J. Ogbechi

发表

TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells

M. Feldmann, S. Luo, Richard O. Williams, 2019, Proceedings of the National Academy of Sciences.

IDO and Kynurenine Metabolites in Peripheral and CNS Disorders

Richard O. Williams, T. Stone, F. Clanchy, 2020, Frontiers in Immunology.

Mycolactone enhances the Ca leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca permeable state

A. Cavalié, V. Helms, B. Hall, 2021 .

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, bioRxiv.

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

J. Taunton, B. Hall, R. Wek, 2018, Cell Death & Disease.

Inhibition of Sec 61-dependent translocation by mycolactone 1 uncouples the integrated stress response from ER stress , driving 2 cytotoxicity via translational activation of ATF 4 3 4

J. Taunton, B. Hall, A. Willis, 2018 .

Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in Buruli ulcer lesions

B. Hall, G. Pluschke, L. T. Hsieh, 2022, PLoS pathogens.

Modulation of immune cell function, IDO expression and kynurenine production by the quorum sensor 2-heptyl-3-hydroxy-4-quinolone (PQS)

Richard O. Williams, T. Stone, L. Darlington, 2022, Frontiers in Immunology.

cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs

P. Venables, Richard O. Williams, J. Ogbechi, 2019, Science Advances.

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

C. Esmon, B. Hall, Hua-Lin Wu, 2015, PLoS pathogens.

IDO activation, inflammation and musculoskeletal disease

Richard O. Williams, T. Stone, F. Clanchy, 2019, Experimental Gerontology.

Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?

Richard O. Williams, T. Stone, L. Darlington, 2022, Frontiers in Immunology.

Investigating the mechanism behind the tissue necrosis in mycobacterium ulcerans infection.

J. Ogbechi, 2017 .

Pharmacological modulation of T cell immunity results in long-term remission of autoimmune arthritis

L. Salford, S. Luo, Richard O. Williams, 2021, Proceedings of the National Academy of Sciences.

The Pathogenic Mechanism of the Mycobacterium ulcerans Virulence Factor, Mycolactone, Depends on Blockade of Protein Translocation into the ER

Michael McKenna, Anne E. Willis, S. High, 2014, PLoS pathogens.

Aberrant stromal tissue factor and mycolactone-driven vascular permeability, exacerbated by IL-1Î², orchestrate pathogenic fibrin formation in Buruli ulcer lesions

G. Pluschke, L. T. Hsieh, J. Ogbechi, 2021, medRxiv.

LAT1 enables T cell activation under inflammatory conditions: a new therapeutic target for rheumatoid arthritis

H. L. Wright, A. Filer, Richard O. Williams, 2022, bioRxiv.

Inhibition of Sec61-dependent translocation by mycolactone uncouples the integrated stress response from ER stress, driving cytotoxicity via translational activation of ATF4

J. Taunton, B. Hall, R. Wek, 2018, Cell Death & Disease.

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state

A. Cavalié, V. Helms, B. Hall, 2021, Biochemical Journal.