C. Irwin

发表

LL-37 in periodontal health and disease and its susceptibility to degradation by proteinases present in gingival crevicular fluid.

Maelíosa T. C. McCrudden, W. Coulter, M. McCrudden, 2013, Journal of clinical periodontology.

The Host Defence Peptide LL-37 is Susceptible to Proteolytic Degradation by Wound Fluid Isolated from Foot Ulcers of Diabetic Patients

M. McCrudden, C. Irwin, F. Lundy, 2014, International Journal of Peptide Research and Therapeutics.

Invasive front grading: reliability and usefulness in the management of oral squamous cell carcinoma.

A. Leonard, C. Irwin, F. Sawair, 2003, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Regulation of fibroblast-induced collagen gel contraction by interleukin-1beta.

C. Irwin, J. Doogan, S. Schor, 2007, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Inter- and intra-site heterogeneity in the expression of fetal-like phenotypic characteristics by gingival fibroblasts: potential significance for wound healing.

M. McGurk, M. Picardo, P. Sloan, 1994, Journal of cell science.

Cyclosporin A regulates interleukin-1beta and interleukin-6 expression in gingiva: implications for gingival overgrowth.

C. Irwin, G. Linden, J. Marley, 1999, Journal of periodontology.

A connectivity mapping approach predicted acetylsalicylic acid (aspirin) to induce osteo/odontogenic differentiation of dental pulp cells.

I. About, C. Irwin, F. Lundy, 2020, International endodontic journal.

Matrix metalloproteinase‐8 activity in gingival crevicular fluid: development of a novel assay

C. Irwin, F. Lundy, G. Linden, 2017, Journal of periodontal research.

Natural Antimicrobials in the Dental Pulp.

C. Irwin, F. Lundy, G. Linden, 2020, Journal of endodontics.

The role of soluble interleukin (IL)-6 receptor in mediating the effects of IL-6 on matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 expression by gingival fibroblasts.

C. Irwin, P. Traynor, T. Cawston, 2002, Journal of periodontology.

Effects of LL-37 on Gingival Fibroblasts: A Role in Periodontal Tissue Remodeling?

Maelíosa T. C. McCrudden, M. McCrudden, C. Irwin, 2018, Vaccines.

Evaluation of the Ability of LL-37 to Neutralise LPS In Vitro and Ex Vivo

D. McAuley, M. Tunney, J. Elborn, 2011, PloS one.

Altered Toll-like Receptor 2-mediated Endotoxin Tolerance Is Related to Diminished Interferon β Production

W. Coulter, D. Fitzgerald, C. Irwin, 2011, The Journal of Biological Chemistry.

Effects of cytokines on gingival fibroblasts in vitro are modulated by the extracellular matrix.

M. Ferguson, C. Irwin, M. Ferguson, 1994, Journal of periodontal research.

Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review

L. Mcgarvey, C. Irwin, F. Lundy, 2021, BMC Oral Health.

The influence of transforming growth factor-beta1 gene polymorphisms on the severity of gingival overgrowth associated with concomitant use of cyclosporin A and a calcium channel blocker.

P. McNamee, A. Maxwell, C. Irwin, 2001, Journal of periodontology.

Neuropeptides regulate expression of angiogenic growth factors in human dental pulp fibroblasts.

C. Irwin, F. Lundy, G. Linden, 2009, Journal of endodontics.

Signal recognition particle receptor (SRPR) is downregulated in a rat model of cyclosporin A-induced gingival overgrowth.

J. Thompson, P. Robinson, C. Irwin, 1999, Journal of periodontal research.

Biodentine Reduces Tumor Necrosis Factor Alpha-induced TRPA1 Expression in Odontoblastlike Cells.

Maelíosa T. C. McCrudden, T. Curtis, I. About, 2016, Journal of endodontics.

Effective oral health in infective endocarditis: efficacy of high-street mouthwashes against the viridans group streptococci.

B. Prendergast, W. Coulter, M. Thornhill, 2014, Journal of investigative and clinical dentistry.

PAR-2 Regulates Dental Pulp Inflammation Associated with Caries

T. Curtis, I. About, C. Irwin, 2010, Journal of dental research.

Differential regulation of NPY and SP receptor expression in STRO-1+ve PDLSCs by inflammatory cytokines.

C. Irwin, F. Lundy, G. Linden, 2021, Journal of periodontal research.

Intrapregnancy non-surgical periodontal treatment and pregnancy outcome: a randomized controlled trial.

C. Irwin, G. Linden, M. Pirie, 2013, Journal of periodontology.

Phenotypic differences between oral and skin fibroblasts in wound contraction and growth factor expression

C. Irwin, F. Lundy, S. McKeown, 2006, Wound Repair and Regeneration.

Matrix Metalloproteinase-3 Differences in Oral and Skin Fibroblasts

C. Irwin, F. Lundy, S. McKeown, 2007, Journal of dental research.

The Host Defence Peptide LL-37 is Susceptible to Proteolytic Degradation by Wound Fluid Isolated from Foot Ulcers of Diabetic Patients

Maelíosa T. C. McCrudden, M. McCrudden, C. Irwin, 2014, International Journal of Peptide Research and Therapeutics.

Modulation of gingival epithelial phenotypes by interactions with regionally defined populations of fibroblasts.

I. Mackenzie, C. Irwin, P. Hyland, 2008, Journal of periodontal research.

Reduction in gingival overgrowth associated with conversion from cyclosporin A to tacrolimus.

A. Maxwell, C. Irwin, G. Linden, 2000, Journal of clinical periodontology.

Expression of EGF-receptors on epithelial and stromal cells of normal and inflamed gingiva.

M. Ferguson, C. Irwin, M. Ferguson, 1991, Journal of periodontal research.

Periodontal status and chronic obstructive pulmonary disease (COPD) exacerbations: a systematic review

L. Mcgarvey, C. Irwin, F. Lundy, 2021, BMC oral health.

TNF-α-induced p38MAPK activation regulates TRPA1 and TRPV4 activity in odontoblast-like cells.

Maelíosa T. C. McCrudden, T. Curtis, I. About, 2015, The American journal of pathology.

Human odontoblasts express functional thermo-sensitive TRP channels: Implications for dentin sensitivity

T. Curtis, I. About, C. Irwin, 2011, PAIN®.

Human dental pulp fibroblasts express the "cold-sensing" transient receptor potential channels TRPA1 and TRPM8.

T. Curtis, I. About, C. Irwin, 2011, Journal of endodontics.

The calcium channel blocker used with cyclosporin has an effect on gingival overgrowth.

A. Maxwell, C. Irwin, G. Linden, 2000, Journal of clinical periodontology.

Regulation of keratinocyte growth factor and scatter factor in cyclosporin-induced gingival overgrowth.

I. Mackenzie, C. Irwin, S. McKeown, 2004, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Cyclosporin associated gingival overgrowth in renal transplant recipients.

C. Irwin, G. Linden, J. Marley, 2008, Oral diseases.

p53, Cyclin D1, p21 (WAF1) and Ki-67 (MIB1) Expression at Invasive Tumour Fronts of Oral Squamous Cell Carcinomas and Development of Local Recurrence.

P. Maxwell, C. Irwin, A. Leonard, 2016, Asian Pacific journal of cancer prevention : APJCP.

Gingival fibroblast response to cyclosporin A and transforming growth factor β1

C. Irwin, J. James, G. Linden, 2010 .

Gingival fibroblast response to cyclosporin A and transforming growth factor beta 1.

C. Irwin, G. Linden, J. A. James, 1998, Journal of periodontal research.

The effects of cyclosporin on the collagenolytic activity of gingival fibroblasts.

C. Irwin, P. Traynor, G. Linden, 2003, Journal of periodontology.

Fracture repair of reptilian dermal bones: can reptiles form secondary cartilage?

M. Ferguson, C. Irwin, 1986, Journal of anatomy.

Subpopulations of fetal-like gingival fibroblasts: characterisation and potential significance for wound healing and the progression of periodontal disease.

D. Chisholm, J. Banyard, C. Irwin, 2008, Oral diseases.

Comparative effects of cyclosporin on glycosaminoglycan synthesis by gingival fibroblasts.

C. Irwin, J. Newell, 1997, Journal of periodontology.

Keratinocyte growth factor and scatter factor expression by regionally defined oral fibroblasts.

I. Mackenzie, C. Irwin, S. McKeown, 2003, European journal of oral sciences.

Sialylation of Porphyromonas gingivalis LPS and its effect on bacterial–host interactions

W. Coulter, C. Irwin, F. Lundy, 2017, Innate immunity.

Sialylation of Porphyromonas gingivalis lipopolysaccharides and its effect on bacterial-host interactions

W. Coulter, C. Irwin, F. Lundy, 2017 .

Strawberry gums'--a case of Wegener's granulomatosis

D. Mccluskey, C. Irwin, S. Napier, 1993, British Dental Journal.

Strawberry gums: a clinicopathological manifestation diagnostic of Wegener's granulomatosis?

D. Mccluskey, C. Irwin, S. Napier, 1993, Journal of clinical pathology.

Antimicrobial and immunomodulatory properties of PGLa-AM1, CPF-AM1, and magainin-AM1: Potent activity against oral pathogens

Maelíosa T. C. McCrudden, M. McCrudden, C. Irwin, 2014, Regulatory Peptides.

Substance P expression by human dental pulp fibroblasts: a potential role in neurogenic inflammation.

C. Irwin, F. Lundy, S. Killough, 2009, Journal of endodontics.

Dental pulp fibroblasts express neuropeptide Y Y1 receptor but not neuropeptide Y.

C. Irwin, F. Lundy, S. Killough, 2010, International endodontic journal.

Characterisation of eppin function: expression and activity in the lung

Maelíosa T. C. McCrudden, D. Timson, D. McAuley, 2017, European Respiratory Journal.

The cytotoxic effects of human neutrophil peptide-1 (HNP1) and lactoferrin on oral squamous cell carcinoma (OSCC) in vitro.

Fionnuala T Lundy, J. Nelson, C. Irwin, 2006, Oral oncology.

Construction of large area organotypical cultures of oral mucosa and skin.

I. Mackenzie, C. Irwin, M. Locke, 2003, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Regulation of HGF and SDF-1 expression by oral fibroblasts--implications for invasion of oral cancer.

A. Daly, C. Irwin, L. McIlreavey, 2008, Oral oncology.

The neutralising and stimulatory effects of antimicrobial peptide LL-37 in human gingival fibroblasts.

K. Mills, C. Irwin, M. Dellett, 2023, Archives of oral biology.

Interferon-γ stimulates CD14, TLR2 and TLR4 mRNA expression in gingival fibroblasts increasing responsiveness to bacterial challenge.

W. Coulter, C. Irwin, F. Lundy, 2016, Archives of oral biology.

The effects of culture environment on the response of human gingival fibroblasts to cyclosporin A.

C. Irwin, G. Linden, J. A. James, 1995, The Journal of Periodontology.

Phenotypic differences in growth, matrix synthesis and response to nifedipine between fibroblasts derived from clinically healthy and overgrown gingival tissue.

C. Irwin, K. McKevitt, 1995, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

Design, characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease.

W. Coulter, D. Jones, A. F. Brown, 2000, Journal of controlled release : official journal of the Controlled Release Society.

The role of IL-6 in the pathogenesis of periodontal disease.

C. Irwin, T. Myrillas, C. Irwin, 2008, Oral diseases.

Altered Toll-like Receptor 2-mediated Endotoxin Tolerance Is Related to Diminished Interferon β Production

W. Coulter, D. Fitzgerald, C. Irwin, 2011, The Journal of Biological Chemistry.