Srivatsan Raghavan

发表

Simple approach to micropattern cells on common culture substrates by tuning substrate wettability.

Christopher S. Chen, C. Nelson, John L. Tan, 2004, Tissue engineering.

Cell polarity triggered by cell-cell adhesion via E-cadherin

Srivatsan Raghavan, Ravi A. Desai, Lin Gao, 2009, Journal of Cell Science.

Manipulation of 3D Cluster Size and Geometry by Release from 2D Micropatterns

Christopher S. Chen, Michael T. Yang, R. Chaturvedi, 2012, Cellular and molecular bioengineering.

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

James M. McFarland, T. Golub, G. Getz, 2019, Nature.

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition

Steven M. Corsello, Steve Carr, K. Ng, 2022, Nature Communications.

Metastatic Pancreatic Neuroendocrine Tumor with Ectopic Adrenocorticotropic Hormone Production

M. Vaduganathan, A. Fenves, J. C. Pallais, 2015, Proceedings.

Correction: KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

W. Hahn, A. Redig, N. Ilić, 2017, eLife.

FGFR2 Extracellular Domain In-Frame Deletions are Therapeutically Targetable Genomic Alterations that Function as Oncogenic Drivers in Cholangiocarcinoma.

Rachel B. Keller, W. Hahn, M. Meyerson, 2021, Cancer discovery.

Secondary IDH1 resistance mutations and oncogenic IDH2 mutations cause acquired resistance to ivosidenib in cholangiocarcinoma

P. Wen, N. Bardeesy, B. Wolpin, 2022, npj Precision Oncology.

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

James M. McFarland, Hannah L Williams, M. Tolstorukov, 2021, Cell.

The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer

James M. McFarland, Hannah L Williams, W. Hahn, 2020 .

Transcriptional subtype-specific microenvironmental crosstalk and tumor cell plasticity in metastatic pancreatic cancer

James M. McFarland, Hannah L Williams, W. Hahn, 2020, bioRxiv.

An inhibitory role for FAK in regulating proliferation: a link between limited adhesion and RhoA-ROCK signaling

Sami Alom Ruiz, Christopher S. Chen, D. Pirone, 2006, The Journal of cell biology.

Discovery of a selective inhibitor of Doublecortin Like Kinase 1

Charles Y. Lin, W. Hahn, A. Look, 2020, Nature Chemical Biology.

TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion-positive intrahepatic cholangiocarcinoma.

W. Hahn, G. Getz, A. Iafrate, 2019, Cancer discovery.

Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers.

Joshua M. Dempster, John A. Bachman, W. Hahn, 2019, Cell reports.

KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

John G Doench, W. Hahn, A. Redig, 2017, eLife.

Compressed phenotypic screens for complex multicellular models and high-content assays

Bryan D. Bryson, W. Hahn, B. Cleary, 2023, bioRxiv.

Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.

Christopher S. Chen, Jordan S. Miller, Xiang Yu, 2011, Experimental cell research.

Altered RNA Splicing by Mutant p53 Activates Oncogenic RAS Signaling in Pancreatic Cancer.

Sharon A. Lawrence, B. Taylor, S. Lowe, 2020, Cancer cell.

Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine.

Nicholas D. Camarda, Jeffrey W. Miller, W. Hahn, 2018, Cancer discovery.

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

James M. McFarland, T. Golub, G. Getz, 2018, bioRxiv.

iRGD-guided Tumor-penetrating Nanocomplexes for Therapeutic siRNA Delivery to Pancreatic Cancer

W. Hahn, T. Jacks, S. Bhatia, 2018, Molecular Cancer Therapeutics.

Phase Ib and Expansion Study of Gemcitabine, Nab-Paclitaxel, and Ficlatuzumab in Patients With Metastatic Pancreatic Cancer

W. Goessling, J. Meyerhardt, A. Rustgi, 2023, The oncologist.

Decoupling diffusional from dimensional control of signaling in 3D culture reveals a role for myosin in tubulogenesis

Ravi A. Desai, Christopher S. Chen, C. Nelson, 2010, Journal of Cell Science.

Geometrically controlled endothelial tubulogenesis in micropatterned gels.

Srivatsan Raghavan, Celeste M Nelson, Christopher S. Chen, 2010, Tissue engineering. Part A.

Degradation of Micropatterned Surfaces by Cell-Dependent and -Independent Processes †

Christopher S. Chen, C. Nelson, Srivatsan Raghavan, 2003 .

Opportunities for Utilization of DNA Repair Inhibitors in Homologous Recombination Repair-Deficient and Proficient Pancreatic Adenocarcinoma

G. Shapiro, A. D’Andrea, B. Wolpin, 2021, Clinical Cancer Research.

Abstract PR-006: Spatially resolved, single cell assessment of pancreatic ductal adenocarcinoma expression subtypes reveals mixed and hybrid basal-classical marker expression with prognostic significance and discrete spatial localization

W. Hahn, A. Koong, A. Hezel, 2020 .

Micropatterned dynamically adhesive substrates for cell migration.

Srivatsan Raghavan, Milan Mrksich, Ravi A. Desai, 2010, Langmuir : the ACS journal of surfaces and colloids.

Manipulation of 3D Cluster Size and Geometry by Release from 2D Micropatterns

Christopher S. Chen, R. Chaturvedi, Wendy F. Liu, 2012, Cellular and molecular bioengineering.

USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities

O. Sansom, B. Wolpin, A. Aguirre, 2023, Cell reports. Medicine.

Spatially-resolved single-cell assessment of pancreatic cancer expression subtypes reveals co-expressor phenotypes and extensive intra-tumoral heterogeneity.

A. Shalek, A. Koong, A. Hezel, 2022, Cancer research.

Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes.

Piyush K Jain, Justin H Lo, Santosh Rananaware, 2019, Nanoscale.

How we treat advanced biliary tract cancers in the second-line setting.

B. Wolpin, Srivatsan Raghavan, J. Cleary, 2023, Clinical advances in hematology & oncology : H&O.