E. Sjögren

发表

In Vitro Release Mechanisms of Doxorubicin From a Clinical Bead Drug-Delivery System.

P. Hansson, H. Lennernäs, E. Ahnfelt, 2016, Journal of pharmaceutical sciences.

In Vitro Release Mechanisms of Doxorubicin From a Clinical Bead Drug-Delivery System.

P. Hansson, H. Lennernäs, E. Ahnfelt, 2016, Journal of pharmaceutical sciences.

In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models.

Erik Sjögren, Christer Tannergren, Helena Thörn, 2016, Molecular pharmaceutics.

A miniaturized in vitro release method for investigating drug-release mechanisms.

H. Lennernäs, N. Axén, E. Ahnfelt, 2015, International journal of pharmaceutics.

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs.

Christel A. S. Bergström, E. Sjögren, J. Fagerberg, 2015, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Does the Intake of Ethanol Affect Oral Absorption of Poorly Soluble Drugs?

Christel A. S. Bergström, R. Holm, E. Sjögren, 2019, Journal of pharmaceutical sciences.

Drug diffusion in biomimetic hydrogels: importance for drug transport and delivery in non-vascular tumor tissue.

P. Hansson, H. Lennernäs, E. Sjögren, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms.

H. Lennernäs, B. Abrahamsson, E. Sjögren, 2016, Molecular pharmaceutics.

A Physiologically-Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

K. Barnes, J. Tarning, E. Sjögren, 2021, Pharmaceutics.

A Physiologically Based Pharmacokinetic Framework for Prediction of Drug Exposure in Malnourished Children

K. Barnes, J. Tarning, E. Sjögren, 2020 .

Rat intestinal drug permeability: a status report and summary of repeated determinations.

H. Lennernäs, E. Sjögren, D. Dahlgren, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Reply to "Comment on 'In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma'".

H. Lennernäs, M. Hedeland, U. Bondesson, 2018, Molecular pharmaceutics.

Treatment of intermediate stage hepatocellular carcinoma: a review of intrahepatic doxorubicin drug-delivery systems.

H. Lennernäs, N. Axén, E. Ahnfelt, 2014, Therapeutic delivery.

Pulmonary drug absorption and systemic exposure in human: predictions using physiologically based biopharmaceutics modeling.

H. Lennernäs, Helena Thörn, E. Sjögren, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model.

H. Lennernäs, Helena Thörn, E. Sjögren, 2019, Molecular pharmaceutics.

Applications of Physiologically Based Biopharmaceutics Modeling (PBBM) to support Drug Product Quality: A Workshop Summary Report.

Gustavo Mendes Lima Santos, J. Dressman, A. Babiskin, 2020, Journal of pharmaceutical sciences.

Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA.

H. Lennernäs, P. Langguth, E. Sjögren, 2017, Molecular pharmaceutics.

Regional Intestinal Permeability of Three Model Drugs in Human.

H. Lennernäs, B. Abrahamsson, P. Hellström, 2016, Molecular pharmaceutics.

Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report

Amitava Mitra, Nikunjkumar Patel, Filippos Kesisoglou, 2019, The AAPS Journal.

Bryophytes as indicators of environmental factors in forest phytocoenoses

E. Sjögren, 1974 .

Vascular plant communities of Madeira

E. Sjögren, 1972 .

Bryophyte flora and vegetation on the island of Corvo (Azores)

E. Sjögren, 1993 .

Online capillary solid phase extraction and liquid chromatographic separation with quantitative tandem mass spectrometric detection (SPE-LC-MS/MS) of ximelagatran and its metabolites in a complex matrix.

J. Bergquist, H. Lennernäs, P. Sjöberg, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Single bead investigation of a clinical drug delivery system – A novel release mechanism

P. Hansson, H. Lennernäs, E. Ahnfelt, 2018, Journal of controlled release : official journal of the Controlled Release Society.

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: application of the mechanistic absorption model GI-Sim.

Erik Sjögren, Hans Lennernäs, Bertil Abrahamsson, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Talia Flanagan, Clive G. Wilson, Mai Anh Nguyen, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Mechanistic modelling of intestinal drug absorption – The in vivo effects of nanoparticles, hydrodynamics, and colloidal structures

H. Lennernäs, J. Westergren, E. Sjögren, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

PBPK models for the prediction of in vivo performance of oral dosage forms.

Martin Bergstrand, Xavier Pepin, Erik Sjögren, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Reversed-phase ion-pair chromatography with UV-absorbing ions in the mobile phase

E. Sjögren, G. Schill, M. Denkert, 1981 .

Combining in vitro and in silico methods for better prediction of surfactant effects on the absorption of poorly water soluble drugs-a fenofibrate case example.

B. Abrahamsson, A. Müllertz, R. Holm, 2014, International journal of pharmaceutics.

The Multiple Depletion Curves Method Provides Accurate Estimates of Intrinsic Clearance (CLint), Maximum Velocity of the Metabolic Reaction (Vmax), and Michaelis Constant (Km): Accuracy and Robustness Evaluated through Experimental Data and Monte Carlo Simulations

H. Lennernäs, U. Bredberg, T. Andersson, 2009, Drug Metabolism and Disposition.

Direct In Vivo Human Intestinal Permeability (Peff ) Determined with Different Clinical Perfusion and Intubation Methods.

Erik Sjögren, Hans Lennernäs, H. Lennernäs, 2015, Journal of pharmaceutical sciences.

Correction to: Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption

H. Lennernäs, Helena Thörn, E. Sjögren, 2020, The AAPS Journal.

Drug Absorption Parameters Obtained Using the Isolated Perfused Rat Lung Model Are Predictive of Rat In Vivo Lung Absorption

H. Lennernäs, Helena Thörn, E. Sjögren, 2020, The AAPS Journal.

The effects of three absorption‐modifying critical excipients on the in vivo intestinal absorption of six model compounds in rats and dogs

H. Lennernäs, P. Langguth, E. Sjögren, 2018, International journal of pharmaceutics.

Binding processes determine the stereoselective intestinal and hepatic extraction of verapamil in vivo.

H. Lennernäs, Helena Thörn, P. Dickinson, 2012, Molecular pharmaceutics.

The effects of lipiodol and cyclosporin A on the hepatobiliary disposition of doxorubicin in pigs.

H. Lennernäs, M. Hedeland, U. Bondesson, 2014, Molecular pharmaceutics.

Liver Cancer Cell Lines Treated with Doxorubicin under Normoxia and Hypoxia: Cell Viability and Oncologic Protein Profile

F. Heindryckx, H. Lennernäs, E. Sjögren, 2019, Cancers.

Clinical testing of three novel transient receptor potential cation channel subfamily V member 1 antagonists in a pharmacodynamic intradermal capsaicin model

M. Segerdahl, E. Sjögren, O. Stålberg, 2018, European journal of pain.

The pharmacokinetics and hepatic disposition of repaglinide in pigs: mechanistic modeling of metabolism and transport.

H. Lennernäs, U. Bredberg, E. Sjögren, 2012, Molecular pharmaceutics.

Evaluation of drug permeability calculation based on luminal disappearance and plasma appearance in the rat single-pass intestinal perfusion model.

H. Lennernäs, E. Sjögren, C. Tannergren, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Six years of progress in the oral biopharmaceutics area - a summary from the IMI OrBiTo project.

H Lennernäs, A Lindahl, E Sjögren, 2020, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Jejunal absorption of aprepitant from nanosuspensions: Role of particle size, prandial state and mucus layer

H. Lennernäs, M. Hedeland, E. Sjögren, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Distribution of Azorean bryophytes up to 1999, their island distribution and information on their presence elsewhere, including Madeira and the Canary Islands

E. Sjögren, 2001 .

Study protocol for locoregional precision treatment of hepatocellular carcinoma with transarterial chemoembolisation (TACTida), a clinical study: idarubicin dose selection, tissue response and survival

F. Heindryckx, H. Lennernäs, M. Hedeland, 2022, BMJ Open.

The effect of intradermal microdosing of a transient receptor potential cation channel subfamily V member 1 antagonist on heat evoked pain and thermal thresholds in normal and ultraviolet‐C exposed skin in healthy volunteers

L. Ståhle, E. Sjögren, H. Quiding, 2019, European journal of pain.

Preclinical characterization of three transient receptor potential vanilloid receptor 1 antagonists for early use in human intradermal microdose analgesic studies

E. Sjögren, E. Sjögren, M.M. Halldin, 2018, European journal of pain.

In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma

F. Heindryckx, H. Lennernäs, D. Balgoma, 2021, Cells.

Azorean bryophyte communities - a revision of differential species

E. Sjögren, 2003 .

Effect of absorption‐modifying excipients, hypotonicity, and enteric neural activity in an in vivo model for small intestinal transport

H. Lennernäs, E. Sjögren, C. Tannergren, 2018, International journal of pharmaceutics.

Plant cover on the limestone Alvar of Öland : ecology, sociology, taxonomy

E. Sjögren, 1988 .

Assessment of Free Drug Concentration in Cyclodextrin Formulations Is Essential to Determine Drug Potency in Functional In Vitro Assays.

E. Sjögren, Sara B E Andersson, O. Stålberg, 2016, Journal of pharmaceutical sciences.

A Model-Based Approach To Assessing the Importance of Intracellular Binding Sites in Doxorubicin Disposition.

H. Lennernäs, E. Sjögren, I. Dubbelboer, 2017, Molecular pharmaceutics.

Intestinal absorption of BCS class II drugs administered as nanoparticles: A review based on in vivo data from intestinal perfusion models

H. Lennernäs, E. Sjögren, D. Dahlgren, 2020, ADMET & DMPK.

Open Systems Pharmacology Community—An Open Access, Open Source, Open Science Approach to Modeling and Simulation in Pharmaceutical Sciences

Stephan Schmidt, Erik Sjögren, Juri Solodenko, 2019, CPT: pharmacometrics & systems pharmacology.

Optimized Experimental Design for the Estimation of Enzyme Kinetic Parameters: An Experimental Evaluation

Erik Sjögren, Petter Svanberg, E. Sjögren, 2012, Drug Metabolism and Disposition.

Porcine and Human In Vivo Simulations for Doxorubicin-Containing Formulations Used in Locoregional Hepatocellular Carcinoma Treatment

H. Lennernäs, E. Sjögren, I. Dubbelboer, 2018, The AAPS Journal.

In Vivo Drug Delivery Performance of Lipiodol-Based Emulsion or Drug-Eluting Beads in Patients with Hepatocellular Carcinoma.

H. Lennernäs, M. Hedeland, U. Bondesson, 2017, Molecular pharmaceutics.

Hepatic Disposition of Ximelagatran and Its Metabolites in Pig; Prediction of the Impact of Membrane Transporters Through a Simple Disposition Model

J. Bergquist, H. Lennernäs, U. Bredberg, 2010, Pharmaceutical Research.

Effects of absorption-modifying excipients on jejunal drug absorption in simulated fasted and fed luminal conditions.

H. Lennernäs, M. Hedeland, E. Sjögren, 2019, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugs.

E. Sjögren, C. Hilgendorf, Charlotta Vedin, 2016, International journal of pharmaceutics.

Does the choice of applied physiologically‐based pharmacokinetics platform matter? A case study on simvastatin disposition and drug–drug interaction

H. Lennernäs, E. Sjögren, C. Ahlström, 2022, CPT: pharmacometrics & systems pharmacology.

Human in vivo regional intestinal permeability: quantitation using site-specific drug absorption data.

Erik Sjögren, Hans Lennernäs, H. Lennernäs, 2015, Molecular pharmaceutics.

Dissolution and Translational Modeling Strategies Toward Establishing an In Vitro-In Vivo Link—a Workshop Summary Report

N. Patel, T. Heimbach, E. Tsakalozou, 2019, The AAPS Journal.

In Vivo Predictive Dissolution (IPD) and Biopharmaceutical Modeling and Simulation: Future Use of Modern Approaches and Methodologies in a Regulatory Context.

H Lennernäs, A Lindahl, A Van Peer, 2017, Molecular pharmaceutics.

Applications of Clinically Relevant Dissolution Testing: Workshop Summary Report

Andreas M. Abend, Nagesh T. Bandi, P. Marroum, 2018, The AAPS Journal.

Epiphyllous bryophytes in the Azores Islands

E. Sjögren, 1997 .

In Vitro Biopredictive Methods: A Workshop Summary Report.

Amitava Mitra, Sandra Suarez-Sharp, Erik Sjögren, 2020, Journal of pharmaceutical sciences.

Reply to "Comment on 'In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically Based Absorption Models'".

Erik Sjögren, Christer Tannergren, Helena Thörn, 2017, Molecular pharmaceutics.

Bryophytes (Musci) unexpectedly rare or absent in the Azores.

E. Sjögren, 2006 .

Physiological based pharmacokinetic and biopharmaceutics modelling of subcutaneously administered compounds - an overview of in silico models.

E. Sjögren, I. Dubbelboer, 2022, International journal of pharmaceutics.

Pulmonary absorption – estimation of effective pulmonary permeability and tissue retention of ten drugs using an ex vivo rat model and computational analysis

H. Lennernäs, Helena Thörn, E. Sjögren, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Pharmacokinetics of an injectable modified-release 2-hydroxyflutamide formulation in the human prostate gland using a semiphysiologically based biopharmaceutical model.

T. Tammela, H. Lennernäs, N. Axén, 2014, Molecular pharmaceutics.

Lipiodol does not affect the tissue distribution of intravenous doxorubicin infusion in pigs

H. Lennernäs, E. Sjögren, I. Dubbelboer, 2017, The Journal of pharmacy and pharmacology.

Lipiodol-based emulsions used for transarterial chemoembolization and drug delivery: Effects of composition on stability and product quality

P. Hansson, H. Lennernäs, E. Ahnfelt, 2019, Journal of Drug Delivery Science and Technology.

Regional Intestinal Permeability in Rats: A Comparison of Methods.

H. Lennernäs, B. Abrahamsson, E. Sjögren, 2017, Molecular pharmaceutics.

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations.

H. Lennernäs, B. Abrahamsson, J. Westergren, 2017, Molecular pharmaceutics.

Effects of verapamil on the pharmacokinetics and hepatobiliary disposition of fexofenadine in pigs.

H. Lennernäs, M. Hedeland, U. Bondesson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Overview of authorized drug products for subcutaneous administration: pharmaceutical, therapeutic, and physicochemical properties.

E. Sjögren, I. Dubbelboer, 2022, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Clive G. Wilson, A. Peer, H. Lennernäs, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Understanding Statin‐Roxadustat Drug–Drug‐Disease Interaction Using Physiologically‐Based Pharmacokinetic Modeling

M. Någård, E. Sjögren, Anna Vildhede, 2023, Clinical pharmacology and therapeutics.