Liang Guo

发表

International Multisite Study of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Proarrhythmic Potential Assessment

Daniel C Millard, G. Gintant, Jennifer B Pierson, 2018, Cell reports.

Cross-Site Reliability of Human Induced Pluripotent stem cell-derived Cardiomyocyte Based Safety Assays Using Microelectrode Arrays: Results from a Blinded CiPA Pilot Study

Qianyu Dang, Gary Gintant, Hong Shi, 2018, Toxicological sciences : an official journal of the Society of Toxicology.

Altered cytosolic Ca2+ dynamics in cultured Guinea pig cardiomyocytes as an in vitro model to identify potential cardiotoxicants.

Liang Guo, Jian-Yong Qian, 2010, Toxicology in vitro : an international journal published in association with BIBRA.

Automated electrophysiology in the preclinical evaluation of drugs for potential QT prolongation.

Liang Guo, Heather Guthrie, Liang Guo, 2005, Journal of pharmacological and toxicological methods.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

G. Gintant, Jennifer B Pierson, B. Berridge, 2019, Front. Pharmacol..

The effects of jaspamide on human cardiomyocyte function and cardiac ion channel activity.

K. Kolaja, E. Chiao, Myrtle A. Davis, 2013, Toxicology in vitro : an international journal published in association with BIBRA.

Estimating the risk of drug-induced proarrhythmia using human induced pluripotent stem cell-derived cardiomyocytes.

Liang Guo, K. Kolaja, S. Kameoka, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

Validation of a guinea pig Langendorff heart model for assessing potential cardiovascular liability of drug candidates.

Liang Guo, Zedong Dong, H. Guthrie, 2009, Journal of pharmacological and toxicological methods.

Use of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes (hiPSC‐CMs) to Monitor Compound Effects on Cardiac Myocyte Signaling Pathways

Myrtle A. Davis, Liang Guo, S. Eldridge, 2015, Current protocols in chemical biology.

Examining the protective role of ErbB2 modulation in human-induced pluripotent stem cell-derived cardiomyocytes.

John R. Hamre, Myrtle A. Davis, Liang Guo, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

A Comparative Review of Chemotherapy-Induced Peripheral Neuropathy in In Vivo and In Vitro Models

John R. Hamre, Liang Guo, S. Eldridge, 2020, Toxicologic pathology.

Editor’s Highlight: Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics

John R. Hamre, Myrtle A. Davis, Liang Guo, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Long-term low-dose ionizing radiation induced chromosome-aberration-specific metabolic phenotype changes in radiation workers.

Q. Zhang, Bin Wu, Liang Guo, 2022, Journal of pharmaceutical and biomedical analysis.

Peroxisome proliferator-activated receptor gamma as a drug target in the pathogenesis of insulin resistance.

Liang Guo, R. Tabrizchi, 2006, Pharmacology & therapeutics.

Haemodynamic effects of vasoactive agents following chronic state of high cardiac output in anaesthetized rats.

Liang Guo, R. Tabrizchi, 2008, European journal of pharmacology.

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

James A Thomson, Liang Guo, K. Kolaja, 2011, American journal of physiology. Heart and circulatory physiology.

Multi-parametric assessment of cardiomyocyte excitation-contraction coupling using impedance and field potential recording: A tool for cardiac safety assessment.

Myrtle Davis, Haoyu Zeng, Liang Guo, 2016, Journal of pharmacological and toxicological methods.

Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model.

Liang Guo, K. Kolaja, E. Chiao, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line

Clay W Scott, Matthew F. Peters, Liang Guo, 2014, Cardiovascular Toxicology.

Human Stem Cell-Derived Cardiomyocytes in Cellular Impedance Assays: Bringing Cardiotoxicity Screening to the Front Line

Clay W Scott, K. Kolaja, M. F. Peters, 2015, Cardiovascular Toxicology.

Human CD34(+) progenitor hematopoiesis in liquid culture for in vitro assessment of drug-induced myelotoxicity.

John R. Hamre, R. Parchment, Myrtle A. Davis, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Adverse Drug-Induced Inotropic Effects in Early Drug Development. Part 1: General Considerations for Development of Novel Testing Platforms

Tanja Zabka, John Koerner, Gary Gintant, 2019, Front. Pharmacol..

Role of Mcl‐1 in regulation of cell death in human induced pluripotent stem cell‐derived cardiomyocytes in vitro

Myrtle A. Davis, Liang Guo, S. Eldridge, 2018, Toxicology and applied pharmacology.

The Electrophysiological Effects of Cardiac Glycosides in Human iPSC-derived Cardiomyocytes and in Guinea Pig Isolated Hearts

Thomas Weiser, Liang Guo, K. Kolaja, 2011, Cellular Physiology and Biochemistry.

Title : Cross-Site Reliability of Human Induced Pluripotent Stem-Cell Derived Cardiomyocyte Based Safety Assays using Microelectrode Arrays : Results from a Blinded CiPA Pilot Study Running Title : CiPA hSC-CM MEA Pilot Study

G. Gintant, Jennifer B Pierson, C. Strock, 2018 .

Use of human stem cell derived cardiomyocytes to examine sunitinib mediated cardiotoxicity and electrophysiological alterations.

K. Kolaja, J. Taunton, S. Kameoka, 2011, Toxicology and applied pharmacology.

Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)

H. R. Lu, M. Kreir, D. Gallacher, 2023, Frontiers in pharmacology.

Assessing drug-induced long QT and proarrhythmic risk using human stem cell-derived cardiomyocytes in a Ca2+ imaging assay: Evaluation of 28 CiPA compounds at three test sites.

Jennifer B Pierson, I. Kopljar, R. Kettenhofen, 2019, Toxicological sciences : an official journal of the Society of Toxicology.