G. Fan

发表

Macrophage inflammatory protein 2 inhibits beta-amyloid peptide (1-42)-mediated hippocampal neuronal apoptosis through activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling pathways.

K. Watson, G. Fan, 2005, Molecular pharmacology.

The chemotaxis of M1 and M2 macrophages is regulated by different chemokines

S. Xiong, B. Zheng, G. Fan, 2015, Journal of leukocyte biology.

Lentiviral-mediated knock-down of GD3 synthase protects against MPTP-induced motor deficits and neurodegeneration

D. Heck, M. P. McDonald, G. Fan, 2019, Neuroscience Letters.

Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer’s disease

R. Bucala, R. Ye, G. Fan, 2015, Journal of Neuroinflammation.

Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis.

A. Richmond, L. Lapierre, J. Goldenring, 2004, Molecular biology of the cell.

Deubiquitination of CXCR4 by USP14 Is Critical for Both CXCL12-induced CXCR4 Degradation and Chemotaxis but Not ERK Activation

L. Limbird, G. Fan, Marjelo A. Mines, 2009, Journal of Biological Chemistry.

Chemokine receptor internalization and intracellular trafficking.

A. Richmond, J. Sai, E. Schutyser, 2005, Cytokine & growth factor reviews.

Roles of resolvins in the resolution of acute inflammation

G. Fan, Wenjuan Xuan, Q. Qu, 2015, Cell biology international.

Hsc/Hsp70 Interacting Protein (Hip) Associates with CXCR2 and Regulates the Receptor Signaling and Trafficking*

Wei Yang, A. Richmond, J. Sai, 2002, The Journal of Biological Chemistry.

Phosphorylation-independent Association of CXCR2 with the Protein Phosphatase 2A Core Enzyme*

Wei Yang, A. Richmond, J. Sai, 2001, The Journal of Biological Chemistry.

Differential regulation of CXCR2 trafficking by Rab GTPases.

A. Richmond, L. Lapierre, J. Goldenring, 2003, Blood.

Chemokine CXCL12 Induces Binding of Ferritin Heavy Chain to the Chemokine Receptor CXCR4, Alters CXCR4 Signaling, and Induces Phosphorylation and Nuclear Translocation of Ferritin Heavy Chain*

Jingwu Z. Zhang, Runsheng Li, G. Fan, 2006, Journal of Biological Chemistry.

Chemokines, macrophage inflammatory protein-2 and stromal cell-derived factor-1α, suppress amyloid β-induced neurotoxicity.

R. Splittgerber, A. Richmond, D. Milatović, 2011, Toxicology and applied pharmacology.

Functional expression of opioid receptor-like receptor and its endogenous specific agonist nociceptin/orphanin FQ during mouse embryogenesis

G. Pei, G. Fan, Yi Zhang, 1997, Cell Research.

Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice.

M. Lohse, Y. Grimmer, S. Engelhardt, 2001, Molecular pharmacology.

Discovery of 2-[5-(4-Fluorophenylcarbamoyl)pyridin-2-ylsulfanylmethyl]phenylboronic Acid (SX-517): Noncompetitive Boronic Acid Antagonist of CXCR1 and CXCR2

A. Schuler, G. Fan, W. Wicomb, 2014, Journal of medicinal chemistry.

Macrophage Inflammatory Protein 2 Inhibits (cid:1) -Amyloid Peptide (1-42)-Mediated Hippocampal Neuronal Apoptosis through Activation of Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Signaling Pathways

G. Fan, Kurt Watson, 2005 .

The 73-kDa Heat Shock Cognate Protein Is a CXCR4 Binding Protein that Regulates the Receptor Endocytosis and the Receptor-Mediated Chemotaxis

Ningli Li, Sunxi Wang, G. Fan, 2006, Molecular Pharmacology.

Endogenous opioid receptor‐like receptor in human neuroblastoma SK‐N‐SH cells: activation of inhibitory G protein and homologous desensitization

Zhi-jie Cheng, G. Pei, G. Fan, 1997, Neuroreport.

Activation of CXCR4 Triggers Ubiquitination and Down-regulation of Major Histocompatibility Complex Class I (MHC-I) on Epithelioid Carcinoma HeLa Cells*

Jingwu Z. Zhang, G. Fan, Ziqing Wang, 2008, Journal of Biological Chemistry.

Cyclophilin A Is Required for CXCR4-mediated Nuclear Export of Heterogeneous Nuclear Ribonucleoprotein A2, Activation and Nuclear Translocation of ERK1/2, and Chemotactic Cell Migration*

Jingwu Z. Zhang, Runsheng Li, G. Fan, 2008, Journal of Biological Chemistry.

Identification of a motif in the carboxyl terminus of CXCR2 that is involved in adaptin 2 binding and receptor internalization.

A. Richmond, X. Wang, W. Yang, 2001, Biochemistry.

Suppression of phospholipase C blocks Gi-mediated inhibition of adenylyl cyclase activity.

G. Pei, G. Fan, W. Zhang, 1998, European journal of pharmacology.

Plectin regulates the signaling and trafficking of the HIV-1 co-receptor CXCR4 and plays a role in HIV-1 infection.

Jingwu Z. Zhang, G. Fan, J. S. Goodwin, 2008, Experimental cell research.

The many roles of chemokine receptors in neurodegenerative disorders: emerging new therapeutical strategies.

G. Fan, Yun Ding, Marjelo A. Mines, 2007, Current medicinal chemistry.

Modulation by calcium/calmodulin-dependent protein kinase II of functional response of delta opioid receptor in neuroblastoma x glioma hybrid (NG108-15) cells

G. Pei, G. Fan, W. Zhang, 1997, Neuropharmacology.

Constitutive Activity of the Human β1-Adrenergic Receptor in β1-Receptor Transgenic Mice

M. Lohse, Y. Grimmer, S. Engelhardt, 2001 .

N-Methyl-D-aspartate attenuates opioid receptor-mediated G protein activation and this process involves protein kinase C.

L. Ma, G. Pei, G. Fan, 1998, Molecular pharmacology.

Protein Phosphatase 2A Interacts with and Directly Dephosphorylates RelA*

B. Wadzinski, A. Richmond, G. Fan, 2001, The Journal of Biological Chemistry.

Activation of N-methyl-D-aspartate receptor attenuates acute responsiveness of delta-opioid receptors.

L. Ma, G. Pei, G. Fan, 1997, Molecular pharmacology.

Characterization of Gene Expression Phenotype in Amyotrophic Lateral Sclerosis Monocytes

Shanker Kalyana-Sundaram, G. P. Livi, D. Sieglaff, 2017, JAMA neurology.

CXCL1 Triggers Caspase-3 Dependent Tau Cleavage in Long-Term Neuronal Cultures and in the Hippocampus of Aged Mice: Implications in Alzheimer's Disease.

G. Fan, Run-sheng Li, Shunwei Zhu, 2015, Journal of Alzheimer's disease : JAD.

Inhibition of calcium/calmodulin-dependent protein kinase II in rat hippocampus attenuates morphine tolerance and dependence.

L. Ma, G. Fan, L. Wang, 1999, Molecular pharmacology.

CXCL12 Induces Tyrosine Phosphorylation of Cortactin, Which Plays a Role in CXC Chemokine Receptor 4-mediated Extracellular Signal-regulated Kinase Activation and Chemotaxis*

Jingwu Z. Zhang, G. Fan, H. Pan, 2006, Journal of Biological Chemistry.

Retinoic Acid Attenuates β-Amyloid Deposition and Rescues Memory Deficits in an Alzheimer's Disease Transgenic Mouse Model

M. Block, M. P. McDonald, G. Fan, 2008, The Journal of Neuroscience.

Indirubin-3'-monoxime rescues spatial memory deficits and attenuates β-amyloid-associated neuropathology in a mouse model of Alzheimer's disease

G. Fan, Yun Ding, A. Qiao, 2010, Neurobiology of Disease.

N-Methyl-d-aspartate Attenuates CXCR2-Mediated Neuroprotection through Enhancing the Receptor Phosphorylation and Blocking the Receptor Recycling

Jingwu Z. Zhang, G. Fan, Qingwei Luo, 2005, Molecular Pharmacology.

The C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxis

A. Richmond, J. Sai, D. Wang, 2004, Journal of Cell Science.

Discovery of a Potent and Selective CCR8 Small Molecular Antagonist IPG7236 for the Treatment of Cancer.

Yuehua Wu, G. Fan, Zheng Li, 2023, Journal of medicinal chemistry.

Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer’s disease

R. Bucala, R. Ye, G. Fan, 2015, Journal of Neuroinflammation.

Macrophage Inflammatory Protein 2 Inhibits β-Amyloid Peptide (1-42)-Mediated Hippocampal Neuronal Apoptosis through Activation of Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Signaling Pathways

G. Fan, Kurt Watson, 2005, Molecular Pharmacology.

Inhibition of phospholipase C blocks opioid receptor‐mediated activation of Gi proteins

G. Pei, G. Fan, Yalan Wu, 1998, Neuroreport.

How do chemokine/chemokine receptor activations affect tumorigenesis?

P. Dhawan, A. Richmond, G. Fan, 2004, Novartis Foundation symposium.