P. Hayes

发表

Standardization of cytokine flow cytometry assays

M. Altfeld, R. Koup, V. Maino, 2005, BMC Immunology.

Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1

G. Dickson, K. Fisher, A. Lieber, 2009, Proceedings of the National Academy of Sciences.

Parameters of Human Immunodeficiency Virus Infection of Human Cervical Tissue and Inhibition by Vaginal Virucides

P. Watts, R. Shattock, G. Griffin, 2000, Journal of Virology.

Prospective Study of the Effects of Antiretroviral Therapy on Kaposi Sarcoma‐Associated Herpesvirus Infection in Patients With and Without Kaposi Sarcoma

B. Gazzard, C. Boshoff, V. Calvez, 2002, Journal of acquired immune deficiency syndromes.

Engagement of adhesion molecules (CD18, CD11a, CD45, CD44, and CD58) enhances human immunodeficiency virus type 1 replication in monocytic cells through a tumor necrosis factor-modulated pathway.

R. Shattock, G. Griffin, P. Hayes, 1996, The Journal of infectious diseases.

Non-Immunogenicity of Overlapping Gag Peptides Pulsed on Autologous Cells after Vaccination of HIV Infected Individuals

B. Walker, P. Goulder, M. Boffito, 2013, PloS one.

A Randomised, Placebo-Controlled, First-In-Human Study of a Novel Clade C Therapeutic Peptide Vaccine Administered Ex Vivo to Autologous White Blood Cells in HIV Infected Individuals

B. Walker, P. Goulder, M. Boffito, 2013, PloS one.

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers.

S. Kochhar, J. Excler, P. Fast, 2009, AIDS research and human retroviruses.

Human immunodeficiency virus infection impairs hemopoiesis in long-term bone marrow cultures: nonreversal by nucleoside analogues.

R. Shattock, G. Griffin, P. Hayes, 1997, The Journal of infectious diseases.

Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa.

P. Kaleebu, A. McMichael, S. Wakasiaka, 2008, Vaccine.

Performance of an IAVI-African Network of Clinical Research Laboratories in Standardized ELISpot and Peripheral Blood Mononuclear Cell Processing in Support of HIV Vaccine Clinical Trials

N. Hills, O. Anzala, G. Omosa-Manyonyi, 2018, bioRxiv.

Molecular correlates in AIDS patients following antiretroviral therapy: diversified T‐cell receptor repertoires and in vivo control of cytomegalovirus replication

B. Gazzard, P. Hayes, F. Gotch, 2001, HIV medicine.

Left main coronary artery disease in a 40-year-old man receiving HIV protease inhibitors.

D. Kuchar, P. Hayes, D. Muller, 2000, Australian and New Zealand journal of medicine.

Elevated mucosal addressin cell adhesion molecule-1 expression in acquired immunodeficiency syndrome is maintained during antiretroviral therapy by intestinal pathogens and coincides with increased duodenal CD4 T cell densities.

B. Gazzard, P. Hayes, F. Gotch, 2002, The Journal of infectious diseases.

Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers.

S. McCormack, A. McMichael, J. Weber, 2008, Vaccine.

Eradication of Cryptosporidia and Microsporidia Following Successful Antiretroviral Therapy

B. Gazzard, A. Müller, P. Hayes, 2000, Journal of acquired immune deficiency syndromes.

Eradication of cryptosporidia and microsporidia following successful antiretroviral therapy.

B. Gazzard, A. Müller, P. Hayes, 2000 .

Identification of Kaposi's Sarcoma-Associated Herpesvirus (KSHV)-Specific Cytotoxic T-Lymphocyte Epitopes and Evaluation of Reconstitution of KSHV-Specific Responses in Human Immunodeficiency Virus Type 1-Infected Patients Receiving Highly Active Antiretroviral Therapy

B. Gazzard, C. Boshoff, V. Calvez, 2002, Journal of Virology.

Comprehensive epitope mapping using polyclonally expanded human CD8 T cells and a two-step ELISpot assay for testing large peptide libraries.

A. Fiore-Gartland, E. Hunter, P. Hayes, 2021, Journal of immunological methods.

Equivalence of ELISpot Assays Demonstrated between Major HIV Network Laboratories

S. Self, P. Kaleebu, R. Koup, 2010, PloS one.

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of Electroporated HIV DNA with or without Interleukin 12 in Prime-Boost Combinations with an Ad35 HIV Vaccine in Healthy HIV-Seronegative African Adults

E. Karita, O. Anzala, J. Eldridge, 2015, PloS one.

Specificity of CD8+ T-Cell Responses Following Vaccination with Conserved Regions of HIV-1 in Nairobi, Kenya

Y. S. Mohamed, C. Brander, W. Jaoko, 2020, Vaccines.

Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1.

Lucy Dorrell, Nicole Frahm, Josephine Cox, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Intra- and Inter-clade Cross-reactivity by HIV-1 Gag Specific T-Cells Reveals Exclusive and Commonly Targeted Regions: Implications for Current Vaccine Trials

C. Gray, C. Williamson, L. Bekker, 2011, PloS one.

Assessment of the Safety and Immunogenicity of 2 Novel Vaccine Platforms for HIV-1 Prevention: A Randomized Trial.

N. Frahm, E. Karita, M. McElrath, 2016, Annals of internal medicine.

A DNA-Based Candidate HIV Vaccine Delivered via In Vivo Electroporation Induces CD4 Responses toward the α4β7-Binding V2 Loop of HIV gp120 in Healthy Volunteers

S. Vasan, P. Hayes, J. Cox, 2012, Clinical and Vaccine Immunology.

Broad HIV-1 inhibition in vitro by vaccine-elicited CD8+ T cells in African adults

W. Jaoko, O. Anzala, T. Hanke, 2016, Molecular therapy. Methods & clinical development.

Efficient Killing of Infected Cells, Production of Soluble Antiviral Factors T Cells in African Adults

W. Jaoko, O. Anzala, T. Hanke, 2022 .

Assessment of a diverse panel of transmitted/founder HIV-1 infectious molecular clones in a luciferase based CD8 T-cell mediated viral inhibition assay

E. Nduati, E. Hunter, L. Yue, 2022, Frontiers in Immunology.

Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial

S. McCormack, R. Shattock, P. Hayes, 2017, Scientific Reports.

Adenovirus-based HIV-1 vaccine candidates tested in efficacy trials elicit CD8+ T cells with limited breadth of HIV-1 inhibition

S. Nitayaphan, M. de Souza, P. Hayes, 2016, AIDS.

Development of a luciferase based viral inhibition assay to evaluate vaccine induced CD8 T-cell responses.

J. Kappes, O. Anzala, T. Hanke, 2014, Journal of immunological methods.

Viral inhibition assay: a CD8 T cell neutralization assay for use in clinical trials of HIV-1 vaccine candidates.

B. Walker, E. Karita, O. Anzala, 2010, The Journal of infectious diseases.

Continentsin Laboratories from Three Cell and Enzyme-Linked Immunospot Trials by Peripheral Blood Mononuclear Immunodeficiency Virus Vaccine Clinical T-Cell Immunity in Human Concordant Proficiency in Measurement of

P. Kaleebu, J. Birungi, M. Thakar, 2014 .

Concordant Proficiency in Measurement of T-Cell Immunity in Human Immunodeficiency Virus Vaccine Clinical Trials by Peripheral Blood Mononuclear Cell and Enzyme-Linked Immunospot Assays in Laboratories from Three Continents

P. Kaleebu, O. Anzala, J. Birungi, 2008, Clinical and Vaccine Immunology.

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013–2016 West Africa Ebola outbreak in Guinea

M. Kieny, R. Grais, Y. Boum, 2020, Vaccine.

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens

S. Kent, C. Pinder, P. McKay, 2017, Front. Immunol..

Safety and Immunogenicity of DNA Prime and Modified Vaccinia Ankara Virus-HIV Subtype C Vaccine Boost in Healthy Adults

B. Gazzard, G. Alter, M. Boffito, 2013, Clinical and Vaccine Immunology.

A Phase I Double Blind, Placebo-Controlled, Randomized Study of a Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected Adults

J. Excler, P. Fast, P. Hayes, 2012, PloS one.

Safety and Immunogenicity Study of Multiclade HIV-1 Adenoviral Vector Vaccine Alone or as Boost following a Multiclade HIV-1 DNA Vaccine in Africa

R. Koup, E. Karita, G. Nabel, 2010, PloS one.

A Novel Sample Selection Approach to Aid the Identification of Factors That Correlate With the Control of HIV-1 Infection

E. Nduati, E. Hunter, A. Freni-Sterrantino, 2021, Frontiers in Immunology.

©MultiHIV DNA Vaccine Delivered by Transcutaneous and Intramuscular Injection With or Without Electroporation in HIV-1 Positive Subjects

S. McCormack, R. Shattock, P. Hayes, 2020 .

The Safety and Immunogenicity of GTU®MultiHIV DNA Vaccine Delivered by Transcutaneous and Intramuscular Injection With or Without Electroporation in HIV-1 Positive Subjects on Suppressive ART

S. McCormack, R. Shattock, P. Hayes, 2019, Front. Immunol..

Cohort-Specific Peptide Reagents Broaden Depth and Breadth Estimates of the CD8 T Cell Response to HIV-1 Gag Potential T Cell Epitopes

A. Fiore-Gartland, E. Hunter, P. Hayes, 2023, Vaccines.

Induction of Multifunctional Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T Cells Capable of Proliferation in Healthy Subjects by Using a Prime-Boost Regimen of DNA- and Modified Vaccinia Virus Ankara-Vectored Vaccines Expressing HIV-1 Gag Coupled to CD8+ T-Cell Epitopes

Lucy Dorrell, Andrew J. McMichael, Jill Gilmour, 2006, Journal of Virology.

Performance of serum-supplemented and serum-free media in IFNγ Elispot Assays for human T cells

S. H. van der Burg, G. Ferrari, E. Kaempgen, 2009, Cancer Immunology, Immunotherapy.

Vaccination with a modified vaccinia virus Ankara (MVA)-vectored HIV-1 immunogen induces modest vector-specific T cell responses in human subjects.

A. McMichael, T. Hanke, P. Hayes, 2010, Vaccine.

Control of HIV-1 replication in vitro by vaccine-induced human CD8+ T cells through conserved subdominant Pol epitopes

T. Hanke, P. Hayes, J. Gilmour, 2016, Vaccine.

Broad HIV Epitope Specificity and Viral Inhibition Induced by Multigenic HIV-1 Adenovirus Subtype 35 Vector Vaccine in Healthy Uninfected Adults

J. Excler, J. Czyzewska-Khan, P. Fast, 2014, PloS one.

A Comparative Phase I Study of Combination, Homologous Subtype-C DNA, MVA, and Env gp140 Protein/Adjuvant HIV Vaccines in Two Immunization Regimes

S. McCormack, D. Montefiori, J. Weber, 2017, Front. Immunol..

A Phase I Double Blind, Placebo-Controlled, Randomized Study of the Safety and Immunogenicity of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein and Adenovirus 35 Gag-RT-Int-Nef Vaccine in Healthy HIV-Uninfected African Adults

G. Omosa-Manyonyi, E. Chomba, J. Mpendo, 2015, PloS one.

Evidence of thymic reconstitution after highly active antiretroviral therapy in HIV‐1 infection

B. Gazzard, P. Hayes, R. Aspinall, 2004, HIV medicine.

Breadth of CD8 T-cell mediated inhibition of replication of diverse HIV-1 transmitted-founder isolates correlates with the breadth of recognition within a comprehensive HIV-1 Gag, Nef, Env and Pol potential T-cell epitope (PTE) peptide set

E. Hunter, P. Hayes, J. Gilmour, 2021, PloS one.

First-in-Human Evaluation of the Safety and Immunogenicity of an Intranasally Administered Replication-Competent Sendai Virus–Vectored HIV Type 1 Gag Vaccine: Induction of Potent T-Cell or Antibody Responses in Prime-Boost Regimens

B. Gazzard, E. Karita, O. Anzala, 2016, The Journal of infectious diseases.

Performance of International AIDS Vaccine Initiative African clinical research laboratories in standardised ELISpot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials

N. Hills, O. Anzala, G. Omosa-Manyonyi, 2021, African journal of laboratory medicine.

Measuring human T cell responses in blood and gut samples using qualified methods suitable for evaluation of HIV vaccine candidates in clinical trials.

Frances Gotch, Peter Kelleher, Ambreen Ashraf, 2011, Journal of immunological methods.

HIV-1 infection and the lack of viral control are associated with greater expression of interleukin-21 receptor on CD8+ T cells

P. Hayes, J. Gilmour, S. L. Black, 2021, AIDS.

Combined skin and muscle vaccination differentially impact the quality of effector T cell functions: the CUTHIVAC-001 randomized trial

S. McCormack, R. Shattock, P. Hayes, 2017, Scientific Reports.

Evaluation of antiviral T cell responses and TSCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India

S. Swaminathan, Rajat Goyal, P. Hayes, 2020, PloS one.

A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus.

Philip R. Johnson, P. Kaleebu, L. Bekker, 2010, AIDS research and human retroviruses.

Increase in plasma viral load after oral cholera immunization of HIV‐infected subjects

R. Shattock, A. P. de Leon, G. Griffin, 1998, AIDS.

Clade A HIV-1 Gag-Specific T Cell Responses Are Frequent but Do Not Correlate with Viral Loads in a Cohort of Treatment-Naïve HIV-Infected Individuals Living in Guinea-Bissau

A. Fomsgaard, C. M. Rodrigues, P. Hayes, 2012, Clinical and Vaccine Immunology.

A Phase 1 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 subtype C-modified vaccinia Ankara virus vaccine candidate in Indian volunteers.

S. Kochhar, J. Excler, P. Fast, 2009, AIDS research and human retroviruses.

A phase 2 study to evaluate the safety and immunogenicity of a recombinant HIV type 1 vaccine based on adeno-associated virus.

Philip R. Johnson, P. Kaleebu, L. Bekker, 2010, AIDS research and human retroviruses.