Kasey L. Rivas

发表

Biochemical Screening of Five Protein Kinases from Plasmodium falciparum against 14,000 Cell-Active Compounds

Gregory J. Crowther, Dustin J Maly, G. Drewes, 2016, PloS one.

Structurally simple farnesyltransferase inhibitors arrest the growth of malaria parasites.

D. Chakrabarti, F. Buckner, C. Verlinde, 2005, Angewandte Chemie.

Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis.

Dustin J Maly, W. V. Van Voorhis, K. Ojo, 2016, The Journal of infectious diseases.

Structurally simple, potent, Plasmodium selective farnesyltransferase inhibitors that arrest the growth of malaria parasites.

D. Chakrabarti, F. Buckner, S. Fletcher, 2006, Journal of medicinal chemistry.

2-Oxo-tetrahydro-1,8-naphthyridines as selective inhibitors of malarial protein farnesyltransferase and as anti-malarials.

D. Chakrabarti, M. Gelb, C. Verlinde, 2008, Bioorganic & medicinal chemistry letters.

Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy

Dustin J Maly, B. Striepen, A. White, 2017, The Journal of infectious diseases.

Development of an Orally Available and Central Nervous System (CNS) Penetrant Toxoplasma gondii Calcium-Dependent Protein Kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-a-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis.

Dustin J Maly, W. Hol, M. Parsons, 2016, Journal of medicinal chemistry.

SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1

Dustin J Maly, W. Hol, M. Parsons, 2015, ACS medicinal chemistry letters.

Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis.

Dustin J Maly, M. Parsons, A. DeRocher, 2018, The Journal of infectious diseases.

Development of 5-Aminopyrazole-4-carboxamide-based Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy.

R. Hackman, W. V. Van Voorhis, K. Ojo, 2019, Journal of medicinal chemistry.

Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis.

Dustin J Maly, D. Kempf, Joachim Müller, 2017, International journal for parasitology.

A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.

Dustin J Maly, X. Su, K. Comess, 2014, The Journal of infectious diseases.

Speci fi c Inhibitor of Pf CDPK 4 Blocks Malaria Transmission : Chemical-genetic Validation

X. Su, K. Comess, W. V. Voorhis, 2013 .

A novel calcium-dependent protein kinase inhibitor as a lead compound for treating cryptosporidiosis.

Dustin J Maly, A. White, W. V. Van Voorhis, 2013, The Journal of infectious diseases.

Safety and efficacy of the bumped kinase inhibitor BKI-1553 in pregnant sheep experimentally infected with Neospora caninum tachyzoites

J. Benavides, W. V. Van Voorhis, K. Ojo, 2018, International journal for parasitology. Drugs and drug resistance.

Protein farnesyltransferase inhibitors exhibit potent antimalarial activity.

David K Williams, Patricia C Weber, D. Chakrabarti, 2005, Journal of medicinal chemistry.

Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase

David W. Gray, K. Read, I. Gilbert, 2016, ACS infectious diseases.

Efficacy, Pharmacokinetics, and Metabolism of Tetrahydroquinoline Inhibitors of Plasmodium falciparum Protein Farnesyltransferase

D. Chakrabarti, M. Gelb, F. Buckner, 2007, Antimicrobial Agents and Chemotherapy.

Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.

Steven Fletcher, M. Gelb, L. Beese, 2009, Chemistry & biology.

Potent, Plasmodium-selective farnesyltransferase inhibitors that arrest the growth of malaria parasites: structure-activity relationships of ethylenediamine-analogue scaffolds and homology model validation.

William P. Katt, D. Chakrabarti, M. Gelb, 2008, Journal of medicinal chemistry.

Novel paradigms for drug discovery: computational multitarget screening.

Ram Samudrala, Ekachai Jenwitheesuk, Jeremy A Horst, 2008, Trends in pharmacological sciences.

Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials.

D. Chakrabarti, M. Gelb, F. Buckner, 2007, Journal of medicinal chemistry.

A Noncoding RNA Antisense to Moesin at 5p14.1 in Autism

G. Coetzee, Kasey L. Rivas, T. Kerin, 2012, Science Translational Medicine.

A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice.

W. V. Van Voorhis, K. Ojo, Kasey L. Rivas, 2016, The Journal of infectious diseases.

Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold.

Dustin J Maly, K. Comess, C. Verlinde, 2014, ACS medicinal chemistry letters.

Selective inhibition of Sarcocystis neurona calcium-dependent protein kinase 1 for equine protozoal myeloencephalitis therapy.

Dustin J Maly, M. Parsons, S. Dangoudoubiyam, 2016, International journal for parasitology.

2-Oxotetrahydroquinoline-based antimalarials with high potency and metabolic stability.

M. Gelb, C. Verlinde, W. V. Van Voorhis, 2008, Journal of medicinal chemistry.

A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.

Dustin J Maly, X. Su, K. Comess, 2014, The Journal of infectious diseases.

Second generation tetrahydroquinoline-based protein farnesyltransferase inhibitors as antimalarials.

D. Chakrabarti, F. Buckner, C. Verlinde, 2007, Journal of medicinal chemistry.

A Noncoding RNA Antisense to Moesin at 5p14.1 in Autism

G. Coetzee, Kasey L. Rivas, T. Kerin, 2012, Science Translational Medicine.