Masakazu Inazuka

Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.

Yuta Tanaka, T. Kawamoto, T. Ishikawa, 2013, Journal of medicinal chemistry.

Antitumor Activity and Pharmacodynamic Biomarkers of a Novel and Orally Available Small-Molecule Antagonist of Inhibitor of Apoptosis Proteins

M. Yabuki, Sei Yoshida, T. Ishikawa, 2012, Molecular Cancer Therapeutics.

ATM mutations in patients with ataxia telangiectasia screened by a hierarchical strategy

T. Tahira, Y. Kukita, O. Nikaido, 1998, Human mutation.

Discovery of Brain-Penetrant Glucosylceramide Synthase Inhibitors with a Novel Pharmacophore.

H. Oki, T. Ohashi, Yuta Tanaka, 2022, Journal of medicinal chemistry.

T-3256336, a novel and orally available small molecule IAP antagonist, induced tumor cell death via induction of systemic TNF alpha production.

M. Yabuki, Sei Yoshida, T. Ishikawa, 2016, Biochemical and biophysical research communications.

An inhibitor of apoptosis protein antagonist T-3256336 potentiates the antitumor efficacy of the Nedd8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924).

Peter G. Smith, M. Yabuki, Sei Yoshida, 2016, Biochemical and biophysical research communications.

A streamlined mutation detection system: multicolor post-PCR fluorescence labeling and single-strand conformational polymorphism analysis by capillary electrophoresis.

T. Tahira, H. Wenz, K. Hayashi, 1997, Genome research.