinical and translational science.

Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium.

Eric I. Rossman, S. Houser, J. Gaughan, 2004, Journal of molecular and cellular cardiology.

Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel.

Carol A. Capriotti, J. Bertin, M. Convery, 2018, ACS medicinal chemistry letters.