V. Sambandamurthy

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Guest Editorial Articles Einstein Contained Aerosol Pulmonizer (ecap): Improved Biosafety for Multi-drug Resistant (mdr) and Extensively Drug Resistant (xdr) Mycobacterium Tuberculosis Aerosol Infection Studies Biosafety Onboard the International Space Station Survival of Microorganisms on Hepa Filt

C. Vilchèze, Tsungda Hsu, V. Sambandamurthy, 2012 .

Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.

S. Cole, Anirban Ghosh, M. Fellows, 2015, Bioorganic & medicinal chemistry.

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.

Christopher B. Cooper, Amit K. Gupta, D. Murray, 2017, Journal of medicinal chemistry.

Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates.

B. Haynes, Bing Chen, W. Jacobs, 2009, Vaccine.

Priming with a Recombinant Pantothenate Auxotroph of Mycobacterium bovis BCG and Boosting with MVA Elicits HIV-1 Gag Specific CD8+ T Cells

W. Jacobs, B. Ryffel, A. Williamson, 2012, PloS one.

The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease.

P. Niyomrattanakit, D. Jeffery, M. Riwanto, 2011, Angewandte Chemie.

Scaffold morphing leading to evolution of 2,4-diaminoquinolines and aminopyrazolopyrimidines as inhibitors of the ATP synthesis pathway

Amit K. Gupta, G. Balakrishnan, A. Narayan, 2016 .

Investigation into a community outbreak of Salmonella Typhi in Bengaluru, India

V. Sambandamurthy, G. Varghese, M. Reddy, 2017, The Indian journal of medical research.

A Nanowire-Based Flexible Antibacterial Surface Reduces the Viability of Drug-Resistant Nosocomial Pathogens

P. Sen, D. Chakravortty, Arvind Kumar, 2018, ACS Applied Nano Materials.

Einstein Contained Aerosol Pulmonizer (ECAP): Improved Biosafety for Multi-Drug Resistant (MDR) and Extensively Drug Resistant (XDR) Mycobacterium tuberculosis Aerosol Infection Studies

C. Vilchèze, T. Weisbrod, Bing Chen, 2011, Applied biosafety : journal of the American Biological Safety Association.

Induction of high levels of protective immunity in mice after vaccination using dendritic cells infected with auxotrophic mutants of Mycobacterium tuberculosis.

W. Jacobs, J. Chan, V. Sambandamurthy, 2006, Immunology letters.

Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis.

J. Tucker, T. Balganesh, V. Sambandamurthy, 2013, ACS chemical biology.

Left-Hand Side Exploration of Novel Bacterial Topoisomerase Inhibitors to Improve Selectivity against hERG Binding.

V. Sambandamurthy, Sreevalli Sharma, V. Shinde, 2015, ACS medicinal chemistry letters.

Benzimidazoles: novel mycobacterial gyrase inhibitors from scaffold morphing.

V. Sambandamurthy, Sreevalli Sharma, J. Reddy, 2014, ACS medicinal chemistry letters.

Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.

Bing Chen, W. Jacobs, S. Porcelli, 2006, Vaccine.

An IPTG Inducible Conditional Expression System for Mycobacteria

H. Ramu, Sudha Ramaiah, A. Anbarasu, 2015, PloS one.

Multi-scale surface topography to minimize adherence and viability of nosocomial drug-resistant bacteria

J. Hasan, K. Chatterjee, V. Sambandamurthy, 2018, Materials & design.

Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis.

T. Dick, N. Ma, T. Keller, 2008, Journal of Antimicrobial Chemotherapy.

Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis.

W. Jacobs, M. Pavelka, G. Hatfull, 2002, Microbiology.

In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis

S. Cole, N. Dhar, C. Sala, 2014, Antimicrobial Agents and Chemotherapy.

Bactericidal Activity and Mechanism of Action of AZD5847, a Novel Oxazolidinone for Treatment of Tuberculosis

S. Butler, V. Subbulakshmi, V. Ramachandran, 2013, Antimicrobial Agents and Chemotherapy.

A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis

Bing Chen, W. Jacobs, R. Russell, 2002, Nature Medicine.

Discriminatory power of three typing techniques in determining relatedness of nosocomial Klebsiella pneumoniae isolates from a tertiary hospital in India

V. Sambandamurthy, G. Varghese, M. Reddy, 2017, Indian journal of medical microbiology.

Exploring the Mode of Action of Bioactive Compounds by Microfluidic Transcriptional Profiling in Mycobacteria

Mark J. Schreiber, M. Hibberd, P. Bifani, 2013, PloS one.

Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate

D. Wirth, D. Fidock, Pavithra Viswanath, 2015, Nature Communications.

Protection Elicited by a Double Leucine and Pantothenate Auxotroph of Mycobacterium tuberculosis in Guinea Pigs

William R. Jacobs, W. Jacobs, R. Russell, 2004, Infection and Immunity.

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

C. Eyermann, G. Balakrishnan, F. Reck, 2015, Tuberculosis.

Thiazolopyridone ureas as DNA gyrase B inhibitors: optimization of antitubercular activity and efficacy.

Vijay T. Ahuja, D. Ogg, P. Boriack-Sjodin, 2014, Bioorganic & medicinal chemistry letters.

Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.

Vijay T. Ahuja, D. Ogg, J. Tucker, 2013, Journal of medicinal chemistry.

Long-Term Protection against Tuberculosis following Vaccination with a Severely Attenuated Double Lysine and Pantothenate Auxotroph of Mycobacterium tuberculosis

Bing Chen, W. Jacobs, R. Russell, 2005, Infection and Immunity.

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.

J. Mckinney, L. Chiarelli, N. Dhar, 2014, Journal of medicinal chemistry.

Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.

A. Narayan, V. Ramachandran, V. Sambandamurthy, 2014, Journal of medicinal chemistry.

Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.

Vijay T. Ahuja, A. Srivastava, A. Narayan, 2013, Journal of medicinal chemistry.

Lead optimization of 1,4-azaindoles as antimycobacterial agents.

Christopher B. Cooper, S. Butler, A. Srivastava, 2014, Journal of medicinal chemistry.

Methyl-thiazoles: a novel mode of inhibition with the potential to develop novel inhibitors targeting InhA in Mycobacterium tuberculosis.

Shahul Hameed, Geoffrey Holdgate, V. Sambandamurthy, 2013, Journal of medicinal chemistry.

Scaffold Morphing To Identify Novel DprE1 Inhibitors with Antimycobacterial Activity.

Christopher B. Cooper, S. Butler, A. Narayan, 2019, ACS medicinal chemistry letters.

for Treatment of Tuberculosis Action of AZD 5847 , a Novel Oxazolidinone Bactericidal Activity and Mechanism of

V. Sharma, S., V. Subbulakshmi, 2013 .

Nitroarenes as Antitubercular Agents: Stereoelectronic Modulation to Mitigate Mutagenicity

M. Fellows, J. Neres, V. Ramachandran, 2016, ChemMedChem.

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.

D. Fidock, F. Gamo, A. Srivastava, 2014, Journal of medicinal chemistry.

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.

D. Wirth, F. Gamo, Pavithra Viswanath, 2014, Journal of medicinal chemistry.

Synthesis and structure activity relationship of imidazo[1,2-a]pyridine-8-carboxamides as a novel antimycobacterial lead series.

K. Mukherjee, V. Ramachandran, V. Sambandamurthy, 2013, Bioorganic & medicinal chemistry letters.

Assessment of Mycobacterium tuberculosis Pantothenate Kinase Vulnerability through Target Knockdown and Mechanistically Diverse Inhibitors

Anirban Ghosh, K. Mukherjee, V. Ramachandran, 2014, Antimicrobial Agents and Chemotherapy.

Pyrazolopyrimidines establish MurC as a vulnerable target in Pseudomonas aeruginosa and Escherichia coli.

C. Eyermann, B. Paul, V. Sambandamurthy, 2014, ACS chemical biology.

Optimization of Pyrrolamides as Mycobacterial GyrB ATPase Inhibitors: Structure-Activity Relationship and In Vivo Efficacy in a Mouse Model of Tuberculosis

Anirban Ghosh, K. Mukherjee, V. Subbulakshmi, 2013, Antimicrobial Agents and Chemotherapy.

Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis

W. Jacobs, S. Hingley-Wilson, V. Sambandamurthy, 2003, Nature Immunology.

Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis.

W. Jacobs, V. Sambandamurthy, 2005, Microbes and infection.

Essentiality Assessment of Cysteinyl and Lysyl-tRNA Synthetases of Mycobacterium smegmatis

Sudha Ramaiah, A. Anbarasu, V. Sambandamurthy, 2016, PloS one.

Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.

Anirban Ghosh, K. Mukherjee, S. Hoffner, 2014, Journal of medicinal chemistry.

Characterization of the protective T‐cell response generated in CD4‐deficient mice by a live attenuated Mycobacterium tuberculosis vaccine

Bing Chen, W. Jacobs, I. Orme, 2007, Immunology.

Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis.

K. Mukherjee, V. Subbulakshmi, V. Sambandamurthy, 2010, Microbiology.

In Vitro Activity of AZD5847 against Geographically Diverse Clinical Isolates of Mycobacterium tuberculosis

C. Rodrigues, S. Hoffner, V. Balasubramanian, 2014, Antimicrobial Agents and Chemotherapy.

Insulin Tregopil: An Ultra-Fast Oral Recombinant Human Insulin Analog: Preclinical and Clinical Development in Diabetes Mellitus

S. Joshi, V. Sambandamurthy, S. Athalye, 2023, Drugs.

Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.

C. Eyermann, G. Balakrishnan, F. Reck, 2015, Tuberculosis.