Jacky Guy

发表

A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

A. Bird, B. Hendrich, M. Holmes, 2001, Nature Genetics.

Reversal of Neurological Defects in a Mouse Model of Rett Syndrome

A. Bird, S. Cobb, J. Selfridge, 2007, Science.

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

Robert S. Illingworth, A. Bird, D. Turner, 2010, Nature.

Explorer Gene Expression Analysis Exposes Mitochondrial Abnormalities in a Mouse Model of Rett Syndrome

A. Bird, N. MacLeod, S. Kriaucionis, 2017 .

Gene Expression Analysis Exposes Mitochondrial Abnormalities in a Mouse Model of Rett Syndrome

A. Bird, N. MacLeod, S. Kriaucionis, 2006, Molecular and Cellular Biology.

Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction

B. Ng, R. Klose, Andrew Dimond, 2020, Nature Communications.

Toxicity of overexpressed MeCP2 is independent of HDAC3 activity

A. Bird, M. Lazar, J. Selfridge, 2018, Genes & development.

Comparative analysis of potential broad-spectrum neuronal Cre drivers

A. Bird, J. Selfridge, Jacky Guy, 2022, Wellcome open research.

Affinity for DNA Contributes to NLS Independent Nuclear Localization of MeCP2

A. Bird, J. Selfridge, Cara Merusi, 2018, Cell reports.

Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes

A. Bird, S. Cobb, C. Loughrey, 2016, Human molecular genetics.

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome.

A. Bird, S. Cobb, G. Riedel, 2012, Brain : a journal of neurology.

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome

K. Vogt, Y. Barde, Jacky Guy, 2012, Proceedings of the National Academy of Sciences.

Gene Expression Analysis Exposes Mitochondrial Abnormalities in a Mouse Model of Rett Syndrome

A. Bird, N. MacLeod, S. Kriaucionis, 2006, Molecular and Cellular Biology.

1 Radically truncated MeCP 2 rescues Rett syndrome-like neurological defects 1

A. Bird, S. Cobb, J. Selfridge, 2017 .

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor

A. Bird, M. Greenberg, J. Rappsilber, 2013, Nature Neuroscience.

The role of MeCP2 in the brain.

Jim Selfridge, Adrian Bird, A. Bird, 2009, Annual review of cell and developmental biology.

Disease Modeling Using Embryonic Stem Cells: MeCP2 Regulates Nuclear Size and RNA Synthesis in Neurons

A. Bird, R. Poot, Y. Barde, 2012, Stem cells.

Cell type-specific DNA methylation at intragenic CpG islands in the immune system.

Robert S. Illingworth, A. Bird, R. Andrews, 2011, Genome research.

Systematic identification of factors bound to isolated metaphase ESC chromosomes reveals a role for chromatin repressors in compaction

B. Ng, Andrew Dimond, T. Bharat, 2019, bioRxiv.

Preclinical research in Rett syndrome: setting the foundation for translational success

Rodney C. Samaco, S. Nelson, H. Zoghbi, 2012, Disease Models & Mechanisms.

A mutation-led search for novel functional domains in MeCP2

A. Bird, J. Selfridge, Martha V. Koerner, 2018, bioRxiv.

The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome

A. Bird, J. Selfridge, Cara Merusi, 2015, Human molecular genetics.

Enhanced CpG Mutability and Tumorigenesis in MBD4-Deficient Mice

A. Bird, P. Keightley, O. Sansom, 2002, Science.

Radically truncated MeCP2 rescues Rett syndrome-like neurological defects

A. Bird, S. Cobb, J. Selfridge, 2017, Nature.

Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows.

A. Bird, J. Selfridge, Cara Merusi, 2012, Human molecular genetics.

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome.

A. Bird, H. Ropers, Tim C. Roloff, 2005, Human molecular genetics.

Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome

M. D'Esposito, L. Ricceri, G. Valacchi, 2014, Neurobiology of Disease.

DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution

L. Peichl, A. Bird, H. Leonhardt, 2014, Epigenetics & Chromatin.

Reversibility of functional deficits in experimental models of Rett syndrome.

A. Bird, S. Cobb, Jacky Guy, 2010, Biochemical Society transactions.

Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome

M. D'Esposito, L. Zolla, G. Valacchi, 2016, Neuroscience Research.

Brain protein changes in Mecp2 mouse mutant models: Effects on disease progression of Mecp2 brain specific gene reactivation.

L. Zolla, T. Durand, C. De Felice, 2020, Journal of proteomics.

Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

P. Klenerman, A. Mentzer, J. Marsh, 2022, medRxiv.

CpG islands influence chromatin structure via the CpG-binding protein Cfp1

Robert S. Illingworth, A. Bird, D. Turner, 2010, Nature.

Cell type-specific DNA methylation at intragenic CpG islands in the immune system.

Robert S. Illingworth, Shaun Webb, Jacky Guy, 2011, Genome research.

The role of MeCP2 in the brain.

A. Bird, J. Selfridge, Jacky Guy, 2011, Annual review of cell and developmental biology.

Edinburgh Research Explorer Cpg Islands Influence Chromatin Structure via the Cpg-binding Protein Cfp1 Cpg Islands Influence Chromatin Structure via the Cpg-binding Protein Cfp1 Europe Pmc Funders Group

Robert S. Illingworth, J. Selfridge, Shaun Webb, 2022 .