J. A. Gaspar

发表

Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests

J. Rahnenführer, J. Hengstler, M. Leist, 2016, Archives of Toxicology.

High-efficient serum-free differentiation of endothelial cells from human iPS cells

J. Hescheler, K. Pfannkuche, A. Sachinidis, 2022, Stem Cell Research & Therapy.

Specific Gene Signatures and Pathways in Mesodermal Cells and Their Derivatives Derived from Embryonic Stem Cells

Herbert Schulz, Jürgen Hescheler, Michael Xavier Doss, 2012, Stem Cell Reviews and Reports.

Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca2+ release channel

A. Brunn, M. Deckert, J. Hescheler, 2016, Scientific Reports.

Functional Characterization and Gene Expression Profiling of α-Smooth Muscle Actin Expressing Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells

K. Meganathan, K. Pfannkuche, A. Sachinidis, 2011, Stem Cell Reviews and Reports.

Mesoderm-derived stem cells: the link between the transcriptome and their differentiation potential.

J. Bolleyn, T. Vanhaecke, V. Rogiers, 2012, Stem cells and development.

Effects of Cryopreservation on the Transcriptome of Human Embryonic Stem Cells After Thawing and Culturing

D. Spitkovsky, V. Wagh, K. Meganathan, 2011, Stem Cell Reviews and Reports.

Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies

D. Spitkovsky, K. Meganathan, K. Pfannkuche, 2013, Stem Cell Reviews and Reports.

Neuronal-Specific Deficiency of the Splicing Factor Tra2b Causes Apoptosis in Neurogenic Areas of the Developing Mouse Brain

B. Wirth, K. Meganathan, A. Sachinidis, 2014, PloS one.

Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives

J. Hescheler, M. Doss, A. Sachinidis, 2017, Scientific Reports.

Extensive Transcriptional Regulation of Chromatin Modifiers during Human Neurodevelopment

Tanja Waldmann, Marc P. Broeg, Marcel Leist, 2012, PloS one.

Unique Metabolic Features of Stem Cells, Cardiomyocytes, and Their Progenitors

J. Hengstler, C. Cadenas, J. Hescheler, 2014, Circulation research.

Gene expression signatures defining fundamental biological processes in pluripotent, early, and late differentiated embryonic stem cells.

Raivo Kolde, Jaak Vilo, Herbert Schulz, 2012, Stem cells and development.

Stem cells and differentiation – a synoptic review of patents granted since 2009

J. Hescheler, A. Sachinidis, J. A. Gaspar, 2015, Expert opinion on therapeutic patents.

Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells

Raivo Kolde, Tanja Waldmann, Jan G. Hengstler, 2014, Chemical research in toxicology.

Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells

H. Schlüter, V. Wagh, K. Meganathan, 2012, PloS one.

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment

James K. Ellis, J. Hengstler, H. Keun, 2015, Archives of Toxicology.

MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes

J. Hengstler, J. Hescheler, A. Sachinidis, 2016, Archives of Toxicology.

Specific Gene Signatures and Pathways in Mesodermal Cells and Their Derivatives Derived from Embryonic Stem Cells

H. Schulz, J. Hescheler, M. Doss, 2012, Stem Cell Reviews and Reports.

Corrigendum: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca2+ release channel

A. Brunn, M. Deckert, J. Hescheler, 2016, Scientific Reports.

Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: effects of CREB pathway inhibition.

G. Basso, B. Accordi, F. Pistollato, 2014, Toxicology and applied pharmacology.

STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation

V. Wagh, J. Hescheler, H. Abken, 2017, Molecular therapy. Methods & clinical development.

Assessment of the intrinsic pluripotency of mesoderm-derived stem cells from different niches

Feras Al Battah, J. Bolleyn, T. Vanhaecke, 2012 .

Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ

S. Wölfl, K. Obernier, A. Sachinidis, 2014, Scientific Reports.

Functional Characterization and Gene Expression Profiling of α-Smooth Muscle Actin Expressing Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells

K. Meganathan, J. Hescheler, K. Pfannkuche, 2012, Stem Cell Reviews and Reports.

Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies

D. Spitkovsky, K. Meganathan, J. Hescheler, 2014, Stem Cell Reviews and Reports.

Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives

J. Hescheler, M. Doss, A. Sachinidis, 2017, Scientific Reports.

Cytosine arabinoside induces ectoderm and inhibits mesoderm expression in human embryonic stem cells during multilineage differentiation

V. Wagh, K. Meganathan, A. Sachinidis, 2011, British journal of pharmacology.

Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

Hedi Peterson, Daniel Gerhard, Raivo Kolde, 2012, Archives of Toxicology.

Fam40b is required for lineage commitment of murine embryonic stem cells

V. Wagh, K. Meganathan, J. Hescheler, 2014, Cell Death and Disease.