W. Biddison

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.

D. Wiley, U. Utz, D. Garboczi, 1998, Immunity.

HLA-A1 and HLA-A3 T cell epitopes derived from influenza virus proteins predicted from peptide binding motifs.

K. Parker, J. Coligan, W. Biddison, 1993, Journal of immunology.

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.

B M Baker, D. Wiley, D. Garboczi, 1999, Immunity.

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

Partho Ghosh, Don C. Wiley, D. Wiley, 1996, Nature.

The Structure and Stability of an HLA-A*0201/Octameric Tax Peptide Complex with an Empty Conserved Peptide-N-Terminal Binding Site1

Partho Ghosh, Brian M. Baker, Don C. Wiley, 2000, The Journal of Immunology.

T cell receptor recognition via cooperative conformational plasticity.

Brian M Baker, B. Baker, R. Davis-Harrison, 2006, Journal of molecular biology.

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

D. Nelson, R. Yarchoan, W. Biddison, 1985, Journal of immunology.

The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.

G. Shearer, W. Biddison, S. Shaw, 1980, Journal of immunology.

Thermodynamic and kinetic analysis of a peptide-class I MHC interaction highlights the noncovalent nature and conformational dynamics of the class I heterotrimer.

B. Baker, A. Binz, W. Biddison, 2003, Biochemistry.

Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene.

J. Wharton, D. Fan, W. Biddison, 1993, Cellular immunology.

beta-Endorphin augments the cytolytic activity and interferon production of natural killer cells.

R. Mandler, W. Biddison, S. Serrate, 1986, Journal of immunology.

Peptide specificity in the recognition of MHC class I by natural killer cell clones

Eric O Long, K. Parker, E. Ciccone, 1995, Science.

Structural studies of an HLA-A03 alloantigenic epitope defined by a human hybridoma antibody

Robert W. Anderson, J. Coligan, W. Maloy, 2006, Immunogenetics.

Mutations in the alpha 2 helix of HLA-A2 affect presentation but do not inhibit binding of influenza virus matrix peptide.

J. Coligan, V. Engelhard, W. Maloy, 1988, The Journal of experimental medicine.

Endogenous peptides with distinct amino acid anchor residue motifs bind to HLA-A1 and HLA-B8.

K. Parker, J. Coligan, J. Shiloach, 1994, Journal of immunology.

Physical and functional association of the T cell receptor and the T3 molecular complex on cytotoxic T cell clones that are differentially inhibitable by anti-T3 antibodies.

E. Leontsini, W. Biddison, T. Brown, 1986, Cellular immunology.

Peptide binding to HLA-A2 and HLA-B27 isolated from Escherichia coli. Reconstitution of HLA-A2 and HLA-B27 heavy chain/beta 2-microglobulin complexes requires specific peptides.

K. Parker, J. Coligan, U. Utz, 1992, The Journal of biological chemistry.

Peptide Binding Motifs for MHC Class I and II Molecules

R. Martin, W. Biddison, Roland Martin, 2000, Current protocols in immunology.

Subtypes of HLA-B27 detected by cytotoxic T lymphocytes and their role in self-recognition.

M. Breuning, W. Biddison, M. Engelsma, 1982, Human immunology.

Chemokine and matrix metalloproteinase secretion by myelin proteolipid protein-specific CD8+ T cells: potential roles in inflammation.

D. Taub, E. Connor, W. Biddison, 1997, Journal of immunology.

Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

J. Bonifacino, R. Klausner, W. Biddison, 1989, Nature.

Processing pathways for presentation of cytosolic antigen to MHC class II-restricted T cells

Eric O Long, R. Demars, W. Biddison, 1992, Nature.

Class II MHC molecules can use the endogenous pathway of antigen presentation

R. Klausner, W. Biddison, J. Nuchtern, 1990, Nature.

CD8 T Cell-Mediated HLA-A*0201-Restricted Cytotoxicity to Transaldolase Peptide 168–176 in Patients with Multiple Sclerosis

A. Perl, W. Biddison, K. Bánki, 2005 .

Strategic Mutations in the Class I Major Histocompatibility Complex HLA-A2 Independently Affect Both Peptide Binding and T Cell Receptor Recognition*

J. Beck, B. Baker, A. Binz, 2004, Journal of Biological Chemistry.

A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.

D. Nelson, W. Biddison, L. Rubin, 1985, Hybridoma.

HLA-B37 and HLA-A2.1 molecules bind largely nonoverlapping sets of peptides.

R. Anderson, J. Coligan, B. Carreno, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Skewed T-cell receptor repertoire in genetically identical twins correlates with multiple sclerosis

U. Utz, Roland Martin, D. McFarlin, 1993, Nature.

Induction of experimental allergic encephalomyelitis in the NIH minipig

J. Frank, H. McFarland, W. Biddison, 2000, Journal of Neuroimmunology.

Structural Features on Peptide / HLA-A 2 and T Cell Receptors Recognize Nonidentical Tax and M 1 Peptide / HLA-A 2-Specific Fabs

Avital Lev, Y. Reiter, W. Biddison, 2003 .

Possible involvement of the OKT4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of cytotoxic T lymphocytes specific for SB antigens

W. Biddison, S. Shaw, G. Goldstein, 1982, The Journal of experimental medicine.

DNA sequences of the genes that encode the CTL-defined HLA-A2 variants M7 and DK1

J. Coligan, D. Mattson, D. Handy, 2004, Immunogenetics.

DNA sequence of HLA-A11: Remarkable homology with HLA-A3 allows identification of residues involved in epitopes recognized by antibodies and T cells

J. Coligan, W. Biddison, M. L. Jelachich, 2004, Immunogenetics.

Analysis of HLA‐A3 Determinants Recognized by MHC‐Restricted and Alloreactive Cytotoxic T Lymphocytes Using Site‐Directed Mutagenesis a

J. Coligan, W. Biddison, M. L. Jelachich, 1988, Annals of the New York Academy of Sciences.

Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes. II. Variant DK1: evidence for a discrete CTL recognition region.

J. Strominger, M. Krangel, W. Biddison, 1983, Journal of immunology.

Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.

G. Shearer, W. Biddison, S. Shaw, 1981, Journal of immunology.

Two subgroups of HLA Bw44 defined by cell-mediated lympholysis that differ in Bw44 expression on platelets and in patterns of genetic linkage disequilibrium.

W. Biddison, S. Shaw, W. Tekolf, 1982, Journal of immunology.

Comparative structural analysis of HLA-A3 antigens distinguishable by cytotoxic T lymphocytes: variant E1.

J. Coligan, W. Biddison, A. E. Berger, 1985, Journal of immunology.

Comparative structural analysis of HLA-A2 antigens distinguishable by cytotoxic T lymphocytes: variants M7 and DR1.

J. Strominger, M. Krangel, S. Taketani, 1982, Biochemistry.

Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules.

J. Strominger, M. Krangel, G. Shearer, 1980, Human immunology.

Human autoreactive CD4+ T cell clones use perforin- or Fas/Fas ligand-mediated pathways for target cell lysis.

B. Hemmer, H. McFarland, R. Martin, 1997, Journal of immunology.

MHC Allele-Specific Molecular Features Determine Peptide/HLA-A2 Conformations That Are Recognized by HLA-A2-Restricted T Cell Receptors1

B. Baker, W. Biddison, R. Turner, 2002, The Journal of Immunology.

T Cell Receptors That Are Recognized by HLA-A 2-Restricted Determine Peptide / HLA-A 2 Conformations MHC Allele-Specific Molecular Features

B. Baker, W. Biddison, R. Turner, 2002 .

Delineation of immunologically and biochemically distinct HLA-A2 antigens.

J. Strominger, M. Krangel, W. Biddison, 1982, Journal of immunology.

Major histocompatibility complex-restricted H-Y-specific antibodies and cytotoxic T lymphocytes may recognize different self determinants

A. van Leeuwen, W. Biddison, E. Goulmy, 1982, The Journal of experimental medicine.

CD4 Expression and Function in HLA Class Il‐Specific T Cells

W. Biddison, S. Shaw, 1989, Immunological reviews.

Regulation of influenza virus-specific cytotoxic T cell responses by monoclonal antibody to a human T cell differentiation antigen.

T. Chang, G. Shearer, W. Biddison, 1981, Journal of immunology.

SB-Specific CTL Clones Exhibit Functional Heterogeneity in their Susceptibility to Blocking by Anti-T3 and Anti-T4 Antibodies

W. Biddison, S. Shaw, 1985 .

Distinct epitopes on the T8 molecule are differentially involved in cytotoxic T cell function.

W. Biddison, G. Goldstein, P. Rao, 1984, Human immunology.

Overlapping epitopes that are recognized by CD8+ HLA class I-restricted and CD4+ class II-restricted cytotoxic T lymphocytes are contained within an influenza nucleoprotein peptide.

J. Coligan, B. Carreno, W. Biddison, 1992, Journal of immunology.

Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens: evidence from studies of proliferative responses to SB antigens.

W. Biddison, S. Shaw, G. Goldstein, 1983, Journal of immunology.

Analysis of gene expression in mutiple sclerosis lesions using cDNA microarrays.

J. Trent, P. Munson, K. Becker, 1999, Annals of neurology.

Heterogeneity of T-cell receptor alpha-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis.

U. Utz, H. McFarland, R. Martin, 1994, Proceedings of the National Academy of Sciences of the United States of America.

MHC class I-restricted lysis of human oligodendrocytes by myelin basic protein peptide-specific CD8 T lymphocytes.

J. Antel, W. Biddison, A. Jurewicz, 1998, Journal of immunology.

Autoreactive CD8+ cell responses to human myelin protein-derived peptides

K. Parker, J. Coligan, W. Biddison, 1994, Journal of Neuroimmunology.

Measles virus-specific T4+ human cytotoxic T cell clones are restricted by class II HLA antigens.

H. McFarland, R. Hartzman, S. Jacobson, 1984, Journal of immunology.

Functional T lymphocyte immune deficiency in a population of homosexual men who do not exhibit symptoms of acquired immune deficiency syndrome.

G. Shearer, W. Biddison, L. J. Joseph, 1984, The Journal of clinical investigation.

Recognition by HLA-A2-restricted cytotoxic T lymphocytes of endogenously generated and exogenously provided synthetic peptide analogues of the influenza A virus matrix protein.

M. Bednarek, W. Biddison, B. Bush, 1993, Human immunology.

Virus-specific HLA Class II-restricted Cytotoxic T Cells

S. Jacobson, W. Biddison, 1986 .

The role of the human major histocompatibility complex in cytotoxic T-cell responses to virus-infected cells

W. Biddison, 2004, Journal of Clinical Immunology.

Human cytotoxic T-cell responses to type A and type B influenza viruses can be restricted by different HLA antigens. Implications for HLA polymorphism and genetic regulation

G. Shearer, W. Biddison, S. Shaw, 1980, The Journal of experimental medicine.

Differences in HLA antigen recognition by human influenza virus-immune cytotoxic T cells.

W. Biddison, S. Shaw, 1979, Journal of immunology.

HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus

W. Biddison, S. Shaw, Stephen Shaw, 1979, The Journal of experimental medicine.

Virus specificity of human influenza virus-immune cytotoxic T cells.

D. Nelson, W. Biddison, S. Shaw, 1979, Journal of immunology.

The Role of Amino Acid Position and Side Chain Structure in Serological and CTL-Defined Epitopes on the HLA-A2.1 Molecule

V. Engelhard, A. Krensky, W. Biddison, 1990 .

Phenotypes of human natural killer cell populations detected with monoclonal antibodies.

W. Biddison, K. Clouse, P. Kung, 1981, Journal of immunology.

The HLA-B14 peptide binding site can accommodate peptides with different combinations of anchor residues.

K. Parker, J. Coligan, J. Shiloach, 1994, The Journal of biological chemistry.

Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases.

J. Trent, B. Freidlin, K. Becker, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Differential effects of amino acid substitutions in the beta-sheet floor and alpha-2 helix of HLA-A2 on recognition by alloreactive viral peptide-specific cytotoxic T lymphocytes.

J. Coligan, D. Mattson, W. Maloy, 1989, Journal of immunology.

Characterization of monoclonal antibodies which recognize specific cell surface determinants on Salmonella typhimurium.

W. Biddison, M. Laveck, A. O’Brien, 1983, Advances in experimental medicine and biology.

Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA.

K. Becker, J. Nagle, K. Ozato, 1995, Gene.

Susceptibility of cytotoxic T lymphocyte (CTL) clones to inhibition by anti-T3 and anti-T4 (but not anti-LFA-1) monoclonal antibodies varies with the "avidity" of CTL-target interaction.

T. Springer, W. Biddison, S. Shaw, 1985, Journal of immunology.

Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens. Evidence from studies of CTL-target cell binding

W. Biddison, S. Shaw, G. Goldstein, 1984, The Journal of experimental medicine.

Site-directed mutagenesis of an HLA-A3 gene identifies amino acid 152 as crucial for major-histocompatibility-complex-restricted and alloreactive cytotoxic-T-lymphocyte recognition.

J. Coligan, W. Biddison, M. L. Jelachich, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Peptide-Specific CD8 T Lymphocytes Oligodendrocytes by Myelin Basic Protein MHC Class I-Restricted Lysis of Human

J. Antel, W. Biddison, A. Jurewicz, 1998 .

Possible involvement of the OKT4 molecule in T-cell recognition of class II HLA antigens.

W. Biddison, S. Shaw, Biddison We, 1983, Diagnostic immunology.

Specificity of peptide binding by the HLA-A2.1 molecule.

R. Anderson, J. Coligan, W. Maloy, 1989, Journal of immunology.

MHC Recognition by Hapten-Specific HLA-A2-Restricted CD8+ CTL

W. Biddison, S. Gagnon, R. Turner, 2003, The Journal of Immunology.

Human T-cell subset requirements for the production of specific anti-influenza virus antibodyin vitro

D. Nelson, R. Yarchoan, W. Biddison, 1982, Journal of Clinical Immunology.

Killing of measles virus-infected cells by human cytotoxic T cells

D. Nelson, W. Biddison, S. Shaw, 1982, Infection and immunity.

Preparative separation of human T cells reactive with the OKT4 monoclonal antibody.

G. Shearer, S. Sharrow, W. Biddison, 1981, International journal of immunopharmacology.

Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule.

J. Coligan, W. Biddison, R. Turner, 1988, Journal of immunology.

T‐cell Receptor Use in Multiple Sclerosis

U. Utz, H. McFarland, R. Martin, 1995, Annals of the New York Academy of Sciences.

Involvement of H-2L gene products in virus-immune T-cell recognition. Evidence for an H-2L-restricted T-cell response

P. Doherty, W. Biddison, R. Levy, 1978, The Journal of experimental medicine.

Analysis of gene expression in multiple sclerosis lesions using cDNA microarrays

J. Trent, P. Munson, K. Becker, 1999 .

T cell subpopulations required for the human cytotoxic T lymphocyte response to influenza virus: evidence for T cell help.

G. Shearer, S. Sharrow, W. Biddison, 1981, Journal of immunology.

Tyrosine phosphorylation of the human T cell antigen receptor zeta-chain: activation via CD3 but not CD2.

R. Klausner, P. Ross, L. Samelson, 1988, Journal of immunology.

Rapid isolation and characterization of 118 novel C2H2-type zinc finger cDNAs expressed in human brain.

K. Becker, J. Nagle, K. Ozato, 1995, Human Molecular Genetics.

Preparation and Culture of Human Lymphocytes

W. Biddison, 1998, Current protocols in cell biology.

Major histocompatibility complex molecules as virus receptors.

S. Jacobson, W. Biddison, 1984, Immunology today.

Generation of Continuously Growing B Cell Lines by Epstein‐Barr Virus Transformation

W. Biddison, 1999, Current protocols in cell biology.

Brief Definitive Report Identification of a Specific Hla Dr2 Ia Molecule as a Restriction Element for Measles Virus- Specific Hla Class Ii-restricted Cytotoxic T Cell Clones

H. McFarland, G. Nepom, S. Jacobson, 2003 .

Brief Definitive Report Identification of a Specific Hla Dr2 Ia Molecule as a Restriction Element for Measles Virus- Specific Hla Class Ii-restricted Cytotoxic T Cell Clones

H. McFarland, G. Nepom, S. Jacobson, 2022 .

Unusual phenotypes of human inducer T cells as measured by OKT4 and related monoclonal antibodies.

J. Bach, S. Sharrow, W. Biddison, 1981, Journal of immunology.

The kinetics of peptide binding to HLA-A2 and the conformation of the peptide-A2 complex can be determined by amino acid side chains on the floor of the peptide binding groove.

R. Anderson, J. Coligan, D. Mattson, 1990, International Immunology.

Corrections: Autoreactive CD8^+ T-Cell Responses to Human Myelin Protein- Derived Peptides

K. Parker, J. Coligan, H. McFarland, 1995 .

Human cytotoxic lymphocyte tryptase. Its purification from granules and the characterization of inhibitor and substrate specificity.

N. Sigal, M. Poe, W. Biddison, 1988, The Journal of biological chemistry.

Experimental Transfusion Reactions in Monkeys: Haemolytic, Coagulant and Renal Effects of Transfused Isoimmune IgG and IgM

S. Robboy, W. Biddison, C. E. Bell, 1972, British journal of haematology.

CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity.

R. Martin, R. Lichtenfels, W. Biddison, 1994, Journal of immunological methods.

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

Bernhard Hemmer, Ronald N. Germain, Roland Martin, 2003, Nature Immunology.

Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses

R. Webster, W. Biddison, P. C. Doherty, 1977, The Journal of experimental medicine.

C2H2-171 : A novel human cDNA representing a developmentally regulated poz domain/zinc finger protein preferentially expressed in brain

M. Polymeropoulos, K. Becker, J. Nagle, 1997, International Journal of Developmental Neuroscience.

Susceptibility for multiple sclerosis is determined, in part, by inheritance of a 175-kb region of the TcR Vβ chain locus and HLA class II genes

L. Hood, D. McFarlin, H. McFarland, 1993, Journal of Neuroimmunology.

Analysis of a sequenced cDNA library from multiple sclerosis lesions

K. Becker, D. Mattson, J. Powers, 1997, Journal of Neuroimmunology.

Combinatorial Peptide Libraries and Biometric Score Matrices Permit the Quantitative Analysis of Specific and Degenerate Interactions Between Clonotypic TCR and MHC Peptide Ligands1

R Simon, C. Pinilla, B. Hemmer, 2001, The Journal of Immunology.

Shapes of MHC Restriction Review

D. Garboczi, W. Biddison, 1999 .

Shapes of MHC restriction.

D. Garboczi, W. Biddison, 1999, Immunity.

The germline repertoire of T cell receptor β-chain genes in patients with chronic progressive multiple sclerosis

L. Hood, D. McFarlin, H. McFarland, 1989, Journal of Neuroimmunology.

Beta-chain gene rearrangements and V beta gene usage in DPw2-specific T cells.

D. Mattson, D. Singer, W. Biddison, 1987, Journal of immunology.

CD8+ myelin peptide-specific T cells can chemoattract CD4+ myelin peptide-specific T cells: importance of IFN-inducible protein 10.

D. Taub, W. Biddison, W. Cruikshank, 1998, Journal of immunology.

Cells : Importance of IFN-Inducible Protein 10 Myelin Peptide-Specific T + Chemoattract CD 4 Myelin Peptide-Specific T Cells Can + CD 8

D. Taub, W. Biddison, W. Cruikshank, 1997 .

Interferon regulatory factor-2 physically interacts with NF-κB in vitro and inhibits NF-κB induction of major histocompatibility class I and β2-microglobulin gene expression in transfected human neuroblastoma cells

K. Ozato, L. Carlson, G. Franzoso, 1995, Journal of Neuroimmunology.

Interferon regulatory factor-2 physically interacts with NF-kappa B in vitro and inhibits NF-kappa B induction of major histocompatibility class I and beta 2-microglobulin gene expression in transfected human neuroblastoma cells.

K. Ozato, L. Carlson, G. Franzoso, 1995, Journal of neuroimmunology.

Immunodominance of a low-affinity major histocompatibility complex-binding myelin basic protein epitope (residues 111-129) in HLA-DR4 (B1*0401) subjects is associated with a restricted T cell receptor repertoire.

D E Banks, J. Nagle, H. McFarland, 1997, The Journal of clinical investigation.

Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants.

Brian M Baker, K. M. Armstrong, B. Baker, 2005, Journal of molecular biology.

Cleavage of Transaldolase by Granzyme B Causes the Loss of Enzymatic Activity with Retention of Antigenicity for Multiple Sclerosis Patients

J. Lieberman, D. Martinvalet, A. Perl, 2010, The Journal of Immunology.

Cytotoxic T-cell responses in mice infected with influenza and vaccinia viruses vary in magnitude with H-2 genotype

J. Bennink, P. Doherty, B. Knowles, 1978, The Journal of experimental medicine.

Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population.

K. Parker, J. Coligan, J. Shiloach, 1995, Biochemistry.

Sequence motifs important for peptide binding to the human MHC class I molecule, HLA-A2.

K. Parker, M. Bednarek, J. Coligan, 1992, Journal of immunology.

Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection.

M. Daucher, A. Fauci, G. Pantaleo, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Endogenous peptides bound to HLA-A3 possess a specific combination of anchor residues that permit identification of potential antigenic peptides.

K. Parker, J. Coligan, J. Shiloach, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Diversity in fine specificity and T cell receptor usage of the human CD4+ cytotoxic T cell response specific for the immunodominant myelin basic protein peptide 87-106.

E. D. Robinson, J. Coligan, U. Utz, 1992, Journal of immunology.

Peptide recognition by two HLA-A2/Tax11-19-specific T cell clones in relationship to their MHC/peptide/TCR crystal structures.

D. Wiley, U. Utz, D. Garboczi, 1999, Journal of immunology.

Identification of an epitope derived from human proteolipid protein that can induce autoreactive CD8+ cytotoxic T lymphocytes restricted by HLA-A3: evidence for cross-reactivity with an environmental microorganism

K. Becker, K. Parker, J. Coligan, 1997, Journal of Neuroimmunology.

A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection.

Ettore Appella, E. Appella, Huanchen Wang, 2003, Immunity.

Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by Tax Peptide/Hla-A2–Specific T Cell Receptors

Brian M. Baker, Don C. Wiley, D. Wiley, 2001, The Journal of experimental medicine.

Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.

D. Wiley, U. Utz, D. Garboczi, 1996, Journal of immunology.

Characterization and specificity of murine anti-tumor cytotoxic effector cells within an ascitic tumor.

L. Manson, W. Biddison, E. Cowan, 1977, Journal of immunology.

Accumulation of human immunodeficiency virus‐specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection

M. Daucher, A. Fauci, G. Pantaleo, 1997, European journal of immunology.

Structural, biochemical, and biophysical studies of HLA-A2/altered peptide ligands binding to viral-peptide-specific human T-cell receptors.

B M Baker, D. Wiley, D. Garboczi, 1999, Cold Spring Harbor symposia on quantitative biology.

Human peptide transporter deficiency: importance of HLA-B in the presentation of TAP-independent EBV antigens.

J P Cazenave, H. Rammensee, S. Stevanović, 1997, Journal of immunology.

Analysis of the T-cell receptor repertoire of human T-cell leukemia virus type 1 (HTLV-1) Tax-specific CD8+ cytotoxic T lymphocytes from patients with HTLV-1-associated disease: evidence for oligoclonal expansion

U. Utz, S. Jacobson, W. Biddison, 1996, Journal of virology.

Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions

S. Ludwin, H. McFarland, W. Biddison, 2001, Journal of Neuroimmunology.

Binding and presentation of peptides derived from melanoma antigens MART-1 and glycoprotein-100 by HLA-A2 subtypes. Implications for peptide-based immunotherapy.

F. Marincola, E. Appella, M. Salgaller, 1996, Journal of immunology.

The germline repertoire of T-cell receptor beta-chain genes in patients with multiple sclerosis.

L. Hood, D. McFarlin, H. McFarland, 1989, Research in immunology.

Measurement of polyclonal and antigen-specific cytotoxic T cell function.

R. Martin, R. Lichtenfels, W. Biddison, 2001, Current protocols in immunology.

Pocket mutations of HLA-B27 show that anchor residues act cumulatively to stabilize peptide binding.

K. Parker, J. Coligan, W. Biddison, 1994, Biochemistry.

The peptide binding specificity of HLA class I molecules is largely allele-specific and non-overlapping.

J. Coligan, S. Koenig, B. Carreno, 1992, Molecular immunology.

Presentation of three different viral peptides, HTLV-1 Tax, HCMV gB, and influenza virus M1, is determined by common structural features of the HLA-A2.1 molecule.

J. Coligan, U. Utz, S. Koenig, 1992, Journal of immunology.

Residues in pockets B and F of HLA-B27 are critical in the presentation of an influenza A virus nucleoprotein peptide and influence the stability of peptide - MHC complexes.

B. Carreno, W. Biddison, C. Winter, 1993, International immunology.

Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide–HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections

D. Maric, S. Jacobson, Y. Yamano, 2003, Nature Medicine.

Human Major Histocompatibility Complex (MHC) Class I Molecules with Disulfide Traps Secure Disease-related Antigenic Peptides and Exclude Competitor Peptides*

J. Martinko, G. Linette, D. Fremont, 2008, Journal of Biological Chemistry.

CD8+ T Cell-Mediated HLA-A*0201-Restricted Cytotoxicity to Transaldolase Peptide 168–176 in Patients with Multiple Sclerosis1

A. Perl, W. Biddison, K. Bánki, 2005, The Journal of Immunology.

T cell recognition of an HLA-A2-restricted epitope derived from a cleaved signal sequence

Eric O Long, W. Biddison, W E Biddison, 1994, The Journal of experimental medicine.

Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

D. Wiley, B. Baker, W. Biddison, 2000, Immunity.

The 45 pocket of HLA-A2.1 plays a role in presentation of influenza virus matrix peptide and alloantigens.

S. Koenig, B. Carreno, W. Biddison, 1991, Journal of immunology.

The Effect of Human β2-Microglobulin on Major Histocompatibility Complex I Peptide Loading and the Engineering of a High Affinity Variant

Ryuji Kubota, Steven Jacobson, S. Jacobson, 1998, The Journal of Biological Chemistry.

Specific lysis of human immunodeficiency virus type 1-infected cells by a HLA-A3.1-restricted CD8+ cytotoxic T-lymphocyte clone that recognizes a conserved peptide sequence within the gp41 subunit of the envelope protein.

P. Earl, B. Moss, F. Ennis, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Peptide-N-Terminal Binding Site Complex with an Empty Conserved HLA-A * 0201 / Octameric Tax Peptide The Structure and Stability of an Biddison

D. Wiley, B. Baker, P. Ghosh, 2000 .

Tax and M1 Peptide/HLA-A2-Specific Fabs and T Cell Receptors Recognize Nonidentical Structural Features on Peptide/HLA-A2 Complexes 1

Avital Lev, Y. Reiter, W. Biddison, 2003, The Journal of Immunology.

Development of tumor cell resistance to syngeneic cell-mediated cytotoxicity during growth of ascitic mastocytoma P815Y.

W. Biddison, J. Palmer, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Extensive T cell receptor cross-reactivity on structurally diverse haptenated peptides presented by HLA-A2.

W. Biddison, S. Gagnon, R. Turner, 2006, Molecular immunology.

Prospective study of cytotoxic T lymphocyte responses to influenza and antibodies to human T lymphotropic virus-III in homosexual men. Selective loss of an influenza-specific, human leukocyte antigen-restricted cytotoxic T lymphocyte response in human T lymphotropic virus-III positive individuals wi

R. Gallo, G. Shearer, W. Biddison, 1985, The Journal of clinical investigation.

Human cytotoxic T cell responses to trinitrophenyl hapten and influenza virus. Diversity of restriction antigens and specificity of HLA-linked genetic regulation.

G. Shearer, W. Biddison, S. Shaw, 1980, The Journal of experimental medicine.

C2H2-546: a zinc finger protein differentially expressed in HTLV-1 infected T cells.

A. Dehejia, M. Polymeropoulos, K. Becker, 1997, Journal of neurovirology.

Molecular cloning and mapping of a novel developmentally regulated human C2H2-type zinc finger

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