D. Whipple

发表

Development of a Scaleable Route for the Production of cis-N-Benzyl-3-methylamino-4-methylpiperidine

Glenn E Wilcox, D. Ripin, Stefan Abele, 2003 .

Prevention of Organ Allograft Rejection by a Specific Janus Kinase 3 Inhibitor

J. O’Shea, A. Milici, B. Reitz, 2003, Science.

Immobilized peptide arrays: A new technology for the characterization of protease function

B. Morgan, D. Whipple, T. Siahaan, 1994 .

Aspartyl alpha-((diphenylphosphinyl)oxy)methyl ketones as novel inhibitors of interleukin-1 beta converting enzyme. Utility of the diphenylphosphinic acid leaving group for the inhibition of cysteine proteases.

T. Graybill, R. Dolle, D. Whipple, 1995, Journal of medicinal chemistry.

Preparation, gram-negative antibacterial activity, and hydrolytic stability of novel siderophore-conjugated monocarbam diols.

T. Gootz, M. Huband, S. J. Brickner, 2011, ACS medicinal chemistry letters.

Discovery of azetidinyl ketolides for the treatment of susceptible and multidrug resistant community-acquired respiratory tract infections.

Bryan M. Li, T. Dougherty, R. Obach, 2009, Journal of medicinal chemistry.

Identification of Potent and Selective Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase (PfM18AAP) of Human Malaria via High-Throughput Screening

J. Dalton, T. Spicer, P. Ghosh, 2014, Journal of biomolecular screening.

The specificity of JAK3 kinase inhibitors.

M. Munchhof, T. Harris, P. Changelian, 2008, Blood.

Potency enhancement of the κ-opioid receptor antagonist probe ML140 through sulfonamide constraint utilizing a tetrahydroisoquinoline motif.

L. Bohn, Lei Zhou, K. Lovell, 2015, Bioorganic & medicinal chemistry.

Cyclic homopentapeptides 1. Analogs of tuberactinomycins and capreomycin with activity against vancomycin-resistant enterococci and Pasteurella

S. Miller, J. Lyssikatos, M. Lemay, 1997 .

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy.

M. Caron, T. Chung, M. Hedrick, 2012, ACS chemical neuroscience.

Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection.

M. Hines, M. Munchhof, P. Changelian, 2010, Journal of medicinal chemistry.

Relationship between structure and bioavailability in a series of hydroxamate based metalloprotease inhibitors

R. Wahl, B. Morgan, D. Whipple, 1995 .

Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.

T. Chung, E. Sergienko, B. Blagg, 2015, ACS combinatorial science.

Application of Genetic Algorithms to Combinatorial Synthesis: A Computational Approach to Lead Identification and Lead Optimization†,∇

Edward P. Jaeger, Adi M. Treasurywala, Jasbir Singh, 1996 .

Cyclic homopentapeptides 3. Synthetic modifications to the capreomycins and tuberactinomycins: Compounds with activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci

J. Lyssikatos, D. Whipple, R. Chandrasekaran, 1997 .

Cyclic Homopentapeptides. Part 3. Synthetic Modifications to the Capreomycins and Tuberactinomycins: Compounds with Activity Against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci.

J. Lyssikatos, D. Whipple, R. Chandrasekaran, 1997 .

Validation of screening immobilized peptide libraries for discovery of protease substrates.

A. Treasurywala, B. Morgan, J. Solowiej, 1995, Journal of Medicinal Chemistry.

Inhibitors of the Plasmodium falciparum M18 Aspartyl Aminopeptidase

Nichole A. Tower, J. Dalton, T. Spicer, 2014 .