Leonidas G. Alexopoulos

发表

Modeling pro-death signaling pathways in cancer hepatocytes using multi-combinatorial treatments of inhibitors and stimuli

Peter K. Sorger, Douglas A. Lauffenburger, Leonidas G. Alexopoulos, 2008, 2008 8th IEEE International Conference on BioInformatics and BioEngineering.

A crowd-sourcing approach for the construction of species-specific cell signaling networks

Theodore Sakellaropoulos, Erhan Bilal, Pablo Meyer, 2014, Bioinform..

A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

Mats G. Gustafsson, Leonidas G. Alexopoulos, Michael Neidlin, 2020, Annals of Biomedical Engineering.

Non Linear Programming (NLP) Formulation for Quantitative Modeling of Protein Signal Transduction Pathways

Julio Saez-Rodriguez, Alexander Mitsos, Douglas A. Lauffenburger, 2012, PloS one.

Dynamics and heterogeneity of brain damage in multiple sclerosis

Roland Martin, Pablo Villoslada, Jesper Tegnér, 2017, PLoS Comput. Biol..

Construction of Signaling Pathways and Identification of Drug Effects via Phosphoproteomic Experiments and Combinatorial Optimization

Alexander Mitsos, Leonidas G. Alexopoulos, 2010 .

Crowdsourcing Network Inference: The DREAM Predictive Signaling Network Challenge

Julio Saez-Rodriguez, Peter K. Sorger, Gustavo Stolovitzky, 2011, Science Signaling.

Modeling signaling pathways in articular cartilage

Alexander Mitsos, Leonidas G. Alexopoulos, Christopher G. Provatidis, 2011, 2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Network Reconstruction Based on Proteomic Data and Prior Knowledge of Protein Connectivity Using Graph Theory

Theodore Sakellaropoulos, Vassilis Stavrakas, Leonidas G. Alexopoulos, 2015, PloS one.

Combined logical and data-driven models for linking signalling pathways to cellular response

Alexander Mitsos, Leonidas G. Alexopoulos, Ioannis N. Melas, 2011, BMC Systems Biology.

Designing Experiments to Discriminate Families of Logic Models

Torsten Schaub, Julio Saez-Rodriguez, Carito Guziolowski, 2015, Front. Bioeng. Biotechnol..

The Logic of EGFR/ErbB Signaling: Theoretical Properties and Analysis of High-Throughput Data

Steffen Klamt, Julio Saez-Rodriguez, Peter K. Sorger, 2009, PLoS Comput. Biol..

Detecting and Removing Inconsistencies between Experimental Data and Signaling Network Topologies Using Integer Linear Programming on Interaction Graphs

Steffen Klamt, Leonidas G. Alexopoulos, Ioannis N. Melas, 2013, PLoS Comput. Biol..

Identification of signaling pathways related to drug efficacy in hepatocellular carcinoma via integration of phosphoproteomic, genomic and clinical data

Douglas A. Lauffenburger, Leonidas G. Alexopoulos, Ioannis N. Melas, 2013, 13th IEEE International Conference on BioInformatics and BioEngineering.

Identifying Drug Effects via Pathway Alterations using an Integer Linear Programming Optimization Formulation on Phosphoproteomic Data

Julio Saez-Rodriguez, Alexander Mitsos, Leonidas G. Alexopoulos, 2009, PLoS Comput. Biol..

Flexible informatics for linking experimental data to mathematical models via DataRail

Julio Saez-Rodriguez, Peter K. Sorger, Douglas A. Lauffenburger, 2008, Bioinform..

Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Erhan Bilal, Pablo Meyer, Raquel Norel, 2014, Bioinform..

‡Please address correspondence to:

Julio Saez-Rodriguez, Leonidas G. Alexopoulos, Christopher W. Espelin, 2022 .

A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytes

Linda G. Griffith, Julio Saez-Rodriguez, Douglas A. Lauffenburger, 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Towards a Rigorous Assessment of Systems Biology Models: The DREAM3 Challenges

Daniel Marbach, Julio Saez-Rodriguez, Peter K. Sorger, 2010, PloS one.