N. Cooke

发表

Locus control region transcription plays an active role in long-range gene activation.

S. Liebhaber, Y. Ho, F. Elefant, 2006, Molecular cell.

Human prolactin. cDNA structural analysis and evolutionary comparisons.

D Coit, J D Baxter, J. Shine, 1981, The Journal of biological chemistry.

G. Levan, C. Szpirer, N. Cooke, 1986, Endocrinology.

The role of the hGH locus control region in somatotrope restriction of hGH-N gene expression.

S. Liebhaber, Y. Ho, N. Cooke, 2011, Molecular endocrinology.

Developmental control and alternative splicing of the placentally expressed transcripts from the human growth hormone gene cluster.

J. MacLeod, S. Liebhaber, N. Cooke, 1992, The Journal of biological chemistry.

Specification of unique Pit-1 activity in the hGH locus control region

S. Liebhaber, N. Cooke, B. Shewchuk, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Vitamin D-binding Protein Gene Transcription Is Regulated by the Relative Abundance of Hepatocyte Nuclear Factors 1α and 1β*

S. Liebhaber, K. Ray, N. Cooke, 1998, The Journal of Biological Chemistry.

Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo.

B. Hollis, J. Pike, Lee A. Zella, 2008, Endocrinology.

Human growth hormone variant produces insulin-like and lipolytic responses in rat adipose tissue.

S. Liebhaber, L. Tai, H. Goodman, 1991, Endocrinology.

Identification of a splice-site mutation in the human growth hormone-variant gene.

J. MacLeod, S. Liebhaber, N. Cooke, 1991, American journal of human genetics.

Glycosylated human growth hormone variant.

S. Liebhaber, N. Cooke, J. Ray, 1989, Endocrinology.

Human growth hormone gene and the highly homologous growth hormone variant gene display different splicing patterns.

M. Watson, S. Liebhaber, P. Estes, 1988, The Journal of clinical investigation.

Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript.

M. Urbanek, J. MacLeod, S. Liebhaber, 1992, Molecular endocrinology.

Characterization and histologic localization of human growth hormone-variant gene expression in the placenta.

M. Urbanek, S. Liebhaber, R. Tuan, 1989, The Journal of clinical investigation.

Cell surface vitamin D-binding protein (GC-globulin) is acquired from plasma.

R. M. Smith, J. Haddad, N. Cooke, 1990, Endocrinology.

Vitamin D binding protein: Genomic structure, functional domains, and mRNA expression in tissues

K. Ray, N. Cooke, Xinkang Wang, 1991, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D binding protein (Gc-globulin).

J. Haddad, N. Cooke, Nancy E. Cooke, 1989, Endocrine reviews.

The prolactin gene is located on chromosome 6 in humans.

W. Rutter, T. Shows, J. Martial, 1981, Science.

Analysis of the human cysteine-rich protein gene (CSRP), assignment to chromosome 1q24-1q32, and identification of an associated MspI polymorphism.

S. Liebhaber, K. Ray, G. Levan, 1992, Genomics.

Rat vitamin D binding protein. Determination of the full-length primary structure from cloned cDNA.

N. Cooke, 1986, The Journal of biological chemistry.

Direct regional assignment of the gene for vitamin D binding protein (Gc-globulin) to human chromosome 4q11-q13 and identification of an associated DNA polymorphism

H. Willard, D. George, N. Cooke, 1986, Human Genetics.

Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.

S. Liebhaber, N. Cooke, I. Bennani-Baiti, 1995, Genomics.

Human serum binding protein for vitamin D and its metabolites. I. Physicochemical and immunological identification in human tissues.

J. Haddad, N. Cooke, J. Walgate, 1979, The Journal of biological chemistry.

Human serum binding protein for vitamin D and its metabolites. II. Specific, high affinity association with a protein in nucleated tissue.

J. Haddad, N. Cooke, J. Walgate, 1979, The Journal of biological chemistry.

DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression.

S. Asa, D. Song, S. Liebhaber, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Structure of cloned DNA complementary to rat prolactin messenger RNA.

J. Martial, J. Baxter, N. Cooke, 1980, The Journal of biological chemistry.

Functional characterization of a human POU1F1 mutation associated with isolated growth hormone deficiency: a novel etiology for IGHD.

S. Liebhaber, S. Amselem, B. Stanger, 2016, Human Molecular Genetics.

The Role of the Serum Vitamin D Binding Protein in the Actions of the Vitamin D Analog Eldecalcitol (ED-71) on Bone and Mineral Metabolism

N. Cooke, C. Ritter, Fanjie Zhang, 2013, Calcified Tissue International.

Research resource: T-antigen transformation of pituitary cells captures three novel cell lines in the Pit-1 lineage.

S. Liebhaber, D. Sizova, Y. Ho, 2010, Molecular endocrinology.

Expression of the prolactin gene in human decidua-chorion.

J. Shine, J. Clements, N. Cooke, 1983, Endocrinology.

Electrophoretic mobility shift assay identifies vitamin D binding protein (Gc-globulin) in human, rat, and mouse sera.

J. Haddad, N. Cooke, H. Bazaraa, 1996, Analytical biochemistry.

The rat vitamin D binding protein (Gc-globulin) gene is syntenic with the rat albumin and alpha-fetoprotein genes on chromosome 14.

G. Levan, J. Szpirer, N. Cooke, 1987, Cytogenetics and cell genetics.

Human growth hormone-variant is a biologically active somatogen and lactogen.

J. MacLeod, S. Liebhaber, H. Friesen, 1991, Endocrinology.

Human growth hormone-variant demonstrates a receptor binding profile distinct from that of normal pituitary growth hormone.

P. Kelly, S. Liebhaber, H. Okamura, 1990, The Journal of biological chemistry.

Characterization of a human cDNA encoding a widely expressed and highly conserved cysteine-rich protein with an unusual zinc-finger motif

S. A. Liebhaber, J. G. Emery, M. Urbanek, 1990, Nucleic Acids Res..

The Multifunctional Properties and Characteristics of Vitamin D-binding Protein

P. White, N. Cooke, 2000, Trends in Endocrinology & Metabolism.

Electrochemistry of tantalum bromide cluster compound

T. Kuwana, N. Cooke, J. Espenson, 1971 .

Neurobeachin regulates neurotransmitter receptor trafficking to synapses

M. Verhage, J. Rhee, N. Brose, 2013, The Journal of cell biology.

Neurobeachin regulates transmitter receptor trafficking to synapses

M. Verhage, J. Rhee, N. Brose, 2013 .

CHAPTER 8 – Vitamin D–Binding Protein

C. J. Laing, N. Cooke, 2005 .

Serum vitamin D-binding protein is a third member of the albumin and alpha fetoprotein gene family.

N. Cooke, E. David, 1985, The Journal of clinical investigation.

The vitamin D-binding protein, alpha-fetoprotein, albumin multigene family: detection of transcripts in multiple tissues.

N. Cooke, J. McLeod, 1989, The Journal of biological chemistry.

Vitamin D‐Binding Protein

N. Cooke, A. Murgia, J. McLeod, 1988 .

Identification of the sterol- and actin-binding domains of plasma vitamin D binding protein (Gc-globulin).

K. Ray, J. Haddad, N. Cooke, 1992, Biochemistry.

categoriesexpression reprogramming in key gene function Microarray analysis of trophoblast differentiation

D. Charnock-Jones, Stephen K. Smith, B. Aronow, 2015 .

Epigenetic Activation of the Human Growth Hormone Gene Cluster during Placental Cytotrophoblast Differentiation

S. Liebhaber, A. Kimura, S. Handwerger, 2007, Molecular and Cellular Biology.

Structural analysis of the prolactin gene suggests a separate origin for its 5′ end

J. Baxter, N. Cooke, 1982, Nature.

The human vitamin D-binding protein gene contains locus control determinants sufficient for autonomous activation in hepatic chromatin

S. Liebhaber, N. Cooke, Young-Han Song, 2006, Nucleic acids research.

Two distinct species of human growth hormone-variant mRNA in the human placenta predict the expression of novel growth hormone proteins.

S. Liebhaber, J. Ray, N. Cooke, 1988, The Journal of biological chemistry.

Molecular biology of the growth hormone-prolactin gene system.

S. Liebhaber, N. Cooke, 1995, Vitamins and hormones.

Igβ(CD79b) mRNA expression in chronic lymphocytic leukaemia cells correlates with immunoglobulin heavy chain gene mutational status but does not serve as an independent predictor of clinical severity

A. Bagg, R. Elstrom, S. Liebhaber, 2007, American journal of hematology.

An Autoregulatory Pathway Establishes the Definitive Chromatin Conformation at the Pit-1 Locus

S. Liebhaber, Y. Ho, N. Cooke, 2015, Molecular and Cellular Biology.

Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster.

S. Liebhaber, A. Naumova, Y. Song, 1999, Genome research.

Distinct Chromatin Configurations Regulate the Initiation and the Maintenance of hGH Gene Expression

S. Liebhaber, Y. Ho, N. Cooke, 2013, Molecular and Cellular Biology.

Assignment of three rat genes coding for plasma proteins, transferrin, third component of complement, and beta-fibrinogen to rat chromosomes 8, 9, and 2.

G. Levan, C. Szpirer, J. Szpirer, 1988, Cytogenetics and cell genetics.

Regulation of Growth Hormone Gene Expression

S. Liebhaber, N. Cooke, 2011 .

The Human Growth Hormone Gene Cluster Locus Control Region Supports Position-independent Pituitary- and Placenta-specific Expression in the Transgenic Mouse*

S. Liebhaber, N. Cooke, Yuhua Su, 2000, The Journal of Biological Chemistry.

Gestational Physiology of the Growth Hormone Gene Family

M. Urbanek, S. Liebhaber, N. Cooke, 1995 .

Placental Expression and Function of the Human Growth Hormone Gene Cluster

M. Urbanek, J. MacLeod, S. Liebhaber, 1993 .

Alteration in the receptor binding specificity of human growth hormone by genomic exon exchange.

P. Kelly, S. Liebhaber, H. Okamura, 1990, Molecular endocrinology.

Mechanisms for Evolutionary Divergence within the Prolactin Gene Family

N. Cooke, 1984 .

Identification of a Secondary Promoter within the Human B Cell Receptor Component Gene hCD79b*

S. Liebhaber, N. Cooke, E. Yoo, 2013, The Journal of Biological Chemistry.

Identification of a Secondary Promoter within the Human B-Cell Receptor Component Gene, hCD79b *

S. Liebhaber, N. Cooke, E. Yoo, 2013 .

The LIM/double zinc-finger motif functions as a protein dimerization domain.

D. Song, S. Liebhaber, N. Cooke, 1994, Proceedings of the National Academy of Sciences of the United States of America.

An RNA-Independent Linkage of Noncoding Transcription to Long-Range Enhancer Function

S. Liebhaber, N. Cooke, E. Yoo, 2012, Molecular and Cellular Biology.

Long-range looping of a locus control region drives tissue-specific chromatin packing within a multigene cluster

S. Liebhaber, N. Cooke, Y. Tsai, 2016, Nucleic acids research.

Tissue specific CTCF occupancy and boundary function at the human growth hormone locus

S. Liebhaber, N. Cooke, Y. Tsai, 2014, Nucleic acids research.

The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression

S. Liebhaber, Y. Ho, N. Cooke, 2008, EMBO reports.

Tissue-Specific Chromatin Modifications at a Multigene Locus Generate Asymmetric Transcriptional Interactions

S. Liebhaber, A. Kimura, N. Cooke, 2006, Molecular and Cellular Biology.

Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation.

S. Liebhaber, A. Kimura, N. Cooke, 2004, Molecular endocrinology.

Activation of the human GH gene cluster: roles for targeted chromatin modification

S. Liebhaber, Y. Ho, N. Cooke, 2004, Trends in Endocrinology & Metabolism.

A defined locus control region determinant links chromatin domain acetylation with long-range gene activation.

S. Liebhaber, Y. Ho, F. Elefant, 2002, Molecular cell.

Targeted Recruitment of Histone Acetyltransferase Activity to a Locus Control Region*

S. Liebhaber, F. Elefant, N. Cooke, 2000, Journal of Biological Chemistry.

Pit-1 Binding Sites at the Somatotrope-specific DNase I Hypersensitive Sites I, II of the Human Growth Hormone Locus Control Region Are Essential for in Vivo hGH-N Gene Activation*

S. Asa, S. Liebhaber, N. Cooke, 1999, The Journal of Biological Chemistry.

Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene.

S. Liebhaber, N. Cooke, I. Bennani-Baiti, 1998, Genomics.

The human growth hormone gene is regulated by a multicomponent locus control region

S. Liebhaber, B. Monks, N. Cooke, 1995, Molecular and cellular biology.

A native RNA secondary structure controls alternative splice-site selection and generates two human growth hormone isoforms.

S. Liebhaber, P. Estes, N. Cooke, 1992, The Journal of biological chemistry.

An Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene

S. Liebhaber, N. Cooke, Tomoko Hiroki, 2007, Molecular and Cellular Biology.

129X1/SvJ Mouse Strain Has a Novel Defect in Inflammatory Cell Recruitment1

P. White, S. Liebhaber, N. Cooke, 2002, The Journal of Immunology.

The rat vitamin D binding protein (Gc-globulin) gene. Structural analysis, functional and evolutionary correlations.

K. Ray, N. Cooke, X. Wang, 1991, The Journal of biological chemistry.

Binding of human growth hormone (GH)-variant (placental GH) to GH-binding proteins in human plasma.

S. Liebhaber, M. Shaw, G. Baumann, 1991, The Journal of clinical endocrinology and metabolism.

The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regions.

S. Liebhaber, N. Cooke, B. Shewchuk, 2001, Nucleic acids research.

Complex alternative splicing partially inactivates the human chorionic somatomammotropin-like (hCS-L) gene.

S. Liebhaber, N. Cooke, A. Misra-press, 1994, The Journal of biological chemistry.

Synapse Associated Protein 102 (SAP102) Binds the C-Terminal Part of the Scaffolding Protein Neurobeachin

A. Smit, M. Verhage, R. Toonen, 2012, PloS one.

Neurobeachin Is Essential for Neuromuscular Synaptic Transmission

J. Golden, R. Balice-Gordon, S. Liebhaber, 2004, The Journal of Neuroscience.

An RNA-independent Linkage of Non-coding Transcription to

S. Liebhaber, N. Cooke, E. Yoo, 2012 .

Bystander gene activation by a locus control region

S. Liebhaber, N. Cooke, Isabela Cajiao, 2004, The EMBO journal.

DNase I Hypersensitive Site II of the Human Growth Hormone Locus Control Region Mediates an Essential and Distinct Long-range Enhancer Function*

S. Liebhaber, Y. Ho, N. Cooke, 2012, The Journal of Biological Chemistry.

Locus Control Regions, Human

S. Liebhaber, N. Cooke, 2002 .

Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region

S. Liebhaber, F. Elefant, N. Cooke, 2000, The EMBO journal.

Human cysteine-rich protein. A member of the LIM/double-finger family displaying coordinate serum induction with c-myc.

S. Liebhaber, N. Cooke, S A Liebhaber, 1992, The Journal of biological chemistry.

Autonomous actions of the human growth hormone long-range enhancer

Christopher D. Brown, S. Liebhaber, N. Cooke, 2015, Nucleic acids research.

Functional characterization of the alternatively spliced, placental human growth hormone receptor.

M. Urbanek, S. Liebhaber, N. Cooke, 1993, The Journal of biological chemistry.

Isolation and sequence analysis of the rat prolactin structural gene

J. Martial, N. Cooke, 1980 .

Hypercalcaemia in adolescent tetraplegic patients: case report and review

S. Birge, N. Cooke, F. Steinberg, 1978, Paraplegia.

Osteopathy and resistance to vitamin D toxicity in mice null for vitamin D binding protein.

S. Liebhaber, B. Hollis, M. Gentile, 1999, The Journal of clinical investigation.

Molecular characterization of a major nephritogenic domain in the autoantigen of anti-tubular basement membrane disease.

T. Haverty, E. Neilson, N. Cooke, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Vitamin D binding protein is required to utilize skin-generated vitamin D

H. DeLuca, N. Cooke, J. Seeman, 2019, Proceedings of the National Academy of Sciences.

Neutrophil Recruitment to the Lung in Both C5a- and CXCL1-Induced Alveolitis Is Impaired in Vitamin D–Binding Protein–Deficient Mice

N. Cooke, D. Habiel, Mahalakshmi Ramadass, 2013, The Journal of Immunology.

The Role of the Serum Vitamin D Binding Protein in the Actions of the Vitamin D Analog Eldecalcitol (ED-71) on Bone and Mineral Metabolism

Alex J. Brown, N. Cooke, C. Ritter, 2013, Calcified Tissue International.

A Single Base Difference between Pit-1 Binding Sites at the hGH Promoter and Locus Control Region Specifies Distinct Pit-1 Conformations and Functions

S. Liebhaber, Y. Ho, N. Cooke, 2006, Molecular and Cellular Biology.

Synthesis of growth hormone-prolactin chimeric proteins and processing mutants by the exchange and deletion of genomic exons.

S. Liebhaber, N. Cooke, J. Ray, 1986, The Journal of biological chemistry.

Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo.

B. Hollis, Lee A. Zella, N. Cooke, 2008, Endocrinology.

DNase I Hypersensitive Site II of the Human Growth Hormone Locus Control Region Mediates an Essential and Distinct Long-range Enhancer Function*

S. Liebhaber, Y. Ho, N. Cooke, 2012, The Journal of Biological Chemistry.

Inhibition of parathyroid hormone-induced fetal rat bone resorption in vitro by nerve growth factor

S. Teitelbaum, N. Cooke, A. Kahn, 1978, Calcified Tissue Research.