H. Georgescu

发表

The biochemical and histological effects of artificial ligament wear particles: In vitro and in vivo studies

Freddie H. Fu, C. Evans, E. Olson, 1988, The American journal of sports medicine.

Herniated Cervical Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin‐6, and Prostaglandin E2

James D. Kang, H. Georgescu, C H Evans, 1995, Spine.

Herniated Lumbar Intervertebral Discs Spontaneously Produce Matrix Metalloproteinases, Nitric Oxide, Interleukin-6, and Prostaglandin E2

James D. Kang, W. Donaldson, C. Evans, 1996, Spine.

Observations on the senescence of cells derived from articular cartilage

C. Evans, H. Georgescu, 1983, Mechanisms of Ageing and Development.

Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRβ tyrosine phosphorylation

L. Miller, C. Evans, H. Georgescu, 2000 .

Nitric oxide inhibits chondrocyte response to IGF-I: inhibition of IGF-IRbeta tyrosine phosphorylation.

C. Evans, H. Georgescu, E. Levicoff, 2000, American journal of physiology. Cell physiology.

The effects of age on rabbit MCL fibroblast matrix synthesis in response to TGF-β 1 or EGF

S. Woo, M. Deie, C. Allen, 1997, Mechanisms of Ageing and Development.

The induction of IL-1 by freeze-dried ethylene oxide-treated bone-patellar tendon-bone allograft wear particles: an in vitro study.

Freddie H. Fu, C. Evans, H. Georgescu, 1993, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

The synovial production of collagenase and chondrocyte activating factors in response to cobalt

C. Evans, H. Georgescu, C. Evans, 1988, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Nitric oxide mediates suppression of cartilage proteoglycan synthesis by interleukin-1.

C. Evans, H. Georgescu, M. Stefanovic-Racic, 1994, Biochemical and biophysical research communications.

Characterization of Intervertebral Disc Aging: Longitudinal Analysis of a Rabbit Model by Magnetic Resonance Imaging, Histology, and Gene Expression

James D. Kang, L. Gilbertson, G. Sowa, 2008, Spine.

Inducible synthesis of collagenase and other neutral metalloproteinases by cells of aortic origin.

D. Steed, M. Webster, C. Evans, 1991, The Journal of surgical research.

Cyclic tensile stress exerts antiinflammatory actions on chondrocytes by inhibiting inducible nitric oxide synthase.

R. Gassner, S. Agarwal, C. Evans, 1999, Journal of immunology.

by Inhibiting Inducible Nitric Oxide Synthase Antiinflammatory Actions on Chondrocytes Cyclic Tensile Stress Exerts

R. Gassner, S. Agarwal, M. Buckley, 1999 .

The synovial activation of chondrocytes: evidence for complex cytokine interactions involving a possible novel factor.

G. Bandara, C. Evans, H. Georgescu, 1992, Biochimica et biophysica acta.

In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy.

J. Pelletier, J. Martel-Pelletier, P. Robbins, 1997, Arthritis and rheumatism.

Intraarticular expression of biologically active interleukin 1-receptor-antagonist protein by ex vivo gene transfer.

G. Bandara, P. Robbins, J. Glorioso, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide.

T. Billiar, R. Simmons, C. Evans, 1991, Journal of immunology.

Constitutive intra-articular expression of human IL-1 beta following gene transfer to rabbit synovium produces all major pathologies of human rheumatoid arthritis.

Simon C Watkins, E. Lechman, P. Robbins, 1997, Journal of immunology.

Nitric oxide synthesis and its regulation by rabbit synoviocytes.

C. Evans, H. Georgescu, M. Stefanovic-Racic, 1994, The Journal of rheumatology.

Does Nitric Oxide Help Explain the Differential Healing Capacity of the Anterior Cruciate, Posterior Cruciate, and Medial Collateral Ligaments?*

Freddie H. Fu, C. Evans, H. Georgescu, 2000, The American journal of sports medicine.

p38 MAPK inhibition modulates rabbit nucleus pulposus cell response to IL‐1

James D. Kang, L. Gilbertson, G. Sowa, 2008, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

p38 MAPK Inhibition in Nucleus Pulposus Cells: A Potential Target for Treating Intervertebral Disc Degeneration

James D. Kang, L. Gilbertson, G. Sowa, 2007, Spine.

Gene transfer to synoviocytes: prospects for gene treatment of arthritis.

G. Bandara, P. Robbins, J. Glorioso, 1992, DNA and cell biology.

Effects of immortalization upon the induction of matrix metalloproteinases in rabbit synovial fibroblasts.

P. Robbins, C. Evans, H. Georgescu, 1996, Experimental cell research.

Characterisation of chondrocyte activation in response to cytokines synthesised by a synovial cell line.

C. Evans, H. Georgescu, D. Mendelow, 1988, Biochimica et biophysica acta.

Chondrocyte activation in response to factor(s) produced by a continuous line of lapine synovial fibroblasts.

C. Evans, H. Georgescu, S. Watanabe, 1986, Experimental cell research.

Synovial protein kinase C and its apparent insensitivity to interleukin-1.

L. Traub, C. Evans, H. Georgescu, 1992, European journal of biochemistry.

In Vitro and in Vivo Testing of a Novel Regulatory System for Gene Therapy for Intervertebral Disc Degeneration

James D. Kang, G. Sowa, N. Vo, 2011, Spine.

Suppression of intra-articular responses to interleukin-1 by transfer of the interleukin-1 receptor antagonist gene to synovium.

P. Robbins, C. Evans, H. Georgescu, 1994, Gene therapy.

Differentiation of Intervertebral Notochordal Cells Through Live Automated Cell Imaging System In Vitro

James D. Kang, G. Sowa, N. Vo, 2009, Spine.

Generation of nitric oxide by lapine meniscal cells and its effect on matrix metabolism: Stimulation of collagen production by arginine

C. Evans, H. Georgescu, M. Stefanovic-Racic, 1998, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Chondrocyte activation by interleukin-1: analysis of the synergistic properties of fibroblast growth factor and phorbol myristate acetate.

G. Bandara, C. Evans, H. Georgescu, 1989, Archives of biochemistry and biophysics.

Enhanced endocytosis by aging chondrocytes and fibroblasts

C. Evans, H. Georgescu, R. P. Edwards, 1984, Experimental Gerontology.

Chondrocyte activation by a putative interleukin-1 derived from lapine polymorphonuclear leukocytes.

D. Kuhns, C. Evans, H. Georgescu, 1989, Archives of biochemistry and biophysics.

Induction of collagenase mRNA in lapine articular chondrocytes by synovial factors and interleukin-1.

G. Bandara, C. Brinckerhoff, C. Evans, 1988, Archives of biochemistry and biophysics.

Nitric oxide inhibition of IGF‐1 stimulated proteoglycan synthesis: Role of cGMP

H. Georgescu, R. Studer, S. Melhem, 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Genetic enhancement of matrix synthesis by articular chondrocytes: comparison of different growth factor genes in the presence and absence of interleukin-1.

P. Robbins, C. Evans, B. Johnstone, 2000, Arthritis and rheumatism.

Toward a Biochemical Understanding of Human Intervertebral Disc Degeneration and Herniation: Contributions of Nitric Oxide, Interleukins, Prostaglandin E2, and Matrix Metalloproteinases

James D. Kang, H. Georgescu, C. Evans, 1997, Spine.

Approaches to enhancing the retroviral transduction of human synoviocytes

P. Robbins, C. Evans, H. Georgescu, 2001, Arthritis research.

HIG-82: An established cell line from rabbit periarticular soft tissue, which retains the “activatable” phenotype

C. Evans, H. Georgescu, D. Mendelow, 1988, In Vitro Cellular & Developmental Biology.

Gene Transfer of the Catabolic Inhibitor TIMP-1 Increases Measured Proteoglycans in Cells from Degenerated Human Intervertebral Discs

Lars G. Gilbertson, Paul Robbins, James D. Kang, 2003, Spine.

Trisomy 7 in synovial fibroblasts obtained from arthritic joints

S. Gollin, C. Evans, H. Georgescu, 1999, Inflammation Research.

The role of AP-1 in matrix metalloproteinase gene expression

C. Evans, H. Georgescu, C. Lin, 1993, Agents and Actions.

Synovial activation of chondrocytes: Evidence for complex cytokine interactions

G. Bandara, C. Evans, H. Georgescu, 1991, Agents and Actions.

Interleukin-1 and synovial protein kinase C: Identification of a novel, 35 kDa cytosolic substrate

L. Traub, C. Evans, H. Georgescu, 1991, Agents and Actions.

Suppression of antigen-induced arthritis in rabbits by ex vivo gene therapy.

P. Robbins, C. Evans, H. Georgescu, 1996, Journal of immunology.

Increased matrix synthesis following adenoviral transfer of a transforming growth factor β1 gene into articular chondrocytes

P. Robbins, C. Evans, B. Johnstone, 2000, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Direct gene delivery to synovium. An evaluation of potential vectors in vitro and in vivo.

G. Bandara, P. Robbins, C. Evans, 1996, Arthritis and rheumatism.

Particle‐induced synthesis of collagenase by synovial fibroblasts: An immunocytochemical study

Freddie H. Fu, F H Fu, P. Greis, 1994, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Effect of growth factors on matrix synthesis by ligament fibroblasts

S. Woo, H. Georgescu, C. Niyibizi, 1997, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Effect of growth factors on the proliferation of ligament fibroblasts from skeletally mature rabbits.

S. Woo, C. Kwoh, C. Evans, 1997, Connective tissue research.

Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments

C. Kwoh, C. Evans, H. Georgescu, 1995, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Nitric oxide inhibits the synthesis of type-II collagen without altering Col2A1 mRNA abundance: prolyl hydroxylase as a possible target.

P. Hebda, C. Evans, H. Georgescu, 1997, The Biochemical journal.

Chondrocyte activation by interleukin-1: Synergism with fibroblast growth factor and phorbol myristate acetate

G. Bandara, C. Evans, H. Georgescu, 1989, Agents and Actions.

Ex vivo gene transfer to chondrocytes in full-thickness articular cartilage defects: a feasibility study.

P. Robbins, C. Evans, J. Suh, 1997, Osteoarthritis and cartilage.

Nitric oxide and energy production in articular chondrocytes

C. Evans, H. Georgescu, J. Stadler, 1994, Journal of cellular physiology.

Evidence that responses of articular chondrocytes to interleukin-1 and basic fibroblast growth factor are not mediated by protein kinase C.

C. Evans, H. Georgescu, K. Hulkower, 1991, The Biochemical journal.

Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: The use of different viral vectors and the effects of injury

S. Woo, C. Evans, M. Deie, 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Synovial cell transplants for gene transfer to joints.

G. Bandara, P. Robbins, C. Evans, 1992, Transplantation proceedings.

Inhibition of transforming growth factor beta production by nitric oxide-treated chondrocytes: implications for matrix synthesis.

C. Evans, H. Georgescu, C H Evans, 1999, Arthritis and rheumatism.

Studies on the autocrine activation of a synovial cell line

C. Evans, M. Baratz, H. Georgescu, 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

Altered patterns of protein phosphorylation in articular chondrocytes treated with interleukin‐1 or synovial cytokines

C. Evans, H. Georgescu, K. Hulkower, 1989, FEBS letters.

Protein kinase C and chondrocyte activation

C. Evans, H. Georgescu, K. Hulkower, 1989, Agents and Actions.

LIVE CELL IMAGING OF NOTOCHORDAL CELLS FROM THE RABBIT NUCLEUS PULPOSUS DEMONSTRATING DIFFERENTIATION AND INTERACTION WITH CHONDROCYTIC CELLS

James D. Kang, G. Sowa, N. Vo, 2008 .

INTRAARTICULAR EXPRESSION OF THE INTERLEUKIN-1 RECEPTOR ANTAGONIST PROTEIN BY EXVIVO GENE-TRANSFER

G. Bandara, P. Robbins, J. Glorioso, 1993 .

Cycloheximide inhibits the induction of collagenase mRNA in chondrocytes exposed to synovial factors or recombinant interleukin-1

C. Evans, H. Georgescu, S. Phillips, 1989, Agents and Actions.

Modulation of chondrocyte proteoglycan synthesis by endogeneously produced nitric oxide

C. Evans, H. Georgescu, D. Taşkıran, 1995, Inflammation Research.

Interleukin-1α as an autocrine regulator in rabbit synovial fibroblasts

C. Evans, H. Georgescu, J. M. Engle, 1997, Inflammation Research.