H. Tanaka

发表

Kitasatosporia, a new genus of the order Actinomycetales.

S. Ōmura, Y. Takahashi, Y. Iwai, 1982, The Journal of antibiotics.

Cloning of large DNA fragments, which hybridize with actinorhodin biosynthesis genes, from kalafungin and nanaomycin A methyl ester producers and identification of genes for kalafungin biosynthesis of the kalafungin producer.

H. Ikeda, S. Ōmura, D. Hopwood, 1991, The Journal of antibiotics.

Phthoxazolin A, a specific inhibitor of cellulose biosynthesis from microbial origin. II. Isolation, physico-chemical properties, and structural elucidation.

S. Ōmura, Y. Tanaka, K. Shiomi, 1993, The Journal of antibiotics.

Phthoxazolin A, a specific inhibitor of cellulose biosynthesis from microbial origin. I. Discovery, taxonomy of producing microorganism, fermentation, and biological activity.

S. Ōmura, Y. Takahashi, Y. Tanaka, 1993, The Journal of antibiotics.

Neuronal differentiation of neuro 2a cells by inhibitors of cell cycle progression, trichostatin A and butyrolactone I.

S. Ōmura, M. Yoshida, S. Horinouchi, 1999, Biochemical and biophysical research communications.

The mode of action of cervinomycin in Staphylococcus aureus.

S. Ōmura, K. Kawakita, H. Suzuki, 1989, The Journal of antibiotics.

Studies on WF-3161, a new antitumor antibiotic.

K. Nakahara, H. Imanaka, H. Tanaka, 1983, The Journal of antibiotics.

Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. II. Structure elucidation and total synthesis.

S. Ōmura, Y. Iwai, K. Shiomi, 1996, The Journal of antibiotics.

Production of nanaomycin and other antibiotics by phosphate-depressed fermentation using phosphate-trapping agents.

S. Ōmura, Y. Tanaka, R. Masuma, 1986, The Journal of antibiotics.

Thiotetromycin, a new antibiotic. Taxonomy, production, isolation, and physicochemical and biological properties.

S. Ōmura, Y. Takahashi, A. Nakagawa, 1983, The Journal of antibiotics.

Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis

H. Ikeda, H. Kotaki, S. Ōmura, 1988, Antimicrobial Agents and Chemotherapy.

Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics.

S. Ōmura, H. Arai, S. Okuda, 1992, The Journal of antibiotics.

The mode of action of a novel 18-membered macrolide, virustomycin A (AM-2604 A), on Trichomonas foetus.

S. Ōmura, H. Tanaka, K. Otoguro, 1983, The Journal of antibiotics.

Phosalacine, a new herbicidal antibiotic containing phosphinothricin. Fermentation, isolation, biological activity and mechanism of action.

S. Ōmura, H. Hanaki, R. Oiwa, 1984, The Journal of antibiotics.

The impact of lesion length and vessel size on outcomes after sirolimus-eluting stent implantation for in-stent restenosis

K. Kadota, Y. Fuku, S. Otsuru, 2007, Heart.

Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells.

S. Ōmura, H. Tanaka, K. Otoguro, 1991, The Journal of antibiotics.

Screening for new nematocidal substances of microbial origin by a new method using the pine wood nematode.

S. Ōmura, Y. Li, Y. Iwai, 1988, The Journal of antibiotics.

Screening for new antitrichomonal substances of microbial origin and antitrichomonal activity of trichostatin A.

S. Ōmura, R. Oiwa, Y. Iwai, 1988, The Journal of antibiotics.

Funalenone, a novel collagenase inhibitor produced by Aspergillus niger.

S. Ōmura, H. Yamada, R. Masuma, 1999, The Journal of antibiotics.

Madindoline, a novel inhibitor of IL-6 activity from Streptomyces sp. K93-0711. I. Taxonomy, fermentation, isolation and biological activities.

S. Ōmura, M. Hayashi, Y. Takahashi, 1996, The Journal of antibiotics.

Analysis of closed loop identification based on the Riccati difference equation and joint input-output method

H. Tanaka, S. Omura, 2022 .

Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT). Part 1: identification and structure-activity relationships of a novel series of substituted N-alkyl-N-biphenylylmethyl-N'-arylureas.

H. Tanaka, A. Tanaka, H. Takasugi, 1998, Bioorganic & medicinal chemistry.

Structure-specific inhibition of cholesteryl ester transfer protein by azaphilones.

S. Ōmura, H. Arai, N. Tabata, 1999, The Journal of antibiotics.

Neuronal differentiation of Neuro 2a cells by lactacystin and its partial inhibition by the protein phosphatase inhibitors calyculin A and okadaic acid.

S. Ōmura, H. Tanaka, J. Inokoshi, 1995, Biochemical and biophysical research communications.

Structure of a new macrocyclic antibiotic

T. Taga, H. Tanaka, T. Goto, 1987 .

Studies on bacterial cell wall inhibitors. X. Properties of phosph-N-acetylmuramoyl-pentapeptide-transferase in peptidoglycan synthesis of Bacillus megaterium and its inhibition by amphomycin.

S. Ōmura, R. Oiwa, H. Tanaka, 1982, The Journal of antibiotics.

Studies on bacterial cell wall inhibitors. VIII. Mode of action of a new antibiotic, azureomycin B, in Bacillus cereus T.

S. Ōmura, Y. Tanaka, R. Oiwa, 1979, The Journal of antibiotics.

Studies on bacterial cell wall inhibitors. II. Inhibition of peptidoglycan synthesis in vivo and in vitro by amphomycin.

S. Ōmura, S. Shimizu, T. Oka, 1977, Biochimica et biophysica acta.

Amidepsine E, an inhibitor of diacylglycerol acyltransferase produced by Humicola sp. FO-5969.

S. Ōmura, T. Kobayashi, N. Tabata, 1996, The Journal of antibiotics.

Biosynthesis of vineomycins A1 and B2.

S. Ōmura, K. Kakinuma, N. Ikekawa, 1982, The Journal of antibiotics.

Irumamycin, a new antibiotic active against phytopathogenic fungi.

S. Ōmura, Y. Tanaka, A. Nakagawa, 1982, The Journal of antibiotics.

The structure of vineomycin B2.

S. Ōmura, K. Kakinuma, N. Ikekawa, 1981, The Journal of antibiotics.

A new antibiotic, setomimycin, produced by a strain of Streptomyces.

S. Ōmura, Y. Takahashi, R. Masuma, 1978, The Journal of antibiotics.

New antitumor antibiotics, OS-4742 A1, A2, B1 and B2 produced by a strain of Streptomyces.

S. Ōmura, R. Oiwa, R. Masuma, 1977, The Journal of antibiotics.

A new antibiotic,, asukamycin, produced by Streptomyces.

S. Ōmura, Y. Takahashi, R. Oiwa, 1976, The Journal of antibiotics.

A new antitumor complex, WF-1360, WF-1360A, B, C, D, E and F.

M. Okuhara, H. Tanaka, M. Kohsaka, 1986, The Journal of antibiotics.

Isolation and characterization of covalently closed circular DNA associated with chromosomal and membrane fraction from Streptomyces ambofaciens.

H. Ikeda, S. Ōmura, H. Tanaka, 1982, The Journal of antibiotics.

Extraction and characterization of plasmids from macrolide antibiotic-producing streptomycetes.

H. Ikeda, S. Ōmura, H. Tanaka, 1981, The Journal of antibiotics.

Stimulation of leucomycin production by magnesium phosphate and its relevance to nitrogen catabolite regulation

S. Ōmura, Y. Tanaka, Y. Iwai, 1980, Antimicrobial Agents and Chemotherapy.

Studies on WF-5239, a new potent platelet aggregation inhibitor.

H. Imanaka, H. Tanaka, M. Kohsaka, 1984, The Journal of antibiotics.

Adecypenol, a unique adenosine deaminase inhibitor containing homopurine and cyclopentene rings.

S. Ōmura, D. Imamura, H. Kuga, 1986, The Journal of antibiotics.

Structure-activity relationships of lactacystin, the first non-protein neurotrophic factor.

S. Ōmura, H. Tanaka, T. Nagamitsu, 1995, The Journal of antibiotics.

The neuritogenesis inducer lactacystin arrests cell cycle at both G0/G1 and G2 phases in neuro 2a cells.

S. Ōmura, M. Hayashi, H. Tanaka, 1995, The Journal of antibiotics.

Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. I. Taxonomy, fermentation, isolation, and physico-chemical properties and biological activities.

H. B. Woodruff, H. Ikeda, S. Ōmura, 1997, The Journal of antibiotics.

Isochromophilones I and II, novel inhibitors against gp120-CD4 binding produced by Penicillium multicolor FO-2338. I. Screening, taxonomy, fermentation, isolation and biological activity.

H. Ikeda, S. Ōmura, R. Masuma, 1995, The Journal of antibiotics.

Isochromophilones I and II, novel inhibitors against gp120-CD4 binding from Penicillium sp.

H. Ikeda, S. Ōmura, R. Masuma, 1993, The Journal of antibiotics.

Nanaomycins, new antibiotics produced by a strain of Streptomyces. III. A new component, nanaomycin C, and biological activities of nanaomycin derivatives.

H. Tanaka, Haruo Tanaka, T. Nagai, 1975, The Journal of antibiotics.

Nanaomycins, new antibiotics produced by a strain of Streptomyces. I. Taxonomy, isolation, characterization and biological properties.

S. Ōmura, R. Oiwa, H. Tanaka, 1975, The Journal of antibiotics.

Amphomycin inhibits phospho-N-acetylmuramyl-pentapeptide translocase in peptidoglycan synthesis of Bacillus.

S. Ōmura, R. Oiwa, H. Tanaka, 1979, Biochemical and biophysical research communications.

Synthesis of doxorubicin-cyclodextrin conjugates.

R. Okamoto, H. Tanaka, T. Yoshioka, 1994, The Journal of antibiotics.

Studies on bacterial cell wall inhibitors. VI. Screening method for the specific inhibitors of peptidoglycan synthesis.

S. Ōmura, Y. Takahashi, R. Oiwa, 1979, Journal of antibiotics (Tokyo. 1968).

Chloropeptins, new anti-HIV antibiotics inhibiting gp120-CD4 binding from Streptomyces sp. II. Structure elucidation of chloropeptin I.

S. Ōmura, H. Tanaka, T. Sunazuka, 1997, The Journal of antibiotics.

Antibiotic no. 5879, a new water-soluble antibiotic against gram-negative bacteria.

H. Tanaka, H. Otsuka, S. Miyamura, 1972, The Journal of antibiotics.

Letter: Nanaomycins A and B, new antibiotics produced by a strain of Streptomyces.

S. Ōmura, R. Oiwa, H. Tanaka, 1974, The Journal of antibiotics.

A new antitumor antibiotic product, demethylchartreusin. Isolation and biological activities.

H. Tanaka, K. Kon, Y. Aoyama, 1992, The Journal of antibiotics.

Pyripyropenes, novel ACAT inhibitors produced by Aspergillus fumigatus. IV. Structure elucidation of pyripyropenes M to R.

S. Ōmura, N. Tabata, H. Tomoda, 1996, The Journal of antibiotics.

M. Okuhara, H. Tanaka, H. Hatanaka, 1989, The Journal of antibiotics.

Studies on bacterial cell wall inhibitors. VII. Azureomycins A and B, new antibiotics produced by Pseudonocardia azurea nov. sp. Taxonomy of the producing organism, isolation, characterization and biological properties.

S. Ōmura, K. Matsuyama, Y. Takahashi, 1979, The Journal of antibiotics.

Studies on new dehydropeptidase inhibitors. II. Structural elucidation and synthesis of WS1358A1 and B1.

H. Tanaka, M. Hashimoto, S. Hashimoto, 1990, The Journal of antibiotics.

OM-173, new nanaomycin-type antibiotics produced by a strain of Streptomyces. Taxonomy, production, isolation and biological properties.

S. Ōmura, Y. Takahashi, Y. Iwai, 1983, The Journal of antibiotics.

Structure of nanaomycin E, a new nanaomycin.

S. Ōmura, H. Tanaka, M. Kasai, 1979, The Journal of antibiotics.

Nanomycins, new antibiotics produced by a strain of Streptomyces. II. Structure and biosynthesis.

S. Ōmura, H. Tanaka, T. Nagai, 1975, The Journal of antibiotics.

Studies on a new immunoactive peptide, FK-156. III. Structure elucidation.

K. Nakahara, H. Imanaka, H. Tanaka, 1982, The Journal of antibiotics.

New brominated and halogen-less derivatives and structure-activity relationship of azaphilones inhibiting gp120-CD4 binding.

S. Ōmura, R. Masuma, H. Tanaka, 1998, The Journal of antibiotics.

Orally active cephalosporins. Part 3: synthesis, structure-activity relationships and oral absorption of novel C-3 heteroarylmethylthio cephalosporins.

H. Tanaka, Y. Matsumoto, S. Matsumoto, 2001, Bioorganic & medicinal chemistry.

Oxetin, a new antimetabolite from an actinomycete. Fermentation, isolation, structure and biological activity.

S. Ōmura, A. Furusaki, N. Imamura, 1984, The Journal of antibiotics.

Chloropeptins I and II, novel inhibitors against gp120-CD4 binding from Streptomyces sp.

H. B. Woodruff, H. Ikeda, S. Ōmura, 1994, The Journal of antibiotics.

Structures of jietacines: unique alpha,beta-unsaturated azoxy antibiotics.

S. Ōmura, N. Imamura, H. Kuga, 1989, The Journal of antibiotics.

Jietacins A and B, new nematocidal antibiotics from a Streptomyces sp. Taxonomy, isolation, and physico-chemical and biological properties.

S. Ōmura, Y. Takahashi, Y. Tanaka, 1987, The Journal of antibiotics.

FK463, a novel water-soluble echinocandin lipopeptide: synthesis and antifungal activity.

A. Yamada, H. Tanaka, H. Takasugi, 1999, The Journal of antibiotics.

Application of the random amplified polymorphic DNA using the polymerase chain reaction for efficient elimination of duplicate strains in microbial screening. III. Bacteria.

H. Tanaka, T. Okuda, T. Okuda, 1994, The Journal of antibiotics.

Saturated fatty acid-starved cells of Saccharomyces cerevisiae grown in the presence of cerulenin and oleic acid.

S. Ōmura, H. Tanaka, K. Otoguro, 1981, Journal of biochemistry.

Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds.

S. Ōmura, H. Tanaka, H. Matsubara, 1983, The Journal of antibiotics.

Studies of tylosin derivatives effective against macrolide-resistant strains: synthesis and structure-activity relationships.

T. Takeuchi, M. Hamada, H. Umezawa, 1982, The Journal of antibiotics.

Chemical modification of anthracycline antibiotics. I. Demethoxycarbonylation, 10-epimerization and 4-o-methylation of aclacinomycin A.

T. Oki, H. Tanaka, T. Yoshioka, 1980, The Journal of antibiotics.

Dechlorogeodin and its new dihydro derivatives, fungal metabolites with herbicidal activity.

S. Ōmura, Y. Tanaka, R. Masuma, 1996, The Journal of antibiotics.

Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. I. Producing strain, fermentation, isolation, and biological activities.

S. Ōmura, R. Masuma, Y. Iwai, 1996, The Journal of antibiotics.

FR65814, a novel immunosuppressant isolated from a Penicillium strain. Taxonomy, fermentation, isolation, physico-chemical and biological characteristics and structure assignment.

M. Okuhara, H. Tanaka, H. Hatanaka, 1988, The Journal of antibiotics.

Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis.

M. Okuhara, H. Tanaka, H. Hatanaka, 1987, Transplantation proceedings.

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination.

H. Tanaka, Hirokazu Tanaka, N Shigematsu, 1994, The Journal of antibiotics.

New anticoccidial antibiotics, WS-5995 A and B. I. Isolation and characterization.

H. Imanaka, H. Tanaka, M. Kohsaka, 1980, The Journal of antibiotics.

Bioconversion and biosynthesis of nanaomycins using cerulenin, a specific inhibitor of fatty acid and polyketide biosyntheses.

S. Ōmura, H. Tanaka, C. Kitao, 1980, The Journal of antibiotics.

New inhibitors of melanogenesis, OH-3984 K1 and K2. I. Taxonomy, fermentation, isolation and biological characteristics.

S. Ōmura, G. Imokawa, M. Hayashi, 1993, The Journal of antibiotics.

New inhibitors of melanogenesis, OH-3984 K1 and K2. II. Physico-chemical properties and structural elucidation.

S. Ōmura, G. Imokawa, M. Hayashi, 1993, The Journal of antibiotics.

New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465.

H. Tanaka, H. Nakajima, H. Terano, 1997, The Journal of antibiotics.

Studies on bacterial cell wall inhibitors. III. 3-amino-3-deoxy-D-glucose, an inhibitor of bacterial cell wall synthesis.

S. Ōmura, S. Shimizu, R. Oiwa, 1977, Biochimica et biophysica acta.

Studies on WB-3559 A, B, C and D, new potent fibrinolytic agents. II. Structure elucidation and synthesis.

H. Imanaka, H. Tanaka, M. Kohsaka, 1985, The Journal of antibiotics.

The mode of action of nanaomycins D and A on a gram-negative marine bacterium Vibrio alginolyticus.

S. Ōmura, H. Tanaka, M. Hayashi, 1982, The Journal of antibiotics.

Biosynthesis of nanaomycin. III. Nanaomycin A formation from nanaomycin D by nanaomycin D reductase via a hydroquinone.

S. Ōmura, H. Tanaka, S. Minami-Kakinuma, 1982, Journal of antibiotics (Tokyo. 1968).

The mode of action of nanaomycin A in Gram-positive bacteria.

S. Ōmura, M. Morimoto, H. Tanaka, 1980, The Journal of antibiotics.

Adechlorin, a new adenosine deaminase inhibitor containing chlorine production, isolation and properties.

S. Ōmura, Y. Takahashi, N. Imamura, 1985, The Journal of antibiotics.

Andrastin D, novel protein farnesyltransferase inhibitor produced by Penicillium sp. FO-3929.

S. Ōmura, Y. Iwai, K. Shiomi, 1996, The Journal of antibiotics.

Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. II. Structure elucidation and biosynthesis.

S. Ōmura, Y. Iwai, K. Shiomi, 1996, The Journal of antibiotics.

Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 2. Identification and structure-activity relationships of a novel series of N-alkyl-N-(heteroaryl-substituted benzyl)-N'-arylureas.

H. Tanaka, A. Tanaka, H. Takasugi, 1998, Journal of medicinal chemistry.

Studies on new antiplatelet agents, WS-30581 A and B.

H. Imanaka, H. Tanaka, M. Kohsaka, 1984, The Journal of antibiotics.

Structure and synthesis of WB-3559 A, B, C and D, new fibrinolytic agents isolated from Flavobacterium sp.

H. Imanaka, H. Tanaka, M. Kohsaka, 1985, Chemical & pharmaceutical bulletin.

Biosynthesis of nanaomycin. II. Purification and properties of nanaomycin D reductase involved in the formation of nanaomycin A from nanaomycin D1.

S. Ōmura, H. Tanaka, S. Minami, 1981, Journal of biochemistry.

Biosynthesis of nanaomycin: syntheses of nanaomycin E from nanaomycin A and of nanaomycin B from nanaomycin E in a cell-free system.

S. Ōmura, H. Tanaka, S. Minami, 1981, Journal of biochemistry.

Chlovalicin, a new cytocidal antibiotic produced by Sporothrix sp. FO-4649. I. Taxonomy, fermentation, isolation and biological activities.

S. Ōmura, M. Hayashi, S. Takamatsu, 1996, The Journal of antibiotics.

Selective production of specific components of avermectins in Streptomyces avermitilis.

H. Ikeda, S. Ōmura, H. Tanaka, 1991, The Journal of antibiotics.

Synthesis of 1233A analogs and their inhibitory activity against hydroxymethylglutaryl coenzyme A synthase.

S. Ōmura, H. Tomoda, H. Tanaka, 1992, The Journal of antibiotics.

Revised Nomenclature of Kitasatosporia setalba

S. Ōmura, Yoko Takahashi, Y. Iwai, 1985 .

Effects of phytosterols on anti-complementary activity.

S. Ōmura, J. Cyong, H. Kiyohara, 1987, Chemical & pharmaceutical bulletin.

Synthesis, X-ray crystal structure, and biological activity of FR186054, a novel, potent, orally active inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) bearing a pyrazole ring.

T. Kinoshita, H. Tanaka, A. Tanaka, 1998, Bioorganic & medicinal chemistry letters.

Potentiation of cytotoxicity and antitumor activity of adenosine analogs by the adenosine deaminase inhibitor adecypenol.

S. Ōmura, K. Komiyama, H. Tanaka, 1989, The Journal of antibiotics.

A simple screening system for anti-HIV drugs: syncytium formation assay using T-cell line tropic and macrophage tropic HIV env expressing cell lines--establishment and validation.

S. Ōmura, H. Tanaka, J. Inokoshi, 2001, The Journal of antibiotics.

Actinohivin, a novel anti-HIV protein from an actinomycete that inhibits syncytium formation: isolation, characterization, and biological activities.

S. Ōmura, M. Oheda, Y. Takahashi, 2001, Biochemical and biophysical research communications.

FR-900520 and FR-900523, novel immunosuppressants isolated from a Streptomyces. II. Fermentation, isolation and physico-chemical and biological characteristics.

M. Okuhara, H. Tanaka, N. Inamura, 1988, The Journal of antibiotics.

A new antitumor antibiotic, FR900840. II. Structural elucidation of FR900840.

H. Nakada, H. Tanaka, T. Goto, 1989, The Journal of antibiotics.

Izupeptins A and B, new glycopeptide antibiotics produced by an actinomycete.

S. Ōmura, Y. Takahashi, Y. Tanaka, 1986, The Journal of antibiotics.

Screening for new antifolates of microbial origin and a new antifolate AM-8402.

S. Ōmura, H. Tanaka, K. Kimura, 1985, The Journal of antibiotics.

Stimulation of the production of macrolide antibiotics by magnesium phosphate and related insoluble materials.

S. Ōmura, Y. Takahashi, Y. Tanaka, 1980, Journal of antibiotics (Tokyo. 1968).

Chemical modification of spiramycins. IV. Synthesis and in vitro and in vivo activities of 3'',4''-diacylates and 3,3'',4''-triacylates of spriamycin I.

S. Ōmura, H. Sano, H. Tanaka, 1984, The Journal of antibiotics.

Chemical modification of spiramycins. III. Synthesis and antibacterial activities of 4''-sulfonates and 4''-alkylethers of spiramycin I.

S. Ōmura, H. Sano, H. Tanaka, 1984, The Journal of antibiotics.

Synthesis and biological activity of analogues of diazaquinomycin A, a new thymidylate synthase inhibitor.

S. Ōmura, H. Tanaka, M. Murata, 1989, The Journal of antibiotics.

7-Hydro-8-methylpteroylglutamylglutamic acid, a new anti-folate from an actinomycete. Fermentation, isolation, structure and biological activity.

S. Ōmura, H. Tanaka, M. Murata, 1987, The Journal of antibiotics.

Diazaquinomycin A, a new antifolate antibiotic, inhibits thymidylate synthase.

S. Ōmura, H. Tanaka, T. Miyasaka, 1985, The Journal of antibiotics.

OM-704 A, a new antibiotic active against gram-positive bacteria produced by Streptomyces sp.

S. Ōmura, Y. Takahashi, A. Nakagawa, 1982, The Journal of antibiotics.

Madindolines, novel inhibitors of IL-6 activity from streptomyces sp. K93-0711. II. Physico-chemical properties and structural elucidation.

S. Ōmura, M. Hayashi, S. Takamatsu, 1997, Journal of antibiotics (Tokyo. 1968).

Madindolines, Novel Inhibitors of IL-6 Activity from Streptomyces sp. K93-0711. Part 2. Physico-Chemical Properties and Structural Elucidation.

S. Ōmura, S. Takamatsu, A. Enomoto, 1998 .

Chlovalicin, a new cytocidal antibiotic produced by Sporothrix sp. FO-4649. II. Physicochemical properties and structural elucidation.

S. Ōmura, M. Hayashi, S. Takamatsu, 1996, The Journal of antibiotics.

Molecular cloning of actinohivin, a novel anti-HIV protein from an actinomycete, and its expression in Escherichia coli.

S. Ōmura, H. Tanaka, J. Inokoshi, 2001, Biochemical and biophysical research communications.

Binding of [3H]tetrahydroleucomycin A3 to Escherichia coli ribosomes and the effect of 3"-O-acyl derivatives of leucomycins on the binding.

S. Ōmura, H. Tanaka, J. Inokoshi, 1982, The Journal of antibiotics.

Chemical modification of spiramycins. VI. Synthesis and antibacterial activities of 3,3''-di-O-acyl-4''-O-sulfonyl and 3,3''-di-O-acyl-4''-O-alkyl derivatives of spiramycin I.

S. Ōmura, H. Tanaka, T. Sunazuka, 1985, The Journal of antibiotics.

Chemical modification of tylosin: synthesis of amino derivatives at C-20 position of tylosin and demycarosyltylosin.

S. Ōmura, A. Nakagawa, H. Tanaka, 1983, The Journal of antibiotics.

Chemical modification of spiramycins. V. Synthesis and antibacterial activity of 3'- or 4''-de-N-methylspiramycin I and their N-substituted derivatives.

S. Ōmura, H. Sano, H. Tanaka, 1985, The Journal of antibiotics.

Isolation and Biological Activity•õ

S. Ōmura, H. Tanaka, J. Awaya, 2008 .

Interspecific protoplast fusion among macrolide-producing streptomycetes.

H. Ikeda, S. Ōmura, H. Tanaka, 1984, The Journal of antibiotics.

Genetic and biochemical features of spiramycin biosynthesis in Streptomyces ambofaciens--curing, protoplast regeneration and plasmid transfer.

H. Ikeda, S. Ōmura, H. Tanaka, 1982, The Journal of antibiotics.

Inhibition of gelatinolytic activity in tumor tissues by synthetic matrix metalloproteinase inhibitor: application of film in situ zymography.

Y. Tamura, H. Tanaka, Hidekazu Tanaka, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Correlation of antiangiogenic and antitumor efficacy of N-biphenyl sulfonyl-phenylalanine hydroxiamic acid (BPHA), an orally-active, selective matrix metalloproteinase inhibitor.

H. Tsuzuki, K. Sugita, H. Yoshida, 1999, Cancer research.

Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities.

S. Ōmura, R. Masuma, Y. Iwai, 1996, The Journal of antibiotics.

A deacylation enzyme for aculeacin A, a neutral lipopeptide antibiotic, from Actinoplanes utahensis: purification and characterization.

H. Tanaka, Y. Takada, H. Takeshima, 1989, Journal of Biochemistry (Tokyo).

[Discovery and development of a novel immunosuppressant, tacrolimus hydrate].

K. Nakahara, H. Tanaka, N. Inamura, 1997, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Chemical modification of anthracycline antibiotics IV. Synthesis of new anthracyclines with trisaccharide.

T. Oki, H. Tanaka, T. Ishikura, 1982, The Journal of antibiotics.

Preparation of 4- and 6-O-methyl-aclacinomycin derivatives and their antitumor activities.

T. Oki, H. Tanaka, T. Yoshioka, 1981, The Journal of antibiotics.

Chemical modification of anthracycline antibiotics. III. 4"'-Amino, 4"'-alkylamino acid 4"'-amide derivatives of aclacinomycin A.

T. Oki, H. Tanaka, T. Yoshioka, 1981, The Journal of antibiotics.

Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis

H. Ikeda, S. Ōmura, H. Tanaka, 1993, Journal of bacteriology.

F-244 specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A synthase.

S. Ōmura, H. Tomoda, H. Tanaka, 1987, Biochimica et biophysica acta.

Specific binding of beta-lactone 1233A to 3-hydroxy-3-methylglutaryl-coenzyme A synthase.

S. Ōmura, H. Tomoda, H. Tanaka, 1993, The Journal of antibiotics.

WF-2421, a new aldose reductase inhibitor produced from a fungus, Humicola grisea.

H. Hirota, H. Tanaka, M. Kohsaka, 1991, The Journal of antibiotics.

Synthesis and inhibitory activities of isochromophilone analogues against gp120-CD4 binding.

S. Ōmura, H. Tanaka, K. Furuhata, 1996, The Journal of antibiotics.

Studies on new vasodilators, WS-1228 A and B. II. Structure and synthesis.

H. Imanaka, H. Tanaka, Y. Itoh, 1982, Journal of antibiotics (Tokyo. 1968).

The site of inhibition of cell wall synthesis by 3-amino-3-deoxy-D-glucose in Staphylococcus aureus.

S. Ōmura, S. Shimizu, R. Oiwa, 1979, Journal of biochemistry.

[Antiangiogenic and antitumor effect of BPHA, an orally-active matrix metalloproteinase inhibitor, in in vivo murine and human tumor model].

H. Tsuzuki, K. Sugita, H. Yoshida, 1999, Gan to kagaku ryoho. Cancer & chemotherapy.

Construction of a single component producer from the wild type avermectin producer Streptomyces avermitilis.

H. Ikeda, S. Ōmura, H. Tanaka, 1995, The Journal of antibiotics.

Production of 6,8a-seco-6,8a-deoxy derivatives of avermectins by a mutant strain of Streptomyces avermitilis.

H. Ikeda, S. Ōmura, H. Tanaka, 1995, The Journal of antibiotics.

Direct production of 5-oxo derivatives of avermectins by a recombinant strain of Streptomyces avermitilis.

H. Ikeda, S. Ōmura, H. Tanaka, 1995, The Journal of antibiotics.

Ahpatinins, new acid protease inhibitors containing 4-amino-3-hydroxy-5-phenylpentanoic acid.

H. B. Woodruff, S. Ōmura, Y. Takahashi, 1986, The Journal of antibiotics.

Production of the new antibiotic tetrahydrokalafungin by transformants of the kalafungin producer Streptomyces tanashiensis.

H. Ikeda, S. Ōmura, D. Hopwood, 1995, Journal of antibiotics (Tokyo. 1968).

Isolation of restriction-reduced mutants from Streptomyces.

H. Ikeda, S. Ōmura, H. Tanaka, 1990, Agricultural and biological chemistry.

Total synthesis of WS9326A, a potent tachykinin antagonist from Streptomyces violaceoniger.

H. Tanaka, S. Okada, N. Shigematsu, 1997, Chemical & pharmaceutical bulletin.