Linli Li

发表

Discovery and structure-activity relationship studies of 1-aryl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-dione derivatives as potent dual inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1) and trytophan 2,3-dioxygenase (TDO).

Sheng-yong Yang, Shulei Pan, Yangli Zhou, 2020, European journal of medicinal chemistry.

Cerebrospinal Fluid Pulsation Stress Promotes the Angiogenesis of Tissue-Engineered Laminae

Feizhou Lyu, Linli Li, Yiqun He, 2020, Stem cells international.

The Role of Continuous Cerebrospinal Fluid Pulsation Stress in the Remodeling of Artificial Vertebral Laminae: A Comparison Experiment.

Linli Li, Yiqun He, Youhai Dong, 2019, Tissue engineering. Part A.

Scaffold-Free Spheroids with Two-Dimensional Heteronano-Layers (2DHNL) Enabling Stem Cell and Osteogenic Factor Codelivery for Bone Repair.

A. Terzic, Lichun Lu, B. Elder, 2022, ACS nano.

Photoelectrochemical properties of TiO2/g-C3N4 composited electrodes fabricated by a co-electrodeposited method

Yuan Yang, Linli Li, Xiaoxing Fan, 2021 .

Preclinical pharmacodynamic evaluation of a new Src/FOSL1 inhibitor, LY‐1816, in pancreatic ductal adenocarcinoma

L. Zhong, Sheng-yong Yang, Jun Zou, 2019, Cancer science.

Mesenchymal Stem Cells and Their Small Extracellular Vesicles as Crucial Immunological Efficacy for Hepatic Diseases

Linli Li, Wenrong Xu, Jiajia Jiang, 2022, Frontiers in Immunology.

Injectable Electrical Conductive and Phosphate Releasing Gel with Two-Dimensional Black Phosphorus and Carbon Nanotubes for Bone Tissue Engineering.

Lichun Lu, Linli Li, Matthew N George, 2020, ACS biomaterials science & engineering.

Wnt/β-Catenin Pathway Balances Scaffold Degradation and Bone Formation in Tissue-Engineered Laminae

Aolei Yang, Feizhou Lyu, Linli Li, 2021, Stem cells international.

Cervinomycins C1-4 with cytotoxic and antibacterial activity from Streptomyces sp. CPCC 204980

Xuefu You, Liyan Yu, Linli Li, 2020, The Journal of Antibiotics.

Discovery of benzo[d]oxazol-2(3H)-one derivatives as a new class of TNIK inhibitors for the treatment of colorectal cancer.

Linli Li, Shengyong Yang, Xin Luo, 2022, Bioorganic & medicinal chemistry letters.

Preclinical pharmacodynamic evaluation of drug candidate SKLB-178 in the treatment of non-small cell lung cancer

Yiguo Hu, Xin Chen, L. Zhong, 2017, Oncotarget.

Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5.

Yan Fan, R. Xiang, Yinping Guo, 2022, European journal of medicinal chemistry.

PDGF-D prodomain differentially inhibits the biological activities of PDGF-D and PDGF-B.

Dan Wu, Linli Li, L. Mi, 2022, Journal of molecular biology.

Identification of triazolopyridine derivatives as a new class of AhR agonists and evaluation of anti-psoriasis effect in a mouse model.

Shengyong Yang, Chenyu Tian, Linli Li, 2022, European journal of medicinal chemistry.

Α-MMC and MAP30, two ribosome-inactivating proteins extracted from Momordica charantia, induce cell cycle arrest and apoptosis in A549 human lung carcinoma cells.

Yao Meng, Y. Meng, Linli Li, 2015, Molecular medicine reports.

Identification of 5-(2,3-Dihydro-1 H-indol-5-yl)-7 H-pyrrolo[2,3- d]pyrimidin-4-amine Derivatives as a New Class of Receptor-Interacting Protein Kinase 1 (RIPK1) Inhibitors, Which Showed Potent Activity in a Tumor Metastasis Model.

Sheng-yong Yang, Lijuan Chen, Luyi Huang, 2018, Journal of medicinal chemistry.

The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression

Yuquan Wei, Shile Huang, Yiguo Hu, 2019, Cell Death & Differentiation.

Tailored Extracellular Vesicles: Novel Tool for Tissue Regeneration

Linli Li, H. Qian, Wenrong Xu, 2022, Stem cells international.

Exosomes: Emerging Therapy Delivery Tools and Biomarkers for Kidney Diseases

Linli Li, H. Qian, Wenrong Xu, 2021, Stem cells international.

Exosomal MMP2 derived from mature osteoblasts promotes angiogenesis of endothelial cells via VEGF/Erk1/2 signaling pathway.

Feizhou Lyu, Linli Li, Yiqun He, 2019, Experimental cell research.

Neutrophil membrane engineered HucMSC sEVs alleviate cisplatin-induced AKI by enhancing cellular uptake and targeting

Linli Li, H. Qian, Wenrong Xu, 2022, Journal of Nanobiotechnology.

Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization.

Sheng-yong Yang, Yinping Guo, Yangli Zhou, 2021, Biochemical and biophysical research communications.

Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.

Shanshan Zhang, Shengyong Yang, J. Nan, 2022, European journal of medicinal chemistry.

Isarubrolones Containing a Pyridooxazinium Unit from Streptomyces as Autophagy Activators.

Xuefu You, Liyan Yu, Linli Li, 2019, Journal of natural products.

Large-Scale Preparation of g-C3N4 Porous Nanotubes with Enhanced Photocatalytic Activity by Using Salicylic Acid and Melamine

Xiangxiang Cheng, Linli Li, Xiaoxing Fan, 2020 .

Discovery of thieno[2,3-d]pyrimidin-4(3H)-one derivatives as a new class of ROCK inhibitors.

Sheng-yong Yang, J. Nan, Linli Li, 2020, Bioorganic & medicinal chemistry letters.

Discovery of Small Molecule Agonist of Gonadotropin-Releasing Hormone Receptor (GnRH1R)

Yifei Wang, Xin Yang, Yangli Zhou, 2022, J. Chem. Inf. Model..

Zinc-doped hydroxyapatite and poly(propylene fumarate) nanocomposite scaffold for bone tissue engineering

A. Terzic, Lichun Lu, A. Rezaei, 2022, Journal of Materials Science.

SARS-CoV-2 M pro inhibitors with antiviral activity in a transgenic mouse model

Yuquan Wei, Yiguo Hu, Sheng-yong Yang, 2021 .

Discovery of 2-vinyl-10H-phenothiazine derivatives as a class of ferroptosis inhibitors with minimal human Ether-a-go-go Related Gene (hERG) Activity for the treatment of DOX-induced cardiomyopathy.

Linli Li, Wei Yang, Shengyong Yang, 2022, Bioorganic & medicinal chemistry letters.

Discovery of Small Molecule FLT3 Inhibitors That Are Able to Overcome Drug-Resistant Mutations.

Sheng-yong Yang, Yifei Wang, Tianqi Wang, 2020, Bioorganic & medicinal chemistry letters.

3,3′-Diindolylmethane Promotes Gastric Cancer Progression via β-TrCP-Mediated NF-κB Activation in Gastric Cancer-Derived MSCs

Linli Li, H. Qian, Wenrong Xu, 2021, Frontiers in Oncology.

Exosomal let‐7f‐5p derived from mineralized osteoblasts promotes the angiogenesis of endothelial cells via the DUSP1/Erk1/2 signaling pathway

Feizhou Lyu, Linli Li, Yiqun He, 2021, Journal of tissue engineering and regenerative medicine.

Reconstruction of Epidural Fat to Prevent Epidural Fibrosis after Laminectomy in Rabbits.

Linli Li, Yiqun He, Youhai Dong, 2021, Tissue engineering. Part A.

Preparation of K+ doped ZnO nanorods with enhanced photocatalytic performance under visible light

Xiangxiang Cheng, Linli Li, Xiaoxing Fan, 2019, Journal of Physics D: Applied Physics.

K+-Doped ZnO/g-C3N4 Heterojunction: Controllable Preparation, Efficient Charge Separation, and Excellent Photocatalytic VOC Degradation Performance

Xiangxiang Cheng, Linli Li, Xiaoxing Fan, 2021, Industrial & Engineering Chemistry Research.

Co3O4 nanoparticles/Bi2O3 nanosheets: One step synthesis, high-efficiency thermal catalytic performance, and catalytic mechanism research

Lanqin Tang, Linli Li, Xiaoxing Fan, 2022, Molecular Catalysis.

Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor

Jun Zou, Yifei Wang, Xin Yang, 2022, Nature Communications.

SARS-CoV-2 Mpro inhibitors with antiviral activity in a transgenic mouse model

Yuquan Wei, Yiguo Hu, Sheng-yong Yang, 2021, Science.

Isatropolone/isarubrolone Cm from Streptomyces with biological activity of inducing incomplete autophagy

Liyan Yu, Linli Li, Jingpu Zhang, 2022, The Journal of Antibiotics.

Geninthiocins C and D from Streptomyces as 35-membered macrocyclic thiopeptides with modified tail moiety

Xuefu You, Liyan Yu, Linli Li, 2018, The Journal of Antibiotics.

Effect of La2O3 on crystallization of Glass-ceramics

Liping Ma, Linli Li, Dan Zhao, 2020 .

Discovery of 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one derivatives as a new class of ROCK inhibitors for the treatment of glaucoma.

Linli Li, Z. Miao, Y. Zhang, 2021, Bioorganic & medicinal chemistry letters.

Injectable catalyst-free "click" organic-inorganic nanohybrid (click-ON) cement for minimally invasive in vivo bone repair.

A. Terzic, Lichun Lu, M. Yaszemski, 2021, Biomaterials.

Photothermal synergic catalytic degradation of the gaseous organic pollutant isopropanol in oxygen vacancies utilizing ZnFe2O4

Yuan Yang, J. Guan, Linli Li, 2021 .

Wound healing and anti-inflammatory effects of Anethum graveolens extract loaded in PVA fibers: An in vitro and in vivo study

Linli Li, Fengjuan Wang, 2022, Journal of Bioactive and Compatible Polymers.

Cervinomycins C1-4 with cytotoxic and antibacterial activity from Streptomyces sp. CPCC 204980

Xuefu You, Liyan Yu, Linli Li, 2020, The Journal of Antibiotics.

Cytotoxic and Antibacterial Cervinomycins B1-4 from a Streptomyces Species.

Xuefu You, Liyan Yu, Linli Li, 2019, Journal of natural products.

Chemosynthesis and characterization of site-specific N-terminally PEGylated Alpha-momorcharin as apotential agent

Yao Meng, Linli Li, Jinghui Sun, 2018, Scientific Reports.

Discovery of 3,4-Dihydrobenzo[f][1,4]oxazepin-5(2H)-one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects.

Sheng-yong Yang, Chenyu Tian, Linli Li, 2022, Journal of medicinal chemistry.

Calcium Channels: Noteworthy Regulators and Therapeutic Targets in Dermatological Diseases

Linli Li, Hui Shi, Peipei Wu, 2021, Frontiers in Pharmacology.

Structural Optimization and Structure-Activity Relationship Studies of 6,6-Dimethyl-4-(phenylamino)-6H-pyrimido[5,4-b][1,4]oxazin-7(8H)-one Derivatives as A New Class of Potent Inhibitors of Pan-Trk and Their Drug-Resistant Mutants.

Sheng-yong Yang, Chenyu Tian, Tianqi Wang, 2022, Journal of medicinal chemistry.

Isarubrolone C Promotes Autophagic Degradation of Virus Proteins via Activating ATG10S in HepG2 Cells.

Linli Li, Jingpu Zhang, Linzhuan Wu, 2022, Journal of natural products.

Non-classical ferroptosis inhibition by a small molecule targeting PHB2

L. Désaubry, Lunzhi Dai, Chenyu Tian, 2022, Nature Communications.

Biological and Mechanical Factors Promote the Osteogenesis of Rabbit Artificial Vertebral Laminae: A Comparison Study.

Linli Li, Yiqun He, Youhai Dong, 2017, Tissue engineering. Part A.

Treatment of Thoracolumbar Fractures by Percutaneous Pedicle Screw Fixation Technique Combined with Three-step Reduction

Linli Li, Yiqun He, Youhai Dong, 2016, Journal of Neurological Surgery Part A: Central European Neurosugery.

Comparison of Baumgaertner and Chang reduction quality criteria for the assessment of trochanteric fractures

Linli Li, Yiqun He, Youhai Dong, 2019, Bone & joint research.

Improvement of Daptomycin Production in Streptomyces roseosporus through the Acquisition of Pleuromutilin Resistance

Changhua Hu, Qing Liu, Changhua Hu, 2013, BioMed research international.

Discovery of 3-phenyl-1,2,4-oxadiazole derivatives as a new class of SARS-CoV-2 main protease inhibitors

Yifei Wang, Linli Li, Z. Fang, 2023, Bioorganic & Medicinal Chemistry Letters.

Genome-Guided Discovery of Pretilactam from Actinosynnema pretiosum ATCC 31565

Liyan Yu, Linli Li, Bingya Jiang, 2019, Molecules.

Discovery of Potent Small Molecule SIRT6 Activators: Structure-Activity Relationship and Anti-pancreatic Ductal Adenocarcinoma Activity.

Sheng-yong Yang, Linli Li, Hui Li, 2020, Journal of medicinal chemistry.

Fe2O3 nanorods/CuO nanoparticles p-n heterojunction photoanode: Effective charge separation and enhanced photoelectrochemical properties.

Ran Tao, Linli Li, Xiaoxing Fan, 2021, Journal of colloid and interface science.

Discovery of human TyrRS inhibitors by structure-based virtual screening, structural optimization, and bioassays

Sheng-yong Yang, R. Xiang, Linli Li, 2019, RSC advances.

3D-Printed Scaffolds with Carbon Nanotubes for Bone Tissue Engineering: Fast and Homogeneous One-Step Functionalization.

A. Terzic, Lichun Lu, M. Yaszemski, 2020, Acta biomaterialia.

Discovery of 6,7-dihydro-5H-pyrrolo[3,4-d] pyrimidine derivatives as a new class of ATR inhibitors.

Yinping Guo, Linli Li, Yan Jiao, 2022, Bioorganic & medicinal chemistry letters.

Discovery of a potent and highly selective inhibitor of ataxia telangiectasia mutated and Rad3-Related (ATR) kinase: Structural activity relationship and antitumor activity both in vitro and in vivo.

Qiao Huang, J. Nan, Linli Li, 2022, European journal of medicinal chemistry.

Mesenchymal stem cell spheroids incorporated with collagen and black phosphorus promote osteogenesis of biodegradable hydrogels.

Lichun Lu, Linli Li, Xifeng Liu, 2021, Materials science & engineering. C, Materials for biological applications.

Cyclic pulsation stress promotes bone formation of tissue engineered laminae through the F-actin/YAP-1/β-Catenin signaling axis

Feizhou Lyu, Linli Li, Yiqun He, 2021, npj Regenerative Medicine.

Discovery of JMJD7 inhibitors with the aid of virtual screening and bioactivity evaluation.

Tianqi Wang, Linli Li, Wenqing Zhang, 2021, Bioorganic & medicinal chemistry letters.

Biomimetic Electrospun PLLA/PPSB Nanofibrous Scaffold Combined with Human Neural Stem Cells for Spinal Cord Injury Repair

Weizhong Wang, Xiaojun Zhou, Feizhou Lyu, 2023, ACS Applied Nano Materials.

HucMSC exosome-delivered 14-3-3ζ alleviates ultraviolet radiation-induced photodamage via SIRT1 pathway modulation

Linli Li, H. Qian, Wenrong Xu, 2021, Aging.

Cyclic pulsation stress promotes bone formation of tissue engineered laminae through the F-actin/YAP-1/β-Catenin signaling axis

Feizhou Lyu, Linli Li, Yiqun He, 2021, NPJ Regenerative medicine.

SDF-1α/OPF/BP Composites Enhance the Migrating and Osteogenic Abilities of Mesenchymal Stem Cells

A. Terzic, Lichun Lu, Linli Li, 2021, Stem Cells International.

Structure-activity relationship studies of phenothiazine derivatives as a new class of ferroptosis inhibitors together with the therapeutic effect in an ischemic stroke model.

Sheng-yong Yang, Jie Zhang, Linli Li, 2020, European journal of medicinal chemistry.

Discovery of 4H-chromen-4-one Derivatives as a New Class of Selective Rho Kinase (ROCK) Inhibitors, Which Showed Potent Activity in Ex Vivo Diabetic Retinopathy Models.

Sheng-yong Yang, Danian Chen, Chenyu Tian, 2019, Journal of medicinal chemistry.

The influence of music environment on conceptual design creativity

Tiansheng Xia, Linli Li, Y. An, 2023, Frontiers in Psychology.

Design, synthesis, and biological screening of a series of pyrazolo [1,5-a]quina-zoline derivatives as SIRT6 activators.

Linli Li, Ziling Zhang, Z. Fang, 2023, European Journal of Pharmaceutical Sciences.

Brushite-coated Mg-Nd-Zn-Zr alloy promotes the osteogenesis of vertebral laminae through IGF2/PI3K/AKT signaling pathway.

Feizhou Lyu, G. Yuan, Linli Li, 2023, Biomaterials advances.

Bioorthogonal "Click Chemistry" Bone Cement with Bioinspired Natural Mimicking Microstructures for Bone Repair.

Lichun Lu, B. Elder, A. Rezaei, 2023, ACS biomaterials science & engineering.

3D-printed scaffolds with 2D hetero-nanostructures and immunomodulatory cytokines provide pro-healing microenvironment for enhanced bone regeneration

A. Terzic, Lichun Lu, B. Elder, 2023, Bioactive materials.

Discovery of 5-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrazin-2(1H)-one derivatives as new potent PB2 inhibitors.

Sheng-yong Yang, Tianqi Wang, Luyi Huang, 2019, Bioorganic & medicinal chemistry letters.

The Role of Cerebrospinal Fluid Pulsation Stress in the Remodeling of Vertebral Laminae

Linli Li, Yiqun He, Youhai Dong, 2018 .

Comparative analysis of mesenchymal stromal cells derived from rabbit bone marrow and Wharton’s jelly for adipose tissue engineering

Feizhou Lyu, Linli Li, Jian Dong, 2019, Connective tissue research.

Comparison of Stemness and Immunogenicity of Osteo-Differentiated Mesenchymal Stem Cells Derived from Rabbit Bone Marrow and Wharton's Jelly

Linli Li, Yuan Yuan, Youhai Dong, 2017 .

Comparison of Proliferative and Multilineage Differentiation Potential of Rabbit Bone Marrow Mesenchymal Stem Cells and Wharton's Jelly Mesenchymal Stem Cells

Linli Li, Yiqun He, Youhai Dong, 2017 .

Bifunctional hydrogel for potential vascularized bone tissue regeneration.

Lichun Lu, E. Camilleri, Linli Li, 2021, Materials science & engineering. C, Materials for biological applications.

Spatial and uniform deposition of cell-laden constructs on 3D printed composite phosphorylated hydrogels for improved osteoblast responses

Lichun Lu, M. Tilton, Linli Li, 2021, Journal of Materials Science.

Exosomes derived from autologous dermal fibroblasts promote diabetic cutaneous wound healing through the Akt/β-catenin pathway

Yi Wang, Linli Li, H. Qian, 2021, Cell cycle.

Geninthiocins C and D from Streptomyces as 35-membered macrocyclic thiopeptides with modified tail moiety

Xuefu You, Liyan Yu, Linli Li, 2018, Journal of antibiotics (Tokyo. 1968).

Discovery and structure-activity relationship studies of novel α-ketoamide derivatives targeting the SARS-CoV-2 main protease.

Yifei Wang, Linli Li, Jian Lei, 2023, European journal of medicinal chemistry.

Discovery of Pyrrolo[3,2- d]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain.

P. Brennan, Sheng-yong Yang, Luyi Huang, 2019, Journal of medicinal chemistry.

1-hydroxy-7-oxolavanducyanin and Δ7″,8″-6″-hydroxynaphthomevalin from Streptomyces sp. CPCC 203577

Liyan Yu, Jing Wang, Xiaowen Hu, 2020, The Journal of Antibiotics.

Discovery of 5-((1H-indazol-3-yl) methylene)-2-thioxoimidazolidin-4-one derivatives as a new class of AHR agonists with anti-psoriasis activity in a mouse model.

Chenyu Tian, Linli Li, Jie Liu, 2023, Bioorganic & medicinal chemistry letters.

Α-MMC and MAP30, two ribosome-inactivating proteins extracted from Momordica charantia, induce cell cycle arrest and apoptosis in A549 human lung carcinoma cells.

Yao Meng, Y. Meng, Linli Li, 2015, Molecular medicine reports.