K. Breitkopf

发表

Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways.

S. Dooley, C. Borner, Reinhart Heinrich, 2006, Systems biology.

Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

S. Dooley, R. Gebhardt, E. Ueberham, 2008, Gastroenterology.

TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I.

S. Dooley, Nadja M Meindl-Beinker, E. Ueberham, 2009, Journal of hepatology.

Transforming growth factor-β induces nerve growth factor expression in pancreatic stellate cells by activation of the ALK-5 pathway

S. Dooley, R. Jaster, B. Fitzner, 2009, Growth factors.

Thrombospondin 1 acts as a strong promoter of transforming growth factor β effects via two distinct mechanisms in hepatic stellate cells

S. Dooley, A. Gressner, L. Wickert, 2005, Gut.

Current experimental perspectives on the clinical progression of alcoholic liver disease.

S. Dooley, S. Mueller, H. Weng, 2009, Alcoholism, clinical and experimental research.

Liver fibrogenesis due to cholestasis is associated with increased Smad7 expression and Smad3 signaling

S. Dooley, A. Gressner, R. Horch, 2006, Journal of cellular and molecular medicine.

Transdifferentiation-dependent expression of α-SMA in hepatic stellate cells does not involve TGF-β pathways leading to coinduction of collagen type I and thrombospondin-2

S. Dooley, A. Gressner, L. Wickert, 2005 .

Characterization of intracellular pathways leading to coinduction of thrombospondin-1 and TGF-β1 expression in rat hepatic stellate cells

A. Gressner, K. Breitkopf, I. Sawitza, 2005, Growth factors.

TGF-beta/Smad signaling in the injured liver.

S. Dooley, P. Godoy, K. Breitkopf, 2006, Zeitschrift fur Gastroenterologie.

TGF-β/Smad Signaling in the Injured Liver

S. Dooley, P. Godoy, K. Breitkopf, 2006 .

Anti‐TGF‐β Strategies for the Treatment of Chronic Liver Disease

S. Dooley, K. Breitkopf, E. Wiercinska, 2004 .

Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors α and β in activated rat hepatic stellate cells (HSC)

A. Gressner, J. Floege, L. Wickert, 2005 .

Expression and matrix deposition of latent transforming growth factor β binding proteins in normal and fibrotic rat liver and transdifferentiating hepatic stellate cells in culture

A. Gressner, K. Breitkopf, C. Tag, 2001, Hepatology.

Id1 is a critical mediator in TGF‐β–induced transdifferentiation of rat hepatic stellate cells

S. Dooley, A. Gressner, L. Wickert, 2006, Hepatology.

PDGF-BB Induces Expression of LTBP-1 but not TGF-β1 in a Rat Cirrhotic Fat Storing Cell Line

A. Gressner, J. Keski‐Oja, K. Breitkopf, 2003, Growth factors.

Expression of cytosolic and membrane associated tissue transglutaminase in rat hepatic stellate cells and its upregulation during transdifferentiation to myofibroblasts in culture.

A. Gressner, C. Schnabel, K. Breitkopf, 2004, Hepatology research : the official journal of the Japan Society of Hepatology.

Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC).

A. Gressner, J. Floege, L. Wickert, 2005, Cytokine.

Roles of TGF-beta in hepatic fibrosis.

S. Dooley, A. Gressner, R. Weiskirchen, 2002, Frontiers in bioscience : a journal and virtual library.

Anti-TGF-beta strategies for the treatment of chronic liver disease.

S. Dooley, K. Breitkopf, E. Wiercinska, 2005, Alcoholism, clinical and experimental research.

Tissue Inhibitor of Matrix Metalloproteinase-2 Regulates Matrix Metalloproteinase-2 Activation by Modulation of Membrane-type 1 Matrix Metalloproteinase Activity in High and Low Invasive Melanoma Cell Lines*

T. Krieg, C. Klein, P. Kurschat, 1999, The Journal of Biological Chemistry.

Profibrogenic transforming growth factor‐β/activin receptor–like kinase 5 signaling via connective tissue growth factor expression in hepatocytes

S. Dooley, R. Gebhardt, U. Ueberham, 2007, Hepatology.

Glucocorticoids decrease the bioavailability of TGF-β which leads to a reduced TGF-β signaling in hepatic stellate cells

S. Dooley, A. Gressner, L. Wickert, 2004 .

Smad7 prevents activation of hepatic stellate cells and liver fibrosis in rats.

S. Dooley, A. Gressner, P. ten Dijke, 2003, Gastroenterology.

SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression.

Michael Boutros, Matthias W. Hentze, Martina U. Muckenthaler, 2010, Blood.

TGF-β/Smad-signaling in liver cells: Target genes and inhibitors of two parallel pathways

S. Dooley, H. Weng, K. Breitkopf, 2006 .

Extraction of the Plasticizers Diethylhexylphthalate and Polyadipate From Polyvinylchloride Nasogastric Tubes Through Gastric Juice and Feeding Solution

J. Brade, K. Breitkopf, U. Subotic, 2007, Journal of pediatric gastroenterology and nutrition.

Transdifferentiation-dependent expression of alpha-SMA in hepatic stellate cells does not involve TGF-beta pathways leading to coinduction of collagen type I and thrombospondin-2.

S. Dooley, A. Gressner, L. Wickert, 2005, Matrix biology : journal of the International Society for Matrix Biology.

Divergence of TGFβ signaling in activated hepatic stellate cells downstream from Smad2 phosphorylation

S. Dooley, A. Gressner, Chunfang Gao, 2002 .

279 BONE MORPHOGENETIC PROTEIN (BMP)-9: A NEW MEMBER OF THE TGF-β SUPERFAMILY WHICH IS SECRETED BY ACTIVATED HEPATIC STELLATE CELLS

S. Dooley, P. Dijke, K. Breitkopf, 2009 .

The effect of the calcium‐antagonist nitrendipine on intracellular calcium concentration in endothelial cells

W. Klaus, S. Dhein, K. Breitkopf, 1996, British journal of pharmacology.

Glucocorticoids decrease the bioavailability of TGF-beta which leads to a reduced TGF-beta signaling in hepatic stellate cells.

S. Dooley, A. Gressner, L. Wickert, 2004, Biochemical and Biophysical Research Communications - BBRC.

Selective loss of PMA-stimulated expression of matrix metalloproteinase 1 in HaCaT keratinocytes is correlated with the inability to induce mitogen-activated protein family kinases.

T. Krieg, C. Mauch, K. Breitkopf, 1999, The Biochemical journal.