Hai-hong Shen

发表

Detecting RNA-Protein Interaction Using End-Labeled Biotinylated RNA Oligonucleotides and Immunoblotting.

Xuexiu Zheng, Sunghee Cho, H. Moon, 2016, Methods in molecular biology.

Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene.

Michael R Green, Michael R. Green, Giuseppe Biamonti, 2005, Molecular cell.

SR proteins regulate V6 exon splicing of CD44 pre-mRNA

Darren R. Williams, Xuexiu Zheng, H. Moon, 2016, BMB reports.

Regulation of Survival Motor Neuron Gene Expression by Calcium Signaling

Jae-Hyuk Jang, J. Ahn, Janghwan Kim, 2021, International journal of molecular sciences.

Improvement of spinal muscular atrophy via correction of the SMN2 splicing defect by Brucea javanica (L.) Merr. extract and Bruceine D.

S. Han, Janghwan Kim, Sungchan Cho, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Some leopards can change their spots: potential repositioning of stem cell reprogramming compounds as anti-cancer agents

Darren R. Williams, Hai-hong Shen, D. Jung, 2016, Cell Biology and Toxicology.

5‐Nitro‐5′hydroxy‐indirubin‐3′oxime Is a Novel Inducer of Somatic Cell Transdifferentiation

Darren R. Williams, Yong‐Chul Kim, Young-Jin Hong, 2014, Archiv der Pharmazie.

Apoptosis in Living Animals Is Assisted by Scavenger Cells and Thus May Not Mainly Go through the Cytochrome C-Caspase Pathway

A. Stojadinovic, N. Xu, D. Liao, 2013, Journal of Cancer.

Identification of Regulatory-RNAs for Alternative Splicing of Ron Proto-Oncogene

Darren R. Williams, Xuexiu Zheng, Tiing Jen Loh, 2015, Journal of Cancer.

Structural and biochemical insights into inhibition of human primase by citrate.

S. Eom, Jimin Wang, Hai-hong Shen, 2018, Biochemical and biophysical research communications.

Genome-Wide Characterisation of Gene Expression in Rice Leaf Blades at 25°C and 30°C

Lei Wang, Hai-hong Shen, Jianhua Zhou, 2014, TheScientificWorldJournal.

Predominant expression of exon 7 skipped SMN mRNAs in lung based on analysis of transcriptome sequencing datasets

Xiaoming Yang, Xuexiu Zheng, Hai-hong Shen, 2014, Neurological Sciences.

Isoforms of wild type proteins often appear as low molecular weight bands on SDS‐PAGE

Siqi Liu, N. Xu, Lucas Zellmer, 2014, Biotechnology journal.

Widespread Alternative Splicing Changes in Metastatic Cells.

C. Ghigna, Xiang-Dong Fu, Hai-Ri Li, 2021 .

A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model.

Ye Seul Son, Hyun-soo Cho, Jung-Hwa Oh, 2019, Stem cells and development.

Activation of Cryptic 3′ Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping

Xuexiu Zheng, H. Jang, Hai-hong Shen, 2019, Cells.

Irf3 Polymorphism Alters Induction of Interferon Beta in Response to Listeria monocytogenes Infection

Michael R. Green, Hai-hong Shen, O. Garifulin, 2007, PLoS genetics.

Irf 3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection

Michael R. Green, Hai-hong Shen, O. Garifulin, 2017 .

Global Alternative Splicing Defects in Human Breast Cancer Cells

C. Shao, C. Ghigna, Xiang-Dong Fu, 2021, Cancers.

Effects of PTCs on nonsense-mediated mRNA decay are dependent on PTC location.

Darren R. Williams, Xuexiu Zheng, Tiing Jen Loh, 2017, Oncology letters.

Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m6A Methylation of RNA in Acute Myeloid Leukemia Cells

Yong‐Chul Kim, M. Jin, Hai-hong Shen, 2022, Pharmaceuticals.

Opposite Roles of Tra2β and SRSF9 in the v10 Exon Splicing of CD44

C. Ghigna, Xuexiu Zheng, Hai-hong Shen, 2020, Cancers.

hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3′ Splice Sites

Xuexiu Zheng, Hai-hong Shen, Yongchao Liu, 2020, Cells.

Chimeric RNAs as potential biomarkers for tumor diagnosis.

Xuexiu Zheng, Hai-hong Shen, Jianhua Zhou, 2012, BMB reports.

Binding of SRSF4 to a novel enhancer modulates splicing of exon 6 of Fas pre-mRNA.

Xuexiu Zheng, H. Jang, Hai-hong Shen, 2018, Biochemical and biophysical research communications.

Suppression of 5' splice-sites through multiple exonic motifs by hnRNP L.

Xuexiu Zheng, Tiing Jen Loh, H. Jang, 2017, Biochimica et biophysica acta. Gene regulatory mechanisms.

CD44 alternative splicing and hnRNP A1 expression are associated with the metastasis of breast cancer.

Darren R. Williams, Yong Liu, D. Liao, 2015, Oncology reports.

3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons

D. Liao, Xuexiu Zheng, Sunghee Cho, 2014, TheScientificWorldJournal.

Exon 9 skipping of apoptotic caspase-2 pre-mRNA is promoted by SRSF3 through interaction with exon 8.

Michael R. Green, D. H. Kim, Z. Sheng, 2014, Biochimica et biophysica acta.

RS domains contact splicing signals and promote splicing by a common mechanism in yeast through humans.

Michael R. Green, Hai-hong Shen, Michael R. Green, 2006, Genes & development.

hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene

Z. Sheng, Y. Jun, Xuexiu Zheng, 2013, Apoptosis.

hnRNP M facilitates exon 7 inclusion of SMN2 pre-mRNA in spinal muscular atrophy by targeting an enhancer on exon 7.

H. Choy, Sungchan Cho, Xuexiu Zheng, 2014, Biochimica et biophysica acta.

A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly.

Michael R Green, Michael R. Green, Hai-hong Shen, 2004, Molecular cell.

Arginine-serine-rich domains bound at splicing enhancers contact the branchpoint to promote prespliceosome assembly.

Michael R. Green, Hai-hong Shen, J. Kan, 2004, Molecular cell.

Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells

C. Shao, C. Ghigna, Xiang-Dong Fu, 2021, Cells.

SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon

Darren R. Williams, C. Ghigna, Xuexiu Zheng, 2021, Cells.

SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion

Dong-Eun Kim, Sungchan Cho, Xuexiu Zheng, 2017, BMB reports.

SRSF2 promotes splicing and transcription of exon 11 included isoform in Ron proto-oncogene.

Michael R. Green, C. Ghigna, G. Biamonti, 2014, Biochimica et biophysica acta.

A novel indirubin derivative that increases somatic cell plasticity and inhibits tumorigenicity.

Darren R. Williams, Jeong-min Lee, Yong‐Chul Kim, 2019, Bioorganic & medicinal chemistry.

SRSF6 Regulates the Alternative Splicing of the Apoptotic Fas Gene by Targeting a Novel RNA Sequence

Sunjae Lee, Xuexiu Zheng, H. Jang, 2022, Cancers.

RS domain–splicing signal interactions in splicing of U12-type and U2-type introns

Michael R. Green, Hai-hong Shen, Michael R. Green, 2007, Nature Structural &Molecular Biology.

Michael R. Green, Stephan Luecke, Xuexiu Zheng, 2010, Genes & development.

Possible Formation of Mitochondrial-RNA Containing Chimeric or Trimeric RNA Implies a Post-Transcriptional and Post-Splicing Mechanism for RNA Fusion

G. Chirn, Wei Yang, D. Liao, 2013, PloS one.

U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing

Xuexiu Zheng, Hai-hong Shen, Yongchao Liu, 2020, Cells.

Splicing inhibition of U2AF65 leads to alternative exon skipping

T. Ohn, Xuexiu Zheng, Sunghee Cho, 2015, Proceedings of the National Academy of Sciences.

PSF contacts exon 7 of SMN2 pre-mRNA to promote exon 7 inclusion.

Michael R. Green, D. Liao, Xuexiu Zheng, 2014, Biochimica et biophysica acta.

Validation of trans-acting elements that promote exon 7 skipping of SMN2 in SMN2-GFP stable cell line.

Xiaoming Yang, Xuexiu Zheng, Sunghee Cho, 2012, Biochemical and biophysical research communications.

Identification of a novel cis-element that regulates alternative splicing of Bcl-x pre-mRNA.

Xuexiu Zheng, Sunghee Cho, Tiing Jen Loh, 2012, Biochemical and biophysical research communications.

Targeting RNA-splicing for SMA treatment

Xuexiu Zheng, Hai-hong Shen, Jianhua Zhou, 2012, Molecules and cells.

A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene

Michael R. Green, C. Ghigna, G. Biamonti, 2013, Oncology reports.

A single polypyrimidine tract binding protein (PTB) binding site mediates splicing inhibition at mouse IgM exons M1 and M2.

Michael R Green, Michael R. Green, Giuseppe Biamonti, 2004, RNA.

Solution Conformation and Thermodynamic Characteristics of RNA Binding by the Splicing Factor U2AF65*

Michael R. Green, Hai-hong Shen, J. Jenkins, 2008, Journal of Biological Chemistry.

Structural basis for polypyrimidine tract recognition by the essential pre-mRNA splicing factor U2AF65.

Michael R Green, Michael R. Green, Hai-hong Shen, 2006, Molecular cell.

A rapid and high content assay that measures cyto-ID-stained autophagic compartments and estimates autophagy flux with potential clinical applications

Deborah F. Kelly, Yanping Liang, Z. Sheng, 2015, Autophagy.

Delineation of the role of glycosylation in the cytotoxic properties of quercetin using novel assays in living vertebrates.

Darren R. Williams, Soon-Ho Yim, B. Shin, 2014, Journal of natural products.

Identification of novel splicing variants from RON proto-oncogene pre-mRNA.

Xiaoming Yang, Xuexiu Zheng, Sunghee Cho, 2012, Oncology reports.

Two Site Contact of Elongating Transcripts to Phage T7 RNA Polymerase at C-terminal Regions*

Hai-hong Shen, C. Kang, 2000, The Journal of Biological Chemistry.

UAP56- a key player with surprisingly diverse roles in pre-mRNA splicing and nuclear export.

Hai-hong Shen, 2009, BMB reports.

Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome.

Michael R. Green, Xuexiu Zheng, Hai-hong Shen, 2008, Genes & development.

CRISPR as a strong gene editing tool

Xuexiu Zheng, Tiing Jen Loh, Hai-hong Shen, 2017, BMB reports.

hnRNP L inhibits CD44 V10 exon splicing through interacting with its upstream intron.

Darren R. Williams, C. Ghigna, G. Biamonti, 2015, Biochimica et biophysica acta.

hnRNP A1 contacts exon 5 to promote exon 6 inclusion of apoptotic Fas gene

Michael R. Green, Z. Sheng, Y. Jun, 2013, Apoptosis.

Some leopards can change their spots: potential repositioning of stem cell reprogramming compounds as anti-cancer agents

Darren R. Williams, Hai-hong Shen, D. Jung, 2016, Cell Biology and Toxicology.

SC35 promotes splicing of the C5-V6-C6 isoform of CD44 pre-mRNA

Michael R. Green, D. H. Kim, Seong-Eui Hong, 2013, Oncology reports.

Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans

Hai-hong Shen, Sangho Lee, Hyun Sung, 2011, Molecules and cells.

Differential physiological roles of ESCRT complexes in Caenorhabditis elegans

J. Ahnn, Hai-hong Shen, Sangho Lee, 2011, Molecules and cells.

Targeting RNA-splicing for SMA treatment

Xuexiu Zheng, Hai-hong Shen, Jianhua Zhou, 2012, Molecules and cells.

Differential physiological roles of ESCRT complexes in Caenorhabditis elegans

J. Ahnn, Hai-hong Shen, Sangho Lee, 2011, Molecules and cells.

Stepwise walking and cross-linking of RNA with elongating T7 RNA polymerase.

Hai-hong Shen, C. Kang, Younghee Sohn, 2003, Methods in enzymology.

5‐Nitro‐5′hydroxy‐indirubin‐3′oxime Is a Novel Inducer of Somatic Cell Transdifferentiation

Yong‐Chul Kim, Young-Jin Hong, Hai-hong Shen, 2014, Archiv der Pharmazie.