Ann Chen

B. Tang, Yuh-Feng Lin, T. Chao, 2008, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Uremia Induces Dental Pulp Ossification but Reciprocally Inhibits Adjacent Alveolar Bone Osteogenesis

O. Lee, Y. Chau, Z. Chang, 2015, Calcified Tissue International.

Decoy receptor 3 inhibits renal mononuclear leukocyte infiltration and apoptosis and prevents progression of IgA nephropathy in mice.

Shih-Hua Lin, S. Yang, H. Sytwu, 2011, American journal of physiology. Renal physiology.

IgA immune complex blunts the contraction of cultured mesangial cells through the inhibition of protein kinase C and intracellular calcium.

Wei-Hwa Lee, T. Chin, S. Chueh, 2004, The Chinese journal of physiology.

Matriptase and Survivin Expression Associated with Tumor Progression and Malignant Potential in Breast Cancer of Chinese Women: Tissue Microarray Analysis of Immunostaining Scores with Clinicopathological Parameters

C. Chu, Jong-Shiaw Jin, Ann Chen, 2008, Disease markers.

Citral Is Renoprotective for Focal Segmental Glomerulosclerosis by Inhibiting Oxidative Stress and Apoptosis and Activating Nrf2 Pathway in Mice

K. Hua, Ann Chen, Jia-Ming Chang, 2013, PloS one.

Association of EMMPRIN and fascin expression in renal cell carcinoma: correlation with clinicopathological parameters

S. Nieh, Cheng-Ping Yu, Jong-Shiaw Jin, 2007, World Journal of Urology.

Association between Osteopontin and EGFR Expression with Clinicopathological Parameters in Hepatocellular Carcinoma.

D. Chan, S. Nieh, T. Chao, 2012, The Chinese journal of physiology.

Experimental IgA nephropathy: factors influencing IgA-immune complex deposition in the glomerulus

Wei-Hwa Lee, Ann Chen, Chian-Hwa Wei, 2004, Springer Seminars in Immunopathology.

Xenon blunts NF-κB/NLRP3 inflammasome activation and improves acute onset of accelerated and severe lupus nephritis in mice.

Hailin Zhao, D. Ma, K. Hua, 2020, Kidney international.

IgA nephropathy: clearance kinetics of IgA-containing immune complexes

S. Yang, Ann Chen, S. Ka, 2018, Seminars in Immunopathology.

Compound K inhibits priming and mitochondria-associated activating signals of NLRP3 inflammasome in renal tubulointerstitial lesions.

K. Hua, C. Chu, Y. Hsu, 2019, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Cf‐02, a novel benzamide‐linked small molecule, blunts NF‐κB activation and NLRP3 inflammasome assembly and improves acute onset of accelerated and severe lupus nephritis in mice

D. Mukhopadhyay, K. Hua, Y. Hsu, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Accelerated, severe lupus nephritis benefits from treatment with honokiol by immunoregulation and differentially regulating NF‐κB/NLRP3 inflammasome and sirtuin 1/autophagy axis

K. Hua, Feng-Cheng Liu, Ann Chen, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antroquinonol differentially modulates T cell activity and reduces interleukin-18 production, but enhances Nrf2 activation, in murine accelerated severe lupus nephritis.

Mao-Tien Kuo, Peini Chen, J. Lai, 2012, Arthritis and rheumatism.

Citral alleviates an accelerated and severe lupus nephritis model by inhibiting the activation signal of NLRP3 inflammasome and enhancing Nrf2 activation

K. Hua, H. Sytwu, Feng-Cheng Liu, 2015, Arthritis Research & Therapy.

Characterization of neutralizing monoclonal antibodies recognizing a 15-residues epitope on the spike protein HR2 region of severe acute respiratory syndrome coronavirus (SARS-CoV)

J. Jan, P. Chong, S. Lai, 2005, Journal of Biomedical Sciences.

Differential synchrotron X-ray imaging markers based on the renal microvasculature for tubulointerstitial lesions and glomerulopathy

Ting-Kuo Lee, M. Hsiao, Y. Hwu, 2017, Scientific Reports.

EFFECTS OF A MEMBRANE-PERMEABLE RADICAL SCAVENGER, TEMPOL, ON INTRAPERITONEAL SEPSIS-INDUCED ORGAN INJURY IN RATS

C. Tzao, W. Liaw, Ann Chen, 2005, Shock.

Rab23 plays a role in the pathophysiology of mesangial cells – A proteomic analysis

B. Tang, Junn-Liang Chang, Y. Hsu, 2011, Proteomics.

Adriamycin impairs the contraction of mesangial cells through the inhibition of protein kinase C and intracellular calcium.

Wei-Hwa Lee, T. Chin, S. Chueh, 2004, American journal of physiology. Renal physiology.

Differential immunomodulatory effects by Tripterygium wilfordii Hook f-derived refined extract PG27 and its purified component PG490 (triptolide) in human peripheral blood T cells: potential therapeutics for arthritis and possible mechanisms explaining in part Chinese herbal theory “Junn-Chenn-Zuou-

Ling-Jun Ho, J. Lai, Ann Chen, 2013, Journal of Translational Medicine.

Resveratrol increases anti-aging Klotho gene expression via the activating transcription factor 3/c-Jun complex-mediated signaling pathway.

Shih-Ming Huang, Shih-Hua Lin, Y. Hsu, 2014, The international journal of biochemistry & cell biology.

Glucosamine inhibits IL-1β expression by preserving mitochondrial integrity and disrupting assembly of the NLRP3 inflammasome

Y. K. Rao, K. Hua, Ann Chen, 2019, Scientific Reports.

Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy

K. Hua, Ming-Cheng Chen, Ann Chen, 2015, Journal of cellular physiology.

3D Digital Pathology for a Chemical-Functional Analysis of Glomeruli in Health and Pathology.

Y. Hwu, C. Petibois, Hsiang-Hsin Chen, 2018, Analytical chemistry.

Proteomic analysis and identification of aqueous humor proteins with a pathophysiological role in diabetic retinopathy.

Y. Chou, Ann Chen, Chih-Yuan Wang, 2012, Journal of proteomics.

Pulmonary function changes and immunomodulation of Th 2 cytokine expression induced by aminophylline after sensitization and allergen challenge in brown Norway rats.

Ann Chen, Ching-Chi Lin, Shwu-Fang Liaw, 2002, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Propofol ameliorates liver dysfunction and inhibits aortic superoxide level in conscious rats with endotoxic shock.

S. Ho, Jhi-Joung Wang, Ann Chen, 2003, European journal of pharmacology.

(S)-armepavine from Chinese medicine improves experimental autoimmune crescentic glomerulonephritis.

Y. Hsu, Yun-Lian Lin, Ann Chen, 2010, Rheumatology.

Osteopontin as an injury marker expressing in epithelial hyperplasia lesions helpful in prognosis of focal segmental glomerulosclerosis.

Yuh-Feng Lin, Yi-Fen Lo, Ann Chen, 2007, Translational research : the journal of laboratory and clinical medicine.

Glomerular crescent-related biomarkers in a murine model of chronic graft versus host disease.

Yuh-Feng Lin, Herng‐Sheng Lee, Ann Chen, 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Decoy receptor 3 ameliorates an autoimmune crescentic glomerulonephritis model in mice.

S. Hsieh, D. Chang, H. Sytwu, 2007, Journal of the American Society of Nephrology : JASN.

Thrombomodulin domain 1 ameliorates diabetic nephropathy in mice via anti-NF-κB/NLRP3 inflammasome-mediated inflammation, enhancement of NRF2 antioxidant activity and inhibition of apoptosis

Y. Hung, Jeng-Shin Lee, K. Hua, 2014, Diabetologia.

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

K. Hua, Ann Chen, L. Chao, 2012, Inflammation Research.

Combined effects of propofol and dexamethasone on rats with endotoxemia

S. Ho, W. Liaw, Ann Chen, 2008, Critical care medicine.

LOW-DOSE DEXAMETHASONE AMELIORATES CIRCULATORY FAILURE AND RENAL DYSFUNCTION IN CONSCIOUS RATS WITH ENDOTOXEMIA

S. Ho, Chi-Yuan Li, Jhi-Joung Wang, 2004, Shock.

LCC18, a benzamide‐linked small molecule, ameliorates IgA nephropathy in mice

D. Mukhopadhyay, Yusuke Suzuki, K. Hua, 2020, The Journal of pathology.

Cyclooxygenase‐2 Regulates NLRP3 Inflammasome‐Derived IL‐1β Production

Shih-Hsiung Wu, K. Hua, Ann Chen, 2015, Journal of cellular physiology.

Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation

Shih-Hsiung Wu, K. Hua, Yu-Liang Yang, 2013, PloS one.

Bamboo Vinegar Decreases Inflammatory Mediator Expression and NLRP3 Inflammasome Activation by Inhibiting Reactive Oxygen Species Generation and Protein Kinase C-α/δ Activation

K. Hua, Ann Chen, S. Ka, 2013, PloS one.

Tris DBA ameliorates IgA nephropathy by blunting the activating signal of NLRP3 inflammasome through SIRT1‐ and SIRT3‐mediated autophagy induction

J. Arbiser, K. Hua, Yi-Shan Tsai, 2020, Journal of cellular and molecular medicine.

Persistent Transforming Growth Factor-Beta 1 Expression May Predict Peritoneal Fibrosis in CAPD Patients with Frequent Peritonitis Occurrence

Ann Chen, Tung-Po Huang, Wei-Perng Chen, 1998, American Journal of Nephrology.

Osthole improves an accelerated focal segmental glomerulosclerosis model in the early stage by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated COX-2 expression and apoptosis.

Shih-Hsiung Wu, K. Hua, Yi-Lin Chan, 2014, Free radical biology & medicine.

Expression of Serine Protease Matriptase in Renal Cell Carcinoma: Correlation of Tissue Microarray Immunohistochemical Expression Analysis Results with Clinicopathological Parameters

Jong-Shiaw Jin, Ann Chen, D. Hsieh, 2006, International journal of surgical pathology.

Biphasic effects of exogenous phospholipase D on vessel tone.

Wei-Hwa Lee, Jong-Shiaw Jin, Ann Chen, 2002, The Chinese journal of physiology.

Dual biological functions of an interleukin‐1 receptor antagonist–interleukin‐10 fusion protein and its suppressive effects on joint inflammation

S. Shyue, D. Chang, J. Lai, 2004, Immunology.

IL-36 Signaling Facilitates Activation of the NLRP3 Inflammasome and IL-23/IL-17 Axis in Renal Inflammation and Fibrosis.

K. Hua, C. Chu, Y. Hsu, 2017, Journal of the American Society of Nephrology : JASN.

Fibronectin in blood invokes the development of focal segmental glomerulosclerosis in mouse model.

Yuh-Feng Lin, Jong-Shiaw Jin, Ann Chen, 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice.

Mao-Tien Kuo, Peini Chen, T. Chao, 2011, Free radical biology & medicine.

Mitochondrial CMPK2 mediates immunomodulatory and antiviral activities through IFN-dependent and IFN-independent pathways

Ling-Jun Ho, J. Lai, Z. Chang, 2021, iScience.

Uremia Induces Dental Pulp Ossification but Reciprocally Inhibits Adjacent Alveolar Bone Osteogenesis

O. Lee, Y. Chau, Z. Chang, 2015, Calcified Tissue International.

Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis.

Yuh-Feng Lin, Ann Chen, H. Shui, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Updated survival, toxicity, and biomarkers of nivolumab with/without peptide vaccine in patients naive to, or progressed on, ipilimumab (IPI).

G. Gibney, E. Welsh, J. Weber, 2014 .

Retracted: Evidence for the early involvement of interleukin 17 in human and experimental renal allograft rejection

W. Lui, Ann Chen, H. Hsieh, 2002, The Journal of pathology.

Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway

K. Hua, S. Yang, Ann Chen, 2013, PloS one.

Effects of terbutaline on circulatory failure and organ dysfunction induced by peritonitis in rats

W. Liaw, M. Tsou, Ann Chen, 2010, Intensive Care Medicine.

Antroquinonol mitigates an accelerated and progressive IgA nephropathy model in mice by activating the Nrf2 pathway and inhibiting T cells and NLRP3 inflammasome.

Shih-Hsiung Wu, K. Hua, Shih-Hua Lin, 2013, Free radical biology & medicine.

Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation.

K. Hua, Hsian-Cheng Chen, S. Yang, 2011, Free radical biology & medicine.

IgA Nephropathy Benefits from Compound K Treatment by Inhibiting NF-κB/NLRP3 Inflammasome and Enhancing Autophagy and SIRT1

Yusuke Suzuki, L. Chu, D. Nikolic-Paterson, 2020, The Journal of Immunology.

IgA nephropathy: clearance kinetics of IgA-containing immune complexes

S. Yang, Ann Chen, S. Ka, 2018, Seminars in Immunopathology.

Co‐expression of c‐kit and stem cell factor in primary and metastatic nasopharyngeal carcinomas and nasopharyngeal epithelium

Wen-Cheng Lee, Herng‐Sheng Lee, Ann Chen, 2005, The Journal of pathology.

Ling-Jun Ho, J. Lai, Ann Chen, 2013, Journal of Translational Medicine.

Quercetin induced cell apoptosis and altered gene expression in AGS human gastric cancer cells

Jing-Gung Chung, Yuh-Feng Lin, Ann Chen, 2018, Environmental toxicology.

Prognostic and Predictive Value of an Immunoscore Signature in Glioblastoma Multiform

Ann Chen, Gang Deng, Qianxue Chen, 2020, Frontiers in Genetics.

Discordance between EGFR expression and clinicopathologic parameters of colorectal adenocarcinoma in Taiwan.

S. Nieh, S. Jao, Cheng-Ping Yu, 2012, The Chinese journal of physiology.

Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion

Ann Chen, L. Chao, S. Ka, 2012, Inflammation Research.

The MTNR1A mRNA is stabilized by the cytoplasmic hnRNPL in renal tubular cells

H. Shih, T. Chao, K. Lu, 2020, Journal of cellular physiology.

Casticin induced apoptotic cell death and altered associated gene expression in human colon cancer colo 205 cells

Jing-Gung Chung, Yuh-Feng Lin, Ann Chen, 2017, Environmental toxicology.

Urine Annexin A1 as an Index for Glomerular Injury in Patients

Y. Hung, T. Chao, Ann Chen, 2014, Disease markers.

STI571 sensitizes nasopharyngeal carcinoma cells to cisplatin: sustained activation of ERK with improved growth inhibition.

Wen-Cheng Lee, Ann Chen, L. Sheu, 2007, International journal of oncology.

Impact of taxol on dermal papilla cells--a proteomics and bioinformatics analysis.

M. Tseng, Ann Chen, Chih-Yuan Wang, 2011, Journal of proteomics.

Role of melatonin receptor 1A and pituitary homeobox‐1 coexpression in protecting tubular epithelial cells in membranous nephropathy

H. Shih, T. Chao, K. Lu, 2018, Journal of pineal research.

Oxidized cellulose (Surgicel) granuloma mimicking a primary ovarian tumor.

Cheng-Ping Yu, Ann Chen, Chih-kung Lin, 2002, International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists.

Therapeutic effects of hypertonic saline on peritonitis-induced septic shock with multiple organ dysfunction syndrome in rats*

W. Liaw, Ann Chen, Jeng-Yuan Wu, 2008, Critical care medicine.

Nephronectin expression in nephrotoxic acute tubular necrosis.

Ann Chen, H. Shui, S. Ka, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Mesangial cells of lupus-prone mice are sensitive to chemokine production

D. Chang, Wen-Mein Wu, Ann Chen, 2007, Arthritis research & therapy.

Decreased matriptase/HAI-1 ratio in advanced colorectal adenocarcinoma of Chinese patients.

Jong-Shiaw Jin, Ann Chen, Y. Chao, 2007, The Chinese journal of physiology.

Pathogenesis of IgA nephropathy: In vitro activation of human mesangial cells by IgA immune complex leads to cytokine secretion

Ann Chen, C. Y. Lin, L. Sheu, 1994, The Journal of pathology.

EMMPRIN and fascin overexpression associated with clinicopathologic parameters of pancreatobiliary adenocarcinoma in Chinese people

S. Nieh, Jong-Shiaw Jin, Ann Chen, 2007, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Fasciitis Ossificans of the Breast

Ann Chen, Ting-Fu Su, 2014, The Breast Journal.

Behavior of Cutaneous Adnexal Malignancies: a Single Institution Experience

V. Sondak, J. Messina, B. Yue, 2018, Pathology & Oncology Research.

Attenuation of Mouse Mesangial Cell Contractility by High Glucose and Mannitol: Involvement of Protein Kinase C and Focal Adhesion Kinase

Yuh-Feng Lin, Shih-Hua Lin, Jong-Shiaw Jin, 2004, Journal of Biomedical Science.

Mouse model of membranous nephropathy induced by cationic bovine serum albumin: antigen dose-response relations and strain differences.

Yuh-Feng Lin, Shih-Hua Lin, W. Chang, 2004, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Calcium-binding proteins annexin A2 and S100A6 are sensors of tubular injury and recovery in acute renal failure.

Wei-Hwa Lee, Yuh-Feng Lin, Ann Chen, 2005, Kidney international.

A low toxicity synthetic cinnamaldehyde derivative ameliorates renal inflammation in mice by inhibiting NLRP3 inflammasome and its related signaling pathways.

Shui-Tein Chen, Ann Chen, Jung-Chen Lin, 2016, Free radical biology & medicine.

Rapid and sensitive detection of multiple genes from the SARS‐Coronavirus using quantitative RT‐PCR with dual systems

K. Peck, Chang-Shen Lin, Yu-Ming Wang, 2005, Journal of medical virology.

Melatonin prevents endotoxin‐induced circulatory failure in rats

Ann Chen, M. Yen, G. Hsiao, 2001, Journal of pineal research.

Mechanistic Insight Into the Activation of the NLRP3 Inflammasome by Neisseria gonorrhoeae in Macrophages

O. Chernikov, Ann Chen, Chung-Hua Hsu, 2019, Front. Immunol..

4,4'-Methylenebis(2-chloroaniline) (MBOCA) May Be Highly Toxic and a Carcinogen Based on an Experimental Study with Mice

Chien-Feng Li, Yi-Chiang Hsu, S. Liou, 2014 .