S. Klimuk

发表

Lipid-based formulations of antisense oligonucleotides for systemic delivery applications.

M. Hope, S. Semple, S. Klimuk, 2000, Methods in enzymology.

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures.

P. Cullis, N. Maurer, M. Hope, 2001, Biochimica et biophysica acta.

Rational design of cationic lipids for siRNA delivery

K. G. Rajeev, M. Manoharan, A. Akinc, 2010, Nature Biotechnology.

Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity.

K. Edwards, P. Cullis, N. Maurer, 2005, Journal of pharmaceutical sciences.

Enhanced anti-inflammatory activity of a liposomal intercellular adhesion molecule-1 antisense oligodeoxynucleotide in an acute model of contact hypersensitivity.

C. Bennett, M. Hope, P. Scherrer, 2000, The Journal of pharmacology and experimental therapeutics.

Immunogenicity and Rapid Blood Clearance of Liposomes Containing Polyethylene Glycol-Lipid Conjugates and Nucleic Acid

M. Hope, S. Semple, S. Ansell, 2005, Journal of Pharmacology and Experimental Therapeutics.

Epicutaneous application of CpG oligodeoxynucleotides with peptide or protein antigen promotes the generation of CTL.

S. Semple, S. Klimuk, J. Dutz, 2004, The Journal of investigative dermatology.

Cholesterol mobilization and regression of atheroma in cholesterol-fed rabbits induced by large unilamellar vesicles.

M. Hope, S. Klimuk, P. Pritchard, 1998, Biochimica et biophysica acta.

Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations.

M. Johnston, K. Edwards, P. Cullis, 2006, Biochimica et biophysica acta.

Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN

P. Cullis, Ying K. Tam, S. Semple, 2007, Cancer Immunology, Immunotherapy.

Contact hypersensitivity: a simple model for the characterization of disease-site targeting by liposomes.

M. Hope, P. Scherrer, S. Semple, 1999, Biochimica et biophysica acta.

Lipid-Based Carriers for the Systemic Delivery of Antisense Drugs

M. Hope, S. Semple, M. Webb, 1999 .

Abstract 2829: Preclinical characterization of TKM-080301, a lipid nanoparticle formulation of a small interfering RNA directed against polo-like kinase 1

A. Judge, K. Mcclintock, I. Maclachlan, 2011 .

Liposome encapsulation enhances the anti-inflammatory activity of an ICAM-1 antisense oligonucleotide

S. Klimuk, 2000 .

Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin.

Norbert Maurer, M. Johnston, P. Cullis, 2007, Biochimica et biophysica acta.

Transbilayer movement and net flux of cholesterol and cholesterol sulfate between liposomal membranes.

M. Hope, S. Klimuk, W. Rodrigueza, 1995, Biochemistry.