H. Itoh

发表

Discovery of gramicidin A analogues with altered activities by multidimensional screening of a one-bead-one-compound library

K. Sekimizu, H. Hamamoto, Suresh Panthee, 2020, Nature Communications.

Enantioselective total synthesis of vicenistatin, a novel 20-membered macrocyclic lactam antitumor antibiotic

T. Eguchi, K. Kakinuma, H. Itoh, 2002 .

Design, synthesis and functional analysis of dansylated polytheonamide mimic: an artificial peptide ion channel.

M. Kreir, S. Matsuoka, H. Itoh, 2012, Journal of the American Chemical Society.

Structural permutation of potent cytotoxin, polytheonamide B: discovery of cytotoxic Peptide with altered activity.

H. Itoh, M. Inoue, Hiroaki Itoh, 2013, ACS medicinal chemistry letters.

Raoultella electrica sp. nov., isolated from anodic biofilms of a glucose-fed microbial fuel cell.

S. Okabe, A. Hiraishi, H. Itoh, 2014, International journal of systematic and evolutionary microbiology.

Solid-Phase Total Synthesis of Yaku'amide B Enabled by Traceless Staudinger Ligation.

K. Kamiya, H. Itoh, M. Inoue, 2020, Angewandte Chemie.

Total Synthesis and Biological Mode of Action of WAP-8294A2: A Menaquinone-Targeting Antibiotic.

K. Sekimizu, H. Hamamoto, Suresh Panthee, 2017, The Journal of organic chemistry.

The total synthesis and functional evaluation of fourteen stereoisomers of yaku'amide B. The importance of stereochemistry for hydrophobicity and cytotoxicity.

H. Itoh, M. Inoue, Takefumi Kuranaga, 2016, Organic & biomolecular chemistry.

18O/16O-Encoding Strategy for Microscale Stereochemical Determination of Peptidic Natural Products.

H. Itoh, M. Inoue, Aoi Takeuchi, 2021, Chemistry, an Asian journal.

Antibody-mediated functional control of a dansylated polytheonamide mimic.

H. Itoh, M. Inoue, Hiroaki Itoh, 2014, Chemical communications.

Control of the cytotoxicity of dansylated polytheonamide mimic, an artificial peptide ion channel, by modification of the N-terminal structure

H. Itoh, M. Inoue, Takefumi Kuranaga, 2014 .

Solid‐Phase Total Synthesis of Yaku'amide B Enabled by Traceless Staudinger Ligation

K. Kamiya, H. Itoh, M. Inoue, 2020, Angewandte Chemie.

Biological Effects of a Simplified Synthetic Analogue of Ion-Channel-Forming Polytheonamide B on Plasma Membrane and Lysosomes.

H. Itoh, M. Inoue, Yun‐Wei Xue, 2019, Chemistry.

The effect of sulfur stereochemistry of l-β,β-dimethylmethionine S-oxide on the physicochemical properties of truncated polytheonamides

N. Shinohara, S. Matsuoka, H. Itoh, 2010 .

Comprehensive Structure-Activity Relationship Studies of Macrocyclic Natural Products Enabled by Their Total Syntheses.

H. Itoh, M. Inoue, Hiroaki Itoh, 2019, Chemical reviews.

Full solid-phase total synthesis of macrocyclic natural peptides using four-dimensionally orthogonal protective groups.

H. Itoh, M. Inoue, Hiroaki Itoh, 2019, Organic & biomolecular chemistry.

Divergent Solid-Phase Synthesis and Biological Evaluation of Yaku'amide B and Its Seven E/Z Isomers.

K. Kamiya, H. Itoh, M. Inoue, 2020, Chemistry.

Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E

K. Sekimizu, H. Hamamoto, Suresh Panthee, 2019, Nature Communications.

Total synthesis of the large non-ribosomal peptide polytheonamide B.

N. Shinohara, S. Matsuoka, H. Itoh, 2010, Nature chemistry.

Dual Chemical Modification of a Polytheonamide Mimic: Rational Design and Synthesis of Ion-Channel-Forming 48-mer Peptides with Potent Cytotoxicity.

H. Itoh, M. Inoue, S. Matsutaka, 2016, Chemistry.

Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus

K. Sekimizu, H. Hamamoto, A. Miyashita, 2021, Nature Communications.

Unified Total Synthesis of Five Bufadienolides.

H. Itoh, M. Inoue, Shinsuke Shimizu, 2020, Organic letters.

Enantioselective and convergent synthesis of the 20-membered lactam aglycon of vicenistatin antitumor antibiotic.

T. Eguchi, K. Kakinuma, H. Itoh, 1998, The Journal of antibiotics.

Selective Modification of the N‐Terminal Structure of Polytheonamide B Significantly Changes its Cytotoxicity and Activity as an Ion Channel

N. Shinohara, S. Matsuoka, H. Itoh, 2012, ChemMedChem.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system

I. Shimada, T. Mizukoshi, H. Itoh, 2018, Journal of Biomolecular NMR.

Deuteration and selective labeling of alanine methyl groups of β2-adrenergic receptor expressed in a baculovirus-insect cell expression system

I. Shimada, T. Mizukoshi, H. Itoh, 2018, Journal of biomolecular NMR.

Total Synthesis and Functional Evaluation of Fourteen Derivatives of Lysocin E: Importance of Cationic, Hydrophobic, and Aromatic Moieties for Antibacterial Activity.

K. Sekimizu, H. Hamamoto, T. Kaji, 2016, Chemistry.

Chemical construction and structural permutation of potent cytotoxin polytheonamide B: discovery of artificial peptides with distinct functions.

H. Itoh, M. Inoue, Hiroaki Itoh, 2013, Accounts of chemical research.

Solid-Phase Total Synthesis and Dual Mechanism of Action of the Channel-Forming 48-mer Peptide Polytheonamide B.

H. Itoh, M. Inoue, Atsushi Hayata, 2018, Journal of the American Chemical Society.

Total Synthesis and Biological Evaluation of 19-Hydroxysarmentogenin-3 -O-α-l-rhamnoside, Trewianin, and Their Aglycons.

N. Aoki, D. Urabe, H. Itoh, 2018, The Journal of organic chemistry.

Development of a high-throughput strategy for discovery of potent analogues of antibiotic lysocin E

K. Sekimizu, H. Hamamoto, Suresh Panthee, 2019, Nature Communications.

Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR

I. Shimada, H. Itoh, M. Inoue, 2020, Nature Communications.

Target Identification of Yaku'amide B and Its Two Distinct Activities against Mitochondrial FoF1-ATP Synthase.

S. Dan, H. Itoh, M. Inoue, 2018, Journal of the American Chemical Society.