E. Wood

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Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II

W. Earnshaw, E. Wood, 1990, The Journal of cell biology.

ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure

W. Earnshaw, N. Saitoh, E. Wood, 1994, The Journal of cell biology.

The molecular cloning of the gene encoding the Escherichia coli 75-kDa helicase and the determination of its nucleotide sequence and gentic map position.

S. W. Matson, E. Wood, 1989, The Journal of biological chemistry.

Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

S. Frye, M. Machius, M. Miley, 2017, ChemMedChem.

Hepatocytes and macrophages express an identical cytokine inducible nitric oxide synthase gene.

E. Lapetina, E. Wood, H. Berger, 1993, Biochemical and biophysical research communications.

Quantitative analysis of SH2 domain binding. Evidence for specificity and competition.

E. Wood, O. McDonald, N. Sahyoun, 1992, The Journal of biological chemistry.

The discovery of potent cRaf1 kinase inhibitors.

P. A. Harris, S. Frye, K. Lackey, 2000, Bioorganic & medicinal chemistry letters.

Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase.

G. Warren, R. Copeland, T. J. Lansing, 2008, Journal of medicinal chemistry.

Synthesis and evaluation of aniline headgroups for alkynyl thienopyrimidine dual EGFR/ErbB-2 kinase inhibitors.

A. Waterson, R. Griffin, K. Hinkle, 2009, Bioorganic & medicinal chemistry letters.

Synthesis and stereochemical effects of pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines as EGFR and ErbB-2 inhibitors.

A. Waterson, R. Griffin, D. Uehling, 2009, Bioorganic & medicinal chemistry letters.

Dual EGFR/ErbB-2 inhibitors from novel pyrrolidinyl-acetylenic thieno[3,2-d]pyrimidines.

A. Waterson, R. Griffin, D. Uehling, 2008, Bioorganic & medicinal chemistry letters.

A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)

Krystal J Alligood, Karen Lackey, K. Lackey, 2004, Cancer Research.

Discovery and in vitro evaluation of potent kinase inhibitors: Pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidines.

K. Lackey, Laurie S. Kane-Carson, E. Wood, 2005, Bioorganic & medicinal chemistry letters.

6-Ethynylthieno[3,2-d]- and 6-ethynylthieno[2,3-d]pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases

Edgar R. Wood, Robert J. Griffin, Michael J. Reno, 2008, Proceedings of the National Academy of Sciences.

Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series.

K. Lackey, R. Mook, A. Walker, 2006, Bioorganic & medicinal chemistry letters.

Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line.

V. Laubach, E. Wood, P. Sherman, 1993, Biochemistry.

The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.

K. Lackey, T. Gilmer, E. Wood, 2001, Molecular cancer therapeutics.

Tandem Michael‐addition/cyclization synthesis and EGFR kinase inhibition activity of pyrido[2,3‐d]pyrimidin‐7(8H)‐ones

A. Sefler, T. Spitzer, E. Wood, 2004 .

Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity.

Robert A Copeland, Anthony E Choudhry, T. Gilmer, 2008, Cancer research.

Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor.

E. Alvarez, L. Shewchuk, H. Xie, 2009, Biochemical pharmacology.

Impact of common epidermal growth factor receptor and HER2 variants on receptor activity and inhibition by lapatinib.

L. Shewchuk, T. Gilmer, A. Truesdale, 2008, Cancer research.

Comparison of the Biochemical and Kinetic Properties of the Type 1 Receptor Tyrosine Kinase Intracellular Domains

K. Lackey, K. Blackburn, S. Kadwell, 2002, The Journal of Biological Chemistry.

A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors.

A. Smith, W. J. Chen, E. Wood, 1999, Analytical biochemistry.

The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors*

Cecil E. Rise, B. Wisely, T. Sheahan, 2015, The Journal of Biological Chemistry.

Cell-based assays for kinase drug discovery.

E. Wood, Gary K. Smith, 2010, Drug discovery today. Technologies.

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer.

K. Lackey, T. Gilmer, R. Crosby, 2001, Cancer research.

Purification and characterization of a new DNA-dependent ATPase with helicase activity from Escherichia coli.

S. W. Matson, E. Wood, 1987, The Journal of biological chemistry.

Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors.

D. Vanderwall, L. Shewchuk, A. Goetz, 2009, Bioorganic & medicinal chemistry letters.

2,3,5-Trisubstituted pyridines as selective AKT inhibitors-Part I: Substitution at 2-position of the core pyridine for ROCK1 selectivity.

J. Luengo, D. Yamashita, D. Heerding, 2010, Bioorganic & medicinal chemistry letters.

Genetic responses of the thermophilic archaeon Sulfolobus acidocaldarius to short-wavelength UV light

D. Grogan, E. Wood, F. Ghane, 1997, Journal of bacteriology.

Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles.

Karen Lackey, P. A. Harris, L. Kuyper, 2004, Bioorganic & medicinal chemistry letters.

Escherichia coli Rep protein and helicase IV. Distributive single-stranded DNA-dependent ATPases that catalyze a limited unwinding reaction in vitro.

S. W. Matson, K. Smith, E. Wood, 1992, European journal of biochemistry.

Expression of a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in rat thymus.

T. Chatila, E. Wood, N. Sahyoun, 1991, The Journal of biological chemistry.

Association of phosphorylated insulin-like growth factor-I receptor with the SH2 domains of phosphatidylinositol 3-kinase p85.

E. Lapetina, E. Wood, K. Yamamoto, 1992, The Journal of biological chemistry.

Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.

S. Frye, M. Machius, M. Miley, 2016, ACS medicinal chemistry letters.

Aza-stilbenes as potent and selective c-RAF inhibitors.

K. Lackey, R. Hunter, Ronda G. Davis-Ward, 2006, Bioorganic & medicinal chemistry letters.

Discovery and in vitro Evaluation of Potent TrkA Kinase Inhibitors: Oxindole and Aza‐Oxindoles.

L. Kuyper, K. Lackey, R. Hunter, 2004 .

Discovery and biological evaluation of potent dual ErbB-2/EGFR tyrosine kinase inhibitors: 6-thiazolylquinazolines.

K. Lackey, T. Gilmer, R. Griffin, 2003, Bioorganic & medicinal chemistry letters.

Purification and characterization of the constitutive nitric oxide synthase from human placenta.

I. Charles, E. Garvey, S. Baylis, 1994, Archives of biochemistry and biophysics.

Discovery of Macrocyclic Pyrimidines as MerTK‐Specific Inhibitors

S. Frye, M. Machius, M. Miley, 2017, ChemMedChem.