E. Manuel

发表

Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity

Wei Liu, B. Badie, Dongchang Zhao, 2010, Clinical Cancer Research.

Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer Leading to Reductions in Immunosuppressive Subsets and Tumor Growth

B. Blazar, E. Manuel, N. Ebelt, 2021, Cancers.

Effective cancer vaccine platform based on attenuated salmonella and a type III secretion system.

Daofeng Liu, M. Hensel, Amy N. Courtney, 2014, Cancer research.

Collagenase-Expressing Salmonella Targets Major Collagens in Pancreatic Cancer and Improves Immune Checkpoint Blockade

B. Blazar, E. Manuel, N. Ebelt, 2021 .

Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice

B. Badie, Leying Zhang, E. Manuel, 2012, Clinical Cancer Research.

Systemic delivery of Salmonella typhimurium transformed with IDO shRNA enhances intratumoral vector colonization and suppresses tumor growth.

B. Blazar, E. Manuel, D. Diamond, 2012, Cancer research.

Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors

T. Ludwig, J. Chen, M. D'Apuzzo, 2015, Cancer Immunology Research.

Targeting desmoplasia in pancreatic cancer as an essential first step to effective therapy

E. Manuel, N. Ebelt, Vic Zamloot, 2020, Oncotarget.

Contribution of T-Cell Receptor Repertoire Breadth to the Dominance of Epitope-Speciﬁc CD8 (cid:1) T-Lymphocyte Responses (cid:1)

B. Torbett, J. Schmitz, M. Kuroda, 2006 .

Evaluation of innate and adaptive immunity contributing to the antitumor effects of PD1 blockade in an orthotopic murine model of pancreatic cancer

M. D'Apuzzo, B. Blazar, E. Manuel, 2016, Oncoimmunology.

Development of an Effective Cancer Vaccine Using Attenuated Salmonella and Type III Secretion System to Deliver Recombinant Tumor-Associated Antigens Running title : Bacterial genes enable design of effective cancer vaccine

Daofeng Liu, M. Hensel, Amy N. Courtney, 2014 .

Developing Effective Salmonella-based Approaches to Treat Pancreatic Cancer

J. Chen, E. Manuel, D. Diamond, 2016, Pancreatic disorders & therapy.

Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model

Hang Gao, B. Badie, J. Berlin, 2016, PloS one.

Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Restructures the Immune Contexture to Improve Checkpoint Blockade Efficacy

R. Salgia, B. Blazar, E. Manuel, 2020, Biomedicines.

Restructuring of the Immune Contexture Improves Checkpoint Blockade Efficacy in Murine Lung Cancer

R. Salgia, B. Blazar, E. Manuel, 2020, bioRxiv.

Targeted Depletion of Hyaluronic Acid Mitigates Murine Breast Cancer Growth

E. Manuel, N. Ebelt, Vic Zamloot, 2022, Cancers.

Hyaluronidase-Expressing Salmonella Effectively Targets Tumor-Associated Hyaluronic Acid in Pancreatic Ductal Adenocarcinoma

E. Manuel, N. Ebelt, E. Zuniga, 2019, Molecular Cancer Therapeutics.

5-Azacytidine-Mediated Modulation of the Immune Microenvironment in Murine Acute Myeloid Leukemia

E. Manuel, N. Ebelt, 2022, Cancers.

Unraveling the crosstalk between melanoma and immune cells in the tumor microenvironment.

E. Manuel, N. Ebelt, M. Marzagalli, 2019, Seminars in cancer biology.

Enhancement of cancer vaccine therapy by systemic delivery of a tumor-targeting Salmonella-based STAT3 shRNA suppresses the growth of established melanoma tumors.

M. Hensel, E. Manuel, D. Diamond, 2011, Cancer research.

Dominant CD8+ T-Lymphocyte Responses Suppress Expansion of Vaccine-Elicited Subdominant T Lymphocytes in Rhesus Monkeys Challenged with Pathogenic Simian-Human Immunodeficiency Virus

M. Lifton, N. Letvin, M. Seaman, 2009, Journal of Virology.

Cyclin-dependent kinase inhibitor indirubin-3′-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies

L. Meijer, K. Münger, David C. Lee, 2004, Oncogene.

Contribution of T-Cell Receptor Repertoire Breadth to the Dominance of Epitope-Specific CD8+ T-Lymphocyte Responses

B. Torbett, J. Schmitz, M. Kuroda, 2006, Journal of Virology.

Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform

Xiwei Wu, E. Manuel, D. Diamond, 2020, Nature Communications.

Use of Molecular Beacons for Rapid, Real-Time, Quantitative Monitoring of Cytotoxic T-Lymphocyte Epitope Mutations in Simian Immunodeficiency Virus

N. Letvin, D. Barouch, E. Manuel, 2005, Journal of Clinical Microbiology.

Vaccination Reduces Simian-Human Immunodeficiency Virus Sequence Reversion through Enhanced Viral Control

M. Lifton, N. Letvin, E. Manuel, 2010, Journal of Virology.

Diverse Cross-Reactive Potential and Vβ Gene Usage of an Epitope-Specific Cytotoxic T-Lymphocyte Population in Monkeys Immunized with Diverse Human Immunodeficiency Virus Type 1 Env Immunogens

N. Letvin, M. Seaman, E. Manuel, 2009, Journal of Virology.

Heterologous Prime/Boost Immunization With p53-based Vaccines Combined With Toll-like Receptor Stimulation Enhances Tumor Regression

V. Shahabi, E. Manuel, D. Diamond, 2010, Journal of immunotherapy.

Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development.

P. Barry, J. Longmate, E. Manuel, 2009, Virology.

Desmoplasia and oncogene driven acinar-to-ductal metaplasia are concurrent events during acinar cell-derived pancreatic cancer initiation in young adult mice

E. Manuel, D. Diamond, H. Shih, 2019, PloS one.

The helix–loop–helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers

Karl Münger, K. Münger, S. Duensing, 2004, Oncogene.

Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses.

E. Manuel, D. Diamond, Zhongde Wang, 2010, Virology.

TLR9 expression and secretion of LIF by prostate cancer cells stimulates accumulation and activity of polymorphonuclear MDSCs

Yate-Ching Yuan, M. Kortylewski, S. Pal, 2017, Journal of leukocyte biology.

Development of a Multi-Antigenic SARS-CoV-2 Vaccine Using a Synthetic Poxvirus Platform

Xiwei Wu, E. Manuel, D. Diamond, 2020, Research square.

Development of a Synthetic Poxvirus-Based SARS-CoV-2 Vaccine

Xiwei Wu, E. Manuel, D. Diamond, 2020, bioRxiv.

Utilizing Salmonella to treat solid malignancies

E. Manuel, N. Ebelt, 2017, Journal of surgical oncology.

Salmonella-Mediated Therapy Targeting Indoleamine 2, 3-Dioxygenase 1 (IDO) Activates Innate Immunity and Mitigates Colorectal Cancer Growth

B. Blazar, E. Manuel, D. Diamond, 2019, Cancer Gene Therapy.

Tumor growth control with IDO-silencing Salmonella--reply.

B. Blazar, E. Manuel, D. Diamond, 2013, Cancer research.

Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model

E. Manuel, D. Diamond, J. Ellenhorn, 2010, Cancer Immunology, Immunotherapy.

Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS

A. Bild, Hanlin Gao, Prakash Kulkarni, 2019, bioRxiv.

Survivin the battle against immunosuppression

E. Manuel, D. Diamond, J. Ellenhorn, 2012, Oncoimmunology.

5-Azacytidine Potentiates Anti-tumor Immunity in a Model of Pancreatic Ductal Adenocarcinoma

E. Manuel, D. Diamond, N. Ebelt, 2020, Frontiers in Immunology.

A road less traveled paved by IDO silencing

E. Manuel, D. Diamond, 2013, Oncoimmunology.

Clonal Focusing of Epitope-Specific CD8+ T Lymphocytes in Rhesus Monkeys following Vaccination and Simian-Human Immunodeficiency Virus Challenge

M. Kuroda, N. Letvin, W. A. Charini, 2007, Journal of Virology.

Carbon Nanotubes Enhance CpG Uptake and Potentiate Antiglioma Immunity

Wei Liu, B. Badie, Dongchang Zhao, 2010, Clinical Cancer Research.

Intracerebral CpG Immunotherapy with Carbon Nanotubes Abrogates Growth of Subcutaneous Melanomas in Mice

B. Badie, Leying Zhang, E. Manuel, 2012, Clinical Cancer Research.