J. Vaage

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Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms

E. Ignatieva, A. Malashicheva, A. Kostareva, 2016, International journal of vascular medicine.

Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells

G. Sullivan, A. Malashicheva, A. Kostareva, 2018, Front. Physiol..

Mitochondrial DNA damage and repair during ischemia-reperfusion injury of the heart.

M. Bjørås, R. Suganthan, M. Bliksøen, 2015, Journal of molecular and cellular cardiology.

Serglycin in Quiescent and Proliferating Primary Endothelial Cells

T. Jenssen, S. O. Kolset, J. Vaage, 2015, PloS one.

Induction of inflammatory mediators during reperfusion of the human heart.

G. Valen, J. Vaage, G. Paulsson, 2001, The Annals of thoracic surgery.

Life without Oxygen: Gene Regulatory Responses of the Crucian Carp (Carassius carassius) Heart Subjected to Chronic Anoxia

Yongxiang Fang, A. Farrell, G. Nilsson, 2014, PloS one.

Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius).

G. Nilsson, S. Ellefsen, J. Vaage, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

ISOFLURANE AND OTHER COMMONLY USED ANAESTHETICS DO NOT PROTECT THE ISOLATED BUFFER PERFUSED MOUSE HEART FROM ISCHEMIA‐REPERFUSION INJURY

G. Valen, J. Vaage, M. Galagudza, 2006, Clinical and experimental pharmacology & physiology.

Intraperitoneal injection induces a delayed preconditioning-like effect in mice

G. Valen, J. Vaage, F. Labruto, 2005, Laboratory animals.

Pre– and postconditioning during cardiac surgery

G. Valen, J. Vaage, 2005, Basic Research in Cardiology.

Ischemic postconditioning: brief ischemia during reperfusion converts persistent ventricular fibrillation into regular rhythm.

G. Valen, J. Vaage, M. Galagudza, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Role of tumor necrosis factor alpha and its receptor I in preconditioning by hyperoxia

G. Valen, J. Vaage, F. Labruto, 2005, Basic Research in Cardiology.

Preconditioning and cardiac surgery.

G. Valen, J. Vaage, 2003, The Annals of thoracic surgery.

Adaptation to Ischemia by in vivo Exposure to Hyperoxia—Signalling through Mitogen Activated Protein Kinases and Nuclear Factor Kappa B

J. Starkopf, G. Valen, J. Vaage, 2003 .

Cardioprotection by breathing hyperoxic gas-relation to oxygen concentration and exposure time in rats and mice.

J. Starkopf, G. Valen, J. Vaage, 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Preconditioning with hydrogen peroxide (H2O2) or ischemia in H2O2-induced cardiac dysfunction.

J. Starkopf, G. Valen, J. Vaage, 1998, Free radical research.

Preconditioning the globally ischaemic, isolated rat heart: the impact of the preconditioning model on post-ischaemic systolic and diastolic function.

G. Valen, J. Vaage, S. Takeshima, 1997, Scandinavian journal of clinical and laboratory investigation.

Preconditioning improves cardiac function after global ischemia, but not after cold cardioplegia.

G. Valen, J. Vaage, S. Takeshima, 1996, The Annals of thoracic surgery.

Extracellular mtDNA activates NF-κB via toll-like receptor 9 and induces cell death in cardiomyocytes

I. Seljeflot, M. Bliksøen, G. Valen, 2016, Basic Research in Cardiology.

The cardiothoracic surgeon and the basic scientist.

J. Vaage, Jarle Vaage, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Cardiovascular function during the first 24 hours after off pump coronary artery bypass grafting--a prospective, randomized study.

J. Vaage, A. Ericsson, J. Vedin, 2003, Interactive cardiovascular and thoracic surgery.

Activation of complement and leukocyte receptors during on- and off pump coronary artery bypass surgery.

J. Lundahl, J. Vaage, L. Wehlin, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Toxic oxygen metabolites and leukocytes in reperfusion injury. A review.

G. Valen, J. Vaage, 1993, Scandinavian journal of thoracic and cardiovascular surgery. Supplementum.

Oxygen free radical producing leukocytes cause functional depression of isolated rat hearts: role of leukotrienes.

A. Semb, J. Vaage, O. Mjøs, 1990, Journal of molecular and cellular cardiology.

Endothelial injury and trapping of blood cells in human myocardium following coronary bypass surgery.

J. Vaage, S. Lindal, L. Jørgensen, 1999, Scandinavian cardiovascular journal : SCJ.

Pathophysiology and mediators of ischemia-reperfusion injury with special reference to cardiac surgery. A review.

G. Valen, J. Vaage, 1993, Scandinavian journal of thoracic and cardiovascular surgery. Supplementum.

Could treatment with scavengers of oxygen free radicals minimize complications in cardiac surgery?

J. Vaage, G. Valen, 1991, Klinische Wochenschrift.

Cardiac surgery and distribution of the leukocyte L1 protein-calprotectin.

A. Semb, T. Halstensen, P. Brandtzaeg, 1991, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Leucocytes and cardiopulmonary bypass: in vitro production of oxygen free radicals and trapping in the reperfused myocardium

A. Semb, J. Vaage, AG Semb, 1990 .

EFFECTS OF A NOVEL INHIBITOR OF LIPID PEROXIDATION ON INJURY CAUSED BY OXIDATIVE STRESS AND ISCHEMIA-REPERFUSION

J. Vaage, 2016 .

The effect of a low molecular weight inhibitor of lipid peroxidation on ultrastructural alterations to ischemia-reperfusion in the isolated rat heart.

G. Valen, R. Myklebust, J. Vaage, 2001, Acta physiologica Hungarica.

Mechanical conversion of post-ischaemic ventricular fibrillation: effects on function and myocyte injury in isolated rat hearts.

G. Valen, J. Vaage, C. Löwbeer, 1999, Scandinavian journal of clinical and laboratory investigation.

Human adaptation to ischemia by preconditioning or unstable angina: involvement of nuclear factor kappa B, but not hypoxia-inducible factor 1 alpha in the heart.

G. Czibik, G. Valen, J. Vaage, 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex

C. Drevon, A. Kimmel, F. Norheim, 2021, Journal of lipid research.

Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart.

S. Nygård, L. Gullestad, G. Czibik, 2014, Life sciences.

Per-unit-living tissue normalization of real-time RT-PCR data in ischemic rat hearts.

S. Ellefsen, M. Kaljusto, I. B. Johansen, 2012, Physiological genomics.

The p66ShcA adaptor protein regulates healing after myocardial infarction

M. Mongillo, M. Giorgio, T. Zaglia, 2015, Basic Research in Cardiology.

Exposure of rats to hyperoxia enhances relaxation of isolated aortic rings and reduces infarct size of isolated hearts.

J. Starkopf, J. Kals, G. Valen, 2002, Acta physiologica Scandinavica.

Extracorporeal membrane oxygenation (ECMO) as lung or heart assist

J. Vaage, R. Hotvedt, J. Thoner, 1996, Acta anaesthesiologica Scandinavica.

Computed tomography of the sternum and mediastinum after median sternotomy.

K. Cederlund, J. Vaage, B. Åberg, 1999, The Annals of thoracic surgery.

Oxidative stress and release of tissue plasminogen activator in isolated rat hearts.

B. Wiman, G. Valen, J. Vaage, 1997, Thrombosis research.

Release of tissue plasminogen activator during reperfusion after different times of ischaemia in isolated, perfused rat hearts.

B. Wiman, G. Valen, J. Vaage, 1996, Thrombosis research.

Neurologic injury in cardiac surgery: aortic atherosclerosis emerges as the single most important risk factor.

J. Vaage, A. Ericsson, U. Jensen, 2000, Scandinavian cardiovascular journal : SCJ.

Models and Techniques to Study Aortic Valve Calcification in Vitro, ex Vivo and in Vivo. An Overview

G. Sullivan, A. Malashicheva, A. Kostareva, 2022, Frontiers in Pharmacology.

Myocardial protection by remote preconditioning: the role of nuclear factor kappa-B p105 and inducible nitric oxide synthase.

A. Sirsjö, G. Valen, J. Vaage, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Interstitial cells in calcified aortic valves have reduced differentiation potential and stem cell-like properties

G. Sullivan, A. Malashicheva, A. Kostareva, 2019, Scientific Reports.

Release of bioactive interleukin 6 but not of tumour necrosis factor-α after elective cardiopulmonary bypass

T. Ivert, A. Waage, J. Vaage, 1993 .

Preoperative unstable angina causes venous adaptation to surgical graft injury

G. Valen, K. Hinokiyama, J. Vaage, 2007, Basic Research in Cardiology.

Release of markers of myocardial and endothelial injury following cold cardioplegic arrest in pigs.

A. Owall, B. Risberg, E. Eriksson, 1997, Scandinavian cardiovascular journal : SCJ.

Effects of a novel low-molecular weight antioxidant on cardiac injury induced by hydrogen peroxide.

G. Valen, J. Vaage, A. Nagy, 1996, Free radical biology & medicine.

Systemic release of thrombomodulin, but not from the cardioplegic, reperfused heart during open heart surgery.

O. Sigurdardottir, G. Valen, J. Vaage, 1996, Thrombosis research.

Inhibition of lipoxygenase and cyclooxygenase augments cardiac injury by H2O2.

A. Semb, G. Valen, J. Vaage, 1993, Free radical biology & medicine.

Functional impairment in isolated rat hearts induced by activated leukocytes: protective effect of oxygen free radical scavengers.

A. Semb, R. Myklebust, J. Vaage, 1989, Journal of molecular and cellular cardiology.

Hyperoxia elicits myocardial protection through a nuclear factor kappaB-dependent mechanism in the rat heart.

J. Starkopf, G. Valen, J. Vaage, 2003, The Journal of thoracic and cardiovascular surgery.

Preconditioning protects the severely atherosclerotic mouse heart.

S. Tokuno, G. Valen, J. Vaage, 2001, The Annals of thoracic surgery.

Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1.

G. Hansson, G. Valen, J. Vaage, 2000, Cardiovascular research.

The role of neuronal nitric oxide synthase in ischaemia-reperfusion injury of the isolated mouse heart.

G. Valen, J. Vaage, X. Song, 2001, Acta physiologica Scandinavica.

Proteasomal proteolysis in anoxia-reoxygenation, preconditioning and postconditioning of isolated cardiomyocytes.

J. Vaage, V. Dosenko, V. Nagibin, 2006, Pathophysiology : the official journal of the International Society for Pathophysiology.

Increase in serum S100A1-B and S100BB during cardiac surgery arises from extracerebral sources.

R. Anderson, L. Hansson, J. Liska, 2001, The Annals of thoracic surgery.

Perfusing isolated rat hearts with hydrogen peroxide: an experimental model of cardiac dysfunction caused by reactive oxygen species.

G. Valen, J. Vaage, T. Skjelbakken, 1996, Scandinavian journal of clinical and laboratory investigation.

Activities of mitochondrial aspartate aminotransferase and creatine kinase isoenzyme MB in serum following coronary bypass surgery.

J. Vaage, S. Almdahl, N. Huseby, 1990, Clinica chimica acta; international journal of clinical chemistry.

Complement activation is associated with poor outcome after out-of-hospital cardiac arrest.

K. Sunde, C. Lundqvist, G. Andersen, 2021, Resuscitation.

Thromboplastin activities and monocytes in the coronary circulation of reperfused human myocardium. No effect of preoperative treatment with n-3 fatty acids.

D. Nilsen, B. Osterud, J. Vaage, 1993, Scandinavian journal of thoracic and cardiovascular surgery.

Hyperoxia during early reperfusion does not increase ischemia/reperfusion injury.

J. Vaage, K. Stensløkken, A. Rutkovskiy, 2011, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Proteasome inhibitors eliminate protective effect of postconditioning in cultured neonatal cardiomyocytes.

J. Vaage, V. Dosenko, V. Nagibin, 2006, Fiziolohichnyi zhurnal.

A Novel Ex Vivo Model of Aortic Valve Calcification. A Preliminary Report

J. Vaage, A. Zabirnyk, K. Stensløkken, 2020, Frontiers in Pharmacology.

Original articleCardiovascular: Invited commentaryINVITED COMMENTARY

J. Vaage, 2005 .

Effects of sex, gonadectomy, and oestrogen substitution on ischaemic preconditioning and ischaemia-reperfusion injury in mice.

G. Valen, J. Vaage, G. Li, 2003, Acta physiologica Scandinavica.

Increased microvascular permeability caused by toxic oxygen metabolites is partly reversed by exchanging the perfusate in isolated rat lungs

J. Vaage, L. Bjertnæs, J. Kjæve, 1989, Acta anaesthesiologica Scandinavica.

Fibrinolysis during cardiac surgery. Release of tissue plasminogen activator in arterial and coronary sinus blood.

B. Risberg, E. Eriksson, G. Valen, 1994, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Gene expression of inflammatory mediators in different chambers of the human heart.

G. Hansson, G. Valen, J. Vaage, 2000, The Annals of thoracic surgery.

Vagal reflexes in the bronchoconstriction occurring after induced intravascular platelet aggregation.

J. Vaage, 1976, Acta physiologica Scandinavica.

Warm or cold continuous blood cardioplegia provides similar myocardial protection.

J. Vaage, S. Takeshima, A. Ericsson, 1999, The Annals of thoracic surgery.

Cardiac release of histamine after ventricular fibrillation and defibrillation during insertion of implantable cardioverter defibrillators (ICD)

M. Rosenqvist, J. Kaszaki, L. Bergfeldt, 1995, Inflammation Research.

Open heart surgery increases the levels of histamine in arterial and coronary sinus blood

J. Kaszaki, G. Valen, J. Vaage, 1994, Agents and Actions.

The effects of exogenous histamine in isolated rat hearts

G. Valen, J. Vaage, T. Skjelbakken, 1995, Molecular and Cellular Biochemistry.

Connective tissue growth factor and bone morphogenetic protein 2 are induced following myocardial ischemia in mice and humans

L. Gullestad, G. Czibik, C. Dahl, 2017, Scandinavian journal of clinical and laboratory investigation.

Vein graft harvesting induces inflammation and impairs vessel reactivity.

S. Tokuno, G. Valen, K. Hinokiyama, 2006, The Annals of thoracic surgery.

INTRAVASCULAR PLATELET AGGREGATION AND PULMONARY INJURY

J. Vaage, 1982, Annals of the New York Academy of Sciences.

Aggregation fo blood platelets and increased hydraulic conductivity of pulmonary exchange vessels.

J. Vaage, G. Nicolaysen, B. Waaler, 1976, Acta physiologica Scandinavica.

Plumonary responses to intravascular platelet aggregation in the cat.

J. Vaage, J. Hognestad, G. Bø, 1974, Acta physiologica Scandinavica.

Changes in pulmonary vascular volumes after induced intravascular aggregation of blood platelets.

J. Vaage, P. Aarseth, J. Hognestad, 1974, Acta physiologica Scandinavica.

The role of blood platelets in pulmonary responses to microembolization with barium sulphate.

J. Vaage, J. Hognestad, G. Bø, 1974, Acta physiologica Scandinavica.

The release of prostaglandin-like substances during platelet aggregation and pulmonary microembolism.

J. Vaage, P. Piper, 1975, Acta physiologica Scandinavica.

Small skin burn injury reduces cardiac tolerance to ischemia via a tumor necrosis factor alpha-dependent pathway.

G. Valen, J. Vaage, J. Pernow, 2007, Burns : journal of the International Society for Burn Injuries.

SNF472, a novel anti-crystallization agent, inhibits induced calcification in an in vitro model of human aortic valve calcification.

M. Kaljusto, J. Kvitting, J. Vaage, 2019, Vascular pharmacology.

Aquaporin-4 in the heart: expression, regulation and functional role in ischemia

M. Perreault, O. Ottersen, B. Škrbić, 2012, Basic Research in Cardiology.

Interleukin-17 (IL-17) Expression Is Reduced during Acute Myocardial Infarction: Role on Chemokine Receptor Expression in Monocytes and Their in Vitro Chemotaxis towards Chemokines

A. Maghazachi, G. Valen, J. Vaage, 2012, Toxins.

Post-ischaemic dysfunction does not correlate with release of cardiac troponin T in isolated rat hearts.

G. Valen, J. Vaage, C. Löwbeer, 1999, Acta physiologica Scandinavica.

Postoperative mediastinitis in cardiac surgery - microbiology and pathogenesis.

J. Vaage, B. Gårdlund, C. Bitkover, 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Methylprednisolone attenuates airway and vascular responses induced by reactive oxygen species in isolated, plasma-perfused rat lungs.

J. Vaage, L. Naess, L. Bjertnaes, 1996, Free radical research.

Hydrostatic pulmonary oedema is not a stimulus for prostaglandin synthesis in isolated, perfused lungs [proceedings].

J. Vaage, A. Ungar, E. Scott, 1977, British journal of pharmacology.

LACK OF RELEASE OF PROSTAGLANDINS FROM ISOLATED PER‐FUSED LUNGS DURING PULMONARY HYPERTENSION AND OEDEMA

J. Vaage, E. Scott, T. Wiberg, 1979, British journal of pharmacology.

Lung responses and platelet release reaction following induced intravascular platelet aggregation in the cat.

K. Gjesdal, J. Vaage, 1976, Scandinavian journal of clinical and laboratory investigation.

Release of Mitochondrial and Nuclear DNA During On-Pump Heart Surgery: Kinetics and Relation to Extracellular Vesicles

A. Kostareva, G. Valen, J. Vaage, 2018, Journal of Cardiovascular Translational Research.

Old skills in a new context. But do we want to use it?

J. Vaage, 2005, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Biochemical markers of neurologic injury in cardiac surgery: the rise and fall of S100beta.

J. Vaage, R. Anderson, 2001, The Journal of thoracic and cardiovascular surgery.

The effect of cardiotomy suction on the brain injury marker S100beta after cardiopulmonary bypass.

R. Anderson, L. Hansson, J. Liska, 2000, The Annals of thoracic surgery.

Deletion of the aquaporin-4 gene alters expression and phosphorylation of protective kinases in the mouse heart

J. Vaage, A. Rutkovskiy, L. Mariero, 2014, Scandinavian journal of clinical and laboratory investigation.

Postconditioning in mouse hearts is inhibited by blocking the reverse mode of the sodium-calcium exchanger.

M. Kaljusto, J. Vaage, K. Stensløkken, 2010, Interactive cardiovascular and thoracic surgery.

Effects of hydrogen sulphide on ischaemia-reperfusion injury and ischaemic preconditioning in the isolated, perfused rat heart.

M. Kaljusto, M. Bliksøen, J. Vaage, 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Preconditioning effects of steroids and hyperoxia on cardiac ischemia-reperfusion injury and vascular reactivity.

M. Kaljusto, G. Valen, J. Vaage, 2008, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Mechanical stress alters the expression of calcification-related genes in vascular interstitial and endothelial cells.

E. Ignatieva, A. Malashicheva, G. Valen, 2019, Interactive cardiovascular and thoracic surgery.

Endothelin release at reperfusion of the porcine ischaemic heart in relation to noradrenaline and neuropeptide Y.

A. Franco‐Cereceda, G. Valen, J. Vaage, 1994, Acta physiologica Scandinavica.

Postconditioning prevents apoptotic necrotic and autophagic cardiomyocyte cell death in culture.

J. Vaage, V. Nagibin, A. Moibenko, 2005, Fiziolohichnyi zhurnal.

Release of creatine kinase, troponin-T, and tissue plasminogen activator in arterial and coronary venous blood during coronary artery bypass surgery.

A. Owall, B. Risberg, E. Eriksson, 1997, Scandinavian journal of clinical and laboratory investigation.

Surgical handling of saphenous vein grafts induces expression of matrix metalloproteinase 9

P. Eriksson, G. Valen, J. Vaage, 2008, Scandinavian cardiovascular journal : SCJ.

A model of neointima formation in the atherosclerotic carotid artery of mice.

G. Valen, J. Vaage, A. Ruusalepp, 2003, Interactive cardiovascular and thoracic surgery.

Work in progress report - Experimental A model of neointima formation in the atherosclerotic carotid artery of mice q

G. Valen, J. Vaage, A. Ruusalepp, 2003 .

Release of prostaglandin-like substances during elevations of left atrial pressure in the cat.

J. Vaage, E. Scott, T. Wiberg, 1979, Acta physiologica Scandinavica.

Coronary trapping of a complement activation product (C3a des-Arg) during myocardial reperfusion in open-heart surgery.

A. Semb, J. Vaage, D. Sørlie, 1990, Scandinavian journal of thoracic and cardiovascular surgery.

Ischaemia-reperfusion and toxic oxygen metabolites do not induce release of immunoreactive atrial natriuretic factor from isolated rat hearts.

J. Sundsfjord, G. Valen, J. Vaage, 1993, Scandinavian journal of clinical and laboratory investigation.

Better preserved pulmonary endothelium-dependent vasodilation with off-pump coronary surgery.

J. Vaage, G. Settergren, M. Angdin, 2001, Scandinavian cardiovascular journal : SCJ.

Peripheral blood monocyte activation during coronary artery bypass grafting with or without cardiopulmonary bypass

J. Lundahl, J. Vaage, L. Wehlin, 2005, Scandinavian cardiovascular journal : SCJ.

In vivo visualization and ex vivo quantification of experimental myocardial infarction by indocyanine green fluorescence imaging.

E. Pochkaeva, J. Vaage, S. Chefu, 2017, Biomedical optics express.

Pretreating rats with hyperoxia attenuates ischemia-reperfusion injury of the heart.

J. Starkopf, G. Valen, J. Vaage, 2001, Life sciences.

Release of prostaglandin-like substances and lung reactions to induced intravascular platelet aggregation in cats.

J. Vaage, E. Scott, T. Wiberg, 1978, Scandinavian journal of clinical and laboratory investigation.

Prostaglandin content in blood and lung tissue during alveolar hypoxia.

K. Gautvik, J. Vaage, A. Hauge, 1978, Acta physiologica Scandinavica.

Importance of preanalytical handling of samples for measurement of cardiac troponin T in coronary effluent from isolated rat hearts

G. Valen, J. Vaage, C. Löwbeer, 2002, Scandinavian journal of clinical and laboratory investigation.

The pulmonary vasoconstrictor response to hypoxia: effects of inhibitors of prostaglandin biosynthesis.

J. Vaage, L. Bjertnæs, A. Hauge, 1975, Acta physiologica Scandinavica.

Release of histamine from isolated rat hearts during reperfusion is not dependent on length of ischemic insult, or contents of histamine in cardiac tissue

J. Kaszaki, G. Valen, J. Vaage, 1993, Agents and Actions.

Simultaneous antegrade and retrograde delivery of continuous warm blood cardioplegia after global ischemia.

J. Vaage, S. Takeshima, A. Ericsson, 1998, The Journal of thoracic and cardiovascular surgery.

Pretreatment with methylprednisolone protects the isolated rat heart against ischaemic and oxidative damage

J. Starkopf, G. Valen, J. Vaage, 2000, Free radical research.

Oxygen free radical-induced injury in isolated rat hearts: effects of ibuprofen and BW 755c.

A. Semb, J. Vaage, 1991, Scandinavian journal of clinical and laboratory investigation.

Congenital abdominal aortic aneurysm in a young adult. Case report.

T. Myrmel, J. Vaage, 1991, The European journal of surgery = Acta chirurgica.

Influence of a Concentrated Ethylester Compound of n-3 Fatty Acids on Lipids, Platelets and Coagulation in Patients Undergoing Coronary Bypass Surgery

D. Nilsen, K. Rasmussen, B. Osterud, 1991, Thrombosis and Haemostasis.

Hemostasis in off-pump compared to on-pump coronary artery bypass grafting: a prospective, randomized study.

J. Vaage, A. Antovic, A. Ericsson, 2005, The Annals of thoracic surgery.

Determination of components of the plasma proteolytic enzyme systems gives information of prognostic value in patients with multiple trauma.

A. Aasen, P. Kierulf, J. Vaage, 1983, Advances in experimental medicine and biology.

Release of von Willebrand factor by cardiopulmonary bypass, but not by cardioplegia in open heart surgery.

M. Blombäck, G. Valen, J. Vaage, 1994, Thrombosis research.

Chromogenic peptide substrate assays in patients with multiple trauma.

A. Aasen, P. Kierulf, J. Vaage, 1982, Acta chirurgica Scandinavica. Supplementum.

Granulocyte and eicosanoid gradients across the coronary circulation during myocardial reperfusion in cardiac surgery.

A. Semb, J. Vaage, K. Forsdahl, 1990, European Journal of Cardio-Thoracic Surgery.

Increased extracellular brain water after coronary artery bypass grafting is avoided by off-pump surgery.

R. Anderson, T. Li, J. Vaage, 1999, Journal of cardiothoracic and vascular anesthesia.

Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery.

A. Holmgren, G. Valen, J. Vaage, 1998, Free radical biology & medicine.

Cardiac aquaporins

G. Valen, J. Vaage, A. Rutkovskiy, 2013, Basic Research in Cardiology.

A dose–response study of glutamate supplementation in isolated, perfused rat hearts undergoing ischaemia and cold cardioplegia

H. Bøtker, G. Valen, J. Vaage, 2018, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Glucocorticoid pretreatment protects cardiac function and induces cardiac heat shock protein 72.

G. Valen, J. Vaage, C. Löwbeer, 2000, American journal of physiology. Heart and circulatory physiology.

Transient hyperosmolality modulates expression of cardiac aquaporins.

S. Nygård, G. Valen, J. Vaage, 2012, Biochemical and biophysical research communications.

Expression of heat shock proteins in anoxic crucian carp (Carassius carassius): support for cold as a preparatory cue for anoxia.

G. Nilsson, S. Ellefsen, J. Vaage, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

Oxygen- and temperature-dependent expression of survival protein kinases in crucian carp (Carassius carassius) heart and brain.

G. Nilsson, J. Vaage, K. Stensløkken, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

Histamine release and its effects in ischaemia-reperfusion injury of the isolated rat heart.

J. Kaszaki, G. Valen, J. Vaage, 1994, Acta physiologica Scandinavica.

Biochemical markers of cerebrospinal ischemia after repair of aneurysms of the descending and thoracoabdominal aorta.

L. Hansson, L. Rosengren, J. Vaage, 2003, Journal of cardiothoracic and vascular anesthesia.

Reactive oxygen intermediates and ischemia-reperfusion injury release tissue plasminogen activator from isolated rat hearts.

B. Risberg, E. Eriksson, G. Valen, 1993, Thrombosis research.

Ventilation by external high-frequency oscillations improves cardiac function after coronary artery bypass grafting.

J. Vaage, B. Sidenö, 1997, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Pulmonary Aspiration of Acid: An Experimental Study on Cats

J. Vaage, A. Hauge, 1974, Acta anaesthesiologica Scandinavica. Supplementum.

The effect of exogenous adenosine on functional injury caused by hydrogen peroxide in the isolated rat heart.

G. Valen, J. Vaage, 1996, Free radical research.

Toxic oxygen metabolites and ischemia-reperfusion increase histamine synthesis and release in the isolated rat heart.

J. Kaszaki, G. Valen, J. Vaage, 1993, Journal of molecular and cellular cardiology.

Small airway constriction and closure after induced intravascular platelet aggregation.

J. Vaage, A. Hauge, 1977, Acta physiologica Scandinavica.

High-dose corticosteroids in thoracic trauma.

J. Svennevig, J. Pillgram-Larsen, J. Vaage, 1985, Acta chirurgica Scandinavica. Supplementum.

Formed Elements of the Blood Platelets, and Thrombosis

F. Mckenzie, M. Debakey, D. Stasiw, 1976 .

Corticosteroids in the treatment of blunt injury of the chest.

J. Svennevig, J. Vaage, O. Geiran, 1984, Injury.

Methylprednisolone Reduces Vascular Resistance in Hypoxic and Atelectatic Lungs

J. Vaage, L. Bjertnæs, L. STRØMME‐HANSEN, 1985, Acta anaesthesiologica Scandinavica.

Methylprednisolone attenuates hypoxic pulmonary vasoconstriction in man

J. Vaage, L. Bjertnaes, 1996, Intensive Care Medicine.

Release of S100B during coronary artery bypass grafting is reduced by off-pump surgery.

R. Anderson, L. Hansson, J. Vaage, 1999, The Annals of thoracic surgery.

Late sequelae of lung contusion.

H. Refsum, J. Svennevig, J. Vaage, 1989, Injury.

Effects of a novel, low-molecular weight inhibitor of lipid peroxidation on ischemia-reperfusion injury in isolated rat hearts and in cultured cardiomyocytes.

G. Valen, J. Vaage, P. Sjöquist, 1998, Free radical biology & medicine.

Lipid peroxidation in open-heart surgery

H. Esterbauer, G. Valen, J. Vaage, 1994, Perfusion.

Inhibiting nucleolin reduces inflammation induced by mitochondrial DNA in cardiomyocytes exposed to hypoxia and reoxygenation

G. Valen, J. Vaage, A. Baysa, 2019, British journal of pharmacology.

Isolated Plin5-deficient cardiomyocytes store less lipid droplets than normal, but without increased sensitivity to hypoxia.

A. Kimmel, F. Norheim, P. Khanal, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia.

M. Amiry-Moghaddam, G. Czibik, M. Bliksøen, 2013, Journal of molecular and cellular cardiology.

Hydrogen peroxide induces endothelial cell atypia and cytoskeleton depolymerization.

G. Valen, J. Vaage, A. Sondén, 1999, Free radical biology & medicine.

Protective effect of antioxidants on pulmonary endothelial function after cardiopulmonary bypass.

Mihkel Zilmer, J. Starkopf, J. Vaage, 2003, Journal of cardiothoracic and vascular anesthesia.

Inadvertent phosphorylation of survival kinases in isolated perfused hearts: a word of caution

M. Kaljusto, J. Vaage, K. Stensløkken, 2009, Basic Research in Cardiology.

Pulmonary hemodynamics and gas exchange in off pump coronary artery bypass grafting.

J. Vaage, A. Ericsson, J. Vedin, 2005, Interactive cardiovascular and thoracic surgery.

Fewer reoperations and shorter stay in the cardiac surgical ward when stabilising the sternum with the Ley prosthesis in post-operative mediastinitis.

J. Vaage, A. Karevold, B. Gårdlund, 2001, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Microvascular injury induced by intravascular platelet aggregation. An experimental study.

J. Vaage, 1994, Scandinavian journal of thoracic and cardiovascular surgery.

Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification

G. Sullivan, A. Malashicheva, A. Kostareva, 2017, Journal of the American Heart Association.

Different Notch signaling in cells from calcified bicuspid and tricuspid aortic valves.

G. Faggian, E. Ignatieva, A. Malashicheva, 2017, Journal of molecular and cellular cardiology.

Mitochondria‐derived damage‐associated molecular patterns and inflammation in the ischemic‐reperfused heart

J. Vaage, K. Stensløkken, M. Torp, 2023, Acta physiologica.

Exogenous reactive oxygen species deplete the isolated rat heart of antioxidants.

M. Antonelli, M. Bufi, A. Gasparetto, 1997, Free radical biology & medicine.

Postconditioning in rats and mice

M. Kaljusto, G. Valen, J. Vaage, 2006, Scandinavian cardiovascular journal : SCJ.

Mode of perfusion influences infarct size, coronary flow and stress kinases in the isolated mouse heart

M. Bliksøen, J. Vaage, K. Stensløkken, 2017, Acta physiologica.

Intermittent warm blood cardioplegia does not provide adequate myocardial resuscitation after global ischaemia.

J. Vaage, A. Ericsson, T. Kawakami, 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Intermittent warm blood cardioplegia does not provide adequate myocardial resuscitation after global ischaemia.

J. Vaage, A. Ericsson, T. Kawakami, 1999, European Journal of Cardio-Thoracic Surgery.

Intravascular platelet aggregation and acute respiratory insufficiency.

J. Vaage, 1977, Circulatory shock.

Retrograde cardioplegia: when and how. A review.

J. Vaage, 1993, Scandinavian journal of thoracic and cardiovascular surgery. Supplementum.

Higher TNFα responses in young males compared to females are associated with attenuation of monocyte adenylyl cyclase expression.

G. Valen, J. Vaage, A. Rutkovskiy, 2015, Human immunology.

Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis

P. Nilsson, A. Yndestad, S. Pischke, 2022, Frontiers in Immunology.

Letter: Prostaglandins and the pulmonary vasoconstrictor response to alveolar hypoxia.

J. Vaage, A. Hauge, 1975, Science.

Activity of histamine metabolizing and catabolizing enzymes during reperfusion of isolated, globally ischemic rat hearts

J. Kaszaki, G. Valen, J. Vaage, 1996, Inflammation Research.

Posters

I. Frerichs, G. Hellige, M. Dambrosio, 1996, Intensive Care Medicine.

Multi-omics of in vitro aortic valve calcification

A. Malashicheva, B. Thiede, A. Kostareva, 2022, Frontiers in Cardiovascular Medicine.

Lipopolysaccharide Induced Monocyte Thromboplastin Synthesis and Coagulation Responses in Patients Undergoing Coronary Bypass Surgery after Preoperative Supplementation with n-3 Fatty Acids

D. Nilsen, K. Rasmussen, J. Vaage, 1993, Thrombosis and Haemostasis.

Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo.

P. Nilsson, R. Islam, S. Pischke, 2023, Molecular immunology.

Myocardial protection evoked by hyperoxic exposure involves signaling through nitric oxide and mitogen activated protein kinases

G. Czibik, G. Valen, J. Vaage, 2006, Basic Research in Cardiology.

Negative results - Coronary Pulmonary hemodynamics and gas exchange in off pump coronary artery bypass grafting

J. Vaage, A. Ericsson, J. Vedin, 2005 .

Myocardial reperfusion injury: an inflammatory reaction?

A. Semb, J. Vaage, 1989, Biomedica biochimica acta.

Metabolic changes induced by ischemia and cardioplegia: a study employing cardiac microdialysis in pigs.

U. Ungerstedt, M. Goiny, A. Owall, 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein.

M. Mongillo, M. Giorgio, A. Maghazachi, 2022, Biochemical and biophysical research communications.

Lazaroid U-83836E improves tolerance to hemorrhagic shock and limb ischemia and reperfusion in rats and increases cardiac heat shock protein 72.

G. Valen, J. Vaage, F. Labruto, 2006, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

Prognostic factors in blunt chest trauma. Analysis of 652 cases.

J. Svennevig, J. Pillgram-Larsen, J. Vaage, 1986, Annales chirurgiae et gynaecologiae.

Cognitive function after on or off pump coronary artery bypass grafting.

H. Nyman, J. Vaage, A. Ericsson, 2006, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Effects of cardiac surgery on some clinically used inflammation markers and procalcitonin.

L. Hansson, G. Valen, J. Vaage, 2000, Scandinavian cardiovascular journal : SCJ.

Oxygen free radicals decrease survival time of isolated rat hearts.

A. Semb, J. Vaage, A. Ilebekk, 1989, Scandinavian journal of thoracic and cardiovascular surgery.

Poster session 2

Hugo A. Katus, V. V. Miroshnikova, Paolo Dario, 2004, EP Europace.

Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release

P. Nilsson, T. Woodruff, P. Garred, 2022, The Journal of Immunology.

Toxic oxygen metabolites induce vasoconstriction and bronchoconstriction in isolated, plasma‐perfused rat lungs

J. Vaage, L. Bjertnæs, J. Kjæve, 1991, Acta anaesthesiologica Scandinavica.

Does hypothermia or hyperkalemia influence the preconditioning response?

G. Valen, J. Vaage, C. Löwbeer, 1999, Scandinavian cardiovascular journal : SCJ.

Differential regulation of AMP-activated kinase and AKT kinase in response to oxygen availability in crucian carp (Carassius carassius).

G. Nilsson, S. Ellefsen, J. Vaage, 2008, American journal of physiology. Regulatory, integrative and comparative physiology.

Oxygen- and temperature-dependent expression of survival protein kinases in crucian carp (Carassius carassius) heart and brain.

G. Nilsson, J. Vaage, K. Stensløkken, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

Lipopolysaccharide lnduced Monocyte Thromboplastin Synthesis and Coagulation

D. Nilsen, K. Rasmussen, J. Vaage, 2018 .

[Blunt chest injuries].

J. Svennevig, J. Vaage, O. Geiran, 1984, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke.

Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia.

G. Czibik, M. Bliksøen, G. Valen, 2013, Journal of molecular and cellular cardiology.

Right ventricular and pulmonary artery pressure changes during off-pump coronary artery surgery: A-56

J. Vaage, S. Samuelsson, 2001 .