M. Goto

发表

Inactivating mutations of the human base excision repair gene NEIL1 in gastric cancer.

H. Sugimura, T. Takezaki, H. Igarashi, 2004, Carcinogenesis.

Absence of germline mono-allelic promoter hypermethylation of the CDH1 gene in gastric cancer patients

H. Sugimura, H. Konno, Hidetaka Yamada, 2009, Molecular Cancer.

Role of Base Excision Repair Enzyme MUTYH in the Repair of 8-Hydroxyguanine and MUTYH-Associated Polyposis (MAP)

H. Sugimura, H. Tao, K. Shinmura, 2012 .

In silico Evaluation of Nonsynonymous Single Nucleotide Polymorphisms in the TDG Gene, which is Involved in Base Excision Repair

H. Sugimura, Y. Inoue, K. Shinmura, 2014 .

Inverse relationship between the length of the EGFR CA repeat polymorphism in lung carcinoma and protein expression of EGFR in the carcinoma

H. Sugimura, Kazuya Suzuki, K. Takamochi, 2008, Journal of surgical oncology.

Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient

S. Ogawa, Motohiro Kato, H. Sugimura, 2008, Pathology international.

Three novel NEIL1 promoter polymorphisms in gastric cancer patients.

S. Tsugane, H. Sugimura, H. Tao, 2010, World journal of gastrointestinal oncology.

A novel STK11 germline mutation in two siblings with Peutz–Jeghers syndrome complicated by primary gastric cancer

H. Sugimura, H. Tao, K. Shinmura, 2004, Clinical genetics.

Quantitative detection of CpG methylation level on G-quadruplex and i-motif-forming DNA by recombinase polymerase amplification

M. Goto, Yuji Baba, W. Yoshida, 2022, Analytical and Bioanalytical Chemistry.

The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer

H. Sugimura, H. Konno, H. Igarashi, 2012, Journal of Translational Medicine.

Germline alterations in the CDH1 gene in familial gastric cancer in the Japanese population

M. Kasami, H. Sugimura, N. Sasaki, 2011, Cancer science.

Hepatocyte Mitogen‐Activated Protein Kinase Kinase 7 Contributes to Restoration of the Liver Parenchyma Following Injury in Mice

H. Nishina, J. Penninger, B. Xin, 2021, Hepatology (Baltimore, Md.).

Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts.

H. Nakagama, H. Sugimura, T. Matsuda, 2014, Free radical biology & medicine.

Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer

H. Sugimura, Masako Suzuki, H. Konno, 2015, Gastric Cancer.

Genetic susceptibility to lung cancer.

H. Sugimura, T. Matsuda, M. Tsuboi, 2011, Frontiers in bioscience.

NEIL1 p.Gln282Stop variant is predominantly localized in the cytoplasm and exhibits reduced activity in suppressing mutations.

H. Sugimura, H. Tao, Y. Inoue, 2015, Gene.

Aberrant Expression and Mutation-Inducing Activity of AID in Human Lung Cancer

H. Sugimura, M. Tanahashi, T. Matsuda, 2011, Annals of Surgical Oncology.

Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma

Hong Tao, Masanori Goto, Takayuki Sugiyama, 2017, Molecular carcinogenesis.

Detection of kinase amplifications in gastric cancer archives using fluorescence in situ hybridization

H. Sugimura, M. Tsuboi, N. Kurabe, 2012, Pathology international.

Altered expression of the human base excision repair gene NTH1 in gastric cancer.

S. Tsugane, H. Sugimura, H. Konno, 2009, Carcinogenesis.

Fluorescence-labeled methylation-sensitive amplified fragment length polymorphism (FL-MS-AFLP) analysis for quantitative determination of DNA methylation and demethylation status.

H. Sugimura, K. Shinmura, Hiroko Yamamoto, 2008, Japanese journal of clinical oncology.

PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer

Masanori Goto, Hiroyuki Konno, H. Sugimura, 2014, Molecular Biology Reports.

The CRKL gene encoding an adaptor protein is amplified, overexpressed, and a possible therapeutic target in gastric cancer

H. Sugimura, H. Konno, H. Igarashi, 2012, Journal of Translational Medicine.

Reduced expression of MUTYH with suppressive activity against mutations caused by 8‐hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer

Tomonari Matsuda, Hong Tao, Masanori Goto, 2011, The Journal of pathology.

Adenine DNA Glycosylase Activity of 14 Human MutY Homolog (MUTYH) Variant Proteins Found in Patients with Colorectal Polyposis and Cancer

Y. Nakabeppu, H. Sugimura, H. Tao, 2010, Human mutation.

Identification and characterization of a novel germ line p53 mutation in familial gastric cancer in the Japanese population.

H. Sugimura, Hidetaka Yamada, K. Shinmura, 2007, Carcinogenesis.

Hypermutation and unique mutational signatures of occupational cholangiocarcinoma in printing workers exposed to haloalkanes

Yutaka Suzuki, T. Shibata, S. Marubashi, 2016, Carcinogenesis.

Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma.

H. Sugimura, M. Tanahashi, Kazuya Suzuki, 2011, Lung cancer.

Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5‐hydroxyuracil, an oxidation product of cytosine

H. Sugimura, H. Tao, K. Shinmura, 2019, Free radical biology & medicine.

Emergence of the Dedifferentiated Phenotype in Hepatocyte‐Derived Tumors in Mice: Roles of Oncogene‐Induced Epigenetic Alterations

H. Furukawa, B. Xin, M. Goto, 2019, Hepatology communications.

Urinary β2-Microglobulin in Behçet’s Disease

Atsuhiro Kanno, K. Furukawa, M. Goto, 2021 .

Further Characterization of PL-1 Phage-associated N-Acetylmuramidase of Lactobacillus casei

Kenji Watanabe, M. Goto, T. Muramatsu, 1987 .

Defective repair capacity of variant proteins of the DNA glycosylase NTHL1 for 5‐hydroxyuracil, an oxidation product of cytosine

H. Sugimura, H. Tao, K. Shinmura, 2019, Free radical biology & medicine.

Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells

H. Sugimura, H. Tao, Y. Inoue, 2017, Oxidative medicine and cellular longevity.

Functional Evaluation of Nine Missense‐Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population

H. Sugimura, H. Tao, Hidetaka Yamada, 2016, Human mutation.

Lipid peroxidation-induced DNA adducts in human gastric mucosa.

H. Sugimura, T. Matsuda, H. Konno, 2013, Carcinogenesis.

OGG1, MYH and MTH1 gene variants identified in gastric cancer patients exhibiting both 8-hydroxy-2′-deoxyguanosine accumulation and low inflammatory cell infiltration in their gastric mucosa

H. Sugimura, Hidetaka Yamada, K. Shinmura, 2008, Journal of Genetics.

Hepatocyte Mitogen‐Activated Protein Kinase Kinase 7 Contributes to Restoration of the Liver Parenchyma Following Injury in Mice

H. Nishina, J. Penninger, B. Xin, 2020, Hepatology.

Generation of combined hepatocellular‐cholangiocarcinoma through transdifferentiation and dedifferentiation in p53‐knockout mice

B. Xin, M. Goto, T. Ooshio, 2021, Cancer science.

Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis.

H. Sugimura, T. Matsuda, H. Tao, 2012, World journal of gastroenterology.

Impaired 8-Hydroxyguanine Repair Activity of MUTYH Variant p.Arg109Trp Found in a Japanese Patient with Early-Onset Colorectal Cancer

H. Sugimura, S. Kono, M. Morita, 2014, Oxidative medicine and cellular longevity.

PLK4 overexpression and its effect on centrosome regulation and chromosome stability in human gastric cancer

H. Sugimura, H. Konno, N. Kurabe, 2014, Molecular Biology Reports.

Abnormal Expressions of DNA Glycosylase Genes NEIL1, NEIL2, and NEIL3 Are Associated with Somatic Mutation Loads in Human Cancer

H. Sugimura, H. Igarashi, H. Tao, 2016, Oxidative medicine and cellular longevity.

Characterization of adenocarcinoma of the lung in a familial adenomatous polyposis patient

S. Ogawa, H. Sugimura, Kazuya Suzuki, 2008, Pathology international.