K. Watson

发表

Identification of Novel Human Immunodeficiency Virus Type 1-Inhibitory Peptides Based on the Antimicrobial Peptide Database

Guangshun Wang, A. Peterkofsky, K. Watson, 2010, Antimicrobial Agents and Chemotherapy.

A potent novel anti-HIV protein from the cultured cyanobacterium Scytonema varium.

L. Pannell, M. Boyd, B. O’Keefe, 2003, Biochemistry.

Interaction of the transactivating protein HIV-1 tat with sulphated polysaccharides.

R. Edwards, D. Davies, N. Gooderham, 1999, Biochemical pharmacology.

Binaphthyl-based dicationic peptoids with therapeutic potential.

Ronald N. Jones, Michael H. Miller, J. Deadman, 2010, Angewandte Chemie.

Anti-Human Immunodeficiency Virus Type 1 Activities of Antimicrobial Peptides Derived from Human and Bovine Cathelicidins

Guangshun Wang, Guangshun Wang, K. Watson, 2008, Antimicrobial Agents and Chemotherapy.

Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase.

E. De Clercq, C. Pannecouque, E. Arnold, 2009, Journal of medicinal chemistry.

Development of a Comprehensive Human Immunodeficiency Virus Type 1 Screening Algorithm for Discovery and Preclinical Testing of Topical Microbicides

Brigitte E. Sanders-Beer, B. Sanders-Beer, R. Ptak, 2008, Antimicrobial Agents and Chemotherapy.

Vaginal Microbicide Gel for Delivery of IQP-0528, a Pyrimidinedione Analog with a Dual Mechanism of Action against HIV-1

C. Dezzutti, L. Rohan, K. Watson, 2011, Antimicrobial Agents and Chemotherapy.

Anti-Human Immunodeﬁciency Virus Type 1 Activities of Antimicrobial Peptides Derived from Human and Bovine Cathelicidins (cid:1)

Guangshun Wang, K. Watson, R. Buckheit, 2008 .

Extra-nuclear location of histones in activated human peripheral blood lymphocytes and cultured T-cells.

R. Edwards, D. Parmelee, D. Davies, 1995, Biochemical pharmacology.

The Structure-Activity Relationships of 2,4(1H,3H)-pyrimidinedione Derivatives as potent HIV type 1 and type 2 inhibitors

K. Watson, R. Buckheit, D. Kang, 2007, Antiviral chemistry & chemotherapy.

Association of human apolipoprotein E with lipoproteins secreted by transfected McA RH7777 cells.

G. Getz, L. Blachowicz, C. Reardon, 1998, Journal of lipid research.

Inhibition of Human Immunodeficiency Virus Type 1 by Triciribine Involves the Accessory Protein Nef

R. Ptak, K. Watson, R. Buckheit, 2010, Antimicrobial Agents and Chemotherapy.

Synthesis and anti-HIV activity of new metabolically stable alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors incorporating N-methoxy imidoyl halide and 1,2,4-oxadiazole systems.

E. De Clercq, C. Pannecouque, M. Cushman, 2007, Journal of medicinal chemistry.

In vitro and in vivo characterization of a potential universal placebo designed for use in vaginal microbicide clinical trials.

G. Doncel, Mark G. Lewis, J. Schwartz, 2005, AIDS research and human retroviruses.

Novel modifications in the alkenyldiarylmethane (ADAM) series of non-nucleoside reverse transcriptase inhibitors.

M. Cushman, K. Watson, R. Buckheit, 1999, Journal of medicinal chemistry.

Total synthesis of anibamine, a novel natural product as a chemokine receptor CCR5 antagonist.

K. Watson, R. Buckheit, Guo Li, 2007, Organic letters.

Synthesis, biological activity, and crystal structure of potent nonnucleoside inhibitors of HIV-1 reverse transcriptase that retain activity against mutant forms of the enzyme.

S. Hughes, E. Arnold, K. Das, 2007, Journal of medicinal chemistry.

Synthesis and biological evaluation of alkenyldiarylmethane HIV-1 non-nucleoside reverse transcriptase inhibitors that possess increased hydrolytic stability.

C. Pannecouque, E. Clercq, M. Cushman, 2007, Journal of medicinal chemistry.

Potent inhibition of HIV-1 entry by (s4dU)35.

J. Szöllősi, L. Fésüs, K. Watson, 2005, Virology.

SJ-3366, a Unique and Highly Potent Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1) That Also Inhibits HIV-2

E. White, J. Lee, K. Watson, 2001, Antimicrobial Agents and Chemotherapy.

Development of topical microbicides to prevent the sexual transmission of HIV.

K. Morrow, K. Watson, R. Buckheit, 2010, Antiviral research.

Comparative Evaluation of the Inhibitory Activities of a Series of Pyrimidinedione Congeners That Inhibit Human Immunodeficiency Virus Types 1 and 2

K. Watson, R. Buckheit, T. Hartman, 2007, Antimicrobial Agents and Chemotherapy.

Comparative Evaluation of Virus Transmission Inhibition by Dual-Acting Pyrimidinedione Microbicides Using the Microbicide Transmission and Sterilization Assay

K. Watson, R. Buckheit, Christa E. Buckheit, 2008, Antimicrobial Agents and Chemotherapy.

Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development.

I. Chaiken, K. Watson, R. Buckheit, 2005, Protein expression and purification.

HIV-1-trans-activating (Tat) protein: both a target and a tool in therapeutic approaches.

R. Edwards, K. Watson, Robert Edwards, 1999, Biochemical pharmacology.

Production of Human Monoclonal Antibodies Recognizing Cross-Reactive Determinants on Lipopolysaccharides

J. Larrick, G. Senyk, K. Watson, 1986 .

In Vitro Preclinical Testing of Nonoxynol-9 as Potential Anti-Human Immunodeficiency Virus Microbicide: a Retrospective Analysis of Results from Five Laboratories

F. Krebs, G. Doncel, C. Dezzutti, 2006, Antimicrobial Agents and Chemotherapy.

Histones located on the plasma membrane of T-cells.

D. Parmelee, D. Davies, N. Gooderham, 1994, Biochemical Society transactions.

Enzymatic triggered release of an HIV-1 entry inhibitor from prostate specific antigen degradable microparticles.

Russell J Stewart, Robert W Buckheit, R. Stewart, 2011, International journal of pharmaceutics.

Synthesis of substituted diarylmethylenepiperidines (DAMPs), a novel class of anti-HIV agents.

Y. Pommier, M. Cushman, Allison A. Johnson, 2002, Bioorganic & medicinal chemistry.

Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

E. De Clercq, C. Pannecouque, M. Cushman, 2009, European journal of medicinal chemistry.

Inhibition of tubulin polymerization by select alkenyldiarylmethanes.

E. De Clercq, C. Pannecouque, M. Cushman, 2008, Bioorganic & medicinal chemistry letters.

Binaphthyl-based dicationic peptoids with therapeutic potential.

Ronald N. Jones, Michael H. Miller, J. Deadman, 2010, Angewandte Chemie.

Vaginal Microbicide Gel for Delivery of IQP-0528, a Pyrimidinedione Analog with a Dual Mechanism of Action against HIV-1

C. Dezzutti, L. Rohan, K. Watson, 2011, Antimicrobial Agents and Chemotherapy.