Stefan Abele

发表

Development of a Scaleable Route for the Production of cis-N-Benzyl-3-methylamino-4-methylpiperidine

Glenn E Wilcox, D. Ripin, Stefan Abele, 2003 .

Continuous Process for Phase-Transfer-Catalyzed Bisalkylation of Cyclopentadiene for the Synthesis of Spiro[2.4]hepta-4,6-diene

R. Marti, Stefan Abele, E. Vanoli, 2016 .

Scalable synthesis of enantiomerically pure bicyclo[2.2.2]octadiene ligands.

Stefan Abele, C. Moessner, R. Inauen, 2012, The Journal of organic chemistry.

Scalable Synthesis of Trifluoromethylated Imidazo-Fused N-Heterocycles Using TFAA and Trifluoroacetamide as CF3-Reagents.

Stefan Abele, G. Schäfer, Muhamed Ahmetovic, 2017, Organic letters.

Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold‐Hopping Approach

M. Bolli, C. Brotschi, Stefan Abele, 2016, ChemMedChem.

BIOLOGICAL AND PHARMACOKINETIC STUDIES WITH BETA -PEPTIDES

A. Nussbaum, D. Seebach, R. Woessner, 1998 .

CD Spectra in Methanol ofβ-Oligopeptides Consisting ofβ-Amino Acids with Functionalized Side Chains, with Alternating Configuration, and with Geminal Backbone Substituents - Fingerprints of New Secondary Structures?

D. Seebach, Daniel J. Bierbaum, Stefan Abele, 2000 .

Novel S1P1 receptor agonists--part 1: From pyrazoles to thiophenes.

M. Bolli, Stefan Abele, A. Treiber, 2013, Journal of medicinal chemistry.

β‐Peptides as Inhibitors of Small‐Intestinal Cholesterol and Fat Absorption

H. Hauser, D. Seebach, Stefan Abele, 1999 .

Practical and Scalable Synthesis of S1P1 Receptor Agonist ACT-209905

S. Reber, M. Bolli, Stefan Abele, 2012 .

(S)-β3-Homolysine- and (S)-β3-Homoserine-Containingβ-Peptides: CD Spectra in Aqueous Solution

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Preparation of N-Fmoc-Protected β2- and β3-Amino Acids and their use as building blocks for the solid-phase synthesis of β-peptides†‡

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Practical Synthesis of a S1P Receptor 1 Agonist via a Guareschi–Thorpe Reaction

M. Bolli, Stefan Abele, C. Lescop, 2016 .

A One-Pot Diazotation–Fluorodediazoniation Reaction and Fluorine Gas for the Production of Fluoronaphthyridines

Stefan Abele, G. Schmidt, H. Steiner, 2014 .

Scalable and Practical Synthesis of Halo Quinolin-2(1H)-ones and Quinolines

Stefan Abele, G. Schmidt, Cornelia Zaugg, 2017 .

Design and Scale-Up of a Practical Enantioselective Route to 5-Phenylbicyclo[2.2.2]oct-5-en-2-one

Stefan Abele, T. Weller, R. Inauen, 2012 .

Diastereospecific Enolate Addition and Atom-Efficient Benzimidazole Synthesis for the Production of L/T Calcium Channel Blocker ACT-280778

Y. Guggisberg, M. Struijk, T. Seidel, 2014 .

Scalable Process for the Production of a Highly Energetic Bromoacetylene Building Block

R. Karge, Stefan Abele, A. Stutz, 2018, Organic Process Research & Development.

Catalytic Asymmetric Reduction of a 3,4-Dihydroisoquinoline for the Large-Scale Production of Almorexant: Hydrogenation or Transfer Hydrogenation?

T. Dax, Stefan Abele, R. Ward, 2013 .

One-Pot Synthesis of Trifluoromethylated Quinazolin-4(3 H)-ones with Trifluoroacetic Acid as CF3 Source.

R. Marti, Stefan Abele, E. Vanoli, 2018, The Journal of organic chemistry.

Metal-Free Amidation of Acids with Formamides and T3P®

Stefan Abele, Simone Tortoioli, L. Bannwart, 2016 .

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

M. Bolli, Stefan Abele, A. Treiber, 2010, Journal of medicinal chemistry.

Preparation of Achiral and of Enantiopure Geminally Disubstituted β‐Amino Acids for β‐Peptide Synthesis

D. Seebach, Stefan Abele, 2000 .

Industrial applications of the Diels-Alder reaction.

Stefan Abele, Jacques-Alexis Funel, 2013, Angewandte Chemie.

Development of a Scalable Route for a Highly Polar Heterocyclic Aminocyclopropyl Building Block

Stefan Abele, G. Schäfer, Muhamed Ahmetovic, 2020 .

Metal-Free Amidation of Acids with Formamides and T3P®.

Stefan Abele, Simone Tortoioli, L. Bannwart, 2016 .

Preparation and Structure ofβ-Peptides Consisting of Geminally Disubstitutedβ2,2- andβ3,3-Amino Acids: A Turn Motif forβ-Peptides

D. Seebach, M. Hänggi, Stefan Abele, 1998 .

β2‐ and β3‐Peptides with Proteinaceous Side Chains: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding

B. Jaun, D. Seebach, K. Gademann, 1998 .

Pleated Sheets and Turns of β-Peptides with Proteinogenic Side Chains.

B. Jaun, D. Seebach, K. Gademann, 1999, Angewandte Chemie.

High-Temperature Diels–Alder Reactions: Transfer from Batch to Continuous Mode

Roger Marti, Stefan Höck, Gunther Schmidt, 2012 .

Structure and Conformation ofβ-Oligopeptide Derivatives with Simple Proteinogenic Side Chains: Circular Dichroism and Molecular Dynamics Investigations

X. Daura, W. F. Gunsteren, D. Seebach, 2000 .

Synthesis, Crystal Structures, and Modelling ofβ-Oligopeptides Consisting of 1-(Aminomethyl)cyclopropanecarboxylic Acid: Ribbon-Type Arrangement of Eight-Membered H-Bonded Rings

D. Seebach, Stefan Abele, P. Seiler, 1999 .

Preparation and Structure of β‐Peptides Consisting of Geminally Disubstituted β2,2‐ and β3,3‐Amino Acids: A Turn Motif for β‐Peptides.

M. Haenggi, D. Seebach, Stefan Abele, 1999 .

Safety Assessment for the Scale-up of an Oxime Reduction with Melted Sodium in Standard Pilot-Plant Equipment

Stefan Abele, T. Fink, R. A. Breitenmoser, 2012 .

Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.

R. de Kanter, M. Bolli, Stefan Abele, 2014, Journal of medicinal chemistry.

Design and Scale-Up of Diels–Alder Reactions for the Practical Synthesis of 5-Phenylbicyclo[2.2.2]oct-5-en-2-one

Stefan Abele, G. Schmidt, Jacques-Alexis Funel, 2011 .

Thermal Risk Assessment: A Powerful Tool for Route Selection for Scale-Up Applied to Diels–Alder Reactions

Stefan Abele, G. Schmidt, M. Schwaninger, 2014 .

C1‐Symmetric Bicyclo[2.2.2]octa‐2,5‐diene (bod*) Ligands in Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Arylboronic Acids to Enones and 1,2‐Addition to N‐[(4‐Nitrophenyl)sulfonyl]imines

R. Marti, Stefan Abele, R. Brönnimann, 2012 .

Safety Assessment of Diels–Alder Reactions with Highly Reactive Acrylic Monomers

F. Stoessel, Stefan Abele, G. Schmidt, 2012 .

C1‐Symmetric Bicyclo[2.2.2]octa‐2,5‐diene (Bod*) Ligands in Rhodium‐Catalyzed Asymmetric 1,4‐Addition of Arylboronic Acids to Enones and 1,2‐Addition to N‐[(4‐Nitrophenyl)sulfonyl]imines.

R. Marti, Stefan Abele, Sothys Chun, 2013 .

Development of a Scalable Route for a Key Thiadiazole Building Block via Sequential Sandmeyer Bromination and Room-Temperature Suzuki–Miyaura Coupling

Stefan Abele, G. Schäfer, Muhamed Ahmetovic, 2020 .

A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.

Stefan Abele, E. Corley, A. Roy, 2011, The Journal of organic chemistry.

Enantiospecific cyclization of methyl N-(tert-butoxycarbonyl)-N-(3-chloropropyl)-D-alaninate to 2-methylproline derivative via ‘memory of chirality’ in flow

Stefan Abele, S. Richard-Bildstein, G. Schmidt, 2018, Journal of Flow Chemistry.

Oligomers ofβ2- and ofβ3-Homoproline: What are the Secondary Structures ofβ-Peptides Lacking H-Bonds?

D. Seebach, Stefan Abele, Kurt Vögtli, 1999 .

Preparation of N-Fmoc-Protected β2- and β3-Amino Acids and Their Use as Building Blocks for the Solid-Phase Synthesis of β-Peptides.

D. Seebach, G. Guichard, Stefan Abele, 1998 .

Short Synthesis of a Proline Amide Orexin Receptor Antagonist on the Pilot Plant Scale

T. Pabst, D. Marchal, Stefan Abele, 2014 .

2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

M. Bolli, Stefan Abele, A. Treiber, 2010, Journal of medicinal chemistry.

Industrial applications of the Diels-Alder reaction.

Stefan Abele, Jacques-Alexis Funel, 2013, Angewandte Chemie.

Structure and Conformation of β‐Oligopeptide Derivatives with Simple Proteinogenic Side Chains: Circular Dichroism and Molecular Dynamics Investigations.

X. Daura, W. F. Gunsteren, D. Seebach, 2000 .