J. Harrigan

发表

The Human Werner Syndrome Protein Stimulates Repair of Oxidative DNA Base Damage by the DNA Glycosylase NEIL1*

V. Bohr, S. Mitra, I. Boldogh, 2007, Journal of Biological Chemistry.

Human diseases deficient in RecQ helicases.

V. Bohr, J. Harrigan, 2003, Biochimie.

Replication stress induces 53BP1-containing OPT domains in G1 cells

C. Bradshaw, P. Fraser, S. Jackson, 2011, The Journal of cell biology.

Metal-catalyzed Oxidation of the Werner Syndrome Protein Causes Loss of Catalytic Activities and Impaired Protein-Protein Interactions*

V. Bohr, R. Levine, J. Harrigan, 2007, Journal of Biological Chemistry.

Cooperation of the Cockayne Syndrome Group B Protein and Poly(ADP-Ribose) Polymerase 1 in the Response to Oxidative Stress

V. Bohr, M. Christiansen, T. Thorslund, 2005, Molecular and Cellular Biology.

Oxidative Stress.

Dean P. Jones, V. Bohr, H. Sies, 2017, Annual review of biochemistry.

Monitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future

X. Jacq, J. Harrigan, 2016, Methods in molecular biology.

Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity

Edward W. Tate, E. Tate, Aurélien Godinat, 2019, Journal of the American Chemical Society.

Quantitative Chemical Proteomic Profiling of Ubiquitin Specific Proteases in Intact Cancer Cells.

Jennifer A. Ward, X. Jacq, E. Tate, 2016, ACS chemical biology.

Activity Based Profiling of Deubiquitylating Enzymes and Inhibitors in Animal Tissues.

X. Jacq, J. Harrigan, A. Cranston, 2016, Methods in molecular biology.

Proposed Biological Functions for the Werner Syndrome Protein in DNA Metabolism

V. Bohr, W. Cheng, R. Brosh, 2004 .

The human Werner Syndrome as a model system for aging

W. Cheng, J. Harrigan, P. Opresko, 2004 .

The Werner Syndrome Protein Stimulates DNA Polymerase β Strand Displacement Synthesis via Its Helicase Activity*

Samuel H. Wilson, V. Bohr, R. Prasad, 2003, Journal of Biological Chemistry.

WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand

D. Ramsden, V. Bohr, B. Tudek, 2008, Nucleic acids research.

The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage

I. Stagljar, R. Jiao, V. Bohr, 2007, Oncogene.

Deubiquitylating enzymes and drug discovery: emerging opportunities

Stephen P. Jackson, X. Jacq, S. Jackson, 2017, Nature Reviews Drug Discovery.

Pathways and functions of the Werner syndrome protein

V. Bohr, Jae Wan Lee, J. Harrigan, 2005, Mechanisms of Ageing and Development.

Werner protein stimulates topoisomerase I DNA relaxation activity.

V. Bohr, J. Lainé, F. Indig, 2003, Cancer research.

Telomere-binding Protein TRF2 Binds to and Stimulates the Werner and Bloom Syndrome Helicases*

I. Hickson, V. Bohr, J. Lainé, 2002, The Journal of Biological Chemistry.

WRN exonuclease activity is blocked by DNA termini harboring 3′ obstructive groups

Jinshui Fan, J. Momand, V. Bohr, 2007, Mechanisms of Ageing and Development.

The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β

Samuel H. Wilson, V. Bohr, R. Prasad, 2006, Nucleic acids research.

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

V. Bohr, W. Cheng, J. Harrigan, 2003, Carcinogenesis.

WERNER SYNDROME AND THE FUNCTION OF

V. Bohr, W. Cheng, J. Harrigan, 2003 .

A population-based analysis of germline BAP1 mutations in melanoma

D. Bishop, D. Adams, X. Jacq, 2017, Human molecular genetics.

Regulation of WRN Helicase Activity in Human Base Excision Repair*

V. Bohr, B. Ahn, F. Indig, 2004, Journal of Biological Chemistry.

A population-based analysis of germline BAP 1 mutations in melanoma

D. Bishop, D. Adams, X. Jacq, 2017 .

Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

V. Bohr, W. Cheng, A. May, 2003, Molecular and Cellular Biology.

Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.

P. Stiegler, V. Schreiber, V. Bohr, 2004, Nucleic acids research.

Activity-based protein profiling reveals deubiquitinase and aldehyde dehydrogenase targets of a cyanopyrrolidine probe

Aditya R. Thawani, E. Tate, Aurélien Godinat, 2021, RSC medicinal chemistry.

Correction to “Discovery of a Potent and Selective Covalent Inhibitor and Activity-Based Probe for the Deubiquitylating Enzyme UCHL1, with Antifibrotic Activity”

E. Tate, Aurélien Godinat, M. Mondal, 2020, Journal of the American Chemical Society.

Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients

E. Metter, M. Gray, V. Bohr, 2004, Mechanisms of Ageing and Development.

Replication stress induces 53BP1-containing OPT domains in G1 cells

C. Bradshaw, P. Fraser, R. Belotserkovskaya, 2011, The Journal of cell biology.